UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y43C5A.2	Y43C5A.2	0	chrIV 10,271,258	contains similarity to Pfam domain PF00147 Fibrinogen beta and gamma chains, C-terminal globular domain contains similarity to Interpro domains IPR013048 (Meiotic recombination Spo11), IPR014716 (Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1), IPR002181 (Fibrinogen, alpha/beta/gamma chain, C-terminal globular)
2	R05F9.6	R05F9.6	n/a	chrII 4,890,420	contains similarity to Pfam domains PF02879 (Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II) , PF02878 (Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I) , PF02880 (Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III) , PF00408 (Phosphoglucomutase/phosphomannomutase, C-terminal domain) contains similarity to Interpro domains IPR016066 (Alpha-D-phosphohexomutase, conserved site), IPR005843 (Alpha-D-phosphohexomutase, C-terminal), IPR016055 (Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III), IPR005841 (Alpha-D-phosphohexomutase, N-terminal), IPR005844 (Alpha-D-phosphohexomutase, alpha/beta/alpha domain I), IPR005846 (Alpha-D-phosphohexomutase, alpha/beta/alpha domain III), IPR005845 (Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)
3	K02G10.3	K02G10.3	n/a	chrX 4,675,475	contains similarity to Rattus norvegicus Transmembrane protein 135.; SW:Q5U4F4
4	bcat-1	K02A4.1	n/a	chrX 12,878,825	bcat-1 encodes a branched-chain amino acid aminotransferase that, by homology, is predicted to catalyze the first reaction in the catabolism of essential branched-chain amino acids such as leucine, isoleucine, and valine; in C. elegans, large-scale RNA-mediated interference (RNAi) screens indicate that bcat-1 activity is required for embryonic and larval development.
5	F25B4.1	F25B4.1	n/a	chrV 5,713,763	F25B4.1 is orthologous to the human gene GLYCINE CLEAVAGE SYSTEM T-PROTEIN (AMT; OMIM:238310), which when mutated leads to glycine encephalopathy.
6	cdr-2	C54D10.1	n/a	chrV 12,415,171	C. elegans CDR-2 protein; contains similarity to Pfam domain PF00043 Glutathione S-transferase, C-terminal domain contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
7	ugt-1	AC3.7	n/a	chrV 10,396,677	C. elegans UGT-1 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
8	btb-14	Y57A10B.3	n/a	chrII 12,383,995	C. elegans BTB-14 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
9	Y70C5A.2	Y70C5A.2	n/a	chrV 16,622,275	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	F54D5.4	F54D5.4	n/a	chrII 11,570,295	contains similarity to Haemonchus contortus NIM-2 protein.; TR:Q4QYX5
11	C25F9.4	C25F9.4	n/a	chrV 19,412,581	contains similarity to Arabidopsis thaliana Putative SWI/SNF-related matrix-associated actin-dependent regulatorsof chromatin subfamily A member 3-like 3 (EC 3.6.1.-) (SMARCA3-likesprotein 3).; SW:Q9FIY7
12	B0286.3	B0286.3	n/a	chrII 4,371,091	contains similarity to Pfam domains PF01259 (SAICAR synthetase) , PF00731 (AIR carboxylase) contains similarity to Interpro domains IPR001636 (SAICAR synthetase), IPR000031 (1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase), IPR013816 (ATP-grasp fold, subdomain 2)
13	kqt-2	M60.5	n/a	chrX 8,244,691	kqt-2 encodes one of three C. elegans KCNQ-like potassium channel subunits for which mutations in humans are associated with heredity diseases that affect epithelial cells, cardiac muscle and neurons; a KQT-2::GFP fusion protein is expressed exclusively in the intestine.
14	hum-5	T02C12.1	n/a	chrIII 4,032,950	C. elegans HUM-5 protein; contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) , PF06017 (Myosin tail) , PF00063 (Myosin head (motor domain)) contains similarity to Interpro domains IPR010926 (Myosin tail 2), IPR000048 (IQ calmodulin-binding region), IPR001609 (Myosin head, motor region)
15	irs-1	R11A8.6	n/a	chrIV 10,370,700	irs-1 encodes a predicted cytoplasmic isoleucyl-tRNA synthetase (IleRS), an aminoacyl-tRNA synthetase that catalyzes the attachment of isoleucine to its cognate tRNA and is thus required for protein biosynthesis; loss of irs-1 activity via RNA-mediated interference (RNAi) results in sterility, embryonic lethality, and slower rates of growth, indicating that IRS-1 is essential for development.
