UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	glb-27	W01C9.5	2e-128	chrII 8,548,030	glb-27 encodes a globin whose expression is probably induced by anoxia in a HIF-1-dependent manner; glb-27 transcription is higher in L3 and dauers than in young adults; glb-27 has no obvious function in mass RNAi assays.
2	C13A10.2	C13A10.2	n/a	chrII 1,357,598
3	R10H10.4	R10H10.4	n/a	chrIV 10,394,780	contains similarity to Arabidopsis thaliana T15B16.1 protein.; TR:Q9ZSH8
4	C55A1.6	C55A1.6	n/a	chrV 15,648,434	contains similarity to Lactococcus lactis Protein maturation protein.; TR:Q9CEV9
5	W03G1.5	W03G1.5	n/a	chrIV 505,834	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR000694 (Proline-rich region), IPR002964 (Adhesive plaque protein)
6	odr-3	C34D1.3	n/a	chrV 13,248,189	odr-3 encodes a G protein alpha subunit; odr-3 activity is required for normal chemotaxis, odorant avoidance, and nociceptive function as well as cilium morphogenesis in chemosensory neurons; an ODR-3::GFP is expressed in five pairs of sensory neurons AWA, AWB, AWC, ASH, and ADF; the AWC neurons consistently express GFP most strongly, while the AWB neurons express at lower levels and the AWA, ASH, and ADF neurons express only weakly; in AWC neurons, ODR-3::GFP localizes to cilia which have a characteristic wing-shaped morphology.
7	cpx-2	K03A11.2	n/a	chrX 13,067,761	C. elegans CPX-2 protein; contains similarity to Pfam domain PF05835 Synaphin protein contains similarity to Interpro domain IPR008849 (Synaphin)
8	F10F2.4	F10F2.4	n/a	chrIII 4,624,572	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
9	pqn-97	ZK488.10	n/a	chrV 609,465	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
10	clec-10	C03H5.1	n/a	chrII 403,400	C. elegans CLEC-10 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
11	rgs-1	C05B5.7	n/a	chrIII 10,015,270	rgs-1 encodes a regulator of G protein signaling; by homology, RGS-1 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-1 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-1 appears to function redundantly with rgs-2 to regulate egg-laying behavior when animals are refed following starvation; rgs-1 is expressed in most or all neurons.
12	F36D4.4	F36D4.4	n/a	chrV 9,404,118	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000832 (GPCR, family 2, secretin-like), IPR000276 (GPCR, rhodopsin-like)
13	nhr-260	C38C3.9	n/a	chrV 1,510,828	C. elegans NHR-260 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
14	npr-3	C10C6.2	n/a	chrIV 11,461,555	C10C6.2 encodes a G-protein-coupled receptor for the FMRFamide-related peptides (FaRPs) encoded by flp-15; C10C6.2 is primarily coupled to Gi/Go proteins, since C10C6.2 signalling is blocked by pertussis toxin; because of its link to Gi/Go proteins, C10C6.2 is expected to be inhibitory
15	K02F6.5	K02F6.5	n/a	chrII 2,535,834	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
16	C32B5.11	C32B5.11	n/a	chrII 949,051
17	med-1	T24D3.1	n/a	chrX 12,430,862	The med-1 gene encodes a GATA-type transcription factor that is an immediate target of maternal SKN-1, and that participates in specifying the mesendoderm.
18	C50C3.5	C50C3.5	n/a	chrIII 8,179,701	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000261 (EPS15 homology (EH))
19	F10E9.1	F10E9.1	n/a	chrIII 8,323,702
20	F08H9.4	F08H9.4	n/a	chrV 14,463,959	F08H9.4 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the excretory canal and ventral nerve-cord neurons), and its expression is only mildly induced by heat shock; however, F08H9.4 expression is increased by heat shock, is induced in a new tissue type (intestine) by heat shock, and probably aids heat shock resistance, since F08H9.4(RNAi) animals die as embryos in heat shock at a higher rate than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.
21	glc-3	ZC317.3	n/a	chrV 5,451,485	The glc-3 gene encodes a fipronil and BIDN-sensitive, but picrotoxinin-insensitive, L-glutamate-gated chloride channel subunit.
22	lgc-37	ZC482.5	n/a	chrIII 12,789,021	ZC482.5 is orthologous to the human gene GAMMA-AMINOBUTYRIC ACID A RECEPTOR GAMMA 2 (GABRG2; OMIM:137164), which when mutated leads to disease.
