UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cey-4	Y39A1C.3	6e-98	chrIII 10,867,771	cey-4 encodes a Y box-containing protein with no known function in vivo; CEY-4 associates with CGH-1 and CEY-2/3 in cytoplasmic particles of the gonad and early embryo.
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	Y39A1A.16	Y39A1A.16	n/a	chrIII 10,680,725	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
4	mec-14	F37C12.12	n/a	chrIII 7,191,528	mec-14 encodes a protein with similarity to the beta-subunits of Shaker-type potassium channels, which are members of the aldo-keto reductase superfamily; MEC-14 is required for response to gentle touch by the six touch receptor neurons, and likely functions to regulate activity of the MEC-4 and MEC-10 degenerin channels; mec-14 expression is detected solely in the touch receptor neurons and is dependent on the MEC-3 LIM domain transcription factor; proper MEC-14 localization in the touch receptor neurons is dependent on MEC-12/alpha-tubulin.
5	W06E11.1	W06E11.1	n/a	chrIII 643,797	contains similarity to Pfam domain PF04801 Sin-like protein conserved region contains similarity to Interpro domain IPR006886 (Sin-like protein conserved region)
6	uri-1	C55B7.5	n/a	chrI 6,495,201	uri-1 encodes a molecular chaperone orthologous to the unconventional prefoldin RPB5 (RNA polymerase subunit 5) interactor, URI; in C.elegans, URI-1 activity is required for suppressing endogenous genotoxic DNA damage and thus, is essential for maintenance of genome integrity (DNA stability) and progression through the mitotic and meiotic cell cycles, particularly during germ cell development; URI-1 activity is also required for development of some somatic structures, such as the vulva, and for RNA interference; uri-1 mRNA is germline-enriched.
7	C05E7.2	C05E7.2	n/a	chrX 12,939,625
8	Y23H5A.2	Y23H5A.2	n/a	chrI 2,622,537	Y23H5A.2 encodes a Caenorhabditis-specific protein, without obvious similarities or motifs; Y23H5A.2 inhibits CEP-1- and HUS-1-dependent germline apoptosis, as do BMK-1, RAD-50, and RAD-51.
9	ZK287.7	ZK287.7	n/a	chrV 9,693,782	contains similarity to Homo sapiens Isoform 2 of RNA pseudouridylate synthase domain-containing protein 3; ENSEMBL:ENSP00000380410
10	K03D7.8	K03D7.8	n/a	chrV 17,490,522
11	Y57G11C.25	Y57G11C.25	n/a	chrIV 14,919,983	Y57G11C.25 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of Y57G11C.25 is predicted to function as an RNA-binding protein.
12	lsm-7	ZK593.7	n/a	chrIV 10,933,821	C. elegans LSM-7 protein; contains similarity to Pfam domain PF01423 LSM domain contains similarity to Interpro domains IPR001163 (Like-Sm ribonucleoprotein, core), IPR006649 (Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core), IPR010920 (Like-Sm ribonucleoprotein-related, core), IPR017132 (U6 snRNA-associated Sm-like protein LSm7)
13	srx-111	T24E12.4	n/a	chrII 3,758,519	C. elegans SRX-111 protein ;
14	B0001.7	B0001.7	n/a	chrIV 12,152,686	contains similarity to Herpestes ichneumon Acetylcholine receptor protein, alpha chain (Fragment).; SW:ACHA_HERIC
15	C49F5.6	C49F5.6	n/a	chrX 11,989,713	contains similarity to Homo sapiens Ankyrin 3; ENSEMBL:ENSP00000280772
16	F25H5.5	F25H5.5	n/a	chrI 9,161,573	F25H5.5 encodes the C. elegans homologue of Claspin, an S-phase checkpoint component that interacts with Chk1 and negatively regulates cell cycle progression; in wild-type animals, loss of F25H5.5 activity results in some embryonic lethality; loss of F25H5.5 activity in a lin-35 mutant background, however, results in sterility, as well as smaller than normal body size, uncoordinated locomotion, and a protruding vulva; weaker F25H5.5 RNAi phenotypes are seen in lin-15B and eri-1; lin-15B backgrounds.
17	K11B4.2	K11B4.2	n/a	chrI 14,798,156	contains similarity to Tetraodon nigroviridis UPF0402 protein.; SW:Q4S3C1
18	Y18D10A.16	Y18D10A.16	n/a	chrI 12,903,539	contains similarity to Homo sapiens Uncharacterized protein C2orf64; ENSEMBL:ENSP00000330730
19	sel-12	F35H12.3	n/a	chrX 917,054	sel-12 encodes a transmembrane domain protein orthologous to presenilins; during gonadal, germline, and vulval development, sel-12 functions, within receiving cells, to positively regulate lin-12 and glp-1 Notch-like signaling pathways; sel-12 presenilin activity and/or levels are likely regulated by the SET/NAP protein sub-family member encoded by spr-2, as mutations in sel-12 are suppressed by mutations in spr-2; spr-2 regulation of sel-12 occurs in a hop-1 presenilin dependent manner.