16	C49C3.9	C49C3.9	n/a	chrIV 17,340,941	contains similarity to Brassaiopsis tripteris NADH dehydrogenase subunit F (Fragment).; TR:Q85UX5
17	col-150	B0024.2	n/a	chrV 10,294,098	C. elegans COL-150 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
18	Y17D7B.4	Y17D7B.4	n/a	chrV 18,776,427
19	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
20	R07E3.4	R07E3.4	n/a	chrX 10,331,226	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
21	K04A8.1	K04A8.1	n/a	chrV 6,567,604	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
22	M04C3.2	M04C3.2	n/a	chrV 19,447,361	contains similarity to Arabidopsis thaliana Putative SWI/SNF-related matrix-associated actin-dependent regulatorsof chromatin subfamily A member 3-like 3 (EC 3.6.1.-) (SMARCA3-likesprotein 3).; SW:Q9FIY7
23	T04F3.1	T04F3.1	n/a	chrV 11,747,105	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR001176 (1-aminocyclopropane-1-carboxylate synthase), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
24	B0272.3	B0272.3	n/a	chrX 9,432,002	contains similarity to Pfam domains PF00725 (3-hydroxyacyl-CoA dehydrogenase, C-terminal domain) , PF02737 (3-hydroxyacyl-CoA dehydrogenase, NAD binding domain) contains similarity to Interpro domains IPR013328 (Dehydrogenase, multihelical), IPR008927 (6-phosphogluconate dehydrogenase, C-terminal-like), IPR006176 (3-hydroxyacyl-CoA dehydrogenase, NAD binding), IPR006168 (NAD-dependent glycerol-3-phosphate dehydrogenase), IPR006108 (3-hydroxyacyl-CoA dehydrogenase, C-terminal), IPR006180 (3-hydroxyacyl-CoA dehydrogenase, conserved site), IPR016040 (NAD(P)-binding), IPR006036 (Potassium uptake protein TrkA)
25	C06G8.1	C06G8.1	n/a	chrIV 10,779,821	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domains IPR004316 (MtN3 and saliva related transmembrane protein), IPR003091 (Voltage-dependent potassium channel)
26	H03A11.2	H03A11.2	n/a	chrX 15,228,166	contains similarity to Trypanosoma brucei Putative uncharacterized protein.; TR:Q57WE8
27	T07C12.9	T07C12.9	n/a	chrV 9,957,579	contains similarity to Pfam domain PF01234 NNMT/PNMT/TEMT family contains similarity to Interpro domain IPR000940 (Methyltransferase, NNMT/PNMT/TEMT)
28	F13B12.2	F13B12.2	n/a	chrIV 10,427,657	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001991 (Sodium:dicarboxylate symporter), IPR001411 (Tetracycline resistance protein, TetB), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
29	Y54G11A.7	Y54G11A.7	n/a	chrII 14,298,367	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR000023 (Phosphofructokinase)
30	gly-13	B0416.6	n/a	chrX 9,295,081	gly-13 encodes an experimentally verified UDP-N-acetylglucosamine alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I (GnT I), that is the primary GnT I enzyme in vivo, and that can act on unusual substrates; gly-13 is expressed throughout development in many cell types; gly-13 has no obvious function in vivo, since a deletion allele of gly-13 is phenotypically normal even as a double or triple mutant with gly-12 and gly-14.
