UCSC C. elegans Gene Sorter

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

UCSC C. elegans Gene Sorter

genome assembly search

sort by display output

#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T23C6.4	T23C6.4	1e-155	chrX 17,148,667	contains similarity to Lactobacillus plantarum Translation initiation factor IF-2.; SW:Q88VK7
2	C07A9.9	C07A9.9	n/a	chrIII 9,665,312	contains similarity to Guillardia theta RNA polymerase sigma factor.; TR:Q8S9D0
3	ifta-2	T28F3.6	n/a	chrIV 17,301,376	ifta-2 encodes a ciliary protein, orthologous to human RABL5, that is required for normally short life span and dauer formation; IFTA-2 is expressed in amphid, labial, and phasmid ciliated sensory neurons; intracellularly, IFTA-2 resides in the bases and axonemes of cilia, colocalizing with DAF-2 and AGE-1; IFTA-2 may be either a cargo or a cargo-docking component of intraflagellar transport (IFT) by the IFT-B complex; ciliary basal localization of IFTA-2 is abolished by a T42N mutation predicted to lock ITFA-2 into an inactive, GDP-bound conformation; ifta-2(tm1724) mutants have abnormally long lifespans and constitutive dauer formation, perhaps because IFTA-2 regulates DAF-2 signalling from ciliated sensory neurons; IFTA-2 is not required for cilium assembly or IFT, nor is it required for chemosensation or osmosensation; the ciliary localization of IFTA-2 is conserved in RABL5; via an X-box in its promoter, ifta-2 is a candidate for direct regulation by DAF-19.
4	clc-2	C01C10.1	n/a	chrX 7,432,451	clc-2 encodes a claudin homolog, closely similar to CLC-1, that is required for normal cohesion of apical junctions in epithelia; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water; CLC-2 maintains the impermeability ('barrier function') of epithelia, since clc-1(RNAi) animals have abnormal permeability of the hypodermis to dyes; clc-2 is expressed in hypodermal seam cells, with two diffuse lines of CLC-2 protein.
5	lim-4	ZC64.4	n/a	chrX 3,871,505	lim-4 encodes a LIM homeodomain protein homologous to murine Lhx6 and L3/Lhx7, and to Drosophila ARROWHEAD; LIM-4 is required for differentiation of AWB chemosensory neurons, for several but not all aspects of RID motor neuron differentiation, expression of ser-2, repulsion from chemosensory repellants, SAA neurite outgrowth, and normal locomotion and head foraging; lim-4 is expressed in AWB, RID, RIV, RMDL, RMDR, RMEV, four SAA neurons, and four SIA neurons.
6	srsx-14	C39H7.5	n/a	chrIV 5,625,990	C. elegans SRSX-14 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
7	F55D10.4	F55D10.4	n/a	chrX 4,718,585
8	M03C11.1	M03C11.1	n/a	chrIII 10,394,622	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
9	arl-3	F19H8.3	n/a	chrII 14,607,534	arl-3 encodes a member of the ARL (ADP-ribosylation factor(ARF)-like) family of proteins which are very similar to ARF proteins but lack the ability to stimulate ADP ribosylation by cholera toxin; as loss of arl-3 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ARL-3 is not yet known.
10	nhr-67	C08F8.8	n/a	chrIV 11,172,266	nhr-67 encodes a nuclear receptor that is orthologous to Drosophila and vertebrate tailless hormone receptors; during development, nhr-67 plays an essential role in larval development and also functions as part of a complex regulatory network that regulates vulval patterning and differentiation and thus, egg laying; specifically, nhr-67 functions to positively regulate gene expression in the vulA, vulD, and vulF cells and negatively regulate gene expression in vulE and vulF; in regulating vulval gene expression, nhr-67 functions together with other transcription factors, including egl-38, lin-11, and cog-1; nhr-67 reporter fusion constructs are expressed dynamically in multiple vulval cell types as well as in head neurons, the hyp7 syncytium, late-stage embryos, the male tail, the anchor cell, and the linker cell.
11	T26E4.3	T26E4.3	n/a	chrV 15,783,606	contains similarity to Pfam domain PF01531 (Glycosyl transferase family 11)
12	pdl-1	C27H5.1	n/a	chrII 7,184,432	C. elegans PDL-1 protein; contains similarity to Pfam domain PF05351 GMP-PDE, delta subunit contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR017287 (Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit), IPR008015 (GMP phosphodiesterase, delta subunit)
