UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nlp-23	T24D8.4	1e-64	chrX 2,342,692	nlp-23 encodes three predicted neuropeptide-like proteins; in C. elegans, nlp-23 is part of the FRPamide neuropeptide family that also contains nlp-2 and nlp-22; nlp-23 is expressed in the tail and in dorsal and ventral hypodermis; as loss of nlp-23 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of the nlp-23-encoded peptides in development and/or behavior is not yet known.
2	mom-4	F52F12.3	n/a	chrI 9,898,245	mom-4 encodes a MAP kinase kinase kinase-related protein orthologous to Drosophila Tak1 and the vertebrate MAPKKK7 proteins; during embryonic development, mom-4 activity is required for positive regulation of the Wnt pathway signaling that governs anterior/posterior (A/P) polarity: MOM-4 stimulates the WRM-1/LIT-1-dependent phosphorylation of POP-1, a TCF/LEF-related transcription factor, leading to its downregulation in posterior daughters of A/P cell divisions.
3	nas-21	T11F9.5	n/a	chrV 11,473,207	nas-21 encodes an astacin-like metalloprotease.
4	T09F3.4	T09F3.4	n/a	chrII 10,396,159	T09F3.4 encodes a novel protein.
5	T19D2.3	T19D2.3	n/a	chrX 3,939,726
6	F46C3.2	F46C3.2	n/a	chrX 11,417,473	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
7	R09H3.1	R09H3.1	n/a	chrX 1,660,650	contains similarity to Sulfolobus solfataricus DNA double-strand break repair rad50 ATPase.; SW:Q97WH0
8	srj-8	T28A11.9	n/a	chrV 3,248,476	C. elegans SRJ-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	F49C12.3	F49C12.3	n/a	chrIV 9,301,257	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
10	K07G6.1	K07G6.1	n/a	chrII 1,741,871
11	fbxa-56	T12B5.7	n/a	chrIII 937,668	C. elegans FBXA-56 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
12	ZK402.5	ZK402.5	n/a	chrX 1,399,783	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
13	C50H11.1	C50H11.1	n/a	chrV 3,090,166	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
14	wrn-1	F18C5.2	n/a	chrII 6,557,068	wrn-1 encodes an ortholog of human WRN, which when mutated leads to Werner syndrome (OMIM:277700), and one of four C. elegans homologs of the RecQ DNA helicase family that includes E. coli RecQ; by homology, WRN-1 is predicted to function as a helicase, DNA-dependent ATPase, and exonuclease that plays a key role in DNA replication, recombination, and repair; RNA interference studies in C. elegans and the enhancement of many of the resulting phenotypes by ionizing radiation indicate that wrn-1 affects life span and aging and acts at a DNA damage checkpoint; the wrn-1 phenotypes such as premature aging are similar to those of Werner syndrome; immunolocalization studies indicate that WRN-1 expression is nuclear in cells at the embryonic, larval and adult stages.
15	sra-9	AH6.14	n/a	chrII 9,533,057	C. elegans SRA-9 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
16	fkh-6	B0286.5	n/a	chrII 4,381,579	fkh-6 encodes one of 15 C. elegans forkhead transcription factors; fkh-6 is required for several aspects of male gonadogenesis including asymmetric cell division, cell migration and sex determination and appears to act downstream of tra-1; FKH-6 is specifically expressed in the gonad.
