UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	W09H1.5	W09H1.5	0	chrII 13,186,582	contains similarity to Pfam domains PF00107 (Zinc-binding dehydrogenase) , PF08240 (Alcohol dehydrogenase GroES-like domain) contains similarity to Interpro domains IPR013149 (Alcohol dehydrogenase, zinc-binding), IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
2	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
3	his-26	ZK131.1	n/a	chrII 13,825,596	his-26 encodes an H4 histone.
4	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
5	T28C6.8	T28C6.8	n/a	chrIV 8,830,136	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
6	dhs-30	T25G12.7	n/a	chrX 17,233,193	dhs-30 encodes a member of the short-chain dehydrogenases/reductases family (SDR) homologous to HSD, which when mutated leads to cortisol 11-beta ketoreductase deficiency (OMIM:218030).
7	str-232	T10C6.1	n/a	chrV 16,015,103	C. elegans STR-232 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	col-33	F36A4.6	n/a	chrIV 4,264,264	col-33 encodes a predicted cuticular collagen; by homology, col-33 is predicted to play a role in cuticle biosynthesis and regulation of body size and morphogenesis; however, as loss of col-33 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of COL-33 in C. elegans development and/or behavior is not yet known.
9	his-14	ZK131.8	n/a	chrII 13,819,690	his-14 encodes an H4 histone.
10	asm-1	B0252.2	n/a	chrII 6,911,299	asm-1 encodes a protein similar to human acid sphingomyelinase (ASM) or sphingomyelin phosphodiesterase; the ASM-1 protein has a putative secretory signal peptide at the N-terminus, saposin-like and proline-rich domains and putative N-linked glycosylation sites; asm-1 shows phosphodiesterase activity when expressed in COS-7 cells; while mammalian ASM is detected as both intracellular and secreted forms, asm-1 was detected exclusively in the secreted form; northern blot analysis indicates that asm-1 is expressed at higher levels in the embryo compared with other stages.
11	C10G8.3	C10G8.3	n/a	chrV 5,313,573	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domain IPR002223 (Proteinase inhibitor I2, Kunitz metazoa)
12	C30H6.8	C30H6.8	n/a	chrIV 17,382,648	contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related)
13	Y106G6A.1	Y106G6A.1	n/a	chrI 9,937,203	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
14	srp-5	C03G6.18	n/a	chrV 7,382,647	srp-5 encodes an ovalbumin-like serpin (ov-serpin) member of the serine protease inhibitor superfamily; by homology, SRP-5 is predicted to function as a suicide substrate that inhibits the proteolytic activity of serine proteases; however, as loss of srp-5 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of SRP-5 in C. elegans development and/or behavior is not yet known.
15	T20D4.12	T20D4.12	n/a	chrV 3,397,421	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
16	F59F4.1	F59F4.1	n/a	chrX 15,836,220	contains similarity to Pfam domains PF01756 (Acyl-CoA oxidase) , PF02770 (Acyl-CoA dehydrogenase, middle domain) contains similarity to Interpro domains IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR012258 (Acyl-CoA oxidase), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR002655 (Acyl-CoA oxidase, C-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal)
17	his-9	ZK131.3	n/a	chrII 13,823,762	his-9 encodes an H3 histone; by homology, HIS-9 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-9 is a replication-dependent histone locus that resides in the HIS3 cluster on chromosome II.
18	K06A1.3	K06A1.3	n/a	chrII 6,442,625	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
19	srv-29	T13A10.6	n/a	chrIV 6,265,730	C. elegans SRV-29 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
20	F55A11.7	F55A11.7	n/a	chrV 11,785,988	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
21	tag-244	C34H4.3	n/a	chrIV 1,551,970	C. elegans TAG-244 protein; contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
22	F25E2.2	F25E2.2	n/a	chrX 808,888	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
23	fbxa-111	Y102A5C.14	n/a	chrV 16,949,135	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
24	grl-22	W03A5.3	n/a	chrIII 5,413,566	grl-22 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
25	msp-152	ZK546.6	n/a	chrII 4,933,207	msp-152 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
26	F48E8.3	F48E8.3	n/a	chrIII 5,462,687	contains similarity to Pfam domains PF00890 (FAD binding domain) , PF01266 (FAD dependent oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR010960 (Flavocytochrome c), IPR006076 (FAD dependent oxidoreductase), IPR003953 (Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal), IPR016040 (NAD(P)-binding)
27	C01H6.6	C01H6.6	n/a	chrI 7,223,298	C01H6.6 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C33D12.2, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C01H6.6 may participate in metal homoeostasis; C01H6.6, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C01H6.6 has no obvious function in RNAi assays.
