UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y39A1A.16	Y39A1A.16	0	chrIII 10,680,725	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
2	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
3	cey-4	Y39A1C.3	n/a	chrIII 10,867,771	cey-4 encodes a Y box-containing protein with no known function in vivo; CEY-4 associates with CGH-1 and CEY-2/3 in cytoplasmic particles of the gonad and early embryo.
4	Y57G11C.25	Y57G11C.25	n/a	chrIV 14,919,983	Y57G11C.25 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of Y57G11C.25 is predicted to function as an RNA-binding protein.
5	mec-14	F37C12.12	n/a	chrIII 7,191,528	mec-14 encodes a protein with similarity to the beta-subunits of Shaker-type potassium channels, which are members of the aldo-keto reductase superfamily; MEC-14 is required for response to gentle touch by the six touch receptor neurons, and likely functions to regulate activity of the MEC-4 and MEC-10 degenerin channels; mec-14 expression is detected solely in the touch receptor neurons and is dependent on the MEC-3 LIM domain transcription factor; proper MEC-14 localization in the touch receptor neurons is dependent on MEC-12/alpha-tubulin.
6	T14E8.2	T14E8.2	n/a	chrX 6,542,867	contains similarity to Interpro domain IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
7	F02D10.6	F02D10.6	n/a	chrX 13,450,586	contains similarity to Cryptophlebia leucotreta granulosis virus Hypothetical protein.; TR:Q7T5R9
8	F09A5.3	F09A5.3	n/a	chrX 13,151,561	contains similarity to Plasmodium falciparum Normocyte-binding protein 1.; TR:Q8WRS5
9	C43F9.7	C43F9.7	n/a	chrIV 10,593,293	contains similarity to Xanthomonas campestris Hypothetical protein XCC1495.; TR:Q8PAI8
10	cyn-12	C34D4.12	n/a	chrIV 7,132,656	cyn-12 encodes a member of the cyclophilin family that is related to human PPIL1 (CGI-124); based upon its sequence similarity, CYN-12 is predicted to be a cytoplasmic protein potentially involved in a wide range of signal transduction pathways.
11	srx-111	T24E12.4	n/a	chrII 3,758,519	C. elegans SRX-111 protein ;
12	C05E7.2	C05E7.2	n/a	chrX 12,939,625
13	him-8	T07G12.12	n/a	chrIV 10,562,902	him-8 encodes a protein with two C-terminal noncanonical C2H2 zinc-fingers whose paralogs include ZIM-1/-3 and C02F5.12; HIM-8 is required by X chromosomes for normal homolog pairing, synapsis, recombination, and segregation during meiosis; him-8 mutants have an increased frequency of genotypically XO males in self-fertile hermaphrodite populations; HIM-8 is expressed during meiosis, and is associated with the X chromosome's meiotic pairing center (PC), which associates with the nuclear envelope during meiotic prophase; him-8 mutations are enhanced by rearrangements that inactivate the X-chromosomal PC; HIM-8 functions are genetically separable, since the him-8(me4) point mutation (which alters a domain N-terminal to HIM-8's zinc fingers) permits normal chromosome binding and nuclear localization, but causes abnormal pairing and synapsis; while the C-terminal region of HIM-8 most closely resembles those of its orthologs in other Caenorhabditis species, its N-terminal region is highly divergent, suggesting species-specific functions; unlike other him mutations, him-8 solely affects X chromosomes, and does not produce embryonic lethality via autosomal nondisjunction or aneuploidy; however, failure of X-chromosomal synapsis in him-8 mutants blocks the pachytene transistion from polarized to nonpolarized meiotic nuclei, by blocking the resolution of recombination intermediates on other chromosomes; him-8-blocked meiotic autosomes show persistent RAD-51 foci and have excess crossovers, both of which may be symptoms of a HUS-1-independent checkpoint induced by X-chromosomal nonsynapsis rather than DNA damage; HIM-8 also acts outside of meiosis, by inhibiting EGL-13 expression or activity; mutations of the HIM-8 zinc-finger domain semidominantly suppress missense (but not null) egl-13 mutations, due to him-8 haploinsufficiency; mutant HIM-8 fails to suppress mutant egl-13 on a free transgenic array, and also fails to suppress native mutant egl-13 if transgenic excess copies of the egl-13 promoter are present.
14	F14H3.3	F14H3.3	n/a	chrV 16,052,681	contains similarity to Homo sapiens Trichohyalin; ENSEMBL:ENSP00000357794
15	Y18D10A.16	Y18D10A.16	n/a	chrI 12,903,539	contains similarity to Homo sapiens Uncharacterized protein C2orf64; ENSEMBL:ENSP00000330730
16	R07E4.5	R07E4.5	n/a	chrX 5,951,318	contains similarity to Plasmodium lophurae Histidine-rich glycoprotein precursor.; SW:P04929
17	R10E4.6	R10E4.6	n/a	chrIII 4,294,138
18	T19D12.7	T19D12.7	n/a	chrII 6,648,354	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
19	H14E04.4	H14E04.4	n/a	chrIII 2,391,147
20	K03D7.8	K03D7.8	n/a	chrV 17,490,522
21	F18E2.1	F18E2.1	n/a	chrV 12,758,672	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR015914 (Purple acid phosphatase, N-terminal), IPR004843 (Metallophosphoesterase)
22	mop-25.3	T27C10.3	n/a	chrI 10,891,011	mop-25.3 encodes a divergent ortholog of fission yeast Mo25p, budding yeast Hym1p, Aspergillus nidulans HymA, human CAB39, and human CAB39L; MOP-25.3 is paralogous to MOP-25.1 and MOP-25.2; MOP-25.3 is required for embryonic development in mass RNAi assays.