13	ctbp-1	F49E10.5	n/a	chrX 5,867,998	tag-45 encodes a D-isomer specific 2-hydroxyacid dehydrogenase.
14	F57A8.1	F57A8.1	n/a	chrV 10,045,776	contains similarity to Interpro domain IPR009058 ()
15	sol-1	C15A11.3	n/a	chrI 7,392,485	C. elegans SOL-1 protein; contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
16	sox-3	F40E10.2	n/a	chrX 14,692,543	C. elegans SOX-3 protein; contains similarity to Pfam domain PF00505 HMG (high mobility group) box contains similarity to Interpro domains IPR000910 (High mobility group box, HMG1/HMG2), IPR009071 (High mobility group box, HMG), IPR000135 (High mobility group box, HMG1/HMG2, subgroup)
17	flp-17	C52D10.11	n/a	chrIV 17,191,022	C. elegans FLP-17 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
18	F09C6.3	F09C6.3	n/a	chrV 16,879,465	contains similarity to Saccharomyces cerevisiae DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; SGD:YMR173W
19	sdz-3	C29F5.2	n/a	chrII 6,300,414	C. elegans SDZ-3 protein ;
20	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
21	F32H2.6	F32H2.6	n/a	chrI 8,999,077	contains similarity to Pfam domain PF00109 Beta-ketoacyl synthase, N-terminal domain contains similarity to Interpro domains IPR016038 (Thiolase-like, subgroup), IPR000794 (Beta-ketoacyl synthase), IPR014030 (Beta-ketoacyl synthase, N-terminal), IPR016039 (Thiolase-like)
22	dyf-5	M04C9.5	n/a	chrI 9,360,991	dyf-5 encodes a putative MAP kinase orthologous to human MAK/ICK (OMIM:154235), Chlamydomonas reinhardtii LF4, and Leishmania mexicana MPK9; DYF-5 negatively regulates cilial length, restricts KAP-1 to middle ciliary segments, is required for normal localization of six IFT components, and is required for OSM-3 to comigrate normally with IFT particles; DYF-5 is also required for dye-filling of amphid and phasmid neurons and for normal chemotaxis, dauer formation, and male mating; DYF-5 is expressed in head neurons (including amphid neurons), tail neurons (including phasmid neurons), CAN cells, excretory canal neurons, posterior lateral ganglion neurons and in many male tail cells; dyf-5 mutant cilia are abnormally elongated, either failing to enter the amphid channel or accumulating IFT proteins at their distal ends, whereas DYF-5 overexpression results in truncated cilia; the dyf-5 promoter region contains an X-box, predicted to be bound and transcriptionally activated by DAF-19, and dyf-5 is regulated by DAF-19 in vivo; dyf-5 animals are slightly shorter than normal.
23	F46F5.4	F46F5.4	n/a	chrII 805,580	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
24	C12D5.9	C12D5.9	n/a	chrV 7,689,147	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
25	mif-3	F13G3.9	n/a	chrI 7,313,193	C. elegans MIF-3 protein; contains similarity to Pfam domain PF01187 Macrophage migration inhibitory factor (MIF) contains similarity to Interpro domains IPR014347 (Tautomerase), IPR001398 (Macrophage migration inhibitory factor)
26	sup-9	F34D6.3	n/a	chrII 2,685,863	sup-9 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; sup-9 was originally defined by gain-of-function mutations that result in defects in pharyngeal, body-wall, egg-laying, and enteric muscle activation; loss of sup-9 function via reversion or RNA-mediated interference (RNAi) does not result in any abnormalities suggesting that SUP-9 may function redundantly with other TWK channels; SUP-9 is expressed in neurons and muscle.
27	Y113G7B.11	Y113G7B.11	n/a	chrV 20,209,977	contains similarity to Naja atra Cardiotoxin 10 precursor.; TR:Q9W6W6
28	Y42A5A.4	Y42A5A.4	n/a	chrV 11,106,364	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
29	F07C3.2	F07C3.2	n/a	chrV 9,226,731
30	set-19	W01C8.3	n/a	chrX 5,677,695	set-19 encodes a SET domain-containing protein; SET-19 has no non-nematode orthologs, but several paralogs (SET-6, SET-13, SET-15, SET-20, SET-21, and SET-32); neither set-19(ok1813) nor set-19(RNAi) have any obvious phenotypes.
31	unc-24	F57H12.2	n/a	chrIV 7,980,963	unc-24 encodes a protein that contains a stomatin-like domain and a lipid transfer domain; unc-24 activity is essential for normal locomotion and for wild-type sensitivity to lipid-soluble volatile anesthetics; unc-24 is genetically epistatic to unc-79 and to unc-1, which encodes an additional stomatin whose stability and localization to the nerve ring are dependent upon UNC-24; unc-24 is expressed in the touch receptor neurons as well as neurons in the ventral cord.
