UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	W04G3.2	W04G3.2	0	chrX 11,063,262	contains similarity to Saccharomyces cerevisiae Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes; SGD:YGR097W
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	lgc-7	Y57G11C.2	n/a	chrIV 14,712,127	C. elegans LGC-7 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
4	Y53C12A.3	Y53C12A.3	n/a	chrII 9,705,022	contains similarity to Pfam domains PF03942 (DTW domain) , PF04893 (Yip1 domain) contains similarity to Interpro domains IPR006977 (Yip1 domain), IPR005636 (DTW)
5	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
6	C26B2.7	C26B2.7	n/a	chrIV 8,016,527
7	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
8	F55D12.2	F55D12.2	n/a	chrI 7,892,099	contains similarity to Interpro domains IPR002017 (Spectrin repeat), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal)
9	ape-1	F46F3.4	n/a	chrV 11,680,585	ape-1 encodes an ortholog of inhibitory p53-interacting protein (iASPP); APE-1 binds CEP-1 in vitro, and shares 38% amino-acid identity in its ankyrin repeats and SH3 domain to iASPP, with many iASPP residues contacting p53 being conserved; RNAi of ape-1 induces CEP-1- and HUS-1-dependent apoptosis in the germline, consistent with inhibition of the CEP-1/HUS-1 DNA damage checkpoint by APE-1 in the germline; excess ape-1(RNAi) apoptosis also requires CED-3.
10	C01F6.1	C01F6.1	n/a	chrIV 9,098,665	C01F6.1 encodes a putative calcium-dependent phospholipid binding protein of the copine family; C01F6.1 is required for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; C01F6.1(RNAi) hermaphrodites are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them.
11	dbl-1	T25F10.2	n/a	chrV 6,759,095	dbl-1 encodes a member of the transforming growth factor beta (TGFbeta) superfamily that includes Drosophila decapentaplegic (Dpp) and the vertebrate bone morphogenetic proteins (BMPs); DBL-1 functions as a dose-dependent ligand for the SMA-6 and DAF-4 TGFbeta receptors that ultimately activate the SMA-2, -3, and -4 complex of transcription factors to regulate body length and size, as well as the patterning of male sensory rays and copulatory spicules; DBL-1 signaling upregulates sma-6 expression, suggesting that there is positive autoregulation in the DBL-1 signaling pathway; in contrast, DBL-1 negatively regulates expression of LON-1, a predicted secreted protein that is a downstream component of the body size pathway; DBL-1 is expressed primarily in neurons.
12	Y62H9A.7	Y62H9A.7	n/a	chrX 11,885,307	contains similarity to Mus musculus Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterases1A (EC 3.1.4.17) (Cam-PDE 1A) (61 kDa Cam-PDE).; SW:CN1A_MOUSE
13	ZK218.1	ZK218.1	n/a	chrV 17,092,954	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
14	B0035.6	B0035.6	n/a	chrIV 11,322,187	contains similarity to Saccharomyces cerevisiae Structural maintenance of chromosomes (SMC) protein; SGD:YOL034W
15	srx-22	F31F4.3	n/a	chrV 680,688	C. elegans SRX-22 protein ;
16	srj-10	F14H3.1	n/a	chrV 16,073,333	C. elegans SRJ-10 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	F21G4.4	F21G4.4	n/a	chrX 9,898,328	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
18	srg-9	T12A2.10	n/a	chrIII 6,256,061	C. elegans SRG-9 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
19	W06A11.1	W06A11.1	n/a	chrII 4,068,658
20	C08E3.13	C08E3.13	n/a	chrII 1,632,158	C08E3.13 encodes a novel protein; expression studies indicate that C08E3.13 expression is positively regulated by signaling through the DBL-1/TGF-beta signaling pathway; in situ hybridization experiments reveal that C08E3.13 transcripts are expressed in the intestine and the vulva.
