UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y39A3A.4	Y39A3A.4	0	chrIII 2,074,752	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
2	F22E5.6	F22E5.6	n/a	chrII 2,650,293	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
3	nhr-6	C48D5.1	n/a	chrIII 3,576,162	nhr-6 encodes a nuclear receptor of the NR4A4 subfamily that is orthologous to the mammalian NGFI-B receptors and the Drosophila HR38 nuclear receptor (DHR38) that has been implicated in molting and metamorphosis; by homology, NHR-6 likely functions as a transcription factor that, based upon RNAi experiments, is required for normal ovulation and/or spermathecal development or function; an nhr-6 reporter fusion is expressed primarily in the anterior and posterior spermatheca during L3 and L4 larval stages, with some weak and variable expression also observed in two chemosensory neurons; nhr-6 mRNA is expressed in an oscillating manner throughout larval development, in a pattern that is slightly irregular with respect to the timing of larval molts and that exhibits consistently lower expression at the times when these molts actually occur.
4	F20D1.3	F20D1.3	n/a	chrX 14,977,334	contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR000018 (P2Y4 purinoceptor), IPR015915 (Kelch-type beta propeller)
5	C26F1.6	C26F1.6	n/a	chrV 7,772,218	C26F1.6 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C26F1.6 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
6	tig-2	F39G3.8	n/a	chrV 4,728,435	The tig-2 gene, like dbl-1, daf-7, and unc-129, encodes a TGF-beta-like protein.
7	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
8	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
9	T02D1.6	T02D1.6	n/a	chrIV 17,410,914	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002232 (5-Hydroxytryptamine 6 receptor), IPR000276 (GPCR, rhodopsin-like)
10	F26A1.8	F26A1.8	n/a	chrIII 4,821,475	contains similarity to Interpro domain IPR000010 (Proteinase inhibitor I25, cystatin)
11	cyp-13A8	T10B9.4	n/a	chrII 9,806,501	C. elegans CYP-13A8 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
12	C50C3.5	C50C3.5	n/a	chrIII 8,179,701	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000261 (EPS15 homology (EH))
13	unc-14	K10D3.2	n/a	chrI 7,125,516	The unc-14 gene encodes an activity required for both axonogenesis and sex myoblast migration.
14	H04M03.12	H04M03.12	n/a	chrIV 5,900,480
15	K02F6.5	K02F6.5	n/a	chrII 2,535,834	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
16	F20D6.8	F20D6.8	n/a	chrV 8,166,494	contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
17	VM106R.1	VM106R.1	n/a	chrII 10,828,708	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
18	C31H2.3	C31H2.3	n/a	chrX 5,152,942
19	sue-1	F07A5.5	n/a	chrI 7,365,960	C. elegans SUE-1 protein; contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR013032 (EGF-like region, conserved site)
20	B0024.3	B0024.3	n/a	chrV 10,288,395	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
21	ZK218.5	ZK218.5	n/a	chrV 17,101,526	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
22	K11H3.5	K11H3.5	n/a	chrIII 9,844,623	contains similarity to Homo sapiens Splice isoform 1 of P49321 Nuclear autoantigenic sperm protein; ENSEMBL:ENSP00000320980
23	mlt-8	W08F4.6	n/a	chrII 570,690	mlt-8 encodes a novel protein; during development, mlt-8 activity is required for molting; a mlt-8::gfp reporter is expressed in hypodermal cells and in a single posterior neuron.
24	gab-1	ZC482.1	n/a	chrIII 12,775,682	gab-1 encodes a gamma-aminobutyric acid (GABA) receptor beta-like subunit with both the neurotransmitter-gated ion-channel ligand binding and transmembrane domains; gab-1 can form a GABA-responsive channel when co-expressed with alpha/gamma type subunits in a heterologous expression system; experiments with gab-1 indicate that GABA receptors are involved in the mechanism of resistance to the widely used broad-spectrum anthelmintic drug Ivermectin.
25	K11H12.3	K11H12.3	n/a	chrIV 672,557	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
26	cyp-33C7	F41B5.2	n/a	chrV 2,251,536	C. elegans CYP-33C7 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
27	str-66	Y73C8C.5	n/a	chrV 3,103,680	C. elegans STR-66 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	Y52B11A.4	Y52B11A.4	n/a	chrI 10,991,938	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily), IPR002078 (RNA polymerase sigma factor 54, interaction)
29	gpa-2	F38E1.5	n/a	chrV 8,372,499	gpa-2 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that is involved in dauer formation and chemotaxis to water-soluble odorants; it is expressed in the phasmid neurons PHA and PHB, three pharyngeal neurons, one interneuron, three pairs of head neurons, and the anal sphincter muscle.