23	K09E3.7	K09E3.7	n/a	chrX 17,132,904	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000048720
24	ZC513.5	ZC513.5	n/a	chrV 8,037,288	contains similarity to Pfam domain PF03901 Alg9-like mannosyltransferase family contains similarity to Interpro domain IPR005599 (Alg9-like mannosyltransferase)
25	sel-12	F35H12.3	n/a	chrX 917,054	sel-12 encodes a transmembrane domain protein orthologous to presenilins; during gonadal, germline, and vulval development, sel-12 functions, within receiving cells, to positively regulate lin-12 and glp-1 Notch-like signaling pathways; sel-12 presenilin activity and/or levels are likely regulated by the SET/NAP protein sub-family member encoded by spr-2, as mutations in sel-12 are suppressed by mutations in spr-2; spr-2 regulation of sel-12 occurs in a hop-1 presenilin dependent manner.
26	F02H6.2	F02H6.2	n/a	chrIV 14,197,604	contains similarity to Trichomonas vaginalis G3 Putative uncharacterized protein.; TR:A2F8N8
27	T08D2.8	T08D2.8	n/a	chrX 196,174	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
28	W06E11.1	W06E11.1	n/a	chrIII 643,797	contains similarity to Pfam domain PF04801 Sin-like protein conserved region contains similarity to Interpro domain IPR006886 (Sin-like protein conserved region)
29	srh-141	T08G3.5	n/a	chrV 16,444,803	C. elegans SRH-141 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	T10B5.8	T10B5.8	n/a	chrV 1,843,425	contains similarity to Pfam domain PF00724 NADH:flavin oxidoreductase / NADH oxidase family contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001155 (NADH:flavin oxidoreductase/NADH oxidase, N-terminal)
31	lsm-7	ZK593.7	n/a	chrIV 10,933,821	C. elegans LSM-7 protein; contains similarity to Pfam domain PF01423 LSM domain contains similarity to Interpro domains IPR001163 (Like-Sm ribonucleoprotein, core), IPR006649 (Like-Sm ribonucleoprotein, eukaryotic and archaea-type, core), IPR010920 (Like-Sm ribonucleoprotein-related, core), IPR017132 (U6 snRNA-associated Sm-like protein LSm7)
32	srj-11	T28A11.12	n/a	chrV 3,242,029	C. elegans SRJ-11 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	K11B4.2	K11B4.2	n/a	chrI 14,798,156	contains similarity to Tetraodon nigroviridis UPF0402 protein.; SW:Q4S3C1
34	str-19	T23D5.7	n/a	chrV 15,743,832	C. elegans STR-19 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	R107.2	R107.2	n/a	chrIII 9,044,850	contains similarity to Pfam domain PF01256 Carbohydrate kinase contains similarity to Interpro domain IPR000631 (Carbohydrate kinase)
36	E02H9.6	E02H9.6	n/a	chrIII 2,439,204	contains similarity to Interpro domain IPR000694 (Proline-rich region)
37	Y40H7A.3	Y40H7A.3	n/a	chrIV 15,162,987	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
38	bath-19	F59H6.1	n/a	chrII 2,037,587	C. elegans BATH-19 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) (3), PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
39	ekl-5	Y26E6A.1	n/a	chrX 13,915,941	C. elegans EKL-5 protein; contains similarity to Interpro domains IPR001579 (Glycoside hydrolase, chitinase active site), IPR006642 (Zinc finger, Rad18-type putative)
40	T24E12.2	T24E12.2	n/a	chrII 3,783,547
41	clec-50	W04E12.8	n/a	chrV 19,749,271	C. elegans CLEC-50 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR000480 (Glutelin), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
42	D1007.4	D1007.4	n/a	chrI 4,580,304	contains similarity to Homo sapiens Gem-associated protein 6; ENSEMBL:ENSP00000281950
43	prg-2	C01G5.2	n/a	chrIV 6,528,248	C. elegans PRG-2 protein; contains similarity to Pfam domains PF02171 (Piwi domain) , PF02170 (PAZ domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
44	glb-7	C23H5.2	n/a	chrIV 2,124,416	glb-7 encodes a globin with no obvious function in mass RNAi assays.
45	K08H2.3	K08H2.3	n/a	chrX 13,237,815	contains similarity to Rattus norvegicus Inositol 1,4,5-trisphosphate 3-kinase C.; TR:Q80ZG2
46	C06A8.2	C06A8.2	n/a	chrII 7,780,233	contains similarity to Homo sapiens snRNA-activating protein complex subunit 1; ENSEMBL:ENSP00000216294
47	K12H4.2	K12H4.2	n/a	chrIII 8,047,973	contains similarity to Pfam domain PF02410 Domain of unknown function DUF143 contains similarity to Interpro domain IPR004394 (Iojap-related protein)
48	F56D6.6	F56D6.6	n/a	chrIV 3,904,376
49	srsx-22	F38E1.8	n/a	chrV 8,352,357	C. elegans SRSX-22 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
50	cyp-14A3	K09A11.4	n/a	chrX 13,272,959	C. elegans CYP-14A3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)