UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxb-55	W03D2.2	8e-142	chrIV 4,069,157	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	F31A3.5	F31A3.5	n/a	chrX 17,558,148	contains similarity to Interpro domain IPR000694 (Proline-rich region)
5	W03C9.1	W03C9.1	n/a	chrII 11,961,452	contains similarity to Homo sapiens RNA binding protein; ENSEMBL:ENSP00000301740
6	C08G9.2	C08G9.2	n/a	chrIV 7,668,512	contains similarity to Pfam domains PF02822 (Antistasin family) (6), PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) , PF00095 (WAP-type (Whey Acidic Protein) 'four-disulfide core') (8), PF00086 (Thyroglobulin type-1 repeat) (6)contains similarity to Interpro domains IPR000716 (Thyroglobulin type-1), IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR008197 (Whey acidic protein, 4-disulphide core), IPR008198 (Proteinase inhibitor I17), IPR006150 (Cysteine-rich repeat), IPR013032 (EGF-like region, conserved site), IPR004094 (Proteinase inhibitor I15, antistasin), IPR015874 (4-disulphide core), IPR007087 (Zinc finger, C2H2-type), IPR003645 (Follistatin-like, N-terminal), IPR000737 (Proteinase inhibitor I7, squash)
7	set-10	F33H2.7	n/a	chrI 15,029,120	set-10 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-10 is paralogous to SET-14, SET-18, and SET-30; SET-10 has no obvious function in individual RNAi assays of vulval development, or in mass RNAi assays.
8	F09C8.1	F09C8.1	n/a	chrX 16,161,517	contains similarity to Pfam domain PF00657 GDSL-like Lipase/Acylhydrolase contains similarity to Interpro domains IPR001087 (Lipase, GDSL), IPR013830 (Esterase, SGNH hydrolase-type)
9	Y47D3B.4	Y47D3B.4	n/a	chrIII 11,407,290	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
10	srh-247	C31B8.13	n/a	chrV 2,933,658	C. elegans SRH-247 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	F55G1.1	F55G1.1	n/a	chrIV 7,492,779
12	srm-3	F58G6.2	n/a	chrIV 9,649,830	C. elegans SRM-3 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	srab-13	F59A7.3	n/a	chrV 2,026,295	C. elegans SRAB-13 protein ;
14	C01G10.9	C01G10.9	n/a	chrV 15,083,391	contains similarity to Pfam domain PF01008 Initiation factor 2 subunit family contains similarity to Interpro domains IPR000649 (Initiation factor 2B related), IPR011559 (Initiation factor 2B alpha/beta/delta)
15	T01A4.3	T01A4.3	n/a	chrI 4,465,379	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
16	tag-184	F18C5.3	n/a	chrII 6,550,797	C. elegans TAG-184 protein; contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
17	T16G12.4	T16G12.4	n/a	chrIII 10,058,154	contains similarity to Treponema denticola FlhB.; TR:Q9APY7
18	sri-31	B0454.2	n/a	chrII 3,051,657	C. elegans SRI-31 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	T20D4.13	T20D4.13	n/a	chrV 3,392,486
20	Y45G12C.11	Y45G12C.11	n/a	chrV 2,551,494	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
21	W04G3.7	W04G3.7	n/a	chrX 11,084,822	contains similarity to Interpro domain IPR001211 (Phospholipase A2)
22	fbxa-157	C06H5.2	n/a	chrV 17,900,819	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
23	C32B5.4	C32B5.4	n/a	chrII 980,130	contains similarity to Interpro domains IPR000931 (Adenovirus fibre protein), IPR008893 (WGR)
24	srj-21	F28H7.11	n/a	chrV 10,745,530	C. elegans SRJ-21 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	C50F2.4	C50F2.4	n/a	chrI 3,890,325
26	F41E7.6	F41E7.6	n/a	chrX 10,308,733	contains similarity to Pfam domain PF00755 Choline/Carnitine o-acyltransferase contains similarity to Interpro domain IPR000542 (Acyltransferase ChoActase/COT/CPT)
27	unc-8	R13A1.4	n/a	chrIV 7,200,978	unc-8 encodes an amiloride-sensitive DEG/ENaC cation-selective channel subunit orthologous to human ENaCB (OMIM:600760, associated with Liddle syndrome, an autosomal dominant form of hypertension); UNC-8 is predicted to function as part of a mechanically gated channel that responds to stretch, and is required for modulating the sinusoidal body wave that is characteristic of C. elegans locomotion; unc-8 interacts genetically with unc-1 and unc-24, which encode stomatin-like proteins, and with mec-6, which encodes a paraoxonase; UNC-8 is expressed in motor neurons, sensory neurons, and interneurons in the nerve ring; UNC-8 may form a channel with the degenerin DEL-1, with which it is coexpressed in ventral cord motor neurons.