17	F31A9.2	F31A9.2	n/a	chrX 1,795,240
18	srbc-70	F30B5.6	n/a	chrIV 4,227,430	C. elegans SRBC-70 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
19	T07E3.3	T07E3.3	n/a	chrIII 6,904,401	contains similarity to Interpro domain IPR012336 (Thioredoxin-like fold)
20	K09E3.4	K09E3.4	n/a	chrX 17,119,682
21	F02H6.4	F02H6.4	n/a	chrIV 14,217,678	contains similarity to Saccharomyces cerevisiae GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2; SGD:YAL035W
22	F21C10.6	F21C10.6	n/a	chrV 9,124,712	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
23	F07G6.3	F07G6.3	n/a	chrX 1,723,986
24	W05H7.2	W05H7.2	n/a	chrX 1,435,503
25	F45G2.7	F45G2.7	n/a	chrIII 13,433,876	contains similarity to Oceanobacillus iheyensis Two-component response regulator involved in modulation ofsflagellar.; TR:Q8EQW9
26	C08A9.8	C08A9.8	n/a	chrX 17,103,774	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
27	F54C1.1	F54C1.1	n/a	chrI 5,011,081	contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
28	C05C8.8	C05C8.8	n/a	chrV 7,253,723	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
29	F46C5.4	F46C5.4	n/a	chrII 8,837,535
30	str-136	F21F8.9	n/a	chrV 8,278,202	C. elegans STR-136 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
31	F54D10.4	F54D10.4	n/a	chrII 3,806,515
32	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
33	C04G6.7	C04G6.7	n/a	chrII 5,101,080	contains similarity to Interpro domains IPR006081 (Alpha defensin), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR001008 (Mollusc metallothionein, family 2)
34	sdz-34	Y73C8C.7	n/a	chrV 3,108,727	C. elegans SDZ-34 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000533 (Tropomyosin), IPR011016 (Zinc finger, variant RING-type)
35	F53F4.12	F53F4.12	n/a	chrV 13,626,710	contains similarity to Plasmodium falciparum Histidine-rich protein.; SW:HRP3_PLAFS
36	F22E12.3	F22E12.3	n/a	chrV 10,461,278	contains similarity to Petroselinum crispum Reverse transcriptase (Fragment).; TR:Q9ZRL1
37	T09B4.2	T09B4.2	n/a	chrI 6,184,694
38	dos-1	ZK507.4	n/a	chrIII 9,105,304	C. elegans DOS-1 protein ;
39	T11F1.6	T11F1.6	n/a	chrII 2,945,352	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
40	C09D4.2	C09D4.2	n/a	chrI 5,492,333
41	C44B12.6	C44B12.6	n/a	chrIV 1,131,250	contains similarity to Interpro domain IPR010345 (Interleukin-17)
42	F21C10.5	F21C10.5	n/a	chrV 9,125,800	contains similarity to Xenopus tropicalis H/ACA ribonucleoprotein complex subunit 1-like protein.; SW:Q5RJV1
43	Y38H8A.5	Y38H8A.5	n/a	chrIV 13,467,731	The Y38H8A.5 gene encodes a homolog of the human gene ZNF195 (or p57KIP2), which when mutated leads to Beckwith-Wiedemann syndrome (OMIM:130650).
44	tag-143	ZK856.9	n/a	chrV 10,211,282	C. elegans TAG-143 protein; contains similarity to Pfam domain PF04438 HIT zinc finger contains similarity to Interpro domain IPR007529 (Zinc finger, HIT-type)
45	K07D4.2	K07D4.2	n/a	chrII 4,045,127
46	Y43F8C.6	Y43F8C.6	n/a	chrV 19,636,948	contains similarity to Interpro domains IPR001412 (Aminoacyl-tRNA synthetase, class I, conserved site), IPR009057 (Homeodomain-like)
47	tat-6	F02C9.3	n/a	chrV 3,131,186	C. elegans TAT-6 protein; contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006069 (ATPase, P-type cation exchange, alpha subunit), IPR006539 (Phospholipid-translocating P-type ATPase, flippase), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
48	srx-121	C04E12.8	n/a	chrV 3,371,855	C. elegans SRX-121 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
49	sqv-8	ZK1307.5	n/a	chrII 9,648,550	The sqv-8 gene encodes a glucuronyl transferase, biochemically active in vitro, that is required for cytokinesis of one-cell embryos and for vulval morphogenesis; SQV-8 is homologous to three distinct glucuronyl transferases (GlcAT-I, GlcAT-P and GlcAT-D) that play a role in the synthesis of different glycoconjugates; the common requirement for SQV-8 in both cytokinesis and morphogenesis may be to promote filling an extracellular space with hygroscopic proteoglycans (either in the eggshell, or underneath the L4 cuticle), which in turn may cause the space to fill with fluid.
50	srj-7	T28A11.10	n/a	chrV 3,245,861	C. elegans SRJ-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)