UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	VW02B12L.2	VW02B12L.2	1e-67	chrII 11,439,443	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C39E9.7	C39E9.7	n/a	chrIV 13,074,688	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
4	F22H10.5	F22H10.5	n/a	chrX 16,687,280	contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
5	srm-1	T28H11.2	n/a	chrIV 5,013,566	C. elegans SRM-1 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001991 (Sodium:dicarboxylate symporter)
6	T08A9.5	T08A9.5	n/a	chrX 7,312,937
7	soc-1	F41F3.2	n/a	chrV 4,644,923	C. elegans SOC-1 protein; contains similarity to Pfam domain PF00169 PH domain contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type)
8	srh-15	C50B6.6	n/a	chrV 13,321,651	C. elegans SRH-15 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	F56A8.1	F56A8.1	n/a	chrIII 13,252,041	contains similarity to Pfam domain PF04547 Protein of unknown function, DUF590 contains similarity to Interpro domain IPR007632 (Protein of unknown function DUF590)
10	srh-268	C54F6.1	n/a	chrV 7,540,084	C. elegans SRH-268 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	fpn-1.3	R08F11.6	n/a	chrV 3,796,213	C. elegans FPN-1.3 protein; contains similarity to Pfam domain PF06963 Ferroportin1 (FPN1) contains similarity to Interpro domains IPR009716 (Ferroportin1), IPR016196 (MFS general substrate transporter)
12	B0041.3	B0041.3	n/a	chrI 4,645,153	contains similarity to Pfam domain PF01476 LysM domain contains similarity to Interpro domain IPR002482 (Peptidoglycan-binding LysM)
13	ceh-1	F16H11.4	n/a	chrX 4,653,768	ceh-1 encodes a protein that contains a homeobox domain.
14	M04C9.4	M04C9.4	n/a	chrI 9,356,115	contains similarity to Bos taurus Osteopontin precursor (Bone sialoprotein 1).; SW:OSTP_BOVIN
15	Y37E11B.6	Y37E11B.6	n/a	chrIV 3,598,943	Y37E11B.6 encodes an ortholog of Rpp21 (Rpr2), a protein subunit of the endoribonuclease RNAse P, which cleaves tRNA precursors to produce their mature 5' end.
16	F38A1.6	F38A1.6	n/a	chrIV 1,252,165
17	T22F3.10	T22F3.10	n/a	chrV 3,608,429	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
18	tsp-11	B0563.2	n/a	chrX 9,164,502	C. elegans TSP-11 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
19	C07D8.2	C07D8.2	n/a	chrX 7,362,559	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
20	srh-8	K09D9.8	n/a	chrV 4,006,527	C. elegans SRH-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR005394 (P2Y12 purinoceptor)
21	tbx-8	T07C4.2	n/a	chrIII 10,348,548	C. elegans TBX-8 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR000694 (Proline-rich region), IPR001699 (Transcription factor, T-box)
22	ZK637.2	ZK637.2	n/a	chrIII 8,888,857	contains similarity to Pfam domain PF05811 Eukaryotic protein of unknown function (DUF842) contains similarity to Interpro domain IPR008560 (Protein of unknown function DUF842, eukaryotic)
23	nas-1	F45G2.1	n/a	chrIII 13,407,525	nas-1 encodes an astacin-like metalloprotease.
24	clec-178	T19E7.1	n/a	chrIV 5,654,480	C. elegans CLEC-178 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
25	H22K11.3	H22K11.3	n/a	chrX 6,783,682	contains similarity to Candida albicans Hyphally-regulated protein precursor.; SW:P46591
26	F54A5.2	F54A5.2	n/a	chrI 966,565	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
27	tor-2	Y37A1B.13	n/a	chrIV 13,983,393	tor-2 encodes a AAA ATPase that, along with TOR-1 and OOC-5, comprise the three C. elegans orthologs of human torsinA, mutations in which are associated with torsion dystonia (OMIM:605204); overexpression of TOR-2 in nematodes with polyglutamine repeat-induced protein aggregates indicates that TOR-2 can suppress protein aggregation, suggesting TOR-2 may play a role in regulation of protein folding; in wild-type animals, TOR-2 localizes to the endoplasmic reticulum; in animals containing polyglutamine protein aggregates, TOR-2 localizes to these sites of protein aggregation.
