UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ram-5	T24C2.1	0	chrX 14,553,138	ram-5 encodes a novel transmembrane protein; during male tail development, ram-5 activity is required in ray structural cells for proper sensory ray morphogenesis; a RAM-5::GFP fusion protein is expressed in all of the ray structural cells of the male tail, as well as additional sensory support cells in both hermaphrodites and males, including those of the inner labial sensilla as well as the ADE, PDE, and phasmid socket cells.
2	R04B3.2	R04B3.2	n/a	chrX 2,472,601	The R04B3.2 gene encodes an ortholog of the human gene LYSOSOMAL GLYCOSYLASPARAGINASE (AGA; OMIM:208400), which when mutated leads to aspartylglucosaminuria (OMIM:208400).
3	srx-118	T21B4.12	n/a	chrII 12,526,763	C. elegans SRX-118 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
4	T25G3.4	T25G3.4	n/a	chrI 7,566,145	T25G3.4 encodes a putative mitochondrial glycerol-3-phosphate dehydrogenase, paralogous to Y50E8A.6 and orthologous to human GPD2 (OMIM:138430, mutated in type II diabetes mellitus); T25G3.4 transcripts are not obviously enriched during oogenesis, but T25G3.4 is predicted to be coexpressed in an operon with chs-1 and T25G3.3; such coexpression, if real, may simply reflect all three genes being required for oogenesis, rather than some more detailed functional connection; T25G3.4 has no obvious function in mass RNAi assays.
5	sri-11	T22H2.3	n/a	chrI 11,696,802	C. elegans SRI-11 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region)
6	R03H4.1	R03H4.1	n/a	chrV 9,018,100	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
7	rps-8	F42C5.8	n/a	chrIV 7,313,435	rps-8 encodes a small ribosomal subunit S8 protein; by homology, RPS-8 is predicted to function in protein biosynthesis; in C. elegans, RPS-8 activity is required for germline development and the overall health of the animal.
8	F53C3.8	F53C3.8	n/a	chrII 3,891,751
9	elp-1	F38A6.2	n/a	chrV 20,762,946	elp-1 encodes a WD repeat-containing protein that is the sole C. elegans EMAP (echinoderm microtubule-associated protein) homolog; ELP-1 binds microtubules in vitro, but as loss of ELP-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ELP-1 in C. elegans development and/or behavior is not yet known; ELP-1 is expressed in many tissues, including body wall muscle, male-specific sex muscles, the vulva, spermatheca, sensory neurons, and intestinal cells.
10	C07G1.7	C07G1.7	n/a	chrIV 8,211,372
11	F09C11.1	F09C11.1	n/a	chrIV 543,658
12	F59A2.2	F59A2.2	n/a	chrIII 3,408,380	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EN31
13	str-149	Y32B12B.5	n/a	chrV 16,574,182	C. elegans STR-149 protein ;
14	sph-1	F42G8.11	n/a	chrIV 8,132,914	sph-1 encodes a member of the synaptophysin/synaptoporin family that contains a MARVEL domain, a membrane-associating domain found in lipid-associating proteins, and contains a transmembrane domain.
15	K06G5.3	K06G5.3	n/a	chrX 14,221,334	contains similarity to Saccharomyces cerevisiae Required for invasion and pseudohyphae formation in response to nitrogen starvation; SGD:YIR019C
16	srsx-24	C03G6.16	n/a	chrV 7,378,672	C. elegans SRSX-24 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
17	srw-103	ZK697.5	n/a	chrV 1,718,354	C. elegans SRW-103 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
18	Y49F6C.2	Y49F6C.2	n/a	chrII 3,379,231
19	nhr-181	F38H12.3	n/a	chrV 4,097,665	nhr-181 encodes a putative nuclear hormone receptor (NHR), belonging to a large nematode-specific expanded family of NHRs, that inhibits CEP-1- and HUS-1-dependent germline apoptosis as do BMK-1, RAD-50, and RAD-51.
