UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y106G6H.16	Y106G6H.16	1e-77	chrI 10,475,167	contains similarity to Salmonella typhimurium Putative cytoplasmic protein (STMF1.42 protein).; TR:Q9L9K2
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	mdt-22	ZK970.3	n/a	chrII 10,301,446	C. elegans MDT-22 protein; contains similarity to Pfam domain PF06179 Surfeit locus protein 5 contains similarity to Interpro domain IPR009332 (Surfeit locus 5)
4	C09H10.5	C09H10.5	n/a	chrII 11,101,400	contains similarity to Mus musculus Similar to serine/threonine kinase 24 (Ste20, yeast homolog).; TR:Q99KH8
5	F53B7.4	F53B7.4	n/a	chrV 11,001,724	contains similarity to Interpro domains IPR004090 (Chemotaxis methyl-accepting receptor), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
6	F35E8.10	F35E8.10	n/a	chrV 15,919,877	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
7	lgg-3	B0336.8	n/a	chrIII 5,697,730	lgg-3 encodes a hydrophilic protein that is orthologous to Saccharomyces cerevisiae autophagy protein Apg12p; by homology, LGG-3 is predicted to function as a modifier protein required for a protein conjugation system essential for autophagy; in the context of this conjugation system, LGG-3 is predicted to interact with Apg7p and Apg5p homologs (encoded by M7.5 and Y71G12B.12a, respectively) to effect bulk degradation of cytoplasmic components under conditions of starvation or cellular remodeling; free LGG-3 is predicted to localize to the cytoplasm, while LGG-3 conjugated to the Apg5p homolog is predicted to associate with membrane compartments; loss of lgg-3 activity via large-scale RNAi screens results in no obvious developmental or behavioral abnormalities.
8	C16C4.1	C16C4.1	n/a	chrII 1,894,512
9	C30G12.3	C30G12.3	n/a	chrII 7,275,917
10	srp-2	C05E4.1	n/a	chrV 763,702	srp-2 encodes an ovalbumin-like serpin (ov-serpin) member of the serine protease inhibitor superfamily that is orthologous to human NEUROSERPIN (OMIM:602445, mutated in familial encephalopathy with neuroserpin inclusion bodies); SRP-2 is predicted to function as a suicide substrate that inhibits the proteolytic activity of serine proteases, and in vitro, recombinant SRP-2 is able to inhibit granzyme B activity; however, as loss of srp-2 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of SRP-2 in C. elegans development and/or behavior is not yet known; srp-2 expression is detected in hypodermal cells, particularly in the lateral seam cells.
11	gcy-13	F23H12.6	n/a	chrV 12,366,622	gcy-13 encodes a predicted guanylate cyclase.
12	nhr-192	F57A8.5	n/a	chrV 10,069,976	C. elegans NHR-192 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
13	ZK1240.4	ZK1240.4	n/a	chrII 2,315,354
14	B0334.4	B0334.4	n/a	chrII 11,496,096	contains similarity to Pfam domain PF04707 PRELI-like family contains similarity to Interpro domain IPR006797 (MSF1)
15	btb-10	K02E7.9	n/a	chrII 1,060,263	C. elegans BTB-10 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
16	Y75B8A.18	Y75B8A.18	n/a	chrIII 12,226,253	contains similarity to Homo sapiens Splice isoform 1 of Q03001 Bullous pemphigoid antigen 1 isoforms 1/2/3/4/5/8; ENSEMBL:ENSP00000281662
17	fbxb-67	F49B2.2	n/a	chrI 14,297,764	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
18	2L52.1	2L52.1	n/a	chrII 3,265	2L52.1 encodes a protein with sequence similarity to GLI-family zinc-finger transcription factors; deletion mutations in 2L52.1 are reported to be homozygous viable.
