UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	Y102E9.3	Y102E9.3	5e-65	chrIII 6,734,194
2	old-1	C08H9.5	n/a	chrII 9,867,626	old-1 encodes a receptor protein tyrosine kinase; old-1 activity is required for stress resistance and regulation of adult lifespan: old-1 mRNA expression is upregulated in response to stress and in daf-2 and age-1 mutant backgrounds; likewise, overexpression of old-1 in wild-type animals extends lifespan and increases resistance to heat and UV irradiation; an OLD-1::GFP fusion protein is expressed in the anterior region of worms, in neuronal, hypodermal, and pharyngeal tissues, as well as in the proximal region of the male gonad; expression is visible in young adults and appears to increase as animals age and in response to heat, starvation, or UV irradiation.
3	ZK380.2	ZK380.2	n/a	chrX 1,633,167	contains similarity to Interpro domain IPR011072 (HR1 rho-binding repeat)
4	F16G10.1	F16G10.1	n/a	chrII 2,402,918	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
5	F56C3.7	F56C3.7	n/a	chrX 1,370,660
6	F53G12.11	F53G12.11	n/a	chrI 145,479	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)
7	math-31	F52C6.6	n/a	chrII 1,912,654	C. elegans MATH-31 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
8	nhr-268	K06B4.6	n/a	chrV 15,690,903	C. elegans NHR-268 protein
9	gst-30	ZK546.11	n/a	chrII 4,934,462	C. elegans GST-30 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
10	ZK218.4	ZK218.4	n/a	chrV 17,100,011	contains similarity to Interpro domain IPR000434 (Polycystic kidney disease type 1 protein)
11	C03E10.1	C03E10.1	n/a	chrV 11,291,855	contains similarity to Anopheles quadrimaculatus NADH-ubiquinone oxidoreductase chain 4 (EC 1.6.5.3).; SW:NU4M_ANOQU
12	H25K10.4	H25K10.4	n/a	chrIV 16,226,802	contains similarity to Pseudomonas putida Hypothetical protein.; TR:Q8VMP3
13	F44G3.10	F44G3.10	n/a	chrV 16,139,209	F44G3.10 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F44G3.10 is worm-specific, with obvious homologs only in C. elegans; F44G3.10 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
14	clec-20	T07H3.5	n/a	chrII 1,594,363	C. elegans CLEC-20 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
15	srw-143	H27D07.3	n/a	chrV 2,940,553	C. elegans SRW-143 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
16	str-236	K02H11.3	n/a	chrV 1,527,292	C. elegans STR-236 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003567 (Cytochrome c-type biogenesis protein)
17	K02F3.7	K02F3.7	n/a	chrIII 836,776
18	str-257	C01B4.1	n/a	chrV 2,519,650	C. elegans STR-257 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	F21H12.2	F21H12.2	n/a	chrII 6,088,063
20	nhr-150	C06B8.1	n/a	chrV 15,480,433	C. elegans NHR-150 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
21	gcy-23	T26C12.4	n/a	chrIV 3,286,107	gcy-23 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-18, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-23 functions redundantly with gcy-8 and gcy-18, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, loss of gcy-23 activity via RNAi results in lifespan extension; GCY-23 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
22	C27F2.1	C27F2.1	n/a	chrIII 4,989,295	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
23	F47B7.5	F47B7.5	n/a	chrX 3,768,291	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
24	Y26D4A.5	Y26D4A.5	n/a	chrI 13,076,809	contains similarity to Staphylococcus aureus Hypothetical protein SAV2385 (Hypothetical protein MW2305).; TR:Q99RP4
25	srxa-7	C31A11.6	n/a	chrV 16,308,625	C. elegans SRXA-7 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
26	glr-3	K10D3.1	n/a	chrI 7,119,675	glr-3 encodes a protein that contains a ligand-gated ion channel domain and a receptor family ligand binding domain with similarity to kainate-selective ionotropic glutamate receptor 2 (human GRIK2); expressed in the RIA neuron.
27	srt-59	C18H7.8	n/a	chrIV 601,062	C. elegans SRT-59 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR006058 (2Fe-2S ferredoxin, iron-sulphur binding site), IPR007087 (Zinc finger, C2H2-type)
28	srbc-23	C45H4.9	n/a	chrV 2,154,343	C. elegans SRBC-23 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
29	F22D6.8	F22D6.8	n/a	chrI 7,099,204
30	nhr-190	F48G7.11	n/a	chrV 641,845	C. elegans NHR-190 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
31	srw-124	C44C3.1	n/a	chrV 2,977,215	C. elegans SRW-124 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
32	F16G10.8	F16G10.8	n/a	chrII 2,382,692	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
33	fkh-5	F26A1.2	n/a	chrIII 4,845,567	fkh-5 encodes a member of the forkhead domain transcription factor family.
34	C04B4.6	C04B4.6	n/a	chrX 12,275,348	contains similarity to Corynebacterium efficiens Putative alanyl-tRNA synthetase.; TR:Q8FT23
35	F10A3.11	F10A3.11	n/a	chrV 16,163,213	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
36	srw-4	F37B4.8	n/a	chrV 2,887,985	C. elegans SRW-4 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
37	str-38	T23D5.2	n/a	chrV 15,731,518	C. elegans STR-38 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	C24A8.5	C24A8.5	n/a	chrX 4,328,634
39	F20E11.5	F20E11.5	n/a	chrV 17,461,590	contains similarity to Pfam domain PF03436 Domain of unknown function (DUF281) contains similarity to Interpro domain IPR005098 (Protein of unknown function DUF281)
40	srj-6	F31F4.8	n/a	chrV 653,904	C. elegans SRJ-6 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	nkat-1	F28H6.3	n/a	chrX 14,139,007	nkat-1 encodes kynurenine aminotransferase III, an ortholog of mammalian KAT3; nkat-1(RNAi) animals have no obvious phenotype.
42	C06B3.7	C06B3.7	n/a	chrV 13,910,615	contains similarity to Streptococcus agalactiae Tn5252, relaxase.; TR:Q8DZ67
43	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
44	sri-37	D2062.2	n/a	chrII 2,630,401	C. elegans SRI-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	srh-102	F40D4.11	n/a	chrV 17,164,173	C. elegans SRH-102 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	srbc-8	C18B10.5	n/a	chrV 7,484,197	C. elegans SRBC-8 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
47	F54F2.6	F54F2.6	n/a	chrIII 8,800,500
48	Y39F10A.1	Y39F10A.1	n/a	chrII 776,047
49	F41E6.8	F41E6.8	n/a	chrV 8,600,475	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
50	R10E8.5	R10E8.5	n/a	chrV 18,255,890	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)