UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	W04A8.4	W04A8.4	2e-72	chrI 13,842,557	contains similarity to Pfam domain PF01612 3'-5' exonuclease contains similarity to Interpro domains IPR002562 (3'-5' exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
4	ins-2	ZK75.2	n/a	chrII 5,988,821	ins-2 encodes an insulin-like peptide.
5	T04B8.3	T04B8.3	n/a	chrII 628,093	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
6	F46E10.2	F46E10.2	n/a	chrV 6,520,674	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR001030 (Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)
7	skr-21	K08H2.1	n/a	chrX 13,226,159	The skr-21 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-21(RNAi) animals are at least superficially normal.
8	F56A8.8	F56A8.8	n/a	chrIII 13,286,178	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IHP7
9	ces-2	ZK909.4	n/a	chrI 14,963,425	ces-2 encodes a basic region leucine-zipper (bZIP) transcription factor, most similar in sequence and binding specificity to the PAR (proline- and acid-rich) subfamily of bZIP proteins; ces-2 is required to activate programmed cell death in the sister cells of the serotoninergic neurosecretory motor (NSM) neurons, and is transcriptionally inhibited by activated LET-60(G12V).
10	hil-3	F22F1.1	n/a	chrX 8,159,562	C. elegans HIL-3 protein; contains similarity to Pfam domain PF00538 linker histone H1 and H5 family contains similarity to Interpro domains IPR003993 (Treacher Collins syndrome, treacle), IPR011991 (Winged helix repressor DNA-binding), IPR005819 (Histone H5), IPR005818 (Histone H1/H5)
11	R07C3.11	R07C3.11	n/a	chrII 908,164
12	Y7A9D.1	Y7A9D.1	n/a	chrIV 16,381,762	contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
13	clec-196	F26D10.12	n/a	chrIV 17,277,281	C. elegans CLEC-196 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
14	Y106G6D.2	Y106G6D.2	n/a	chrI 10,111,416	contains similarity to Homo sapiens hypothetical protein LOC283767; ENSEMBL:ENSP00000347269
15	com-1	C44B9.5	n/a	chrIII 10,898,988	com-1 encodes an ortholog of budding yeast Sae2p, Arabidopsis AtCOM1, and human RBBP8 (CTIP; OMIM:604124) and C20orf151; like its yeast ortholog, COM-1 is probably required for completing meiotic recombination; meiotic chromosomes in com-1 mutants pair normally, but form irregular chromatin aggregates instead of diakinesis bivalents; while meiotic DNA double-strand breaks (DSBs) are formed, they appear to persist or undergo improper repair, with numerous chromosomal fragments being revealed by REC-8 depletion; conversely, suppression of DSBs by a spo-11 mutation also suppresses the diakinetic com-1 phenotype, and suppression by mre-11 increases com-1 mutant fertility; despite the presence of DSBs, the recombination protein RAD-51, which is known to associate with single-stranded (ss) DNA flanking DSBs, does not localize to meiotic chromosomes in com-1 mutants; exposure of com-1 mutants to gamma-radiation, however, induces RAD-51 foci, which suggests that the failure of RAD-51 to load is specific to meiotic (SPO-11-generated) DSBs; these data suggest that COM-1 helps generate ssDNA tails upon which RAD-51 can bind, after which RAD-51 migrates to homologous DNA tracts and triggers meiotic recombination; com-1 mutants grow and live normally (possibly because of maternally contributed COM-1) but are sterile; the C-terminal-most ~100 residues of COM-1 are strongly conserved, while COM-1's N-terminal ~400 residues have low sequence complexity.
