UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	hmt-1	W09D6.6	0	chrIII 11,095,634	hmt-1 encodes a predicted transmembrane half-molecule ATP-binding cassette (ABC) transporter orthologous to Schizosaccharomyces pombe heavy metal tolerance factor 1 (SpHMT1), an ATP-dependent phytochelatin transporter; HMT-1 is required for cadmium detoxification and by homology, is predicted to promote sequestration of heavy metal-containing phytochelatins into intracellular vacuoles to protect cells from potential damage.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	taf-2	Y37E11B.4	n/a	chrIV 3,588,951	taf-2 encodes a member of the peptidase M1 family, a predicted aminopeptidase with similarity to human TBP-associated factor 2.
4	F10E7.10	F10E7.10	n/a	chrII 7,114,773	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
5	chw-1	F22E12.2	n/a	chrV 10,463,355	C. elegans CHW-1 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
6	C52B9.8	C52B9.8	n/a	chrX 4,300,505	contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF07529 (HSA) , PF04851 (Type III restriction enzyme, res subunit) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR006935 (Restriction endonuclease, type I, R subunit/Type III, Res subunit), IPR013999 (HAS subgroup), IPR014012 (Helicase/SANT-associated, DNA binding), IPR000330 (SNF2-related), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR006562 (HSA), IPR005448 (Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
7	F49E7.2	F49E7.2	n/a	chrX 1,096,278
8	Y76G2A.2	Y76G2A.2	n/a	chrI 5,979,210
9	ZK430.1	ZK430.1	n/a	chrII 4,428,903	contains similarity to Pfam domain PF08146 BP28CT (NUC211) domain contains similarity to Interpro domains IPR012954 (BP28, C-terminal), IPR016024 (Armadillo-type fold)
10	tag-184	F18C5.3	n/a	chrII 6,550,797	C. elegans TAG-184 protein; contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
11	coq-6	K07B1.2	n/a	chrV 9,337,783	coq-6 encodes a putative flavin-dependent aromatic-ring monooxygenase, homologous to yeast COQ6; COQ-6 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; coq-6(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans.
12	F36D1.1	F36D1.1	n/a	chrI 11,278,248	contains similarity to Interpro domain IPR006578 (MADF)
13	clec-93	ZK39.4	n/a	chrI 11,143,094	C. elegans CLEC-93 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
14	zyg-8	Y79H2A.11	n/a	chrIII 12,066,888	The zyg-8 gene encodes a protein with a doublecortin-like domain and a protein kinase domain; mutations of zyg-8 impair mitosis at the one-cell embryonic stage, which is normally asymmetrical, but which fails to show proper asymmetry in zyg-8 mutant embryos.
15	clec-226	R10D12.5	n/a	chrV 13,947,830	C. elegans CLEC-226 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold)
16	F20C5.4	F20C5.4	n/a	chrIV 8,766,075	contains similarity to Pfam domain PF03381 LEM3 (ligand-effect modulator 3) family / CDC50 family contains similarity to Interpro domain IPR005045 (Protein of unknown function DUF284, transmembrane eukaryotic)
17	F32B6.9	F32B6.9	n/a	chrIV 9,904,788	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
18	Y43F4B.7	Y43F4B.7	n/a	chrIII 13,310,326	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR013057 (Amino acid transporter, transmembrane), IPR003568 (Cytochrome c-type biogenesis protein CcmF)
19	F33D11.5	F33D11.5	n/a	chrI 5,836,021	contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
20	his-68	T23D8.6	n/a	chrI 9,989,347	his-68 encodes an H2A histone.
21	dcs-1	Y113G7A.9	n/a	chrV 20,084,683	dcs-1 encodes a scavenger mRNA decapping enzyme; dcs-1 exhibits hydrolase activity in vitro, with specificity for 7meGMP in its primary nucleoside monophosphate binding site; dcs-1 is the upstream gene in an operon with fre-1, which encodes an NADPH-dependent flavin reductase; reporter fusions using dcs-1 upstream sequence direct expression throughout the life cycle in neurons and pharyngeal muscle; expression is present in dauer larvae and enhanced by heat shock.