21	srd-17	Y2H9A.2	n/a	chrV 13,431,663	C. elegans SRD-17 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	ZK177.9	ZK177.9	n/a	chrII 5,517,477
23	R11G10.2	R11G10.2	n/a	chrV 13,513,568	contains similarity to Pfam domain PF05694 56kDa selenium binding protein (SBP56) contains similarity to Interpro domain IPR008826 (Selenium-binding protein)
24	C34D4.10	C34D4.10	n/a	chrIV 7,120,692
25	T25G12.2	T25G12.2	n/a	chrX 17,245,951	The T25G12.2 gene encodes a homolog of the human gene HSD, which when mutated leads to cortisol 11-beta ketoreductase deficiency (OMIM:218030); T25G12.2 protein is predicted to be mitochondrial with 68% accuracy.
26	F20B4.2	F20B4.2	n/a	chrX 17,704,274
27	K04E7.1	K04E7.1	n/a	chrX 6,462,585
28	Y57G7A.6	Y57G7A.6	n/a	chrII 1,283,801	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
29	W09G12.8	W09G12.8	n/a	chrIV 1,226,925	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
30	grd-10	F09D12.1	n/a	chrIV 3,441,427	grd-10 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; GRD-10 is expressed in seam cells; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-10 is weakly required for normal molting; GRD-10 is also required for normal growth to full size and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
31	T14G8.2	T14G8.2	n/a	chrX 12,858,701	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
32	sri-7	T06E6.4	n/a	chrV 15,401,049	C. elegans SRI-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	srh-72	ZC204.5	n/a	chrII 1,639,907	C. elegans SRH-72 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	F10C2.5	F10C2.5	n/a	chrV 12,047,001	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domains IPR010916 (TonB box, conserved site), IPR001382 (Glycoside hydrolase, family 47)
35	Y62H9A.11	Y62H9A.11	n/a	chrX 11,906,196
36	srh-82	W03F9.6	n/a	chrV 146,062	C. elegans SRH-82 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	B0348.1	B0348.1	n/a	chrV 49,270	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
38	F21G4.3	F21G4.3	n/a	chrX 9,896,105	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
39	T05C1.3	T05C1.3	n/a	chrII 4,488,577
40	xnp-1	B0041.7	n/a	chrI 4,668,742	xnp-1 encodes an ATP-dependent DNA helicase of the SNF2 family that is orthologous to human XNP/ATR-X, which is associated with a number of X-linked mental retardation syndromes; in C. elegans, xnp-1 activity is required at high temperatures for embryogenesis, somatic gonad development, fertility, and vulval morphogenesis; in addition, animals doubly mutant for xnp-1 and lin-35/Rb, hpl-2/HP1, or nucleosome remodelling and histone deacetylase (NuRD) complex members such as lin-53 and let-418, display larval arrest with growth cessation but continued cell proliferation; xnp-1 is also required, with lin-35/Rb and hpl-2/HP1, for proper regulation of transgene expression; xnp-1 mRNA, detectable in embryos and the germline by in situ hybridization, is expressed at highest levels in embryos with decreasing levels seen in successive larval stages; xnp-1 transcriptional reporter fusions exhibit strong expression beginning at mid-embryogenesis but fading by embryonic morphogenesis; at hatching, expression is observed in all dividing cells including the P lineage, and at later larval stages expression is observed in the vulval precursor cells.
41	srx-7	C14C6.1	n/a	chrV 561,828	C. elegans SRX-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
42	srxa-9	ZK678.4	n/a	chrX 15,749,493	C. elegans SRXA-9 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
43	srj-7	T28A11.10	n/a	chrV 3,245,861	C. elegans SRJ-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	Y54C5A.1	Y54C5A.1	n/a	chrII 4,140,997
45	fbxa-89	Y75B8A.21	n/a	chrIII 12,237,580	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
46	K03D7.9	K03D7.9	n/a	chrV 17,488,056	contains similarity to Homo sapiens Olfactory receptor 1A1; ENSEMBL:ENSP00000305207
47	C53B4.6	C53B4.6	n/a	chrIV 8,985,786	contains similarity to Pfam domain PF08449 UAA transporter family contains similarity to Interpro domain IPR013657 (UAA transporter)
48	W01C8.1	W01C8.1	n/a	chrX 5,693,921
49	srh-55	T09F5.5	n/a	chrV 15,154,261	C. elegans SRH-55 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	str-161	T08B6.3	n/a	chrIV 4,903,231	C. elegans STR-161 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)