19	sdz-2	C08A9.7	n/a	chrX 17,099,848	C. elegans SDZ-2 protein; contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
20	fbxb-35	F07E5.2	n/a	chrII 2,052,208	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
21	C08H9.7	C08H9.7	n/a	chrII 9,860,547	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
22	clec-12	T27F6.2	n/a	chrI 12,477,625	C. elegans CLEC-12 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	C50B6.1	C50B6.1	n/a	chrV 13,308,835	contains similarity to Synechocystis sp Hypothetical protein slr1813.; TR:P73698
24	W06D11.1	W06D11.1	n/a	chrX 12,294,462
25	C13F10.5	C13F10.5	n/a	chrV 7,217,043	contains similarity to Homo sapiens Isoform 2 of Uncharacterized protein C6orf64; ENSEMBL:ENSP00000362346
26	ZK1307.2	ZK1307.2	n/a	chrII 9,653,433	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q8T1G2
27	srw-48	F26D2.9	n/a	chrV 16,421,858	C. elegans SRW-48 protein ; contains similarity to Homo sapiens Uncharacterized protein MPHOSPH1; ENSEMBL:ENSP00000377830
28	C56E6.2	C56E6.2	n/a	chrII 6,525,580	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras), IPR006036 (Potassium uptake protein TrkA), IPR002078 (RNA polymerase sigma factor 54, interaction)
29	F14B8.2	F14B8.2	n/a	chrX 6,904,852
30	tag-40	R02C2.3	n/a	chrV 249,183	C. elegans TAG-40 protein; contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
31	F26F2.2	F26F2.2	n/a	chrV 20,559,052	contains similarity to Saccharomyces cerevisiae Global transcription activator that acts in complex with Snf2p, Snf5p, Snf6p, and Swi3p to assist gene-specific activators; involved in the regulation of expression of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; SGD:YPL016W
32	T22C8.4	T22C8.4	n/a	chrII 8,623,075	contains similarity to Interpro domains IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
33	T20F10.4	T20F10.4	n/a	chrI 10,305,153	contains similarity to Streptococcus mutans Putative 16S rRNA processing protein.; TR:Q8DUN7
34	F48F7.3	F48F7.3	n/a	chrX 13,964,989	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
35	B0416.4	B0416.4	n/a	chrX 9,279,335	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR000533 (Tropomyosin), IPR001841 (Zinc finger, RING-type), IPR000956 (Stathmin), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
36	W07A12.6	W07A12.6	n/a	chrII 9,158,925	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
37	srx-48	T26H8.2	n/a	chrV 15,303,024	C. elegans SRX-48 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
38	ced-8	F08F1.5	n/a	chrX 8,415,405	The ced-8 gene encodes a homolog of the human putative membrane transporter XK; ced-8 is required for apoptosis to occur with normal speed during embryonic development.
39	C44B9.3	C44B9.3	n/a	chrIII 10,879,120	contains similarity to Trypanosoma cruzi Mucin-like protein.; TR:O61047
40	ZK686.1	ZK686.1	n/a	chrIII 7,773,406	contains similarity to Interpro domain IPR004038 (Ribosomal protein L7Ae/L30e/S12e/Gadd45)
41	his-8	F45F2.12	n/a	chrV 8,532,878	his-8 encodes an H2B histone; his-8 is contained within the histone gene cluster HIS2.
42	M110.3	M110.3	n/a	chrII 8,215,496	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
43	C50F4.4	C50F4.4	n/a	chrV 9,537,163	contains similarity to Streptomyces coelicolor Hypothetical protein SCO3733.; TR:Q9L0X1
44	B0416.2	B0416.2	n/a	chrX 9,299,586
45	mnm-2	C10A4.8	n/a	chrX 7,423,795	C. elegans MNM-2 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
46	grd-7	F46H5.6	n/a	chrX 7,269,472	grd-7 encodes a hedgehog-like protein, with an N-terminal DUF271 domain, a central low-complexity proline-rich domain, and a C-terminal Ground (Grd) domain; GRD-7 is expressed in three to four posterior DA motor neurons of the ventral nerve cord; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-7 is weakly required for normal molting; GRD-7 is also required for normal growth to full size, cuticle adhesion, locomotion, and vulval morphogenesis; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
47	gur-5	ZK622.2	n/a	chrII 5,287,091	C. elegans GUR-5 protein ;
48	B0281.6	B0281.6	n/a	chrII 2,301,816	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation), IPR000210 (BTB/POZ-like)
49	F47B7.3	F47B7.3	n/a	chrX 3,763,711	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
50	lgc-9	C04C3.2	n/a	chrIV 3,417,455	C. elegans LGC-9 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)