UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	clec-35	Y102A5B.2	0	chrV 16,853,143	C. elegans CLEC-35 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
2	T03G11.4	T03G11.4	n/a	chrX 5,167,050	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
3	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	W06D11.4	W06D11.4	n/a	chrX 12,302,364	contains similarity to Pfam domain PF08123 Histone methylation protein DOT1 contains similarity to Interpro domain IPR013110 (Histone methylation DOT1)
5	W06E11.4	W06E11.4	n/a	chrIII 637,463	W06E11.4 encodes an ortholog of human SBDS (OMIM:607444, mutated in Shwachman-Bodian-Diamond syndrome) and S. cerevisiae SDO1; by homology, W06E11.4 is predicted to be a nucleolar protein that may be required for normal processing of rRNA; WS06E11.4 shares an operon with tag-266 and T19C3.7.
6	srx-38	C03A7.5	n/a	chrV 5,154,771	C. elegans SRX-38 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR013305 (ABC transporter, ABCB2), IPR000276 (GPCR, rhodopsin-like)
7	W03G9.3	W03G9.3	n/a	chrI 4,960,459
8	C17F3.1	C17F3.1	n/a	chrI 6,669,389
9	srbc-70	F30B5.6	n/a	chrIV 4,227,430	C. elegans SRBC-70 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
10	C25F6.6	C25F6.6	n/a	chrX 5,450,509
11	ggr-3	F09C12.1	n/a	chrII 5,131,702	ggr-3 encodes a predicted member of the GABA/ glycine receptor family of ligand-gated chloride channels; expressed in the AVA, AVB, SMDD, DVA, SIAD, and in some other neurons of the nerve ring.
12	lin-59	T12F5.4	n/a	chrI 3,717,339	C. elegans LIN-59 protein; contains similarity to Pfam domains PF01426 (BAH domain) , PF00628 (PHD-finger) , PF00856 (SET domain) contains similarity to Interpro domains IPR001214 (SET), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR001025 (Bromo adjacent region), IPR011011 (Zinc finger, FYVE/PHD-type), IPR006560 (AWS)
13	C50E3.5	C50E3.5	n/a	chrV 7,591,348	contains similarity to Interpro domain IPR008108 (Type III secretion system outer membrane, B protein)
14	C45E5.1	C45E5.1	n/a	chrIV 5,745,740	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR005834 (Haloacid dehalogenase-like hydrolase)
15	emb-30	F54C8.3	n/a	chrIII 9,438,172	emb-30 encodes an anaphase-promoting complex/cyclosome (APC/C) component orthologous to mammalian APC-4 and Schizosaccharomyces pombe Lid1; EMB-30 is required for the metaphase-to-anaphase transition during meiosis and mitosis, for establishing anterior-posterior polarity in the early embryo, and for proper localization of germline granules and the maternally provided PAR-2 and PAR-3 proteins.
16	lin-24	B0001.1	n/a	chrIV 12,132,269	lin-24 was identified in screens for mutations that result in altered vulval cell lineages; lin-24 is defined by two alleles, the first of which, a partially dominant mutation, generally results in vulvaless animals, while the second, a non-null amber mutation that is also partially dominant, results in wild-type animals when homozygous, but vulvaless animals when heterozygous with a wild-type allele; morphological examination of lin-24 animals indicates that some of the Pn.p cells that normally make up the vulva undergo inappropriate cell death that is dependent upon the ced-2, ced-5, and ced-10 engulfment genes, but not on the ced-3 and ced-4 killing genes; the precise molecular identity of lin-24 has not yet been reported.
17	F09E5.12	F09E5.12	n/a	chrII 5,368,494	contains similarity to Pfam domain PF05001 RNA polymerase Rpb1 C-terminal repeat
18	C47A4.1	C47A4.1	n/a	chrIV 13,716,255	contains similarity to Interpro domain IPR015609 (Molecular chaperone, heat shock protein, Hsp40, DnaJ)
19	srt-70	B0238.6	n/a	chrV 5,258,776	C. elegans SRT-70 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
20	C26B2.7	C26B2.7	n/a	chrIV 8,016,527
21	str-187	F26D10.8	n/a	chrIV 17,266,207	C. elegans STR-187 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000539 (Frizzled protein)
22	H08J19.1	H08J19.1	n/a	chrX 15,643,559	contains similarity to Homo sapiens formin-like 3 isoform 1; ENSEMBL:ENSP00000335655
23	sru-29	C50C10.2	n/a	chrV 9,812,012	C. elegans SRU-29 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
24	sra-31	C56C10.5	n/a	chrII 6,577,792	C. elegans SRA-31 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
25	B0432.9	B0432.9	n/a	chrII 283,160	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
26	F01G10.10	F01G10.10	n/a	chrIV 10,247,944	contains similarity to Pfam domains PF02886 (LBP / BPI / CETP family, C-terminal domain) , PF01273 (LBP / BPI / CETP family, N-terminal domain) contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
27	T09E11.1	T09E11.1	n/a	chrI 12,338,593	contains similarity to Pfam domain PF03360 Glycosyltransferase family 43 contains similarity to Interpro domain IPR005027 (Glycosyl transferase, family 43)
28	F41G4.5	F41G4.5	n/a	chrX 16,831,782
29	emb-27	F10B5.6	n/a	chrII 8,160,979	emb-27 encodes a tetratricopeptide repeat (TPR)-containing protein that is the C. elegans ortholog of the anaphase-promoting complex (APC) subunit APC-6 (CDC16); required maternally and paternally, EMB-27 activity is essential for proper execution of the metaphase-to-anaphase transition during meiosis (both oogenesis and spermatogenesis) and mitosis (during germline proliferation); EMB-27 activity is also critical for embryonic anterior-posterior (A-P) axis formation, production of the secreted eggshell, and normal vulval development; in establishing the embryonic A-P axis, EMB-27 likely acts upstream of the separin protease to ensure proper localization of PAR-3 and PAR-2 to the anterior and posterior cortices, respectively.