28	R06B9.4	R06B9.4	n/a	chrII 13,754,197	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
29	C08H9.1	C08H9.1	n/a	chrII 9,876,448	contains similarity to Pfam domain PF00450 Serine carboxypeptidase contains similarity to Interpro domain IPR001563 (Peptidase S10, serine carboxypeptidase)
30	rog-1	F54D12.6	n/a	chrII 1,374,343	rog-1 encodes a protein with an insulin receptor substrate-1 (IRS-type) phosphotyrosine-binding (PTB) domain that is required for the progression from pachytene to diakinesis in meiosis; rog-1 is primarily transcribed in germ cells, and this expression is required for oocyte development; ROG-1 is orthologous to human FRS2 (OMIM:607743) and FRS3 (OMIM:607744); rog-1(tm1031) mutant oocytes fail to progress from pachytene to diakinesis, a phenotype reminiscent of let-60 or mpk-1 mutant oocytes, and rog-1(tm1031) gonads lack phosphorylated MPK-1; rog-1(tm1031) and rog-1(RNAi) hermaphrodites show reduced brood sizes and increased embryonic lethality, with rog-1(tm1031) being more phenotypically severe than rog-1(RNAi); rog-1(tm1031) germ cell, brood size, and MPK-1 phosphorylation phenotypes are suppressed by the gain-of-function mutations let-60(n1046) or let-60(ga89ts); during meiosis, ROG-1 may function as an adaptor downstream of LET-23 and upstream of LET-60.
31	R10E12.2	R10E12.2	n/a	chrIII 9,968,408	contains similarity to Homo sapiens Splice isoform 1 of Q96PV0 Ras GTPase-activating protein SynGAP; ENSEMBL:ENSP00000293748
32	Y17D7C.2	Y17D7C.2	n/a	chrV 18,717,931	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
33	srh-200	F07C4.13	n/a	chrV 7,652,983	C. elegans SRH-200 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	C11D2.2	C11D2.2	n/a	chrIV 6,187,162	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001461 (Peptidase A1)
35	C33D12.2	C33D12.2	n/a	chrX 3,043,877	C33D12.2 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C01H6.6, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C33D12.2 may participate in metal homoeostasis; C33D12.2 is expressed in intestine, body wall muscle, nervous system (including ventral and dorsal nerve cords and head neurons), and adult vulval muscle and reproductive system; C33D12.2, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C33D12.2 has no obvious function in RNAi assays.
36	B0524.6	B0524.6	n/a	chrIII 1,903,905
37	cdh-1	R10F2.1	n/a	chrIII 2,923,253	cdh-1 encodes a cadherin that is similar, in the extracellular domain, to the Drosophila cadherin Dachsous (Ds); although the precise role of cdh-1 in C. elegans development and/or behavior is not yet known, loss of cdh-1 activity via RNAi using the hypersensitive rrf-3 strain can result in locomotion and growth defects, as well as larval lethality.
38	str-178	R11D1.5	n/a	chrV 12,715,427	C. elegans STR-178 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	T20F7.5	T20F7.5	n/a	chrX 16,850,352	contains similarity to Interpro domain IPR000694 (Proline-rich region)
40	F52D1.2	F52D1.2	n/a	chrX 447,631
41	nhr-116	F09C6.9	n/a	chrV 16,913,761	C. elegans NHR-116 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
42	F33H12.1	F33H12.1	n/a	chrII 2,601,167	contains similarity to Pfam domain PF00533 BRCA1 C Terminus (BRCT) domain contains similarity to Interpro domain IPR001357 (BRCT)
43	ZC373.5	ZC373.5	n/a	chrX 10,073,415	contains similarity to Pfam domain PF00596 Class II Aldolase and Adducin N-terminal domain contains similarity to Interpro domain IPR001303 (Class II aldolase/adducin, N-terminal)
44	smf-2	K11G12.3	n/a	chrX 6,717,366	C. elegans SMF-2 protein; contains similarity to Pfam domain PF01566 Natural resistance-associated macrophage protein contains similarity to Interpro domain IPR001046 (Natural resistance-associated macrophage protein)
45	F55H12.3	F55H12.3	n/a	chrI 8,884,703	contains similarity to Pfam domains PF00008 (EGF-like domain) (5), PF07645 (Calcium binding EGF domain) , PF07699 (GCC2 and GCC3) (3), PF07974 (EGF-like domain) (5), PF00057 (Low-density lipoprotein receptor domain class A) , PF02494 (HYR domain) , PF00084 (Sushi domain (SCR repeat)) (2)contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR011641 (GCC2 and GCC3), IPR016187 (C-type lectin fold), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding), IPR008985 (Concanavalin A-like lectin/glucanase)
46	F54D8.6	F54D8.6	n/a	chrIII 5,104,430	contains similarity to Interpro domain IPR000694 (Proline-rich region)
47	cyp-13A12	F14F7.3	n/a	chrIII 13,026,202	C. elegans CYP-13A12 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
48	ZK938.3	ZK938.3	n/a	chrII 9,832,928	contains similarity to Pfam domain PF00612 IQ calmodulin-binding motif contains similarity to Interpro domain IPR000048 (IQ calmodulin-binding region)
49	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
50	srg-33	F21F8.1	n/a	chrV 8,292,769	C. elegans SRG-33 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)