UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	dbl-1	T25F10.2	0	chrV 6,759,095	dbl-1 encodes a member of the transforming growth factor beta (TGFbeta) superfamily that includes Drosophila decapentaplegic (Dpp) and the vertebrate bone morphogenetic proteins (BMPs); DBL-1 functions as a dose-dependent ligand for the SMA-6 and DAF-4 TGFbeta receptors that ultimately activate the SMA-2, -3, and -4 complex of transcription factors to regulate body length and size, as well as the patterning of male sensory rays and copulatory spicules; DBL-1 signaling upregulates sma-6 expression, suggesting that there is positive autoregulation in the DBL-1 signaling pathway; in contrast, DBL-1 negatively regulates expression of LON-1, a predicted secreted protein that is a downstream component of the body size pathway; DBL-1 is expressed primarily in neurons.
2	F56H6.3	F56H6.3	n/a	chrI 12,289,861
3	F55E10.1	F55E10.1	n/a	chrX 8,342,071
4	ZK380.4	ZK380.4	n/a	chrX 1,652,654
5	C30H6.9	C30H6.9	n/a	chrIV 17,379,717	contains similarity to Bacillus anthracis Hypothetical protein.; TR:Q81PV8
6	taf-9	T12D8.7	n/a	chrIII 13,624,992	C. elegans TAF-9 protein; contains similarity to Pfam domain PF02291 Transcription initiation factor IID, 31kD subunit contains similarity to Interpro domains IPR003162 (Transcription factor TAFII-31), IPR009072 (Histone-fold)
7	sri-7	T06E6.4	n/a	chrV 15,401,049	C. elegans SRI-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
8	K04E7.1	K04E7.1	n/a	chrX 6,462,585
9	C34D4.10	C34D4.10	n/a	chrIV 7,120,692
10	ZC412.8	ZC412.8	n/a	chrV 14,879,632	contains similarity to Plasmodium cynomolgi Circumsporozoite protein precursor (CS).; SW:P08675
11	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
12	nhr-33	ZK455.6	n/a	chrX 11,319,573	C. elegans NHR-33 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
13	C01F6.1	C01F6.1	n/a	chrIV 9,098,665	C01F6.1 encodes a putative calcium-dependent phospholipid binding protein of the copine family; C01F6.1 is required for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; C01F6.1(RNAi) hermaphrodites are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them.
14	F08D12.4	F08D12.4	n/a	chrII 2,778,750	contains similarity to Interpro domain IPR016187 (C-type lectin fold)
15	srj-7	T28A11.10	n/a	chrV 3,245,861	C. elegans SRJ-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	D1014.2	D1014.2	n/a	chrV 8,145,287	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
17	F14F9.3	F14F9.3	n/a	chrV 5,139,826	contains similarity to Interpro domain IPR002867 (Zinc finger, C6HC-type)
18	C50F4.14	C50F4.14	n/a	chrV 9,548,707	The C50F4.14 gene encodes a putative GDP-fucose transporter orthologous to the human GDP-FUCOSE TRANSPORTER 1 gene (LAD II; OMIM:605881), which when mutated leads to congenital disorder of glycosylation, type IIc.
19	srw-111	M01G12.4	n/a	chrI 12,124,188	C. elegans SRW-111 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
20	srh-72	ZC204.5	n/a	chrII 1,639,907	C. elegans SRH-72 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	C47F8.4	C47F8.4	n/a	chrI 12,317,914	contains similarity to Pfam domain PF03360 Glycosyltransferase family 43 contains similarity to Interpro domain IPR005027 (Glycosyl transferase, family 43)
22	srx-135	F09F3.11	n/a	chrV 13,860,290	C. elegans SRX-135 protein ;
23	C28A5.5	C28A5.5	n/a	chrIII 4,451,510	contains similarity to Petunia hybrida PGPS/D8.; TR:Q9ZTN1
24	F28A10.5	F28A10.5	n/a	chrII 850,172	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
25	sru-2	C33A12.13	n/a	chrIV 9,486,898	C. elegans SRU-2 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
26	lgc-7	Y57G11C.2	n/a	chrIV 14,712,127	C. elegans LGC-7 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
27	M03F8.5	M03F8.5	n/a	chrV 5,935,209	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domain IPR004245 (Protein of unknown function DUF229)
28	fbxa-89	Y75B8A.21	n/a	chrIII 12,237,580	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
29	rap-1	C27B7.8	n/a	chrIV 8,917,869	rap-1 encodes a member of the Ras superfamily of small GTPases; the activated protein interacts with W05B10.4 and T14G10.2 in yeast two-hybrid assays and rap-1 is expressed in some neurons in the head and tail, the rectal epithelial cells, body muscle, hypodermis, and in the somatic cells of the gonad.