22	srd-72	Y45G12C.9	n/a	chrV 2,533,025	C. elegans SRD-72 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR001614 (Myelin proteolipid protein PLP), IPR003002 (7TM chemoreceptor, subfamily 1), IPR002016 (Haem peroxidase, plant/fungal/bacterial)
23	F39F10.2	F39F10.2	n/a	chrX 16,895,317	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
24	T07F12.2	T07F12.2	n/a	chrX 4,891,246	contains similarity to Pfam domain PF02225 PA domain contains similarity to Interpro domain IPR003137 (Protease-associated PA)
25	cyp-43A1	E03E2.1	n/a	chrX 5,716,005	C. elegans CYP-43A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV)
26	pbo-4	K09C8.1	n/a	chrX 10,956,107	pbo-4 encodes a sodium/proton exchanger (also known as nhx-7), with a potential Ca[2+]/calmodulin binding domain in its C-terminal cytosolic region that could mediate calcium signaling; PBO-4 is expressed in the basolateral membrane of posterior intestinal cells; PBO-4 is required for normal posterior body muscle contraction (pBoc) during the defecation cycle; PBO-4 is thought to prevent intracellular acidification by catalysing the electroneutral exchange of extracellular sodium for an intracellular proton; specifically, PBO-4 may enable intercellular signals from intestinal cells (by secreting protons which then might activate PBO-5 in adjacent muscle cells).
27	W08F4.11	W08F4.11	n/a	chrII 593,637
28	C41D11.6	C41D11.6	n/a	chrI 4,461,426
29	K03B8.8	K03B8.8	n/a	chrV 11,410,221	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
30	ugt-11	T19H12.10	n/a	chrV 4,893,822	C. elegans UGT-11 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
31	srm-3	F58G6.2	n/a	chrIV 9,649,830	C. elegans SRM-3 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	W04G3.7	W04G3.7	n/a	chrX 11,084,822	contains similarity to Interpro domain IPR001211 (Phospholipase A2)
33	acr-11	D2092.3	n/a	chrI 6,623,291	A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
34	jmjd-2	Y48B6A.11	n/a	chrII 14,239,185	C. elegans JMJD-2 protein; contains similarity to Pfam domains PF02375 (jmjN domain) , PF02373 (JmjC domain) contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013129 (Transcription factor jumonji), IPR003347 (Transcription factor jumonji/aspartyl beta-hydroxylase), IPR003349 (Transcription factor jumonji, JmjN), IPR011011 (Zinc finger, FYVE/PHD-type), IPR002999 (Tudor)
35	sul-1	K09C4.8	n/a	chrX 3,269,056	sul-1 encodes a member of the sulfatase family.
36	Y49F6C.7	Y49F6C.7	n/a	chrII 3,367,722
37	E02H9.4	E02H9.4	n/a	chrIII 2,457,255	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
38	F09C8.1	F09C8.1	n/a	chrX 16,161,517	contains similarity to Pfam domain PF00657 GDSL-like Lipase/Acylhydrolase contains similarity to Interpro domains IPR001087 (Lipase, GDSL), IPR013830 (Esterase, SGNH hydrolase-type)
39	vhl-1	F08G12.4	n/a	chrX 11,307,692	vhl-1 is orthologous to the mammalian tumor suppressor gene Von Hippel-Landau syndrome (VHL; OMIM:193300), which is part of a ubiquitylation complex targetting proteins for proteasomal degradation.
40	srt-15	C50H11.10	n/a	chrV 3,060,908	C. elegans SRT-15 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
41	Y32B12B.1	Y32B12B.1	n/a	chrV 16,536,916	contains similarity to Leptospira kirschneri serovar grippotyphosa Hypothetical protein.; TR:Q8KWV2
42	ZK250.2	ZK250.2	n/a	chrII 1,949,294	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
43	C35B1.2	C35B1.2	n/a	chrIV 4,094,546	n/a
44	C46F11.4	C46F11.4	n/a	chrIII 3,661,086	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
45	rcq-5	E03A3.2	n/a	chrIII 4,055,367	C. elegans RCQ-5 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR004589 (DNA helicase, ATP-dependent, RecQ type), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
46	ZK1098.5	ZK1098.5	n/a	chrIII 9,526,211	ZK1098.5 encodes a unfamiliar protein that is individually dispensable for viability and gross morphology in RNAi assays, but is cotranscribed with ZK1098.1 and thus might act in concert with it.
47	fbxb-76	H02I12.2	n/a	chrIV 11,378,732	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
48	F44E5.3	F44E5.3	n/a	chrII 11,763,830	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000304160
49	F31D5.5	F31D5.5	n/a	chrII 4,199,547	contains similarity to Pfam domain PF01825 Latrophilin/CL-1-like GPS domain contains similarity to Interpro domain IPR000203 (GPS)
50	grl-6	K10C2.5	n/a	chrX 6,450,444	grl-6 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-6 is expressed in larval intestine, amphid socket cells, and neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.