UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y37D8A.2	Y37D8A.2	0	chrIII 12,822,776	contains similarity to Pfam domain PF04916 Phospholipase B contains similarity to Interpro domains IPR007000 (Laminin A), IPR013032 (EGF-like region, conserved site)
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	F28F5.4	F28F5.4	n/a	chrIII 6,816,698
4	ttll-15	K07C5.7	n/a	chrV 10,359,962	ttll-15 encodes a putative tubulin polyaminoacid ligase orthologous to Drosophila melanogaster CG4089 and Tetrahymena thermophila TTLL15; TTLL-15 has no obvious function in mass RNAi assays.
5	M02D8.1	M02D8.1	n/a	chrX 8,765,033	contains similarity to Pfam domain PF07679 Immunoglobulin I-set domain contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR013098 (Immunoglobulin I-set), IPR013783 (Immunoglobulin-like fold), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype)
6	nspc-13	F42F12.6	n/a	chrX 12,357,636	C. elegans NSPC-13 protein ;
7	bath-46	T07H3.2	n/a	chrII 1,598,755	C. elegans BATH-46 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
8	clec-51	B0218.6	n/a	chrIV 8,162,862	C. elegans CLEC-51 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR003990 (Pancreatitis-associated protein), IPR001304 (C-type lectin), IPR002352 (Eosinophil major basic protein)
9	R05D3.6	R05D3.6	n/a	chrIII 8,350,531	R05D3.6 encodes the epsilon subunit of the soluble, catalytic F1 portion of ATP synthase (mitochondrial respiratory chain [MRC] complex V); RNAi experiments indicate that loss of R05D3.6 activity has minor effects on growth rate.
10	T28D9.7	T28D9.7	n/a	chrII 6,478,174	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
11	F16H6.10	F16H6.10	n/a	chrV 18,223,587	contains similarity to Haemophilus influenzae Putative protease HI0419 (EC 3.4.-.-).; SW:YEGQ_HAEIN
12	K08D10.10	K08D10.10	n/a	chrIV 4,155,758
13	W03G11.3	W03G11.3	n/a	chrX 12,101,925	contains similarity to Pfam domain PF01120 Alpha-L-fucosidase contains similarity to Interpro domains IPR016286 (Alpha-L-fucosidase), IPR017853 (Glycoside hydrolase, catalytic core), IPR013781 (Glycoside hydrolase, subgroup, catalytic core), IPR000933 (Glycoside hydrolase, family 29 (alpha-L-fucosidase))
14	far-8	K02F3.3	n/a	chrIII 843,359	C. elegans FAR-8 protein ;
15	gsnl-1	K06A4.3	n/a	chrV 9,498,184	C. elegans GSNL-1 protein; contains similarity to Pfam domain PF00626 Gelsolin repeat contains similarity to Interpro domains IPR007122 (Gelsolin), IPR007123 (Gelsolin region)
16	F46F5.13	F46F5.13	n/a	chrII 803,511	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
17	H34I24.1	H34I24.1	n/a	chrIII 2,847,797
18	glb-13	F19H6.2	n/a	chrX 12,374,995	glb-13 encodes a globin with no obvious function in mass RNAi assays.
19	ctl-1	Y54G11A.6	n/a	chrII 14,304,828	ctl-1 encodes one of three C. elegans catalases; CTL-1 exhibits catalase activity in vitro, and thus likely functions in vivo as an antioxidant enzyme that protects cells from reactive oxygen species; ctl-1 activity contributes to the extended lifespan seen in daf-2 mutant animals; in addition, ctl-1 expression is negatively regulated by DAF-2-mediated insulin signaling; as CTL-1 does not possess a C-terminal peroxisomal targeting signal (PTS), it is predicted to be a cytosolic catalase.
20	F16G10.7	F16G10.7	n/a	chrII 2,379,927	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
21	ncr-1	F02E8.6	n/a	chrX 4,476,155	ncr-1 encodes a large transmembrane glycoprotein with a patched-like domain that is orthologous to human NPC1 (OMIM:257220, mutated in Niemann-Pick type C disease); NCR-1 and NPC1 are eukaryotic members of the resistance-nodulation-division (RND) family of membrane permeases, and have a putative sterol-sensing domain; by homology, NCR-1 is predicted to function in intracellular cholesterol and glycolipid trafficking; in C. elegans, NCR-1 is required for growth and survival in the absence of cholesterol, newly hatched ncr-1 mutant larvae grow poorly on cholesterol-free medium and die at the L1 or L2 stage; NCR-1 is also involved in negative regulation of dauer formation, being required redundantly with NCR-2, a second C. elegans NPC1-like protein, for preventing constitutive dauer formation; dauer formation in ncr-1; ncr-2 double mutants is suppressed by mutations in daf-12, which encodes a steroid hormone receptor, and by overexpression of daf-9, which encodes a cytochrome P450, suggesting that NCR-1 and NCR-2 may function to transport a sterol precursor that is metabolized by DAF-9 to then serve as the DAF-12 ligand.
