UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y39A1C.1	Y39A1C.1	3.9999999999999995e-42	chrIII 10,857,346	contains similarity to Xylella fastidiosa Hypothetical protein Xf0776.; TR:Q9PFA2
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	cand-1	Y102A5A.1	n/a	chrV 16,808,692	C. elegans CAND-1 protein; contains similarity to Pfam domains PF02985 (HEAT repeat) (2), PF08623 (TATA-binding protein interacting (TIP20)) contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR013932 (TATA-binding protein interacting (TIP20)), IPR016024 (Armadillo-type fold)
4	sul-1	K09C4.8	n/a	chrX 3,269,056	sul-1 encodes a member of the sulfatase family.
5	chn-1	T09B4.10	n/a	chrI 6,182,743	chn-1 encodes an ortholog of mammalian carboxyl-terminus of Hsc70 interacting protein (CHIP), an E4 ubiquitin-chain elongation factor; chn-1 is ubiquitously expressed; chn-1(by155) mutants are viable and superficially normal, but have reduced fertility and arrest as larvae if subjected to heat shock; chn-1 overexpression causes either embryonic lethality (if strong) or defective egg-laying and locomotion, along with constitutive dauer formation (if weak); chn-1(by155) mutations suppress viable unc-45(e286ts) and unc-45(m94ts) mutations, but not lethal unc-45(st604) ones; chn-1(by155) mutants, unlike wild-type, show defective sarcomeres if overexpressing unc-45 from a extrachromosomal array; CHN-1 binds the ubiquitin conjugating enzyme UFD-2, which in turn binds the Hsp90 cochaperone UNC-45; UNC-45 is a substrate for CHN-1- and UFD-2-dependent multiubiquitination; the parkin ortholog PDR-1 binds CHN-1, and requires CHN-1 for self-ubiquitination; chn-1(RNAi) animals accumulate abnormally phosphorylated tau proteins.
6	T01B10.5	T01B10.5	n/a	chrX 8,496,580
7	nhr-165	C47F8.2	n/a	chrI 12,332,239	C. elegans NHR-165 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
8	zyg-8	Y79H2A.11	n/a	chrIII 12,066,888	The zyg-8 gene encodes a protein with a doublecortin-like domain and a protein kinase domain; mutations of zyg-8 impair mitosis at the one-cell embryonic stage, which is normally asymmetrical, but which fails to show proper asymmetry in zyg-8 mutant embryos.
9	F52G3.5	F52G3.5	n/a	chrX 16,974,629	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR006150 (Cysteine-rich repeat), IPR003582 (Metridin-like ShK toxin)
10	flr-1	F02D10.5	n/a	chrX 13,454,529	flr-1 encodes an ion channel that belongs to the DEG/ENaC sodium channel superfamily; flr-1 activity is essential for normal defecation rhythm, growth rates, expulsion, and dauer larvae formation; a rescuing FLR-1::GFP reporter is expressed in the intestine from embryonic to adult stages where it localizes to the membranes facing the inner lumen as well as to part of the lateral membrane between intestinal cells.
11	F49B2.3	F49B2.3	n/a	chrI 14,311,927	contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000694 (Proline-rich region)
12	F46C8.1	F46C8.1	n/a	chrX 7,550,722
13	F54B3.2	F54B3.2	n/a	chrII 10,269,583	contains similarity to Schizosaccharomyces pombe Hypothetical protein.; TR:Q9UT52
14	dpm-3	F28D1.11	n/a	chrIV 12,391,825	dpm-3 encodes a putative regulatory subunit of dolichol phosphate mannosyltransferase, orthologous to human DPM3 (OMIM:605951); in mass RNAi assays, DPM-3 is required for normal body size, fertility, and health.
15	T08G2.2	T08G2.2	n/a	chrX 17,207,313	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
16	R07C12.2	R07C12.2	n/a	chrIV 4,149,092
17	C34E7.4	C34E7.4	n/a	chrX 12,933,527	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
18	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
19	K08B5.1	K08B5.1	n/a	chrX 16,560,293
20	clec-118	W04H10.4	n/a	chrII 610,423	C. elegans CLEC-118 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
21	nas-1	F45G2.1	n/a	chrIII 13,407,525	nas-1 encodes an astacin-like metalloprotease.
22	nas-12	C24F3.3	n/a	chrIV 10,225,155	nas-12 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-12::GFP promoter fusion is expressed in the intestine and in the pharyngeal and rectal gland cells.
