UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	set-19	W01C8.3	0	chrX 5,677,695	set-19 encodes a SET domain-containing protein; SET-19 has no non-nematode orthologs, but several paralogs (SET-6, SET-13, SET-15, SET-20, SET-21, and SET-32); neither set-19(ok1813) nor set-19(RNAi) have any obvious phenotypes.
2	C01G5.3	C01G5.3	n/a	chrIV 6,537,601	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
3	W02B8.4	W02B8.4	n/a	chrII 13,922,543	contains similarity to Pfam domain PF04870 Protein of unknown function, DUF644 contains similarity to Interpro domain IPR006954 (Protein of unknown function DUF644)
4	rab-14	K09A9.2	n/a	chrX 15,605,871	rab-14 encodes a member of the Rab GTPase family.
5	R13A1.1	R13A1.1	n/a	chrIV 7,220,097
6	srsx-14	C39H7.5	n/a	chrIV 5,625,990	C. elegans SRSX-14 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
7	T09B4.3	T09B4.3	n/a	chrI 6,177,087
8	eat-2	Y48B6A.4	n/a	chrII 14,169,168	eat-2 encodes a ligand-gated ion channel subunit most closely related to the non-alpha-subunits of nicotinic acetylcholine receptors (nAChR); EAT-2 functions postsynaptically in pharyngeal muscle to regulate the rate of pharyngeal pumping; eat-2 is also required for normal life span and defecation; a functional EAT-2::GFP fusion protein localizes to two small dots near the junction of pharyngeal muscles pm4 and pm5, which is the site of the posterior-most MC motor neuron processes and the MC synapse; eat-2 genetically interacts with eat-18, which encodes a predicted novel transmembrane protein expressed in pharyngeal muscle and required for proper function of pharyngeal nicotonic receptors.
9	R04A9.1	R04A9.1	n/a	chrX 405,128
10	mbk-1	T04C10.1	n/a	chrX 14,822,147	mbk-1 encodes a putative dual-specificity kinase (predicted to have both serine/threonine and tyrosine substrates) that is orthologous to Drosophila MINIBRAIN and mammalian DYRK1A/MnbK and that has a glutamine/asparagine-rich domain; MBK-1 is found in most or all nuclei, is dispensable for viability, and perturbs olfaction in AWC when overexpressed.
11	C36E8.4	C36E8.4	n/a	chrIII 4,014,026	contains similarity to Pfam domain PF00018 SH3 domain contains similarity to Interpro domains IPR001060 (Cdc15/Fes/CIP4), IPR001452 (Src homology-3)
12	D2005.6	D2005.6	n/a	chrI 7,790,102	contains similarity to Homo sapiens Fusion protein SYT-SSX1; ENSEMBL:ENSP00000269138
13	unc-9	R12H7.1	n/a	chrX 13,214,484	unc-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; UNC-9 is required for normal forward locomotion and egg-laying and also plays a role in the response to antihelminthics and volatile anesthetics; UNC-9 may form a functional pair with UNC-7, another C. elegans innexin, as mutations in unc-7 result in defects nearly identical to those in unc-9 mutant animals.
14	srj-20	Y45G12C.15	n/a	chrV 2,572,367	C. elegans SRJ-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	F15H9.1	F15H9.1	n/a	chrI 12,157,921	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
16	R04B3.1	R04B3.1	n/a	chrX 2,468,815	contains similarity to Interpro domain IPR000998 (MAM)
17	F09E8.1	F09E8.1	n/a	chrIV 13,141,838	contains similarity to Pfam domain PF01666 DX module contains similarity to Interpro domains IPR011052 (Proteinase and amylase inhibitor), IPR002593 (Protein of unknown function DX)
18	C38C3.7	C38C3.7	n/a	chrV 1,502,860	contains similarity to Pfam domains PF01827 (FTH domain) (2), PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
19	C06C3.9	C06C3.9	n/a	chrII 9,377,271
20	mlt-8	W08F4.6	n/a	chrII 570,690	mlt-8 encodes a novel protein; during development, mlt-8 activity is required for molting; a mlt-8::gfp reporter is expressed in hypodermal cells and in a single posterior neuron.
