UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxa-203	W05F2.5	0	chrI 3,372,801	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	T21H3.5	T21H3.5	n/a	chrV 1,159,760
4	str-170	T08B6.7	n/a	chrIV 4,878,848	C. elegans STR-170 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	C26C6.8	C26C6.8	n/a	chrI 7,504,574	contains similarity to Pfam domains PF07653 (Variant SH3 domain) (3), PF00018 (SH3 domain) (2)contains similarity to Interpro domains IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR011511 (Variant SH3)
6	F28H6.6	F28H6.6	n/a	chrX 14,121,403	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
7	R07E5.5	R07E5.5	n/a	chrIII 4,398,025	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
8	W02D9.9	W02D9.9	n/a	chrI 12,557,310	contains similarity to Bacteroides thetaiotaomicron Arabinose-proton symporter (Arabinose transporter).; TR:Q8AAL0
9	str-108	F10A3.13	n/a	chrV 16,166,795	C. elegans STR-108 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	Y69H2.1	Y69H2.1	n/a	chrV 18,621,264	contains similarity to Myxine glutinosa NADH-ubiquinone oxidoreductase chain 4 (EC 1.6.5.3).; SW:NU4M_MYXGL
11	C01F1.6	C01F1.6	n/a	chrII 4,285,393	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
12	rbr-2	ZK593.4	n/a	chrIV 10,923,428	rbr-2 encodes a histone H3 lysine 4 (H3K4) demethylase that is required for normally short lifespan and reliable vulval development, that regulates genome-wide levels of H3K4 trimethylation, and that interacts genetically with CLK-2, GLP-1, LIN-15, and SEM-5; RBR-2 is orthologous to budding yeast Jhd2p, Drosophila LID, and human JARID1A (OMIM:180202), JARID1B (OMIM:605393), JARID1C (OMIM:314690, mutated in mental retardation), and JARID1D (OMIM:426000); rbr-2(tm1231) homozygotes display excess trimethylated H3K4 (H3K4me3) and erratic vulval development (either vulvaless or multivulva); rbr-2(RNAi) animals show extended lifespans, a strong synthetic multivulva and H3K4me3 phenotype in a lin-15(n765ts) mutant background at permissive temperature, and abnormally slow growth with clk-2(mn159), glp-1(or178), or sem-5(n2019) mutant backgrounds.
13	C17A2.7	C17A2.7	n/a	chrII 3,842,652	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domains IPR004101 (Mur ligase, C-terminal), IPR002485 (Protein of unknown function DUF13)
14	nhr-189	F47C10.8	n/a	chrV 3,859,413	C. elegans NHR-189 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
15	F54E7.6	F54E7.6	n/a	chrIII 5,660,439
16	K09D9.12	K09D9.12	n/a	chrV 4,003,740
17	T05A8.7	T05A8.7	n/a	chrII 2,741,328
18	sre-37	F15A4.3	n/a	chrII 12,466,610	C. elegans SRE-37 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
19	F48G7.7	F48G7.7	n/a	chrV 626,072	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
20	nhr-32	K08H2.8	n/a	chrX 13,254,014	C. elegans NHR-32 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
21	Y56A3A.16	Y56A3A.16	n/a	chrIII 11,912,267	contains similarity to Homo sapiens Isoform 1 of Pleckstrin homology domain-containing family M member 3; ENSEMBL:ENSP00000373899
22	srh-48	C06C3.6	n/a	chrII 9,384,056	C. elegans SRH-48 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	C50E3.2	C50E3.2	n/a	chrV 7,610,647	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
24	F36H12.17	F36H12.17	n/a	chrIV 5,277,187
25	srt-6	R13D7.10	n/a	chrV 7,408,161	C. elegans SRT-6 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR008075 (Lipocalin-1 receptor)
26	R01H10.5	R01H10.5	n/a	chrIII 10,257,869	contains similarity to Homo sapiens Similar to TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa; ENSEMBL:ENSP00000218510
27	C01H6.9	C01H6.9	n/a	chrI 7,231,276	C01H6.9 encodes a homolog of haploid germ cell-specific nuclear protein kinase (haspin) that specifically binds GOA-1 in yeast two-hybrid assays; C01H6.9 is expressed in PHB sensory neurons and PVT interneurons in the tail, several unidentified neurons in the head (with projections to the nose and nerve ring), and intestinal cells, with mainly nuclear localization; C01H6.9 has no obvious function or phenotype in RNAi assays, either alone or with inactivation of a close paralog (F22H10.5).