23	C23F12.4	C23F12.4	n/a	chrX 9,388,245
24	R04B3.2	R04B3.2	n/a	chrX 2,472,601	The R04B3.2 gene encodes an ortholog of the human gene LYSOSOMAL GLYCOSYLASPARAGINASE (AGA; OMIM:208400), which when mutated leads to aspartylglucosaminuria (OMIM:208400).
25	ZC513.1	ZC513.1	n/a	chrV 8,056,969	contains similarity to Pfam domain PF02886 LBP / BPI / CETP family, C-terminal domain contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
26	R05D7.5	R05D7.5	n/a	chrI 12,186,205	contains similarity to Ascaris suum P40.; TR:Q7YXJ9
27	ZC328.2	ZC328.2	n/a	chrI 6,389,348	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR007087 (Zinc finger, C2H2-type)
28	rhgf-2	T08H4.1	n/a	chrII 4,124,087	C. elegans RHGF-2 protein; contains similarity to Pfam domain PF00621 RhoGEF domain contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001849 (Pleckstrin-like), IPR000694 (Proline-rich region), IPR011993 (Pleckstrin homology-type), IPR015721 (Rho GTP exchange factor)
29	F22B7.1	F22B7.1	n/a	chrIII 8,666,020
30	ttb-1	W03F9.5	n/a	chrV 160,090	C. elegans TTB-1 protein; contains similarity to Pfam domains PF00382 (Transcription factor TFIIB repeat) (2), PF08271 (TFIIB zinc-binding) contains similarity to Interpro domains IPR006670 (Cyclin), IPR000812 (Transcription factor TFIIB related), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR013150 (Transcription factor TFIIB, cyclin-related), IPR013137 (Zinc finger, TFIIB-type)
31	E02H9.1	E02H9.1	n/a	chrIII 2,468,952
32	T13F2.9	T13F2.9	n/a	chrIV 9,768,468	contains similarity to Interpro domain IPR003071 (Orphan nuclear receptor, HMR type)
33	T21D11.1	T21D11.1	n/a	chrIII 7,246,672	contains similarity to Pfam domain PF00413 Matrixin contains similarity to Interpro domains IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR001818 (Peptidase M10A and M12B, matrixin and adamalysin)
34	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
35	F56D5.5	F56D5.5	n/a	chrIV 9,407,671	contains similarity to Interpro domain IPR000533 (Tropomyosin)
36	C11G10.1	C11G10.1	n/a	chrX 15,157,907
37	F52D1.2	F52D1.2	n/a	chrX 447,631
38	C49H3.9	C49H3.9	n/a	chrIV 7,908,266	contains similarity to Pfam domain PF07967 C3HC zinc finger-like contains similarity to Interpro domain IPR012935 (Zinc finger, C3HC-like)
39	dct-10	Y38H6C.5	n/a	chrV 20,503,211	C. elegans DCT-10 protein; contains similarity to Pfam domains PF03732 (Retrotransposon gag protein) , PF00098 (Zinc knuckle) contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR005162 (Retrotransposon gag protein), IPR001878 (Zinc finger, CCHC-type)
40	srh-266	F31F4.6	n/a	chrV 665,362	C. elegans SRH-266 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	K08F11.1	K08F11.1	n/a	chrIV 4,725,078
42	srv-11	H25K10.3	n/a	chrIV 16,220,615	C. elegans SRV-11 protein; contains similarity to Pfam domains PF01461 (7TM chemoreceptor) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002651 (Protein of unknown function DUF32)
43	tsr-1	F53G2.6	n/a	chrII 2,466,865	tsr-1 encodes a homolog of human transportin-SR, a nuclear transport receptor, and affects embryonic viability.
44	fbxb-47	F58E1.14	n/a	chrII 1,702,944	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
45	rnp-7	K04G7.10	n/a	chrIII 7,160,025	C. elegans RNP-7 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
46	T01A4.3	T01A4.3	n/a	chrI 4,465,379	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
47	cdc-42	R07G3.1	n/a	chrII 7,617,275	cdc-42 encodes a RHO GTPase which controls polarity of both individual cells and developing embryos by regulating the localization of PAR proteins; CDC-42 is expressed at hypodermal cell boundaries; cdc-42 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults.
48	K06H7.2	K06H7.2	n/a	chrIII 8,094,871	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
49	K07C11.4	K07C11.4	n/a	chrV 8,204,685	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
50	nhr-181	F38H12.3	n/a	chrV 4,097,665	nhr-181 encodes a putative nuclear hormone receptor (NHR), belonging to a large nematode-specific expanded family of NHRs, that inhibits CEP-1- and HUS-1-dependent germline apoptosis as do BMK-1, RAD-50, and RAD-51.