20	ZC513.5	ZC513.5	n/a	chrV 8,037,288	contains similarity to Pfam domain PF03901 Alg9-like mannosyltransferase family contains similarity to Interpro domain IPR005599 (Alg9-like mannosyltransferase)
21	F02H6.2	F02H6.2	n/a	chrIV 14,197,604	contains similarity to Trichomonas vaginalis G3 Putative uncharacterized protein.; TR:A2F8N8
22	pstk-1	Y49E10.22	n/a	chrIII 12,467,328	C. elegans PSTK-1 protein; contains similarity to Pfam domain PF08433 Chromatin associated protein KTI12 contains similarity to Interpro domain IPR013641 (Chromatin associated protein KTI12)
23	Y47H9C.12	Y47H9C.12	n/a	chrI 11,896,823	contains similarity to Escherichia coli O6 FMN reductase (EC 1.5.1.29).; TR:Q8FJ92
24	fbxa-185	F47H4.4	n/a	chrV 17,333,561	C. elegans FBXA-185 protein; contains similarity to Pfam domains PF01485 (IBR domain) , PF00097 (Zinc finger, C3HC4 type (RING finger)) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002867 (Zinc finger, C6HC-type)
25	F16H6.9	F16H6.9	n/a	chrV 18,219,656	contains similarity to Mus musculus Calpain 6.; SW:CAN6_MOUSE
26	JC8.7	JC8.7	n/a	chrIV 13,248,845	contains similarity to Homo sapiens Uncharacterized protein C4orf27; ENSEMBL:ENSP00000261511
27	C06A8.2	C06A8.2	n/a	chrII 7,780,233	contains similarity to Homo sapiens snRNA-activating protein complex subunit 1; ENSEMBL:ENSP00000216294
28	C48E7.2	C48E7.2	n/a	chrI 6,256,337	contains similarity to Pfam domains PF08221 (RNA polymerase III subunit RPC82 helix-turn-helix domain) , PF05645 (RNA polymerase III subunit RPC82) contains similarity to Interpro domains IPR013197 (RNA polymerase III subunit RPC82-related, helix-turn-helix), IPR008806 (RNA polymerase III Rpc82, C -terminal)
29	C43F9.7	C43F9.7	n/a	chrIV 10,593,293	contains similarity to Xanthomonas campestris Hypothetical protein XCC1495.; TR:Q8PAI8
30	T12A2.1	T12A2.1	n/a	chrIII 6,261,458	contains similarity to Pfam domains PF01979 (Amidohydrolase family) , PF07969 (Amidohydrolase family) contains similarity to Interpro domains IPR011550 (Amidohydrolase-like), IPR013108 (Amidohydrolase 3), IPR006680 (Amidohydrolase 1), IPR005920 (Imidazolonepropionase)
31	msp-38	K08F4.8	n/a	chrIV 10,143,514	msp-38 encodes a member of the major sperm protein family; msp-38 has a C. briggsae homolog as predicted by the Wobble Bulk Aware Bulk Aligner (WABA).
32	sdz-6	C43D7.5	n/a	chrV 19,320,877	C. elegans SDZ-6 protein ; contains similarity to Dictyostelium discoideum AAC-rich mRNA clone AAC11 protein.; SW:P14196
33	Y40H7A.3	Y40H7A.3	n/a	chrIV 15,162,987	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
34	sid-1	C04F5.1	n/a	chrV 5,123,427	The sid-1 gene encodes a predicted transmembrane protein with conserved human (OMIM:606816) and mouse homologs of unknown function and is required cell autonomously for systemic RNA interference (RNAi); a SID-1::GFP fusion is enriched at the cell periphery of most nonneuronal cells from late embryogenesis through adulthood with highest levels detected in cells exposed to the environment.
35	hum-1	F29D10.4	n/a	chrI 8,848,443	hum-1 encodes a class I unconventional myosin heavy chain that, within this class, is most closely related to the amoeboid myosin I subclass; loss of hum-1 activity via RNAi results in a low frequency of aldicarb resistance, suggesting that hum-1 may play a role in regulating synapse structure and/or function; when expressed in the DA cholinergic motor neurons, a HUM-1 reporter fusion protein localizes solely to punctate structures.