28	C48E7.6	C48E7.6	n/a	chrI 6,244,688	contains similarity to Drosophila pseudoobscura GA10211-PA (Fragment).; TR:Q29MP8
29	C08H9.13	C08H9.13	n/a	chrII 9,870,236	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR003624 (Leukemia inhibitory factor), IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
30	lite-1	C14F11.3	n/a	chrX 6,228,375	C. elegans LITE-1 protein; contains similarity to Pfam domain PF08395 7tm Chemosensory receptor contains similarity to Interpro domains IPR009318 (Trehalose receptor), IPR013604 (7TM chemoreceptor)
31	T12B3.3	T12B3.3	n/a	chrIV 7,375,883	contains similarity to Pfam domain PF03009 Glycerophosphoryl diester phosphodiesterase family contains similarity to Interpro domain IPR004129 (Glycerophosphoryl diester phosphodiesterase)
32	cyp-35B3	K07C6.2	n/a	chrV 3,946,183	C. elegans CYP-35B3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
33	math-23	C46F9.2	n/a	chrII 1,903,365	The C46F9.2 gene encodes a protein closely similar to C46F9.3, which has a meprin-associated Traf homology (MATH) domain and may be involved in apoptosis.
34	Y37D8A.4	Y37D8A.4	n/a	chrIII 12,837,949	contains similarity to Pfam domain PF00017 SH2 domain contains similarity to Interpro domain IPR000980 (SH2 motif)
35	F31E9.3	F31E9.3	n/a	chrV 17,323,648	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
36	btb-4	F59H6.12	n/a	chrII 2,032,856	C. elegans BTB-4 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
37	ZC15.5	ZC15.5	n/a	chrV 20,294,125	contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
38	K09C4.2	K09C4.2	n/a	chrX 3,297,833
39	inft-2	F15B9.4	n/a	chrV 13,004,645	C. elegans INFT-2 protein; contains similarity to Pfam domain PF02181 Formin Homology 2 Domain contains similarity to Interpro domains IPR015425 (Actin-binding FH2), IPR000694 (Proline-rich region), IPR003104 (Actin-binding FH2 and DRF autoregulatory), IPR000976 (Wilm's tumour protein)
40	C18B12.1	C18B12.1	n/a	chrX 15,012,725	contains similarity to Bacillus anthracis Flagellar biosynthetic protein FlhB, putative.; TR:Q81SE5
41	Y32B12A.3	Y32B12A.3	n/a	chrV 16,494,024	contains similarity to Pfam domain PF01596 O-methyltransferase contains similarity to Interpro domain IPR002935 (O-methyltransferase, family 3)
42	K02B2.3	K02B2.3	n/a	chrIV 5,938,425	contains similarity to Pfam domain PF04678 Protein of unknown function, DUF607 contains similarity to Interpro domain IPR006769 (Protein of unknown function DUF607)
43	F15E11.4	F15E11.4	n/a	chrV 2,340,462	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
44	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
45	F16G10.15	F16G10.15	n/a	chrII 2,406,470	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
46	srp-6	C03G6.19	n/a	chrV 7,385,156	srp-6 encodes a functional serpin (serine protease inhibitor)
47	F59A2.6	F59A2.6	n/a	chrIII 3,420,133	contains similarity to Pfam domains PF02524 (KID repeat) , PF01465 (GRIP domain) contains similarity to Interpro domains IPR004089 (Chemotaxis methyl-accepting receptor, signalling), IPR000533 (Tropomyosin), IPR009053 (Prefoldin), IPR000237 (GRIP)
48	fbxb-86	T27E9.8	n/a	chrIII 13,478,975	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
49	T25B9.2	T25B9.2	n/a	chrIV 10,750,930	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
50	Y49E10.16	Y49E10.16	n/a	chrIII 12,432,047	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domains IPR002921 (Lipase, class 3), IPR008262 (Lipase, active site)