28	math-14	C16C4.4	n/a	chrII 1,870,071	C. elegans MATH-14 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR001712 (Type III secretion system FHIPEP)
29	npp-7	T19B4.2	n/a	chrI 5,694,480	C. elegans NPP-7 protein; contains similarity to Interpro domain IPR001876 (Zinc finger, RanBP2-type)
30	crb-1	F11C7.4	n/a	chrX 17,408,117	crb-1 encodes a homolog of Drosophila CRUMBS that affects dauer formation and feeding behavior; CRB-1 can bind cyclic AMP-response element (CRE) sites and be phosphorylated by PKA in vitro, and is expressed immediately apical to the zonula adherens in embryos and then ubiquitously later during development and in adults; CRB-1 is homologous to human CRB1 (OMIM:604210, mutated in retinitis pigmentosa 12 or Leber congenital amaurosis).
31	F52B11.5	F52B11.5	n/a	chrIV 14,102,592	contains similarity to Clostridium perfringens Hypothetical protein CPE2159.; TR:Q8XIG1
32	grl-6	K10C2.5	n/a	chrX 6,450,444	grl-6 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-6 is expressed in larval intestine, amphid socket cells, and neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
33	tmbi-4	B0563.4	n/a	chrX 9,155,606	C. elegans TMBI-4 protein; contains similarity to Pfam domain PF01027 Uncharacterised protein family UPF0005 contains similarity to Interpro domain IPR006214 (Protein of unknown function UPF0005)
34	D1065.1	D1065.1	n/a	chrV 4,075,636	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
35	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
36	zyg-8	Y79H2A.11	n/a	chrIII 12,066,888	The zyg-8 gene encodes a protein with a doublecortin-like domain and a protein kinase domain; mutations of zyg-8 impair mitosis at the one-cell embryonic stage, which is normally asymmetrical, but which fails to show proper asymmetry in zyg-8 mutant embryos.
37	F13G3.3	F13G3.3	n/a	chrI 7,298,454	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
38	T07F12.2	T07F12.2	n/a	chrX 4,891,246	contains similarity to Pfam domain PF02225 PA domain contains similarity to Interpro domain IPR003137 (Protease-associated PA)
39	C18H9.5	C18H9.5	n/a	chrII 6,693,979	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
40	dhs-25	F09E10.3	n/a	chrX 1,487,910	dhs-25 encodes a short-chain dehydrogenase predicted to be mitochondrial.
41	scm-1	M01D7.2	n/a	chrI 1,867,460	C. elegans SCM-1 protein; contains similarity to Pfam domain PF04144 SCAMP family contains similarity to Interpro domains IPR001395 (Aldo/keto reductase), IPR007273 (SCAMP)
42	T02G5.11	T02G5.11	n/a	chrII 7,080,284	contains similarity to Pfam domain PF05741 Nanos RNA binding domain contains similarity to Interpro domain IPR008705 (Zinc finger, Nanos)
43	C33H5.1	C33H5.1	n/a	chrIV 7,809,904	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
44	F11A1.2	F11A1.2	n/a	chrX 10,658,016
45	F40G9.1	F40G9.1	n/a	chrIII 196,177	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
46	T08G5.9	T08G5.9	n/a	chrV 14,045,861	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
47	bath-13	F40B1.1	n/a	chrII 2,521,505	C. elegans BATH-13 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
48	C14E2.5	C14E2.5	n/a	chrX 1,824,473
49	T10E10.4	T10E10.4	n/a	chrX 6,318,637	T10E10.4 encodes a large (966-residue) protein, predicted to be secreted, with two N-terminal chitin-binding peritrophin-A domains followed by 14 cysteine-rich domains and one C-terminal EB module; the general organization of T10E10.4 protein resembles that of K04H4.2; T10E10.4 has no obvious function in mass RNAi assays but, like CEJ-1 and CPG-2, might participate in chitin synthesis.
50	hmt-1	W09D6.6	n/a	chrIII 11,095,634	hmt-1 encodes a predicted transmembrane half-molecule ATP-binding cassette (ABC) transporter orthologous to Schizosaccharomyces pombe heavy metal tolerance factor 1 (SpHMT1), an ATP-dependent phytochelatin transporter; HMT-1 is required for cadmium detoxification and by homology, is predicted to promote sequestration of heavy metal-containing phytochelatins into intracellular vacuoles to protect cells from potential damage.