36	bath-7	F52C6.10	n/a	chrII 1,920,562	C. elegans BATH-7 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
37	spe-42	B0240.2	n/a	chrV 11,735,328	C. elegans SPE-42 protein; contains similarity to Pfam domain PF07782 DC-STAMP-like protein contains similarity to Interpro domain IPR012858 (DC-STAMP-like)
38	E02H9.6	E02H9.6	n/a	chrIII 2,439,204	contains similarity to Interpro domain IPR000694 (Proline-rich region)
39	T23B12.1	T23B12.1	n/a	chrV 8,469,517	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
40	R04B5.5	R04B5.5	n/a	chrV 10,088,214	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR011597 (GroES-related), IPR016040 (NAD(P)-binding), IPR002328 (Alcohol dehydrogenase, zinc-containing, conserved site)
41	C01F6.9	C01F6.9	n/a	chrIV 9,095,971	The C01F6.9 gene resides in an operon that also contains the genes icl-1 and lpl-1.
42	R07E4.5	R07E4.5	n/a	chrX 5,951,318	contains similarity to Plasmodium lophurae Histidine-rich glycoprotein precursor.; SW:P04929
43	R07E5.1	R07E5.1	n/a	chrIII 4,410,321	contains similarity to Pfam domains PF07713 (Protein of unknown function (DUF1604)) , PF01585 (G-patch domain) contains similarity to Interpro domains IPR011666 (Protein of unknown function DUF1604), IPR000467 (D111/G-patch), IPR005398 (Tubby, N-terminal)
44	K08H2.3	K08H2.3	n/a	chrX 13,237,815	contains similarity to Rattus norvegicus Inositol 1,4,5-trisphosphate 3-kinase C.; TR:Q80ZG2
45	H14E04.4	H14E04.4	n/a	chrIII 2,391,147
46	K12H4.2	K12H4.2	n/a	chrIII 8,047,973	contains similarity to Pfam domain PF02410 Domain of unknown function DUF143 contains similarity to Interpro domain IPR004394 (Iojap-related protein)
47	C24G6.3	C24G6.3	n/a	chrV 5,517,383	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
48	him-8	T07G12.12	n/a	chrIV 10,562,902	him-8 encodes a protein with two C-terminal noncanonical C2H2 zinc-fingers whose paralogs include ZIM-1/-3 and C02F5.12; HIM-8 is required by X chromosomes for normal homolog pairing, synapsis, recombination, and segregation during meiosis; him-8 mutants have an increased frequency of genotypically XO males in self-fertile hermaphrodite populations; HIM-8 is expressed during meiosis, and is associated with the X chromosome's meiotic pairing center (PC), which associates with the nuclear envelope during meiotic prophase; him-8 mutations are enhanced by rearrangements that inactivate the X-chromosomal PC; HIM-8 functions are genetically separable, since the him-8(me4) point mutation (which alters a domain N-terminal to HIM-8's zinc fingers) permits normal chromosome binding and nuclear localization, but causes abnormal pairing and synapsis; while the C-terminal region of HIM-8 most closely resembles those of its orthologs in other Caenorhabditis species, its N-terminal region is highly divergent, suggesting species-specific functions; unlike other him mutations, him-8 solely affects X chromosomes, and does not produce embryonic lethality via autosomal nondisjunction or aneuploidy; however, failure of X-chromosomal synapsis in him-8 mutants blocks the pachytene transistion from polarized to nonpolarized meiotic nuclei, by blocking the resolution of recombination intermediates on other chromosomes; him-8-blocked meiotic autosomes show persistent RAD-51 foci and have excess crossovers, both of which may be symptoms of a HUS-1-independent checkpoint induced by X-chromosomal nonsynapsis rather than DNA damage; HIM-8 also acts outside of meiosis, by inhibiting EGL-13 expression or activity; mutations of the HIM-8 zinc-finger domain semidominantly suppress missense (but not null) egl-13 mutations, due to him-8 haploinsufficiency; mutant HIM-8 fails to suppress mutant egl-13 on a free transgenic array, and also fails to suppress native mutant egl-13 if transgenic excess copies of the egl-13 promoter are present.
49	E02H1.2	E02H1.2	n/a	chrII 9,588,980	contains similarity to Pfam domain PF01926 GTPase of unknown function contains similarity to Interpro domains IPR009019 (K Homology, prokaryotic type), IPR003577 (Ras small GTPase, Ras type), IPR001806 (Ras GTPase), IPR002127 (Tetracycline resistance protein, TetO/TetQ/TetM), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG), IPR015946 (K homology-like, alpha/beta)
50	R11H6.5	R11H6.5	n/a	chrV 14,611,457	contains similarity to Pfam domain PF07528 DZF contains similarity to Interpro domains IPR006561 (DZF), IPR006116 (2-5-oligoadenylate synthetase, ubiquitin-like region)