UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T28C6.3	T28C6.3	8e-78	chrIV 8,820,742	contains similarity to Homo sapiens HIV Tat-specific factor 1; ENSEMBL:ENSP00000218364
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C08F1.6	C08F1.6	n/a	chrII 1,787,707
4	fbxb-62	F55C9.8	n/a	chrV 19,301,505	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
5	F58E1.11	F58E1.11	n/a	chrII 1,692,234	contains similarity to Interpro domain IPR002034 (Alpha-isopropylmalate/homocitrate synthase, conserved site)
6	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
7	fbxb-103	F53C3.2	n/a	chrII 3,907,716	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
8	sdz-9	F08D12.10	n/a	chrII 2,773,000	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
9	acbp-6	Y17G7B.1	n/a	chrII 11,972,918	C. elegans ACBP-6 protein; contains similarity to Pfam domain PF00887 Acyl CoA binding protein contains similarity to Interpro domains IPR014352 (FERM/acyl-CoA-binding protein, 3-helical bundle), IPR000582 (Acyl-CoA-binding protein, ACBP)
10	fbxb-105	F08D12.8	n/a	chrII 2,770,341	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
11	hch-1	F40E10.1	n/a	chrX 14,698,114	hch-1 encodes a member of the zinc-dependent metalloprotease family that contains an epidermal growth factor-like domain, a CUB domain, and a TSP1 domain and affects hatching and QL neuroblast migration.
12	fbxb-57	F55C9.4	n/a	chrV 19,289,333	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
13	K08H10.9	K08H10.9	n/a	chrV 9,992,294	contains similarity to Pfam domain PF04051 Transport protein particle (TRAPP) component, Bet3 contains similarity to Interpro domain IPR007194 (Transport protein particle (TRAPP) component, Bet3)
14	dsl-1	W09G12.4	n/a	chrIV 1,207,661	dsl-1 encodes a secreted protein with a single DSL and EGF domain in series, resembling Delta/LAG-2; DSL-1, with APX-1 and LAG-2, is collectively required for LIN-12/Notch-mediated lateral signalling during postembryonic vulval development; DSL-1, when misexpressed by lag-2 sequences, can rescue the larval-lethal and anchor cell phenotypes of lag-2(q420ts); dsl-1(RNAi) animals have abnormal vulvae in a genetic background sensitized for lateral signalling defects; dsl-1(ok810) mutants, while viable and fertile, have a 4% penetrant defect in lateral signaling, which exceeds 13% with apx-1 and lag-2 RNAi; dsl-1 is strongly transcribed in P6.p cells; SUR-2 regulates dsl-1 along with apx-1 and lag-2; DSL-1 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-2, -3, -5, -6, and -7.
15	sdz-14	F14B6.1	n/a	chrI 12,216,990	C. elegans SDZ-14 protein ;
16	F45D3.1	F45D3.1	n/a	chrV 12,527,844	contains similarity to Schizosaccharomyces pombe Hypothetical 92.4 kDa protein C1685.14C in chromosome II.; TR:O74334
17	C28H8.1	C28H8.1	n/a	chrIII 5,926,486	C28H8.1 is orthologous to the human gene BCL7A (OMIM:601406), which when mutated leads to high-grade B-cell non-Hodgkin lymphoma.
18	F31D5.6	F31D5.6	n/a	chrII 4,211,553	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
19	fbxb-25	F58E1.2	n/a	chrII 1,684,456	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
20	taf-7.1	F54F7.1	n/a	chrX 11,836,759	The taf-7.1 gene encodes an ortholog of mammalian TATA-binding protein associated factor TAF7L (TAFIIQ, OMIM:300314) that in mice exhibits testis-specific expression; TAF-7 function in C. elegans is not yet known, as taf-7 inactivation by RNA interference does not result in any obvious developmental defects.
21	Y106G6H.9	Y106G6H.9	n/a	chrI 10,455,014	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
22	fbxb-117	F55C9.1	n/a	chrV 19,283,568	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
23	K03A11.1	K03A11.1	n/a	chrX 13,053,489	contains similarity to Interpro domain IPR001130 (Deoxyribonuclease, TatD-related)
24	dct-13	Y116A8C.17	n/a	chrIV 17,024,680	Y116A8C.17 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of Y116A8C.17 is predicted to function as an RNA-binding protein.
25	F23D12.5	F23D12.5	n/a	chrX 14,450,814	F23D12.5 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase; F23D12.5 contains a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); F23D12.5 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes; however, F23D12.5 has no obvious function in mass RNAi assays.