16	K08B4.2	K08B4.2	n/a	chrIV 6,075,712
17	cut-3	F22B5.3	n/a	chrII 8,445,930	C. elegans CUT-3 protein; contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
18	ZK418.3	ZK418.3	n/a	chrIII 7,070,514	contains similarity to Homo sapiens Transmembrane protein 17; ENSEMBL:ENSP00000335094
19	ZK675.4	ZK675.4	n/a	chrII 7,911,649	contains similarity to Homo sapiens Nuclear pore glycoprotein p62; ENSEMBL:ENSP00000305503
20	col-74	ZK1248.2	n/a	chrII 5,831,409	C. elegans COL-74 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domain IPR008160 (Collagen triple helix repeat)
21	F13H10.1	F13H10.1	n/a	chrIV 11,004,784	contains similarity to Oryza sativa Putative pM5 collagenase.; TR:Q93W04
22	F28D1.2	F28D1.2	n/a	chrIV 12,375,385	contains similarity to Homo sapiens Myelin transcription factor 1; ENSEMBL:ENSP00000327465
23	T09D3.3	T09D3.3	n/a	chrV 5,348,079	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR013032 (EGF-like region, conserved site)
24	his-24	M163.3	n/a	chrX 14,490,530	The his-24 gene encodes a histone H1 isoform (H1.1) that is essential for chromatin silencing and germline development.
25	sdz-25	M116.4	n/a	chrIV 8,405,798	C. elegans SDZ-25 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
26	C33D9.5	C33D9.5	n/a	chrIV 8,779,611	C33D9.5 encodes a predicted coiled-coil protein; as loss of C33D9.5 activity via large-scale RNAi results in no obvious abnormalities, the precise role of C33D9.5 in C. elegans development and/or behavior is not yet known.
27	C41H7.2	C41H7.2	n/a	chrII 3,015,393	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
28	R07C3.9	R07C3.9	n/a	chrII 912,522
29	sdz-33	Y56A3A.14	n/a	chrIII 11,907,882	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
30	C33E10.1	C33E10.1	n/a	chrX 17,305,742	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
31	T23B3.2	T23B3.2	n/a	chrI 6,716,467	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
32	cut-6	M142.2	n/a	chrIII 10,913,915	C. elegans CUT-6 protein; contains similarity to Pfam domains PF00100 (Zona pellucida-like domain) , PF00092 (von Willebrand factor type A domain) contains similarity to Interpro domains IPR001507 (Endoglin/CD105 antigen), IPR002035 (von Willebrand factor, type A)
33	fbxb-8	F49B2.1	n/a	chrI 14,302,931	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
34	C31H5.4	C31H5.4	n/a	chrI 9,042,426	contains similarity to Oryza sativa P0681F05.20 protein.; TR:Q8GVP7
35	fbxb-16	ZC204.10	n/a	chrII 1,651,202	fbxb-16 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-16 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
36	sdz-28	R52.1	n/a	chrII 2,131,740	C. elegans SDZ-28 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
37	fbxb-22	Y56A3A.10	n/a	chrIII 11,882,947	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
38	ceh-43	C28A5.4	n/a	chrIII 4,448,260	A homeobox protein of the Distal-less (Dll) class that is required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability; it is predominantly expressed in the head hypdodermis, neuronal support cells and CAN neurons.
39	btb-11	M01D1.3	n/a	chrII 1,024,269	C. elegans BTB-11 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
40	ppt-1	F44C4.5	n/a	chrV 6,625,504	ppt-1 encodes the C. elegans palmitoyl protein thioesterase-1 ortholog; by homology PPT-1 is predicted to function in degradation of palmitoylated proteins and ppt-1 mutations result in loss of enzymatic activity from mixed-stage extracts; in C. elegans, ppt-1 activity is essential for mitochondrial organization and biogenesis in neuronal and muscle cells, as well as for proper timing of the onset of both the L4-to-adult molt and egg laying; ppt-1 is also required for normal egg-laying behavior and for a fully normal adult
41	fbxb-26	F58E1.3	n/a	chrII 1,683,034	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
42	T05E7.5	T05E7.5	n/a	chrI 6,201,572	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
43	F48E3.6	F48E3.6	n/a	chrX 7,501,882
44	fbxb-82	T17A3.4	n/a	chrIII 142,689	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
45	fbxb-24	Y56A3A.15	n/a	chrIII 11,909,309	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
46	F20C5.6	F20C5.6	n/a	chrIV 8,772,362	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2DLG0
47	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
48	T24C4.2	T24C4.2	n/a	chrIII 868,674
49	C49C3.8	C49C3.8	n/a	chrIV 17,335,930	contains similarity to Interpro domains IPR006570 (SPK), IPR009057 (Homeodomain-like)
50	fbxb-32	M151.6	n/a	chrII 3,646,198	C. elegans FBXB-32 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)