UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ins-18	T28B8.2	5e-45	chrI 8,148,533	ins-18 encodes one of 40 C. elegans insulin/IGF-like peptides; INS-18, along with INS-1, are the only two C. elegans insulins that contain a C peptide, characteristic of mammalian insulins, connecting the B and A chains; overexpression of ins-18 induces dauer arrest at 26 degrees C and enhances the dauer arrest seen in a daf-2 mutant at 20 degrees C, suggesting that INS-18 functions to antagonize DAF-2 receptor signaling; ins-18::gfp reporters are expressed in neurons and the intestine.
2	far-3	F15B9.1	n/a	chrV 12,997,151	C. elegans FAR-3 protein; contains similarity to Pfam domain PF05823 Nematode fatty acid retinoid binding protein (Gp-FAR-1) contains similarity to Interpro domain IPR008632 (Nematode fatty acid retinoid binding)
3	C08E8.4	C08E8.4	n/a	chrV 18,372,276	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domain IPR012816 (Conserved hypothetical protein CHP02464)
4	nlp-8	D2005.2	n/a	chrI 7,801,131	C. elegans NLP-8 protein ;
5	flp-3	W07E11.2	n/a	chrX 10,092,469	flp-3 encodes nine copies of a GTMRFamide-containing peptide that is predicted to function as a neuropeptide that inhibits pharyngeal action potential in a manner similar to octopamine without having a significant effect on basal resting membrane potential; expressed in three pairs of neurons IL1D, OL1, URB.
6	nlp-14	D1009.4	n/a	chrX 8,918,369	C. elegans NLP-14 protein; contains similarity to Interpro domain IPR005829 (Sugar transporter, conserved site)
7	flp-5	C03G5.7	n/a	chrX 8,529,581	flp-5 encodes a predicted FMRFamide-like peptide neurotransmitter that increases action potential frequency in the pharyngeal muscle when applied to the pharynx of dissected worms; expressed in the sensory neurons ASE and PVM.
8	flp-21	C26F1.10	n/a	chrV 7,793,674	flp-21 encodes a single FMRFamide-related neuropeptide (FaRP) that serves as a ligand for NPR-1, a G protein-coupled receptor that regulates social versus solitary feeding behavior in several Caenorhabditis species; genetic analysis suggests that FLP-21 acts through NPR-1 to inhibit social feeding behavior; FLP-21 is expressed in the ADL, ASE and ASH sensory neurons, the URA motor neurons, the MC, M2 and M4 pharyngeal neurons, and the intestine; flp-21 encodes the only FMRFamide-related neuropeptide (FaRP) encoded by the C. elegans genome that activates both the social (215F) and the solitary (215V) forms of NPR-1 in both Xenopus oocytes and pharyngeal assays.
9	F52E1.8	F52E1.8	n/a	chrV 8,393,368	contains similarity to Pfam domains PF00300 (Phosphoglycerate mutase family) , PF00328 (Histidine acid phosphatase) contains similarity to Interpro domains IPR000560 (Histidine acid phosphatase), IPR013078 (Phosphoglycerate mutase)
10	drn-1	C54A12.4	n/a	chrII 5,271,026	C. elegans DRN-1 protein; contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
11	F20A1.10	F20A1.10	n/a	chrV 7,052,940
12	fipr-22	C37A5.2	n/a	chrI 14,155,893	C. elegans FIPR-22 protein ; contains similarity to Homo sapiens Keratin-associated protein 20-2; ENSEMBL:ENSP00000330746
13	C10G11.1	C10G11.1	n/a	chrI 6,307,930
14	F42C5.3	F42C5.3	n/a	chrIV 7,286,758	contains similarity to Homo sapiens Intersectin 1 short form transcript variant 8; ENSEMBL:ENSP00000370685
15	ttr-29	R90.4	n/a	chrV 12,906,429	C. elegans TTR-29 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
16	M04D8.7	M04D8.7	n/a	chrIII 10,037,728	contains similarity to Sulfolobus tokodaii Putative cytochrome o ubiquinol oxidase assembly factor.; TR:Q970T4
17	T07D1.3	T07D1.3	n/a	chrX 2,443,181	contains similarity to Interpro domain IPR016160 (Aldehyde dehydrogenase, conserved site)
18	cal-2	C18E9.1	n/a	chrII 8,961,053	cal-2 encodes a calmodulin homolog required for embryonic development or viability; CAL-2 is closely similar to its paralogs CAL-1, CAL-3, CAL-4 and CMD-1.
19	T26G10.5	T26G10.5	n/a	chrIII 9,426,015	contains similarity to Streptococcus pyogenes Hypothetical protein SPy0952.; TR:Q9A032
20	flp-19	M79.4	n/a	chrX 10,605,248	C. elegans FLP-19 protein ;
21	nlp-37	F48B9.4	n/a	chrX 2,163,570	C. elegans NLP-37 protein ;
22	K02A6.2	K02A6.2	n/a	chrX 8,224,536
23	nlp-1	C01C4.1	n/a	chrX 3,727,992	nlp-1 encodes a predicted neuropeptide-like protein of the MSFamide family with similarity to Aplysia californica (sea hare) buccalin, a neuropeptide that regulates acetylcholine-induced muscle contraction; NLP-1 is expressed in the phasmid PHB tail sensory neuron, lateral neurons, head neurons, and the intestine; the precise role of NLP-1 in nervous system function and development is not yet known.