28	Y54E2A.6	Y54E2A.6	n/a	chrII 14,768,030	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) (2), PF00271 (Helicase conserved C-terminal domain) (2), PF02889 (Sec63 Brl domain) (2)contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR004179 (Sec63), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
29	R02E4.1	R02E4.1	n/a	chrX 4,103,960
30	str-82	B0213.8	n/a	chrV 3,975,447	C. elegans STR-82 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000344 (Nematode chemoreceptor, Sra), IPR003002 (7TM chemoreceptor, subfamily 1)
31	C13C4.6	C13C4.6	n/a	chrV 12,123,359	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
32	sdc-2	C35C5.1	n/a	chrX 11,528,006	The sdc-2 gene encodes a protein that represses transcription of X chromosomes to achieve dosage compensation, and that also represses the male sex-determination gene her-1 to elicit hermaphrodite differentiation.
33	nhr-83	F48G7.3	n/a	chrV 632,120	C. elegans NHR-83 protein; contains similarity to Pfam domains PF07914 (Protein of unknown function (DUF1679)) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core), IPR015897 (CHK kinase-like)
34	dat-1	T23G5.5	n/a	chrIII 9,244,759	dat-1 encodes a plasma membrane dopamine transporter; DAT-1 is predicted to regulate dopaminergic neurotransmission via reuptake of dopamine into presynaptic neurons; when expressed in HeLa cells, DAT-1 exhibits high affinity, saturable dopamine transport; further, in primary cultures of C. elegans dopaminergic neurons, DAT-1 also exhibits a channel mode of conduction that leads to membrane depolarization; in hermaphrodites, dat-1 is expressed in the eight dopaminergic neurons (4 CEPs, 2 ADEs, and 2 PDEs), while in males dat-1 is additionally expressed in the three pairs of tail dopaminergic neurons; dat-1 expression begins during embryogenesis with the exception of expression in the PDE neurons which are born postembryonically.
35	H10E21.2	H10E21.2	n/a	chrIII 10,398	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
36	srh-131	Y102A5C.31	n/a	chrV 17,006,090	C. elegans SRH-131 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	ZK470.4	ZK470.4	n/a	chrX 4,139,617
38	tbx-32	ZK380.1	n/a	chrX 1,656,225	C. elegans TBX-32 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
39	F17C11.6	F17C11.6	n/a	chrV 10,955,512	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q9ZT77
40	ugt-37	F10D2.6	n/a	chrV 7,143,012	C. elegans UGT-37 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
41	C10E2.4	C10E2.4	n/a	chrX 16,750,349
42	F52E10.3	F52E10.3	n/a	chrX 16,283,853	contains similarity to Salmonella typhimurium Secretion system apparatus protein ssaM.; SW:SSAM_SALTY
43	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
44	clec-188	M199.3	n/a	chrIV 15,117,866	C. elegans CLEC-188 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
45	C33C12.9	C33C12.9	n/a	chrII 2,188,303	contains similarity to Pfam domain PF05175 Methyltransferase small domain contains similarity to Interpro domains IPR007848 (Methyltransferase small), IPR004557 (Putative methylase), IPR002296 (N6 adenine-specific DNA methyltransferase, N12 class), IPR002052 (N-6 adenine-specific DNA methylase, conserved site)
46	nhr-78	F36A4.14	n/a	chrIV 4,276,441	C. elegans NHR-78 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
47	Y51A2A.5	Y51A2A.5	n/a	chrV 18,299,724	contains similarity to Saccharomyces cerevisiae transcription factor tau (TFIIIC) subunit 95; SGD:YBR123C
48	F58B3.6	F58B3.6	n/a	chrIV 11,637,391	contains similarity to Pfam domains PF04836 (Interferon-related protein conserved region) , PF05004 (Interferon-related developmental regulator (IFRD)) contains similarity to Interpro domains IPR007701 (Interferon-related developmental regulator), IPR006921 (Interferon-related protein conserved region), IPR016024 (Armadillo-type fold)
49	his-12	ZK131.6	n/a	chrII 13,821,298	his-12 encodes an H2A histone; his-12 is contained within the histone gene cluster HIS3.
50	grl-28	T24A6.15	n/a	chrV 3,551,603	grl-28 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.