UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T25F10.4	T25F10.4	0	chrV 6,761,420	contains similarity to Interpro domain IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
2	F26A1.6	F26A1.6	n/a	chrIII 4,816,522	contains similarity to Lumbricus rubellus Amine oxidase-like protein (Fragment).; TR:Q94610
3	F59D6.4	F59D6.4	n/a	chrV 3,030,897	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
4	srb-1	C27D6.10	n/a	chrII 5,170,361	C. elegans SRB-1 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
5	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
6	B0496.1	B0496.1	n/a	chrIV 7,446,888	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR000210 (BTB/POZ-like)
7	D2089.3	D2089.3	n/a	chrII 10,663,519	contains similarity to Homo sapiens hypothetical protein LOC150383; ENSEMBL:ENSP00000325301
8	srbc-11	C18B10.1	n/a	chrV 7,494,565	C. elegans SRBC-11 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
9	T11G6.5	T11G6.5	n/a	chrIV 10,839,263	contains similarity to Interpro domain IPR000694 (Proline-rich region)
10	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
11	insc-1	F43E2.3	n/a	chrII 7,361,541	C. elegans INSC-1 protein; contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000225 (Armadillo), IPR016024 (Armadillo-type fold)
12	F14F9.6	F14F9.6	n/a	chrV 5,148,306
13	nhr-159	C17E7.7	n/a	chrV 3,876,286	C. elegans NHR-159 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
14	nhr-223	T26E4.8	n/a	chrV 15,796,934	C. elegans NHR-223 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
15	C56A3.3	C56A3.3	n/a	chrV 13,533,300	C56A3.3 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that C56A3.3 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
16	str-63	C17B7.1	n/a	chrV 3,352,167	C. elegans STR-63 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	Y56A3A.30	Y56A3A.30	n/a	chrIII 11,976,478	contains similarity to Drosophila melanogaster Flybase gene name is CG6004-PB;; FLYBASE:CG6004
18	srw-113	ZK1037.9	n/a	chrV 15,333,837	C. elegans SRW-113 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
19	srv-6	C52B9.5	n/a	chrX 4,258,053	C. elegans SRV-6 protein ;
20	F40H6.2	F40H6.2	n/a	chrIII 6,042,332
21	srz-70	C09G12.6	n/a	chrIV 3,478,198	C. elegans SRZ-70 protein ;
22	K10C9.4	K10C9.4	n/a	chrV 1,051,572	contains similarity to Interpro domain IPR003945 (NADH-plastoquinone oxidoreductase, chain 5)
23	him-14	ZK1127.11	n/a	chrII 7,067,448	him-14 encodes a germline-specific member of the MutS family of DNA mismatch repair (MMR) proteins that is orthologous to human MSH4 and Saccharomyces cerevisiae Msh4p; during the pachytene stage of meiosis, HIM-14 activity is required for promoting crossing over between homologous chromosomes and thus, for chiasmata formation and proper chromosome segregation; in contrast, HIM-14 activity does not appear to be required for mismatch repair, nor for chromosome pairing or synapsis; him-14 mRNA expression is detected exclusively in the germline.
24	W03G1.8	W03G1.8	n/a	chrIV 527,981
25	nhr-147	C03G6.8	n/a	chrV 7,347,394	C. elegans NHR-147 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
26	R10D12.6	R10D12.6	n/a	chrV 13,949,458	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
27	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
28	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
29	Y1A5A.2	Y1A5A.2	n/a	chrIII 3,984,495	contains similarity to Corynebacterium efficiens Putative nitrate transport protein.; TR:Q8FPW8
30	F41E7.6	F41E7.6	n/a	chrX 10,308,733	contains similarity to Pfam domain PF00755 Choline/Carnitine o-acyltransferase contains similarity to Interpro domain IPR000542 (Acyltransferase ChoActase/COT/CPT)
31	math-50	ZK250.8	n/a	chrII 1,957,153	math-50 encodes a protein which has a meprin-associated Traf homology (MATH) domain and may be involved in apoptosis.
32	F28D1.8	F28D1.8	n/a	chrIV 12,388,613	contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR007110 (Immunoglobulin-like), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR003599 (Immunoglobulin subtype)
33	str-264	C06B8.4	n/a	chrV 15,491,810	C. elegans STR-264 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	T10E10.4	T10E10.4	n/a	chrX 6,318,637	T10E10.4 encodes a large (966-residue) protein, predicted to be secreted, with two N-terminal chitin-binding peritrophin-A domains followed by 14 cysteine-rich domains and one C-terminal EB module; the general organization of T10E10.4 protein resembles that of K04H4.2; T10E10.4 has no obvious function in mass RNAi assays but, like CEJ-1 and CPG-2, might participate in chitin synthesis.