22	ZK652.8	ZK652.8	n/a	chrIII 7,842,935
23	srh-264	T06E6.8	n/a	chrV 15,414,724	C. elegans SRH-264 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	K02C4.2	K02C4.2	n/a	chrII 8,076,226	contains similarity to Brugia pahangi Alt-1 protein.; TR:O96781
25	rab-6.2	T25G12.4	n/a	chrX 17,223,409	rab-6.2 encodes a small, monomeric Rab GTPase that is most closely related to the Drosophila and mammalian Rab6 GTPases; by homology, RAB-6.2 is predicted to function in the regulation of intracellular membrane trafficking; RNAi experiments indicate that rab-6.2 is required redundantly with rab-6.1 for normal embryonic development and reproduction.
26	grsp-2	T28C6.1	n/a	chrIV 8,817,412	C. elegans GRSP-2 protein; contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR000817 (Prion protein), IPR008119 (Dense granule Gra6 protein), IPR001151 (GPR6 orphan receptor)
27	cdh-7	R05H10.6	n/a	chrII 14,846,930	cdh-7 encodes a protein that contains a cadherin domain.
28	fbxa-31	ZC47.5	n/a	chrIII 1,270,493	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
29	F01G12.6	F01G12.6	n/a	chrX 16,401,117	contains similarity to Drosophila melanogaster Flybase gene name is CG11727-PA;; FLYBASE:CG11727
30	apm-1	F55A12.7	n/a	chrI 5,343,455	The apm-1 gene encodes an adaptin: specifically, it encodes an ortholog of the mu1-II subunit of adaptor protein complex 1 (AP-1).
31	T01D3.1	T01D3.1	n/a	chrV 13,691,269	contains similarity to Pfam domain PF00008 (EGF-like domain)
32	F21F8.6	F21F8.6	n/a	chrV 8,266,564
33	lst-2	R160.7	n/a	chrX 4,380,673	C. elegans LST-2 protein; contains similarity to Pfam domain PF01363 FYVE zinc finger contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
34	Y17G7B.11	Y17G7B.11	n/a	chrII 12,061,387	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
35	F48F5.2	F48F5.2	n/a	chrV 20,441,470	contains similarity to Homo sapiens Intestinal mucin; TR:O43420
36	str-146	F58G4.6	n/a	chrV 8,094,425	C. elegans STR-146 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	tli-1	F25H2.1	n/a	chrI 10,536,634	C. elegans TLI-1 protein; contains similarity to Pfam domains PF00168 (C2 domain) , PF02845 (CUE domain) contains similarity to Interpro domains IPR003892 (Ubiquitin system component Cue), IPR009060 (UBA-like), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
38	C18B2.3	C18B2.3	n/a	chrX 3,603,031
39	K08D8.3	K08D8.3	n/a	chrIV 12,905,268	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
40	fbxa-150	Y38H6C.11	n/a	chrV 20,518,929	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
41	F09B9.1	F09B9.1	n/a	chrX 10,140,628	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
42	bre-3	B0464.4	n/a	chrIII 9,471,846	bre-3 encodes a protein similar to beta-glycosyltransferases from bacteria that is required for the toxicity of Bacillus thuringiensis Cry5B; BRE-3 may act in a pathway with bre-5 and is expressed and functions in the gut epithelium.
43	pqn-24	D1007.14	n/a	chrI 4,564,993	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
44	his-16	ZK131.10	n/a	chrII 13,817,860	his-16 encodes an H2A histone; his-16 is contained within the histone gene cluster HIS3.
45	tag-198	F09G8.2	n/a	chrIII 8,269,509	C. elegans TAG-198 protein; contains similarity to Pfam domain PF03265 Deoxyribonuclease II contains similarity to Interpro domain IPR004947 (Deoxyribonuclease II)
46	T10E10.4	T10E10.4	n/a	chrX 6,318,637	T10E10.4 encodes a large (966-residue) protein, predicted to be secreted, with two N-terminal chitin-binding peritrophin-A domains followed by 14 cysteine-rich domains and one C-terminal EB module; the general organization of T10E10.4 protein resembles that of K04H4.2; T10E10.4 has no obvious function in mass RNAi assays but, like CEJ-1 and CPG-2, might participate in chitin synthesis.
47	ubc-23	C28G1.1	n/a	chrX 8,846,276	ubc-23 encodes a predicted conjugating enzyme (UBCs/E2s) of the ubiquitin-conjugation system; expressed in larvae and adults in cells around the pharynx and in intestinal cells.
48	W02B12.9	W02B12.9	n/a	chrII 11,470,937	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
49	F45E1.5	F45E1.5	n/a	chrX 7,978,560	contains similarity to Interpro domain IPR000834 (Peptidase M14, carboxypeptidase A)
50	pmp-2	C44B7.9	n/a	chrII 6,885,843	C. elegans PMP-2 protein; contains similarity to Pfam domains PF06472 (ABC transporter transmembrane region 2) , PF00005 (ABC transporter) contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR011527 (ABC transporter, transmembrane region, type 1), IPR010509 (ABC transporter, N-terminal), IPR003593 (AAA+ ATPase, core), IPR005283 (Peroxysomal long chain fatty acyl transporter)