26	K09E3.6	K09E3.6	n/a	chrX 17,114,487	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
27	T26E3.5	T26E3.5	n/a	chrI 12,663,411	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
28	fbxb-54	K05F6.7	n/a	chrII 1,555,788	C. elegans FBXB-54 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001404 (Heat shock protein Hsp90), IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
29	F55G7.2	F55G7.2	n/a	chrX 11,930,695	contains similarity to Pfam domain PF08123 Histone methylation protein DOT1 contains similarity to Interpro domain IPR013110 (Histone methylation DOT1)
30	pri-2	W02D9.1	n/a	chrI 12,530,247	pri-2 encodes a homolog of the DNA polymerase alpha-primase subunit C that is required in embryos for the normal timing of embryonic cell divisions (much as DIV-1 is) and for normal mitosis in the germline.
31	F55C9.3	F55C9.3	n/a	chrV 19,287,274	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
32	Y73C8C.8	Y73C8C.8	n/a	chrV 3,112,017	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
33	Y43F11A.4	Y43F11A.4	n/a	chrII 12,120,633	contains similarity to Bos taurus Phosphatidylinositol 3-kinase regulatory gamma subunit (PI3-kinasesp85-gamma subunit) (PtdIns-3-kinase p85-gamma) (p55PIK).; SW:P55G_BOVIN
34	T05D4.2	T05D4.2	n/a	chrIII 13,562,369	contains similarity to Mus musculus Similar to SPEER 2.; TR:Q80ZP2
35	C17E4.2	C17E4.2	n/a	chrI 9,413,650	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
36	mdt-31	F32H2.2	n/a	chrI 8,966,630	C. elegans MDT-31 protein; contains similarity to Pfam domain PF05669 SOH1 contains similarity to Interpro domain IPR008831 (SOH1)
37	C24H12.8	C24H12.8	n/a	chrII 422,729	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
38	srh-308	F58E10.6	n/a	chrV 14,016,755	C. elegans SRH-308 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	F27C1.4	F27C1.4	n/a	chrI 5,423,026
40	F58E1.12	F58E1.12	n/a	chrII 1,693,958
41	F31E8.4	F31E8.4	n/a	chrII 6,799,569	contains similarity to Pfam domain PF04145 Ctr copper transporter family contains similarity to Interpro domain IPR007274 (Ctr copper transporter)
42	C48B6.9	C48B6.9	n/a	chrI 6,924,938	contains similarity to Interpro domain IPR000366 (Fungal pheromone mating factor STE2 GPCR)
43	dsl-6	H02I12.4	n/a	chrIV 11,397,523	dsl-6 encodes a putative transmembrane protein whose extracellular domain has a single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-6 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
44	egl-26	C23H3.1	n/a	chrII 70,469	egl-26 encodes a protein that contains an H-box and an NC domain that is a member of the LRAT (lecithin retinol acyltransferase) subfamily of the NlpC/P60 superfamily of enzymes; egl-26 activity is required for fertility, egg laying, and vulval development, specifically the connection of the uterus to the vulva mediated by proper morphogenesis of vulF, the most dorsal vulval cell; EGL-26 is an apical membrane protein that is expressed in many cells, including vulF, and appears to be expressed near the vulva and uterus only during the L4 larval stage; EGL-26 membrane localization is necessary for its function.
45	M02D8.3	M02D8.3	n/a	chrX 8,734,954	contains similarity to Dictyostelium discoideum PHD Zn finger-containing protein.; TR:Q1ZXQ2
46	srx-73	F41F3.7	n/a	chrV 4,664,669	C. elegans SRX-73 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
47	ZK899.6	ZK899.6	n/a	chrX 9,463,973	contains similarity to Saccharomyces cerevisiae Delta-like subunit of the yeast AP-3 complex which functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function; SGD:YPL195W
48	R11.4	R11.4	n/a	chrX 16,210,394	contains similarity to Leishmania major Hypothetical protein.; TR:Q9GRL1
49	ZK1127.3	ZK1127.3	n/a	chrII 7,055,637	contains similarity to Pfam domain PF07904 CT20 family contains similarity to Interpro domain IPR012423 (CT20)
50	F44A6.3	F44A6.3	n/a	chrX 10,213,400	contains similarity to Human parainfluenza 1 virus RNA polymerase alpha subunit (EC 2.7.7.48) (Nucleocapsidsphosphoprotein).; SW:RRPP_PI1HB