23	ubc-22	C06E2.7	n/a	chrX 8,868,414	ubc-22 encodes an E2 ubiquitin-conjugating enzyme orthologous to Saccharomyces cerevisiae UBC8 and human UBC1/HIP2 (Huntingtin interacting protein 2, OMIM:602846) which are involved in regulating fructose-1,6-bisphosphatase and huntingtin catabolism, respectively; by homology, UBC-22 is likely required for covalent attachment of ubiquitin to select target proteins to facilitate their degradation; however, as loss of UBC-22 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of UBC-22 in C. elegans development and/or behavior is not yet known.
24	gpc-1	K02A4.2	n/a	chrX 12,881,921	The gpc-1 gene encodes a heterotrimeric guanine nucleotide-binding protein gamma subunit, expressed specifically in sensory neurons, that is involved in taste adaptation.
25	C55A1.7	C55A1.7	n/a	chrV 15,647,283	contains similarity to Escherichia coli TolA protein.; SW:TOLA_ECOLI
26	F09C3.2	F09C3.2	n/a	chrI 14,273,068	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR005833 (Haloacid dehydrogenase/epoxide hydrolase), IPR005834 (Haloacid dehalogenase-like hydrolase)
27	sue-1	F07A5.5	n/a	chrI 7,365,960	C. elegans SUE-1 protein; contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR013032 (EGF-like region, conserved site)
28	ZC239.3	ZC239.3	n/a	chrII 3,216,335	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
29	srbc-50	F54B8.8	n/a	chrV 15,824,406	C. elegans SRBC-50 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
30	ZC168.2	ZC168.2	n/a	chrIV 10,728,759	contains similarity to Pfam domain PF01147 Crustacean CHH/MIH/GIH neurohormone family contains similarity to Interpro domain IPR001166 (Crustacean neurohormone)
31	F10G2.7	F10G2.7	n/a	chrV 7,335,453	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
32	nhr-17	C02B4.2	n/a	chrX 12,665,768	nhr-17 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
33	ZC412.1	ZC412.1	n/a	chrV 14,855,683	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
34	C18H7.9	C18H7.9	n/a	chrIV 603,317	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
35	F58E6.1	F58E6.1	n/a	chrV 9,742,698	n/a
36	paf-1	W03G9.6	n/a	chrI 4,985,729	paf-1 encodes one of two C. elegans homologs of mammalian Type II platelet-activating factor-acetylhydrolase (PAF-AH).
37	D2062.1	D2062.1	n/a	chrII 2,632,264	contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related)
38	F47B10.8	F47B10.8	n/a	chrX 10,905,841	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
39	F49C12.10	F49C12.10	n/a	chrIV 9,318,735	contains similarity to Pfam domain PF08241 Methyltransferase domain contains similarity to Interpro domain IPR013216 (Methyltransferase type 11)
40	F20B6.4	F20B6.4	n/a	chrX 4,194,407
41	C47D2.1	C47D2.1	n/a	chrX 8,215,243
42	F26A1.8	F26A1.8	n/a	chrIII 4,821,475	contains similarity to Interpro domain IPR000010 (Proteinase inhibitor I25, cystatin)
43	K02F6.8	K02F6.8	n/a	chrII 2,533,862	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
44	Y42A5A.1	Y42A5A.1	n/a	chrV 11,093,039	contains similarity to Pfam domain PF01433 Peptidase family M1 contains similarity to Interpro domains IPR014782 (Peptidase M1, membrane alanine aminopeptidase, N-terminal), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001930 (Peptidase M1, membrane alanine aminopeptidase)
45	F40G9.8	F40G9.8	n/a	chrIII 164,235
46	C02B8.3	C02B8.3	n/a	chrX 8,139,820
47	bbs-8	T25F10.5	n/a	chrV 6,763,757	bbs-8 encodes a tetratricopeptide repeat (TPR)-containing protein that is orthologous to the human Bardet-Biedl syndrome protein, BBS8; in C. elegans, bbs-8 activity is required for cilia biogenesis and function; accordingly, bbs-8 mutant animals display odorant chemotaxis defects and exhibit both aberrant motility and abnormal localization of at least two intraflagellar transport (IFT) protein markers; a BBS-8::GFP translational fusion is expressed exclusively in ciliated head and tail neurons, where it localizes predominantly to the base of cilia, known as the ciliary transition zone; BBS-8::GFP is also observed moving bidirectionally (anterograde and retrograde) along the ciliary axoneme; DNA sequences upstream of bbs-8 contain X box DNA binding sites, suggesting that bbs-8 expression may be regulated by the DAF-19 RFX-type transcription factor.
48	C34D1.4	C34D1.4	n/a	chrV 13,258,178
49	T01G1.2	T01G1.2	n/a	chrIV 11,354,720	contains similarity to Escherichia coli HtrA suppressor protein (Protein prlF).; SW:SOHA_ECOLI
50	T17A3.10	T17A3.10	n/a	chrIII 155,573	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)