UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nlp-2	T24D8.5	3e-84	chrX 2,344,350	C. elegans NLP-2 protein ;
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	C10G11.1	C10G11.1	n/a	chrI 6,307,930
4	F13D12.3	F13D12.3	n/a	chrII 11,721,323	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
5	fat-5	W06D12.3	n/a	chrV 17,725,852	fat-5 encodes a delta-9 fatty acid desaturase that is predicted to be mitochondrial; when expressed heterologously in S. cerevisiae, FAT-5 rescues the fatty acid auxotrophy of the yeast delta-9 desaturase mutant ole1.
6	Y42A5A.3	Y42A5A.3	n/a	chrV 11,095,685	contains similarity to Bacillus subtilis Hypothetical protein yhen.; TR:O07596
7	F35H10.2	F35H10.2	n/a	chrIV 8,329,510
8	srw-72	F20E11.6	n/a	chrV 17,467,788	C. elegans SRW-72 protein ;
9	F36A4.2	F36A4.2	n/a	chrIV 4,271,510	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
10	W07A12.4	W07A12.4	n/a	chrII 9,150,253	contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF07707 (BTB And C-terminal Kelch) contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ), IPR011705 (BTB/Kelch-associated), IPR013089 (Kelch related)
11	M176.8	M176.8	n/a	chrII 9,437,409	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
12	far-3	F15B9.1	n/a	chrV 12,997,151	C. elegans FAR-3 protein; contains similarity to Pfam domain PF05823 Nematode fatty acid retinoid binding protein (Gp-FAR-1) contains similarity to Interpro domain IPR008632 (Nematode fatty acid retinoid binding)
13	F42C5.3	F42C5.3	n/a	chrIV 7,286,758	contains similarity to Homo sapiens Intersectin 1 short form transcript variant 8; ENSEMBL:ENSP00000370685
14	F57H12.4	F57H12.4	n/a	chrIV 7,971,993	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR001920 (Asp/Glu racemase), IPR009126 (Cholecystokinin receptor), IPR000276 (GPCR, rhodopsin-like)
15	tag-329	C50F4.3	n/a	chrV 9,535,638	C. elegans TAG-329 protein; contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
16	Y51A2B.1	Y51A2B.1	n/a	chrV 18,373,264	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domains IPR012816 (Conserved hypothetical protein CHP02464), IPR016160 (Aldehyde dehydrogenase, conserved site)
17	C07A12.2	C07A12.2	n/a	chrX 4,545,119
18	F45E1.4	F45E1.4	n/a	chrX 7,986,049
19	srx-20	R13H7.1	n/a	chrIV 6,868,598	C. elegans SRX-20 protein ;
20	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
21	mab-9	T27A1.6	n/a	chrII 518,813	mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail development, specifically affecting the fate of two posterior blast cells in the hindgut, B and F; in the male this results in a grossly abnormal tail lacking spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab-9 may also be part of a network of T-box genes that includes tbx-8, tbx-9 and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab-9 affects movement to some extent though the basis for this defect is unknown; MAB-9 localizes to the nucleus of B and F and their descendents during development.
22	R09E10.2	R09E10.2	n/a	chrIV 10,317,896	contains similarity to Pfam domain PF00102 (Protein-tyrosine phosphatase)
23	sru-23	F36G9.6	n/a	chrV 15,971,479	C. elegans SRU-23 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR003839 (Protein of unknown function DUF215), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
24	F21C10.4	F21C10.4	n/a	chrV 9,127,111	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
25	C08E8.4	C08E8.4	n/a	chrV 18,372,276	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domain IPR012816 (Conserved hypothetical protein CHP02464)
26	T15H9.4	T15H9.4	n/a	chrII 9,612,560	contains similarity to Interpro domains IPR002951 (Atrophin), IPR001478 (PDZ/DHR/GLGF)
27	F14H3.2	F14H3.2	n/a	chrV 16,050,616	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
28	ZK666.8	ZK666.8	n/a	chrII 10,492,235	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
29	F15E6.4	F15E6.4	n/a	chrIV 4,291,666
30	ZC477.2	ZC477.2	n/a	chrIV 7,109,050	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
31	F17E9.3	F17E9.3	n/a	chrIV 8,355,135
32	T02H6.6	T02H6.6	n/a	chrII 683,947
33	R13A5.11	R13A5.11	n/a	chrIII 7,592,386	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
34	F43G9.8	F43G9.8	n/a	chrI 8,618,137	contains similarity to Dugesia japonica DjFGFR1.; TR:Q8MY86
35	ZK688.4	ZK688.4	n/a	chrIII 7,895,076
36	R05A10.1	R05A10.1	n/a	chrIV 14,187,493
37	F21F8.5	F21F8.5	n/a	chrV 8,265,454
38	F59A3.8	F59A3.8	n/a	chrI 5,523,890	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
39	F20A1.10	F20A1.10	n/a	chrV 7,052,940
40	Y37D8A.6	Y37D8A.6	n/a	chrIII 12,857,304	contains similarity to Interpro domains IPR006629 (LPS-induced tumor necrosis factor alpha factor), IPR013032 (EGF-like region, conserved site)
41	W03F11.4	W03F11.4	n/a	chrI 2,238,497	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000694 (Proline-rich region), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
42	F46G11.2	F46G11.2	n/a	chrX 5,789,196
43	flp-5	C03G5.7	n/a	chrX 8,529,581	flp-5 encodes a predicted FMRFamide-like peptide neurotransmitter that increases action potential frequency in the pharyngeal muscle when applied to the pharynx of dissected worms; expressed in the sensory neurons ASE and PVM.
44	F13H8.6	F13H8.6	n/a	chrII 6,285,852
45	clc-1	C09F12.1	n/a	chrX 11,048,302	clc-1 encodes a claudin homolog, closely similar to CLC-2, that is required for normal cohesion of apical junctions in epithelia; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water; CLC-1 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the pharynx to dyes; clc-1 is expressed in spermatheca, pharynx, intestine, hypodermis, the excretory-secretory system, and the cell-cell junctions of the vulva; in pharyngeal cells, CLC-1 colocalizes with AJM-1 in long thin lines, parallel to the pharyngeal axis and lining the lumenal surface, that appear to correspond with apical intercellular junctions.
46	F23D12.3	F23D12.3	n/a	chrX 14,442,916
47	hlh-13	F48D6.3	n/a	chrX 4,250,020	C. elegans HLH-13 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding), IPR002418 (Transcription regulator Myc)
48	numr-1	F08F8.5	n/a	chrIII 7,362,966	C. elegans NUMR-1 protein ;
49	R07E5.6	R07E5.6	n/a	chrIII 4,399,849	contains similarity to Interpro domains IPR005432 (Gamma-aminobutyric-acid A receptor, alpha 2 subunit), IPR009149 (BR22)
50	C25E10.10	C25E10.10	n/a	chrV 9,055,890	C25E10.10 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; C25E10.10 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; C25E10.10 has no obvious function in mass RNAi assays.