30	fbxa-168	C31C9.4	n/a	chrII 13,647,223	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
31	K03D7.9	K03D7.9	n/a	chrV 17,488,056	contains similarity to Homo sapiens Olfactory receptor 1A1; ENSEMBL:ENSP00000305207
32	srb-3	C27D6.8	n/a	chrII 5,166,058	C. elegans SRB-3 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
33	F20B4.2	F20B4.2	n/a	chrX 17,704,274
34	T01D3.2	T01D3.2	n/a	chrV 13,706,650	contains similarity to Pfam domain PF00989 PAS fold contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR013767 (PAS fold), IPR000014 (PAS), IPR011598 (Helix-loop-helix DNA-binding), IPR001067 (Nuclear translocator)
35	sra-24	T06G6.2	n/a	chrI 12,706,029	C. elegans SRA-24 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
36	H08J19.1	H08J19.1	n/a	chrX 15,643,559	contains similarity to Homo sapiens formin-like 3 isoform 1; ENSEMBL:ENSP00000335655
37	mlt-4	ZC15.7	n/a	chrV 20,280,792	mlt-4 encodes a homolog of human INVS (inversin, OMIM:243305; mutated in nephronophthisis) that has no function in mass RNAi assays.
38	F11D11.4	F11D11.4	n/a	chrV 18,762,417	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
39	F55E10.4	F55E10.4	n/a	chrX 8,327,670
40	R155.4	R155.4	n/a	chrIII 1,978,876	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR003125 (Protein of unknown function WSN), IPR005427 (Salmonella/Shigella invasin protein C)
41	F36A4.11	F36A4.11	n/a	chrIV 4,245,281
42	W04G5.5	W04G5.5	n/a	chrI 11,635,717	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
43	fbxa-100	F14H3.7	n/a	chrV 16,060,910	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
44	ace-2	Y44E3A.2	n/a	chrI 3,304,491	An acetylcholineesterase involved in the termination of cholinergic nerve transmission; it is predominantly expressed in motoneurons.
45	ces-1	F43G9.11	n/a	chrI 8,634,989	ces-1 encodes a C2H2-type zinc finger transcription factor that is a member of the Snail family of proteins that includes Drosophila Scratch, Snail, and Slug, and human SNAIL and SLUG; although the normal function of CES-1 is not fully understood, gain-of-function mutations indicate that CES-1 can function as a transcriptional repressor that blocks programmed cell death in specific neurons by inhibiting expression of the cell-death activator EGL-1; in regulating EGL-1 expression, CES-1 appears to antagonize the transcriptional activity of the bHLH proteins, HLH-2 and HLH-3; despite its cell-type specific role in apoptosis, CES-1 expression is reportedly detected in many embryonic nuclei from the 100-cell stage of embryogenesis through the beginning of morphogenesis, with some CES-1 expression remaining at later embryonic stages; genetic studies indicate that CES-1 is negatively regulated by the bZIP transcription factor CES-2, which can bind CES-1 upstream sequences in vitro and thus may directly regulate CES-1 transcription in vivo
46	puf-4	M4.2	n/a	chrIV 3,207,566	C. elegans PUF-4 protein; contains similarity to Pfam domain PF00806 Pumilio-family RNA binding repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR016024 (Armadillo-type fold)
47	str-37	C50B6.12	n/a	chrV 13,328,296	C. elegans STR-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	F21G4.4	F21G4.4	n/a	chrX 9,898,328	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
49	ZC132.8	ZC132.8	n/a	chrV 4,316,012
50	pqn-11	C09G1.1	n/a	chrX 15,969,125	PQN-11 encodes an unfamiliar protein with a glutamine/asparagine-rich domain that is dispensable for viability and gross morphology.