20	srh-250	C49D10.3	n/a	chrII 3,879,253	C. elegans SRH-250 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	C24A3.4	C24A3.4	n/a	chrX 8,993,472	contains similarity to Pfam domain PF02515 CoA-transferase family III contains similarity to Interpro domains IPR016160 (Aldehyde dehydrogenase, conserved site), IPR003673 (CoA-transferase family III)
22	F38C2.1	F38C2.1	n/a	chrIV 16,249,570	contains similarity to Carnobacterium piscicola ATP-dependent translocator.; TR:Q46317
23	R05D7.5	R05D7.5	n/a	chrI 12,186,205	contains similarity to Ascaris suum P40.; TR:Q7YXJ9
24	R07B1.8	R07B1.8	n/a	chrX 9,871,676
25	nhr-280	C29F9.13	n/a	chrIII 130,464	C. elegans NHR-280 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
26	F43C1.5	F43C1.5	n/a	chrIII 4,229,767	contains similarity to Pfam domain PF02845 CUE domain contains similarity to Interpro domains IPR003892 (Ubiquitin system component Cue), IPR009060 (UBA-like)
27	srh-112	T19C9.2	n/a	chrV 17,225,620	C. elegans SRH-112 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	osm-7	T05D4.4	n/a	chrIII 13,578,274	C. elegans OSM-7 protein ;
29	sri-57	F22E5.16	n/a	chrII 2,671,336	C. elegans SRI-57 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
30	flr-1	F02D10.5	n/a	chrX 13,454,529	flr-1 encodes an ion channel that belongs to the DEG/ENaC sodium channel superfamily; flr-1 activity is essential for normal defecation rhythm, growth rates, expulsion, and dauer larvae formation; a rescuing FLR-1::GFP reporter is expressed in the intestine from embryonic to adult stages where it localizes to the membranes facing the inner lumen as well as to part of the lateral membrane between intestinal cells.
31	F52G3.5	F52G3.5	n/a	chrX 16,974,629	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR006150 (Cysteine-rich repeat), IPR003582 (Metridin-like ShK toxin)
32	ZK563.2	ZK563.2	n/a	chrX 3,371,077	contains similarity to Pfam domain PF02690 Na+/Pi-cotransporter contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR003841 (Na+/Pi-cotransporter)
33	C03F11.2	C03F11.2	n/a	chrX 5,395,712	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
34	C34E11.2	C34E11.2	n/a	chrX 11,808,336	contains similarity to Pfam domain PF03166 MH2 domain contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR000694 (Proline-rich region), IPR001132 (SMAD domain, Dwarfin-type), IPR017855 (SMAD domain-like)
35	fbxa-166	C08E3.9	n/a	chrII 1,617,962	C. elegans FBXA-166 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
36	ZC513.2	ZC513.2	n/a	chrV 8,055,592	contains similarity to Pfam domain PF01273 LBP / BPI / CETP family, N-terminal domain contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
37	dmd-3	Y43F8C.10	n/a	chrV 19,652,807	C. elegans DMD-3 protein; contains similarity to Pfam domain PF00751 DM DNA binding domain contains similarity to Interpro domain IPR001275 (DM DNA-binding)
38	Y57G11A.3	Y57G11A.3	n/a	chrIV 14,502,754	contains similarity to Pfam domain PF00412 LIM domain contains similarity to Interpro domain IPR001781 (Zinc finger, LIM-type)
39	F16H6.5	F16H6.5	n/a	chrV 18,202,582	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
40	Y38H6A.3	Y38H6A.3	n/a	chrV 20,342,053	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
41	srx-104	F40H7.7	n/a	chrII 3,699,139	C. elegans SRX-104 protein ;
42	M153.3	M153.3	n/a	chrX 12,143,295	contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
43	T07F10.6	T07F10.6	n/a	chrV 12,865,830	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
44	rnp-1	ZK863.7	n/a	chrV 12,193,297	C. elegans RNP-1 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1), IPR001878 (Zinc finger, CCHC-type)
45	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
46	C47D12.8	C47D12.8	n/a	chrII 11,700,677	C47D12.8 encodes an ortholog of the DNA repair protein XPF/ERCC4, which when mutated in humans leads to xeroderma pigmentosum (complementation group F; OMIM:133520); C47D12.8(RNAi) animals are hypersensitive to ultraviolet radiation, with increased germ cell apoptosis and embryonic lethality; C47D12.8 protein interacts with F10G8.7 (an ERCC1 ortholog) in yeast two-hybrid assays; C47D12.8 is expressed broadly in both embryonic and postembryonic animals, and is required for embryonic development; C47D12.8 is upregulated in dauers, and shares an operon with kel-1 and VF13D12L.3.
47	fbxa-130	F42A6.8	n/a	chrIV 3,340,450	C. elegans FBXA-130 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
48	col-162	Y2H9A.3	n/a	chrV 13,442,665	C. elegans COL-162 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
49	srh-18	C50B6.5	n/a	chrV 13,319,254	C. elegans SRH-18 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	F55C5.1	F55C5.1	n/a	chrV 12,263,644	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)