24	E02A10.3	E02A10.3	n/a	chrV 12,586,524	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000261 (EPS15 homology (EH))
25	ZC204.1	ZC204.1	n/a	chrII 1,666,906	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
26	C07A12.2	C07A12.2	n/a	chrX 4,545,119
27	T10G3.1	T10G3.1	n/a	chrV 13,471,322	contains similarity to Saccharomyces cerevisiae interacts with Sin1p; SGD:YER047C
28	F57H12.4	F57H12.4	n/a	chrIV 7,971,993	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR001920 (Asp/Glu racemase), IPR009126 (Cholecystokinin receptor), IPR000276 (GPCR, rhodopsin-like)
29	F14D7.8	F14D7.8	n/a	chrV 14,312,353	contains similarity to Staphylococcus epidermidis Conserved hypothetical protein.; TR:Q8CSE5
30	C15B12.4	C15B12.4	n/a	chrX 6,472,014	contains similarity to Interpro domain IPR000158 (Cell division protein FtsZ, N-terminal)
31	tsp-1	C02F5.8	n/a	chrIII 8,238,638	C. elegans TSP-1 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin), IPR013305 (ABC transporter, ABCB2), IPR003091 (Voltage-dependent potassium channel)
32	M7.8	M7.8	n/a	chrIV 11,094,455	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
33	zig-5	Y48A6A.1	n/a	chrIII 10,952,247	zig-5 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-5::gfp reporter fusion is expressed in a number of neurons, including PVT, VD1-13, RID, AFD, ASK, RIV, RIB, PVQ, DVA, and RIS; zig-5::gfp is detected in the PVT neuron beginning at the three-fold stage of embryogenesis and continuing throughout larval development; loss of zig-5 activity in large-scale RNAi screens has been reported to result in low levels of embryonic lethality.
34	F47E1.2	F47E1.2	n/a	chrX 9,059,694	contains similarity to Pfam domain PF03137 Organic Anion Transporter Polypeptide (OATP) family contains similarity to Interpro domains IPR004156 (Organic anion transporter polypeptide OATP), IPR016196 (MFS general substrate transporter)
35	Y43F8C.5	Y43F8C.5	n/a	chrV 19,631,978	contains similarity to Dictyostelium discoideum Myb-like protein (Fragment).; SW:MYBH_DICDI
36	F21F3.1	F21F3.1	n/a	chrI 4,909,304	contains similarity to Pfam domain PF01436 NHL repeat contains similarity to Interpro domains IPR000720 (Peptidyl-glycine alpha-amidating monooxygenase), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013017 (NHL repeat, subgroup), IPR015943 (WD40/YVTN repeat-like), IPR001258 (NHL repeat)
37	C17G10.7	C17G10.7	n/a	chrII 5,607,281
38	nlp-3	F48C11.3	n/a	chrX 13,178,076	nlp-3 encodes a neuropeptide-like protein of the GFxGF family with similarity to orcokinins, highly conserved peptides native to crustaceans that enhance hindgut contractions; NLP-3 is expressed in neurons in the head, pharynx, and vulva, and in the intestine; the precise role of NLP-3 in nervous system function and development is not yet clear.
39	F20B6.6	F20B6.6	n/a	chrX 4,201,908	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
40	far-4	F15B9.2	n/a	chrV 12,999,023	far-4 encodes a fatty acid and retinol-binding protein, paralogous to FAR-3 and FAR-5 and distantly homologous to FAR proteins of parasitic nematodes; FAR-4 binds lipids in vitro; far-4 is transcribed at highest levels in the fourth larval stage, and is dispensable for viability and gross morphology in mass RNAi assays.
41	M60.7	M60.7	n/a	chrX 8,259,771	contains similarity to Pfam domains PF07525 (SOCS box) , PF00023 (Ankyrin repeat) (9)contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001496 (SOCS protein, C-terminal)
42	C02B8.3	C02B8.3	n/a	chrX 8,139,820
43	K11D12.8	K11D12.8	n/a	chrV 5,040,194
44	T28H10.3	T28H10.3	n/a	chrV 12,513,961	contains similarity to Pfam domain PF01650 Peptidase C13 family contains similarity to Interpro domain IPR001096 (Peptidase C13, legumain)
45	F41G4.8	F41G4.8	n/a	chrX 16,844,106
46	C31H5.5	C31H5.5	n/a	chrI 9,048,863	contains similarity to Mus musculus Eukaryotic translation initiation factor 2 subunit 2 (Eukaryoticstranslation initiation factor 2 beta subunit) (eIF-2-beta).; SW:IF2B_MOUSE
47	flp-7	F49E10.3	n/a	chrX 5,886,304	flp-7 encodes an MVRFamide-containing peptide that, upon injection into A. suum, produces paralysis and loss of locomotory waveforms, increased body length, and decreased cAMP production.
48	flp-24	C24A1.1	n/a	chrIII 725,550	C. elegans FLP-24 protein ;
49	K07A1.3	K07A1.3	n/a	chrI 9,587,656	contains similarity to Pfam domain PF03412 Peptidase C39 family contains similarity to Interpro domain IPR005074 (Peptidase C39, bacteriocin processing)
50	F13D12.3	F13D12.3	n/a	chrII 11,721,323	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)