30	F23H11.7	F23H11.7	n/a	chrIII 918,259
31	M163.1	M163.1	n/a	chrX 14,503,087	contains similarity to Mus musculus Adapter-related protein complex 3 beta 1 subunit (Beta-adaptin 3A)s(AP-3 complex beta-3A subunit) (Beta-3A-adaptin).; SW:A3B1_MOUSE
32	F20A1.4	F20A1.4	n/a	chrV 7,020,334
33	nhr-120	C25B8.6	n/a	chrX 6,638,552	C. elegans NHR-120 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
34	srx-45	K01B6.2	n/a	chrIII 9,305,269	C. elegans SRX-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
35	F25D7.5	F25D7.5	n/a	chrI 10,425,982	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF07974 (EGF-like domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular)
36	T04B2.5	T04B2.5	n/a	chrIV 10,057,860	contains similarity to Pfam domain PF01734 Patatin-like phospholipase contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin)
37	F57C9.6	F57C9.6	n/a	chrI 4,823,394	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
38	nhr-84	T06C12.7	n/a	chrV 15,878,178	C. elegans NHR-84 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
39	srbc-16	C45H4.1	n/a	chrV 2,182,614	C. elegans SRBC-16 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
40	K04F1.11	K04F1.11	n/a	chrV 1,660,979	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
41	nca-2	C27F2.2	n/a	chrIII 4,972,657	nca-2 encodes a novel, four-domain alpha1U Ca2+ channel subunit; nca-2 functions redundantly with a paralog, nca-1, to regulate locomotion and the response to specific volatile anesthetics; in regulating these processes, nca-1 and nca-2 function in the same pathway as unc-79, which encodes a conserved novel protein that positively regulates levels of NCA-1 and NCA-2 protein; nca-2::gfp reporters are expressed in the nervous system in a few pharyngeal neurons, many nerve ring interneurons, most ventral nerve motor cord neurons, and in neurons and muscles in the tail; diffuse expression is also seen in vulval muscles and the intestine.
42	C37H5.2	C37H5.2	n/a	chrV 4,848,674	contains similarity to Pfam domain PF00561 alpha/beta hydrolase fold contains similarity to Interpro domains IPR000073 (Alpha/beta hydrolase fold-1), IPR000639 (Epoxide hydrolase-like), IPR003089 (Alpha/beta hydrolase), IPR002410 (Peptidase S33, prolyl aminopeptidase)
43	set-11	F34D6.4	n/a	chrII 2,692,391	set-11 encodes a putative histone H3 lysine-9 methyltransferase orthologous to human EHMT1 (OMIM:607001, mutated in 9q subtelomeric deletion syndrome) and EHMT2 (OMIM:604599); neither set-11(n4488) nor set-11(RNAi) have any obvious phenotypes.
44	twk-40	T28A8.1	n/a	chrIII 13,487,791	C. elegans TWK-40 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR003938 (Potassium channel, voltage-dependent, EAG/ELK/ERG), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
45	C54D10.3	C54D10.3	n/a	chrV 12,418,939	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
46	fbxa-115	Y113G7B.3	n/a	chrV 20,186,739	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
47	F42A8.1	F42A8.1	n/a	chrII 9,343,914	contains similarity to Yersinia pestis ORF4.; TR:Q9RPN3
48	C55A6.6	C55A6.6	n/a	chrV 11,514,222	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
49	nas-25	F46C5.3	n/a	chrII 8,827,065	nas-25 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-25::GFP promoter fusion is expressed in the pharynx and pharyngeal-intestinal valve.
50	sup-9	F34D6.3	n/a	chrII 2,685,863	sup-9 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; sup-9 was originally defined by gain-of-function mutations that result in defects in pharyngeal, body-wall, egg-laying, and enteric muscle activation; loss of sup-9 function via reversion or RNA-mediated interference (RNAi) does not result in any abnormalities suggesting that SUP-9 may function redundantly with other TWK channels; SUP-9 is expressed in neurons and muscle.