35	srxa-1	W07A8.1	n/a	chrV 20,728,034	C. elegans SRXA-1 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
36	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
37	K02E2.1	K02E2.1	n/a	chrV 20,348,590	contains similarity to Salmo salar NADH-ubiquinone oxidoreductase chain 2 (EC 1.6.5.3).; SW:NU2M_SALSA
38	K03E5.1	K03E5.1	n/a	chrI 3,431,349	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domains IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR000859 (CUB)
39	T25D1.2	T25D1.2	n/a	chrX 16,516,558	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domains IPR009667 (Protein of unknown function DUF1258), IPR011332 (Ribosomal protein, zinc-binding)
40	srh-296	Y94A7B.4	n/a	chrV 17,811,540	C. elegans SRH-296 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	wah-1	Y56A3A.32	n/a	chrIII 11,994,707	wah-1 encodes a putative flavin-adenine dinucleotide (FAD)-binding oxidoreductase orthologous to mammalian PDCD8 (AIF; OMIM:300169, mutated in Harlequin mice); WAH-1 is required for apoptotic DNA degratation, SCRM-1 phospholipid scramblase activity, phosphatidylserine exposure, rapid apoptosis during embryonic development, and rapid engulfment of apoptotic cells in the germline; WAH-1 is also required for normally rapid growth and large brood sizes, and has a subtle proapoptotic function revealed in ced-3 or ced-4 mutant backgrounds; WAH-1 is expressed in most, if not all, cells of embryos and larvae; WAH-1 is normally mitochondrial, but can be released into the cytosol and nucleus by EGL-1 and CED-3; residues 380-550 of WAH-1 specifically bind SCRM-1 in vitro, but not SCRM-2 through SCRM-4, and WAH-1 binding is required in liposomes for more than residual SCRM-1 activity; WAH-1 also binds and activates CPS-6, promoting apoptotic DNA degradation, and transgenic coexpression of WAH-1 with CPS-6 specifically induces ectopic CED-3-dependent apoptosis in touch receptor neurons; CPS-6 shares a genetic pathway with WAH-1, whereas CED-3, CED-4, CED-8, and NUC-1 act independently of it; WAH-1 is paralogous to C. elegans F20D6.11 and human AIFM3 (AIFL).
42	C05C10.1	C05C10.1	n/a	chrII 9,918,735	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
43	F26C11.3	F26C11.3	n/a	chrII 9,906,024	contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
44	hyl-2	K02G10.6	n/a	chrX 4,698,095	hyl-2 encodes a predicted transmembrane protein that is related to Saccharomyces cerevisiae LAG1 (longevity assurance gene), a protein preferentially expressed in young yeasts; by homology, HYL-2 is predicted to have several possible functions, including regulation of lipid, particularly ceramide, biosynthesis, regulation of lipid transport, and regulation of protein translocation in the endoplasmic reticulum ; however, as loss of hyl-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of hyl-2 in C. elegans development and/or behavior is not yet known.
45	F28G4.5	F28G4.5	n/a	chrV 16,290,444	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
46	elks-1	F42A6.9	n/a	chrIV 3,346,268	elks-1 encodes the C. elegans homolog of the vertebrate ELKS (glutamine, leucine, lysine, and serine-rich) proteins; although loss of elks-1 activity results in no obvious developmental or behavioral abnormalities, the ELKS-1 C-terminus interacts with the PDZ domain of UNC-10/RIM in vitro, and in vivo each protein appears to play a nonessential role in localizing the other to the presynaptic active zone; in addition to the active zone, ELKS-1 also localizes to the pharyngeal basal lamina.
47	T08G5.9	T08G5.9	n/a	chrV 14,045,861	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
48	Y45G12C.11	Y45G12C.11	n/a	chrV 2,551,494	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
49	C18H7.1	C18H7.1	n/a	chrIV 618,237	contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domain IPR002035 (von Willebrand factor, type A)
50	nph-4	R13H4.1	n/a	chrV 11,837,428	nph-4 encodes an ortholog of human NPHP4 (OMIM:607215, mutated in juvenile nephronophthisis and Senior-Loken syndrome-4) that is required for normal chemotaxis, lifespan, and male mating behavior; NPH-4 is expressed in diverse neurons (amphid and phasmid sensory, URX, labial, male lumbar and cloacal ganglia, and male-specific CEM, HOB and RnB); within neurons, NPH-4 is a ciliary protein, localized to the transistion zone at cilial bases rather than ciliary axonemes, and absent from somata, axons, or dendrites; NPH-4 colocalizes with NPH-1 and PKD-2 in male-specific sensory cilia, and is required for the normal ciliary localization of NPH-1; NPH-4 expression requires DAF-19, and mutating an X-box in nph-4's promoter abolishes nph-4 expression; NPH-4 is required for NPH-1's localization to transistion zones; morphologically, nph-4 mutant cilia are normal, indicating a function for NPH-4 in signal transduction.