21	clec-141	EEED8.11	n/a	chrII 5,406,695	C. elegans CLEC-141 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
22	R05G6.1	R05G6.1	n/a	chrIV 7,539,920
23	srx-90	H12C20.5	n/a	chrV 11,581,770	C. elegans SRX-90 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
24	F45C12.9	F45C12.9	n/a	chrII 1,709,067	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
25	C41G7.7	C41G7.7	n/a	chrI 9,534,916	contains similarity to Plasmodium falciparum S-antigen (Fragment).; TR:Q9GZB4
26	F02E11.2	F02E11.2	n/a	chrII 3,267,119
27	srg-46	F32H5.5	n/a	chrV 13,364,203	C. elegans SRG-46 protein ;
28	F23H11.7	F23H11.7	n/a	chrIII 918,259
29	R01E6.7	R01E6.7	n/a	chrX 13,568,618	contains similarity to Ectocarpus siliculosus virus EsV-1-142.; TR:Q8QKY0
30	F44E7.7	F44E7.7	n/a	chrV 5,784,253	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
31	T11A5.1	T11A5.1	n/a	chrV 9,859,109	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR008162 (Inorganic pyrophosphatase)
32	T05C1.2	T05C1.2	n/a	chrII 4,482,363
33	flp-4	C18D1.3	n/a	chrII 10,054,913	C. elegans FLP-4 protein ;
34	F28B4.1	F28B4.1	n/a	chrX 3,205,615
35	fbxb-1	T26H2.1	n/a	chrV 19,240,953	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
36	ZK1290.10	ZK1290.10	n/a	chrII 7,552,859	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003582 (Metridin-like ShK toxin)
37	Y17G7B.19	Y17G7B.19	n/a	chrII 12,110,327	contains similarity to Pfam domain PF01666 (DX module)
38	C44B11.1	C44B11.1	n/a	chrIII 3,156,820	contains similarity to Pfam domain PF06905 Fas apoptotic inhibitory molecule (FAIM1) contains similarity to Interpro domain IPR010695 (Fas apoptotic inhibitory molecule)
39	M70.4	M70.4	n/a	chrIV 2,258,333	M70.4 is orthologous to human O-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE (FLJ20277; OMIM:606822), which when mutated leads to muscle-eye-brain disease.
40	C10A4.1	C10A4.1	n/a	chrX 7,417,182	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domain IPR008906 (HAT dimerisation)
41	F29A7.3	F29A7.3	n/a	chrII 2,753,579	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
42	abt-3	F55G11.9	n/a	chrIV 12,953,691	abt-3 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-3 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of abt-3 activity via RNAi results in no obvious defects, the precise role of abt-3 in C. elegans development and/or behavior is not yet known.
43	Y48E1C.3	Y48E1C.3	n/a	chrII 13,439,410	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
44	grl-2	T16G1.8	n/a	chrV 12,945,836	grl-2 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-2 is expressed in neurons, amphid socket cells, and other cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
45	F21C3.6	F21C3.6	n/a	chrI 7,284,859	contains similarity to Homo sapiens Isoform 1 of Caldesmon; ENSEMBL:ENSP00000354826
46	F16D3.6	F16D3.6	n/a	chrI 8,376,505	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR010601 (Protein of unknown function DUF1182)
47	K05F1.5	K05F1.5	n/a	chrII 5,791,755	contains similarity to Pfam domain PF01551 Peptidase family M23 contains similarity to Interpro domains IPR016047 (Peptidase M23), IPR008663 (Leukocyte cell-derived chemotaxin 2), IPR011055 (Duplicated hybrid motif)
48	C56G2.5	C56G2.5	n/a	chrIII 6,323,209	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR008973 (C2 calcium/lipid-binding region, CaLB)
49	4R79.2	4R79.2	n/a	chrIV 17,481,819	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR006688 (ADP-ribosylation factor), IPR002041 (Ran GTPase), IPR013753 (Ras), IPR006687 (GTP-binding protein SAR1), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR005225 (Small GTP-binding protein), IPR003579 (Ras small GTPase, Rab type)
50	ins-39	F21E9.4	n/a	chrX 1,344,119	ins-39 encodes an insulin-like peptide.