UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxa-202	T28C12.3	0	chrV 6,328,019	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
2	C18E9.8	C18E9.8	n/a	chrII 8,986,939	C18E9.8 is orthologous to the human gene JOINED TO JAZF1 (JJAZ1; OMIM:606245), which when mutated leads to disease.
3	F49F1.12	F49F1.12	n/a	chrIV 4,142,374	contains similarity to Homo sapiens Putative uncharacterized protein (Fragment); ENSEMBL:ENSP00000333119
4	H32C10.3	H32C10.3	n/a	chrIV 5,918,692	contains similarity to Pfam domains PF00023 (Ankyrin repeat) (5), PF01529 (DHHC zinc finger domain) contains similarity to Interpro domains IPR001594 (Zinc finger, DHHC-type), IPR002110 (Ankyrin)
5	C04G2.2	C04G2.2	n/a	chrIV 10,091,506	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
6	C32H11.9	C32H11.9	n/a	chrIV 12,935,630	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
7	C27B7.6	C27B7.6	n/a	chrIV 8,904,670	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
8	ZC581.7	ZC581.7	n/a	chrI 6,661,388	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
9	B0334.10	B0334.10	n/a	chrII 11,518,945	contains similarity to Vaccinia virus TB17L.; TR:Q9JF36
10	K02F6.2	K02F6.2	n/a	chrII 2,552,853	contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001357 (BRCT)
11	Y45F10B.2	Y45F10B.2	n/a	chrIV 13,595,366	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_6700.; TR:Q98PP9
12	ncl-1	ZK112.2	n/a	chrIII 7,734,657	ncl-1 encodes a cytoplasmic B-box zinc finger protein that negatively regulates rRNA and 5S RNA transcription, nucleolus size, and body size; NCL-1 is orthologous to Drosophila BRAIN TUMOR (BRAT), and ncl-1 mutants can be rescued by brat transgenes; NCL-1 is required for the normally small size of neuronal, muscle, and hypodermal nucleoli, and is already active in 4-cell embryos; NCL-1 may be a repressor of RNA polymerase I and III transcription and an inhibitor of cell growth, based on mutant analysis; ncl-1 animals have much larger neuronal nucleoli than normal, somewhat larger muscle and hypodermal nucleoli, but essentially normal intestinal and germline nucleoli (the last of which are large even in wild-type animals); conversely, intestinal and germline cells have the lowest amounts of NCL-1 protein; ncl-1 animals are 9% larger, have 22% more protein and twice as much rRNA, and transcribe rRNA twice as much as wild-type worms; ncl-1 functions cell autonomously, and ncl-1 mutations suppress the tumorous germline phenotype of pro-1(na48) mutants.
13	K02F6.9	K02F6.9	n/a	chrII 2,560,754	K02F6.9 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; K02F6.9 has no clear orthologs in other organisms.
14	C48B6.4	C48B6.4	n/a	chrI 6,890,348	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
15	F54C8.1	F54C8.1	n/a	chrIII 9,440,304	contains similarity to Pfam domains PF00725 (3-hydroxyacyl-CoA dehydrogenase, C-terminal domain) , PF02737 (3-hydroxyacyl-CoA dehydrogenase, NAD binding domain) contains similarity to Interpro domains IPR008927 (6-phosphogluconate dehydrogenase, C-terminal-like), IPR006108 (3-hydroxyacyl-CoA dehydrogenase, C-terminal), IPR013328 (Dehydrogenase, multihelical), IPR006176 (3-hydroxyacyl-CoA dehydrogenase, NAD binding), IPR006180 (3-hydroxyacyl-CoA dehydrogenase, conserved site), IPR016040 (NAD(P)-binding), IPR006036 (Potassium uptake protein TrkA)
16	ZC412.5	ZC412.5	n/a	chrV 14,874,791
17	K03H1.9	K03H1.9	n/a	chrIII 9,941,014	contains similarity to Homo sapiens DAN15 protein; TR:Q99491
18	K08C9.1	K08C9.1	n/a	chrI 11,485,648
19	Y43F8A.2	Y43F8A.2	n/a	chrV 19,373,855	contains similarity to Homo sapiens Cytokine receptor common beta chain precursor; ENSEMBL:ENSP00000262825
20	F16G10.2	F16G10.2	n/a	chrII 2,375,633	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
21	W06F12.3	W06F12.3	n/a	chrIII 13,735,661	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
22	B0513.6	B0513.6	n/a	chrIV 13,855,821	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
23	C18H7.7	C18H7.7	n/a	chrIV 596,081
24	M05B5.3	M05B5.3	n/a	chrI 7,187,440	contains similarity to Homo sapiens Similar to Suppressor protein SRP40; VG:OTTHUMP00000170311
