UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y18D10A.23	Y18D10A.23	0	chrI 12,868,302	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR013057 (Amino acid transporter, transmembrane), IPR006634 (TRAM, LAG1 and CLN8 homology)
2	col-44	F54B11.2	n/a	chrX 13,591,900	col-44 encodes a cuticle collagen.
3	Y66H1A.5	Y66H1A.5	n/a	chrIV 428,660
4	col-51	T28F2.8	n/a	chrI 3,654,613	col-51 encodes a cuticle collagen.
5	far-6	W02A2.2	n/a	chrIV 13,328,799	C. elegans FAR-6 protein; contains similarity to Pfam domain PF05823 Nematode fatty acid retinoid binding protein (Gp-FAR-1) contains similarity to Interpro domain IPR008632 (Nematode fatty acid retinoid binding)
6	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
7	T12D8.5	T12D8.5	n/a	chrIII 13,626,155	contains similarity to Treponema pallidum Nuclease sbcCD subunit C.; SW:SBCC_TREPA
8	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
9	clec-148	F40G9.10	n/a	chrIII 175,220	C. elegans CLEC-148 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR002352 (Eosinophil major basic protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
10	zig-2	F42F12.2	n/a	chrX 12,340,922	zig-2 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-2::gfp reporter fusion is expressed in the PVT interneuron and weakly in 4-6 additional head neurons.
11	srz-54	Y102A5C.25	n/a	chrV 16,981,243	C. elegans SRZ-54 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
12	col-85	T21B4.2	n/a	chrII 12,494,362	C. elegans COL-85 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat), IPR013286 (Annexin, type VII)
13	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
14	D1005.5	D1005.5	n/a	chrX 1,471,940
15	F08F1.3	F08F1.3	n/a	chrX 8,430,035
16	inx-9	ZK792.3	n/a	chrIV 11,677,349	inx-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; although the precise role of INX-9 in C. elegans development and/or behavior is not yet known, INX-9 may play a role in gonad or germline development, as INX-9 expression is detected solely in the sheath cells of the somatic gonad and particularly, the sheath cells in contact with proximal oocytes.
17	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
18	Y57G11C.20	Y57G11C.20	n/a	chrIV 14,844,297	contains similarity to Interpro domain IPR000003 ()
19	ilys-3	C45G7.3	n/a	chrIV 2,464,939	C. elegans ILYS-3 protein; contains similarity to Pfam domain PF05497 Destabilase contains similarity to Interpro domain IPR008597 (Destabilase)
20	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
21	T04A11.1	T04A11.1	n/a	chrIV 12,476,146	contains similarity to Pfam domain PF02567 Phenazine biosynthesis-like protein contains similarity to Interpro domain IPR003719 (Phenazine biosynthesis PhzC/PhzF protein)
22	F36F2.2	F36F2.2	n/a	chrI 9,017,387	contains similarity to Procambarus clarkii I-connectin.; TR:Q95YM2
23	C24F3.2	C24F3.2	n/a	chrIV 10,223,062	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016278 (Tyrosine protein phosphatase, dual specificity, 12), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
24	hgo-1	W06D4.1	n/a	chrI 9,052,445	hgo-1 encodes a putative homogentisate 1,2-dioxygenase, orthologous to human HGD (OMIM:607474, mutated in alkaptonuria), that is required for normal resistance to hypertonic stress; HGO-1 is expressed in larval and adult hypodermis and intestine, and in larval pharynx; HGO-1 is required for the tyrosinemic phenotype of K10C2.4(RNAi) animals.
25	nnt-1	C15H9.1	n/a	chrX 6,124,888	nnt-1 encodes a proton-pumping nicotinamide nucleotide transhydrogenase predicted to be mitochondrial.
26	tyr-1	C02C2.1	n/a	chrIII 7,875,371	C02C2.1 encodes a tyrosinase homolog with a glutamine/asparagine-rich domain.
27	col-114	D2024.8	n/a	chrIV 7,246,056	C. elegans COL-114 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
28	glc-1	F11A5.10	n/a	chrV 16,220,736	glc-1 encodes the alpha subunit of a glutamate-gated chloride channel and forms a functional channel in Xenopus oocytes; mutations genetically interact with avr-14 and avr-15 mutations such that triple mutants exhibit high level resistance to ivermectin.
29	sms-2	F53H8.4	n/a	chrX 946,855	C. elegans SMS-2 protein ; contains similarity to Aedes aegypti Spingomyelin synthetase.; TR:Q17C34
30	F35C8.5	F35C8.5	n/a	chrX 5,366,661	contains similarity to Pfam domain PF01598 contains similarity to Interpro domain IPR006088 (Sterol desaturase)
31	lact-2	ZK945.1	n/a	chrII 10,096,751	lact-2 encodes a beta-lactamase domain-containing protein that contains a predicted transmembrane domain in its N terminus.
32	F26G1.3	F26G1.3	n/a	chrII 4,759,013	F26G1.3 encodes a protein containing a transthyretin-like domain; the product of F26G1.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known.
33	C06A5.6	C06A5.6	n/a	chrI 5,984,551
34	srp-6	C03G6.19	n/a	chrV 7,385,156	srp-6 encodes a functional serpin (serine protease inhibitor)
35	ard-1	F01G4.2	n/a	chrIV 11,132,448	ard-1 encodes a homolog of mammalian 3-hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD) that is predicted to be mitochondrial.
36	btb-21	F47C10.2	n/a	chrV 3,850,930	C. elegans BTB-21 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
37	T12B3.3	T12B3.3	n/a	chrIV 7,375,883	contains similarity to Pfam domain PF03009 Glycerophosphoryl diester phosphodiesterase family contains similarity to Interpro domain IPR004129 (Glycerophosphoryl diester phosphodiesterase)
38	spp-1	T07C4.4	n/a	chrIII 10,355,287	spp-1 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-1 is predicted to function as a lipid-binding protein with cytotoxic, pore-forming activity, and in vitro, does exhibit antibacterial activity; loss of SPP-1 function via RNA-mediated interference (RNAi) does not, however, result in any abnormalities.
39	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
40	C33H5.2	C33H5.2	n/a	chrIV 7,806,489	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
41	Y76A2B.5	Y76A2B.5	n/a	chrIII 13,547,827	contains similarity to Danio rerio Zgc:91819 protein.; TR:Q6GMH4
42	ttr-15	T07C4.5	n/a	chrIII 10,338,481	C. elegans TTR-15 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
43	Y51B9A.9	Y51B9A.9	n/a	chrII 9,396,480	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR008351 (JNK MAP kinase), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
44	ZK337.2	ZK337.2	n/a	chrI 14,977,996	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
45	F15E6.4	F15E6.4	n/a	chrIV 4,291,666
46	old-2	ZK938.5	n/a	chrII 9,848,462	old-2 encodes a transmembrane protein tyrosine kinase (also known as 'kin-28') that affects mean and maximum life span with multiple paralogs in C. elegans; the expression of old-2 was experimentally verified by RT-PCR.
47	col-43	ZC513.8	n/a	chrV 8,050,298	col-43 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens.
48	M176.8	M176.8	n/a	chrII 9,437,409	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
49	acl-1	F59F4.4	n/a	chrX 15,850,758	acl-1 encodes a 1-acyl-sn-glycerol-3-phosphate acyltransferase; ACL-1 is predicted to be a membrane protein that plays a role in phospholipid biosynthesis, but as loss of acl-1 activity via large-scale RNAi experiments results in no obvious defects, the precise role of ACL-1 in C. elegans development and/or behavior is not yet known.
50	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)