32	tkr-1	C38C10.1	n/a	chrIII 9,386,535	tkr-1 encodes a G protein-coupled receptor that is the C. elegans tachykinin-like neuropeptide receptor homolog; by homology, TKR-1 is predicted to function in modulation of excitatory neurotransmission; as loss of tkr-1 activity via RNAi results in moderate reduction of fat content, TKR-1 may play a specific role in regulating lipid metabolism; a tkr-1 reporter gene fusion is reportedly expressed in the socket cells of the deirid and post-deirid sensilla from the L2 larval stage through adulthood.
33	F35F10.12	F35F10.12	n/a	chrV 3,314,352	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000694 (Proline-rich region), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
34	nhr-7	F54D1.4	n/a	chrIV 11,267,544	C. elegans NHR-7 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000694 (Proline-rich region), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
35	R01E6.7	R01E6.7	n/a	chrX 13,568,618	contains similarity to Ectocarpus siliculosus virus EsV-1-142.; TR:Q8QKY0
36	F33E2.6	F33E2.6	n/a	chrI 12,589,287	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
37	T25B6.4	T25B6.4	n/a	chrX 9,016,157
38	rab-14	K09A9.2	n/a	chrX 15,605,871	rab-14 encodes a member of the Rab GTPase family.
39	Y43F8B.10	Y43F8B.10	n/a	chrV 19,475,668
40	sng-1	T08A9.3	n/a	chrX 7,328,590	sng-1 encodes the C. elegans synaptogyrin ortholog, a vertebrate integral membrane synaptic vesicle protein; loss-of-function mutations in sng-1 result in no obvious defects in synaptogenesis or neuronal activity, suggesting that SNG-1 is likely required for more subtle neuronal functions; SNG-1::GFP reporters are expressed throughout the nervous system in neurons in the dorsal and ventral nerve cords, as well as the anterior nerve ring; SNG-1 colocalizes with the synaptic vesicle component SNT-1.
41	sdz-23	F58G4.4	n/a	chrV 8,100,032	sdz-23 encodes a putatively secreted protein with a single EGF domain, with some similarity to LAG-2; sdz-23 begins to be expressed in the E blastomere of 8-cell embryos, and continues to be expressed solely in the E lineage througout embryogenesis; sdz-23 requires SKN-1 and WRM-1 for E lineage expression, and is a putative MED-1/2 target gene; sdz-23 is both activated by POP-1 (with SYS-1 as coactivator, in the E lineage) and repressed by POP-1 (in the MS lineage), while the dependence of sdz-23 on WRM-1 for E lineage expression is alleviated by loss of POP-1, indicating that WRM-1 switches POP-1 from repression to activation in the E lineage; sdz-23 requires SYS-1 for normal embryonic expression; SDZ-23 has no obvious function in mass RNAi assays.
42	ZC239.3	ZC239.3	n/a	chrII 3,216,335	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
43	R06C1.6	R06C1.6	n/a	chrI 11,950,040	contains similarity to Saccharomyces cerevisiae CCR4 Associated Factor 120 kDa; SGD:YNL278W
44	mlt-8	W08F4.6	n/a	chrII 570,690	mlt-8 encodes a novel protein; during development, mlt-8 activity is required for molting; a mlt-8::gfp reporter is expressed in hypodermal cells and in a single posterior neuron.
45	M28.4	M28.4	n/a	chrII 10,645,246	contains similarity to Homo sapiens Kinesin-like protein 2; ENSEMBL:ENSP00000324020
46	F53A9.4	F53A9.4	n/a	chrX 8,705,694
47	ttr-28	R90.3	n/a	chrV 12,904,670	C. elegans TTR-28 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
48	R02F2.2	R02F2.2	n/a	chrIII 5,493,250	contains similarity to Pfam domain PF00621 RhoGEF domain contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR011046 (WD40 repeat-like), IPR001331 (Guanine-nucleotide dissociation stimulator, CDC24, conserved site)
49	srbc-10	C18B10.2	n/a	chrV 7,492,430	C. elegans SRBC-10 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
50	C31H1.2	C31H1.2	n/a	chrIV 5,792,361	contains similarity to Pfam domain PF02013 Cellulose or protein binding domain contains similarity to Interpro domains IPR003616 (Post-SET zinc-binding region), IPR000215 (Protease inhibitor I4, serpin), IPR002883 (Dockerin, cellulose-binding family V)