31	C17H12.4	C17H12.4	n/a	chrIV 6,800,609	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
32	K10D11.6	K10D11.6	n/a	chrIV 12,988,061	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
33	C28H8.3	C28H8.3	n/a	chrIII 5,911,573	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) , PF04851 (Type III restriction enzyme, res subunit) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR006935 (Restriction endonuclease, type I, R subunit/Type III, Res subunit), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR008162 (Inorganic pyrophosphatase), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
34	C05D11.1	C05D11.1	n/a	chrIII 6,438,225	contains similarity to Pfam domains PF00675 (Insulinase (Peptidase family M16)) , PF05193 (Peptidase M16 inactive domain) (2)contains similarity to Interpro domains IPR011765 (Peptidase M16, N-terminal), IPR011237 (Peptidase M16, core), IPR007863 (Peptidase M16, C-terminal), IPR011249 (Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)
35	ZK1307.8	ZK1307.8	n/a	chrII 9,625,448	contains similarity to Pfam domains PF07915 (Glucosidase II beta subunit-like protein) , PF00036 (EF hand) contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR001907 (Peptidase S14, ClpP), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR009011 (Mannose-6-phosphate receptor, binding), IPR000886 (Endoplasmic reticulum, targeting sequence), IPR012913 (Glucosidase II beta subunit-like)
36	C05D2.8	C05D2.8	n/a	chrIII 5,608,885	contains similarity to Aedes aegypti Putative uncharacterized protein (Fragment).; TR:Q16Z88
37	C03H12.1	C03H12.1	n/a	chrX 15,692,830	contains similarity to Interpro domain IPR012336 (Thioredoxin-like fold)
38	cyp-35A2	C03G6.15	n/a	chrV 7,363,242	C. elegans CYP-35A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
39	C44C8.3	C44C8.3	n/a	chrIV 896,078	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
40	rps-23	F28D1.7	n/a	chrIV 12,390,663	rps-23 encodes a small ribosomal subunit S23 protein; by homology, RPS-23 is predicted to function in protein biosynthesis; in C. elegans, RPS-23 activity is required for germline development, vulval morphogenesis, and the overall health of the animal.
41	H23N18.4	H23N18.4	n/a	chrV 4,902,178	contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
42	asg-2	C53B7.4	n/a	chrX 6,841,624	asg-2 encodes a homolog of subunit G of the membrane-bound F0 proton channel portion of ATP synthase (mitochondrial respiratory chain [MRC] complex V); asg-2 activity is required for growth at a normally high rate and for normal osmoregulation; in addition, asg-2 activity is required for response to hermaphrodite contact, the first step in a series of stereotypical male mating behaviors; an ASG-2::GFP fusion localizes to mitochondria and to cilia of the male-specific CEM neurons.
43	D1054.8	D1054.8	n/a	chrV 10,784,796	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
44	R10H10.3	R10H10.3	n/a	chrIV 10,390,865	contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00431 (CUB domain) contains similarity to Interpro domains IPR000859 (CUB), IPR016857 (Uncharacterised conserved protein UCP027682, CUB, vWA), IPR002035 (von Willebrand factor, type A)
45	his-7	F45F2.4	n/a	chrV 8,533,548	his-7 encodes an H2A histone.
46	F21A3.3	F21A3.3	n/a	chrV 15,518,665	F21A3.3 encodes a putatively secreted protein, with an N-terminal EGF-liked domain and a DUF1794 domain, that is homologous to human THAP4/CGI-36; F21A3.3 is a paralog of MAB-7, C15F1.1, C28H8.5, C52G5.2, T28H10.2, and a domain in Y46G5A.29.
47	T01E8.5	T01E8.5	n/a	chrII 10,245,041	contains similarity to Pfam domain PF08424 Protein of unknown function (DUF1740) contains similarity to Interpro domain IPR013633 (Protein of unknown function DUF1740)
48	K07H8.3	K07H8.3	n/a	chrIV 8,290,863	contains similarity to Pfam domain PF00583 Acetyltransferase (GNAT) family contains similarity to Interpro domains IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase)
49	K05F1.10	K05F1.10	n/a	chrII 5,805,057	K05F1.10 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; K05F1.10 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; although it has no obvious function in mass RNAi assays, K05F1.10 transcription is reproducibly induced by infection, suggesting that it may participate in innate immunity.
50	folt-2	F37B4.7	n/a	chrV 2,874,024	folt-2 encodes a putative folate transporter; FOLT-2 is orthologous to human SLC19A1 (OMIM:600424), SLC19A2 (OMIM:603941, mutated in thiamine-responsive megaloblastic anemia syndrome), and SLC19A3 (OMIM:606152, mutated in biotin-responsive basal ganglia disease); heterologously expressed FOLT-2 does not significantly transport folate; FOLT-2 has no obvious function in mass RNAi assays, perhaps because of genetic redundancy with its paralogs FOLT-1 and FOLT-3.