30	F19C6.5	F19C6.5	n/a	chrX 9,983,681	contains similarity to Homo sapiens Isoform 2 of Zinc transporter 8; HI:HIT000389038
31	B0280.10	B0280.10	n/a	chrIII 7,132,835
32	F15A8.6	F15A8.6	n/a	chrX 4,432,690	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
33	fpn-1.2	R09B5.4	n/a	chrV 1,463,421	R09B5.4 is orthologous to the human gene HYPOTHETICAL PROTEIN (SLC11A3; OMIM:604653), which when mutated leads to disease.
34	M04B2.2	M04B2.2	n/a	chrIV 11,529,284	contains similarity to Pfam domains PF01170 (Putative RNA methylase family UPF0020) , PF02926 (THUMP domain) contains similarity to Interpro domains IPR004114 (THUMP), IPR001091 (Site-specific DNA-methyltransferase (cytosine-N4-specific)), IPR000241 (Putative RNA methylase)
35	ckb-1	B0285.8	n/a	chrIII 4,366,386	ckb-1 encodes a putative choline kinase; CKB-1 through CKB-4 comprise a related group ('B') of choline kinases.
36	fbxa-22	T12B5.5	n/a	chrIII 939,140	C. elegans FBXA-22 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
37	T05E8.3	T05E8.3	n/a	chrI 5,475,882	The T05E8.3 gene encodes a divergent DEAH helicase that is (apparently) unique to Caenorhabditis; it has no well-characterized orthologs in the complete Drosophila or S. cerevisiae genomes, and no obvious orthologs in the draft human genome sequence either.
38	taf-9	T12D8.7	n/a	chrIII 13,624,992	C. elegans TAF-9 protein; contains similarity to Pfam domain PF02291 Transcription initiation factor IID, 31kD subunit contains similarity to Interpro domains IPR003162 (Transcription factor TAFII-31), IPR009072 (Histone-fold)
39	F26F2.3	F26F2.3	n/a	chrV 20,561,363	contains similarity to Saccharomyces cerevisiae Profilin synthetic lethal protein, has region of coiled-coil structure; subunit of the Exocyst complex--the Exocyst complex contains the gene products encoded by SEC3, SEC5, SEC6, SEC8, SEC10, SEC15 and EXO70 and is required for exocytosis; SGD:YER008C
40	ZK218.1	ZK218.1	n/a	chrV 17,092,954	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
41	nhr-168	C50B6.8	n/a	chrV 13,332,476	C. elegans NHR-168 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
42	C06A5.4	C06A5.4	n/a	chrI 5,981,191	contains similarity to Interpro domain IPR006578 (MADF)
43	haf-2	F43E2.4	n/a	chrII 7,354,944	haf-2 encodes a predicted transmembrane protein of the ATP-binding cassette (ABC) transporter superfamily; by homology, HAF-2 is proposed to function in ATP-dependent transport of molecules across plasma and intracellular membranes; however, as loss of HAF-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of HAF-2 in C. elegans development and/or behavior is not yet known.
44	C50F4.14	C50F4.14	n/a	chrV 9,548,707	The C50F4.14 gene encodes a putative GDP-fucose transporter orthologous to the human GDP-FUCOSE TRANSPORTER 1 gene (LAD II; OMIM:605881), which when mutated leads to congenital disorder of glycosylation, type IIc.
45	fbxa-81	T24C2.4	n/a	chrX 14,541,293	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
46	T01D1.5	T01D1.5	n/a	chrII 188,286
47	W08D2.5	W08D2.5	n/a	chrIV 9,821,001	contains similarity to Pfam domains PF00122 (E1-E2 ATPase) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR008250 (E1-E2 ATPase-associated region), IPR006544 (P-type ATPase of unknown pump specificity (type V)), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR000150 (Cof protein), IPR005834 (Haloacid dehalogenase-like hydrolase)
48	nhr-264	F14A5.1	n/a	chrIV 9,293,087	C. elegans NHR-264 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
49	F28C10.3	F28C10.3	n/a	chrX 533,819	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
50	ina-1	F54G8.3	n/a	chrIII 9,170,331	ina-1 encodes one of two C. elegans alpha integrin subunits; during development, ina-1 activity is required for migration of a number of cell types, including neurons, coelomocyte precursors, and the distal tip cells of the somatic gonad; in addition, ina-1 is required for axon fasciculation and morphogenesis of structures such as the head, pharynx, egg-laying apparatus, and male tail; INA-1 coimmunoprecipitates with the PAT-3 beta integrin subunit suggesting that, in vivo, INA-1 and PAT-3 function as a heterodimer to regulate cell migration and tissue morphogenesis; INA-1 is expressed in many tissues, including neurons, the gonad, and the pharyngeal basement membrane; expression begins during gastrulation and continues through to adulthood.