25	ZC262.4	ZC262.4	n/a	chrIII 8,333,867
26	C06A1.3	C06A1.3	n/a	chrII 10,573,080	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
27	K07F5.8	K07F5.8	n/a	chrIV 9,849,087	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
28	F26A1.4	F26A1.4	n/a	chrIII 4,818,558	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core)
29	R102.7	R102.7	n/a	chrIV 10,703,834
30	ech-3	F43H9.1	n/a	chrV 8,022,781	C. elegans ECH-3 protein; contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
31	C17C3.11	C17C3.11	n/a	chrII 5,538,392	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
32	tba-6	F32H2.9	n/a	chrI 8,996,289	C. elegans TBA-6 protein; contains similarity to Pfam domains PF00091 (Tubulin/FtsZ family, GTPase domain) , PF03953 (Tubulin/FtsZ family, C-terminal domain) contains similarity to Interpro domains IPR002454 (Gamma tubulin), IPR002452 (Alpha tubulin), IPR002453 (Beta tubulin), IPR000217 (Tubulin), IPR003008 (Tubulin/FtsZ, GTPase), IPR004057 (Epsilon tubulin), IPR002967 (Delta tubulin), IPR000158 (Cell division protein FtsZ, N-terminal), IPR008280 (Tubulin/FtsZ, C-terminal)
33	kin-26	T06C10.6	n/a	chrIV 7,876,748	C. elegans KIN-26 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
34	H08M01.1	H08M01.1	n/a	chrIV 13,835,341	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR003071 (Orphan nuclear receptor, HMR type)
35	F16G10.5	F16G10.5	n/a	chrII 2,368,093
36	spe-15	F47G6.4	n/a	chrI 1,456,004	spe-15 encodes an unconventional myosin, and is homologous to both Drosophila and mouse myosin VI; spe-15 was identified in screens for mutants that have defective spermatogenesis; spe-15 is required during the terminal stages of spermatogenesis for the asymmetric partitioning of organelles like the mitochondria and for the proper partitioning of specialized structures called the fibrous-body membranous organelles into the spermatid; mutant spe-15 spermatids contain actin filaments in contrast to wild-type which lack them; spe-15 is also required for the proper morphology and activation of the spermatid; the human gene MYOSIN VI (MYO6; OMIM:600970), when mutated leads to disease that affects hearing.
37	T05D4.5	T05D4.5	n/a	chrIII 13,582,099	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein), IPR000533 (Tropomyosin)
38	C49A1.2	C49A1.2	n/a	chrI 14,210,845	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
39	D2062.6	D2062.6	n/a	chrII 2,619,582	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
40	H06O01.4	H06O01.4	n/a	chrI 7,003,489	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
41	C15H11.1	C15H11.1	n/a	chrV 14,394,129	contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002394 (Nicotinic acetylcholine receptor, N-terminal), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
42	M110.7	M110.7	n/a	chrII 8,235,210	contains similarity to Pfam domain PF01237 Oxysterol-binding protein contains similarity to Interpro domain IPR000648 (Oxysterol-binding protein)
43	F26F2.1	F26F2.1	n/a	chrV 20,555,875	contains similarity to Drosophila melanogaster Flybase gene name is CG2839-PA;; FLYBASE:CG2839
44	F10E9.2	F10E9.2	n/a	chrIII 8,313,421	contains similarity to Interpro domain IPR001841 (Zinc finger, RING-type)
45	C48E7.8	C48E7.8	n/a	chrI 6,267,364	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
46	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
47	dlc-6	Y106G6G.3	n/a	chrI 10,323,861	dlc-6 encodes a putative dynein light chain 1; DLC-6 is orthologous to human DYNLL1 (OMIM:601562) and DYNLL2 (OMIM:608942), but much more divergent from them than its paralog DLC-1; DLC-6's other paralogs are DLC-2/-5; DLC-6 has no obvious function in mass RNAi assays.
48	ZK930.5	ZK930.5	n/a	chrII 11,882,963	contains similarity to Methanobacterium thermoautotrophicum Phosphoserine phosphatase.; TR:O27663
49	F55D12.6	F55D12.6	n/a	chrI 7,902,571	contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR001865 (Ribosomal protein S2), IPR001859 (Ribosomal protein P2), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal)
50	T19D12.5	T19D12.5	n/a	chrII 6,635,499	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)