UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	dpy-20	T22B3.1	0	chrIV 11,698,305	dpy-20 encodes a BED zinc finger protein, with no known homologs outside of nematodes, that is required for normal body morphology.
2	T11G6.4	T11G6.4	n/a	chrIV 10,850,812	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR008075 (Lipocalin-1 receptor), IPR016196 (MFS general substrate transporter)
3	R05A10.6	R05A10.6	n/a	chrIV 14,167,109	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
4	gst-42	D1053.1	n/a	chrX 11,727,007	gst-42 is orthologous to the human gene GLUTATHIONE TRANSFERASE ZETA-1 (also known as MALEYLACETOACETATE ISOMERASE; GSTZ1; OMIM:603758), which when mutated is thought to lead to a variety of type I tyrosinemia.
5	C27C7.2	C27C7.2	n/a	chrI 11,433,261	contains similarity to Pfam domain PF01697 (Domain of unknown function)
6	ZC190.2	ZC190.2	n/a	chrV 8,682,033	contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
7	T16G1.2	T16G1.2	n/a	chrV 12,931,137	contains similarity to Interpro domain IPR000694 (Proline-rich region)
8	T22D1.4	T22D1.4	n/a	chrIV 6,911,758	contains similarity to Pfam domain PF04597 Ribophorin I contains similarity to Interpro domain IPR007676 (Ribophorin I)
9	F46C5.9	F46C5.9	n/a	chrII 8,809,612	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
10	ptr-14	R09H10.4	n/a	chrIV 10,618,200	ptr-14 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-14 is weakly required for normal molting from L4 to adult stages; PTR-14 is also required for normal growth to full size and locomotion.
11	fbxa-64	T28A11.21	n/a	chrV 3,277,607	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
12	ptr-15	T07H8.6	n/a	chrV 6,968,181	ptr-15 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-15 has no known function in vivo.
13	pcp-1	ZK112.1	n/a	chrIII 7,759,923	C. elegans PCP-1 protein; contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domain IPR008758 (Peptidase S28)
14	ifp-1	C43C3.1	n/a	chrX 9,677,940	ifp-1 encodes a nonessential intermediate filament protein; IFP-1 is predicted to function as a structural component of the cytoskeleton; IFP-1 has no obvious function in RNAi assays.
15	F52F10.2	F52F10.2	n/a	chrV 1,549,423	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
16	C33D3.3	C33D3.3	n/a	chrX 10,485,911	contains similarity to Interpro domains IPR000679 (Zinc finger, GATA-type), IPR013088 (Zinc finger, NHR/GATA-type), IPR011011 (Zinc finger, FYVE/PHD-type)
17	cyp-35A2	C03G6.15	n/a	chrV 7,363,242	C. elegans CYP-35A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
18	tag-197	F08C6.3	n/a	chrX 7,566,676	C. elegans TAG-197 protein; contains similarity to Pfam domain PF04129 Vps52 / Sac2 family contains similarity to Interpro domain IPR007258 (Vps52/Sac2)
19	fut-8	C10F3.6	n/a	chrV 5,988,610	fut-8 encodes a core alpha 1,6-fucosyltransferase; characterization of a recombinant form of the protein that contains the catalytic region of FUT-8 reveals a sustrate requirement for unsubstituted nonreducing terminal GlcNAc residues.
20	hog-1	W06B11.4	n/a	chrX 5,852,661	hog-1 encodes a hedgehog-like protein, with a solitary Hint/Hog domain; the function of HOG-1's isolated Hint/Hog domain is unknown; in proteins where they coexist with other, N-terminal, domains, the Hint/Hog domain is predicted to cut its host protein into two halves and then covalently link cholesterol to the C-terminus of the N-terminal domain; HOG-1 is weakly required for normal molting; HOG-1 is also required for normal adult alae formation, growth to full size, cuticle adhesion, and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
21	F55E10.6	F55E10.6	n/a	chrX 8,345,470	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
22	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
23	nuo-1	C09H10.3	n/a	chrII 11,099,005	nuo-1 encodes a encodes a 51 kDa subunit of mitochondrial complex I that is required for oxidative phosphorylation, resistance to volatile anesthetics, and progression through development; nuo-1 is orthologous to human NDUFV1 (OMIM:161015, mutated in Leigh syndrome); nuo-1(ua1) induces a developmental arrest at the third larval (L3) stage that blocks reproduction, and thus is lethal to a population homozygous for nuo-1(ua1); yet arrested L3 nuo-1(ua1) animals have an individual lifespan significantly longer than normal.
24	H23N18.4	H23N18.4	n/a	chrV 4,902,178	contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
25	T20D4.3	T20D4.3	n/a	chrV 3,420,496	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
26	K11G9.2	K11G9.2	n/a	chrV 6,675,280	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
27	pcp-2	F23B2.12	n/a	chrIV 9,162,862	C. elegans PCP-2 protein; contains similarity to Pfam domain PF05577 Serine carboxypeptidase S28 contains similarity to Interpro domains IPR008758 (Peptidase S28), IPR000258 (Bacterial ice-nucleation proteins octamer repeat)
28	pgp-13	F22E10.2	n/a	chrX 12,741,422	pgp-13 encodes a member of the ABC transporter family with high similarity to the vertebrate MDR (multidrug resistance) family; PGP-13 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-13 activity via large-scale RNAi screens does not result in any obvious defects, the precise role of pgp-13 in C. elegans development and/or behavior is not yet known; pgp-13 promoter-gfp fusion proteins are expressed in larvae and adults in the posterior intestine and the amphids.
29	R186.6	R186.6	n/a	chrV 12,958,187	contains similarity to Pfam domain PF00581 Rhodanese-like domain contains similarity to Interpro domain IPR001763 (Rhodanese-like)
30	H25K10.1	H25K10.1	n/a	chrIV 16,204,661	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR015914 (Purple acid phosphatase, N-terminal), IPR004843 (Metallophosphoesterase)
31	che-14	F56H1.1	n/a	chrI 5,750,511	che-14 encodes a protein with a sterol-sensing domain; CHE-14 protein is involved in the exocytotic secretion of lipid-modified proteins at the apical surface of certain epithelial cells.
32	Y43F8C.4	Y43F8C.4	n/a	chrV 19,627,836	contains similarity to Homo sapiens 90 kDa protein; VG:OTTHUMP00000182483
33	his-3	T10C6.12	n/a	chrV 16,040,965	his-3 encodes an H2A histone; by homology, HIS-3 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-3 is a replication-dependent histone locus that resides in the HIS1 cluster on chromosome V.
34	snx-1	C05D9.1	n/a	chrX 1,130,709	C. elegans SNX-1 protein; contains similarity to Pfam domains PF09325 (Vps5 C terminal like) , PF00787 (PX domain) contains similarity to Interpro domains IPR001683 (Phox-like), IPR013822 (Signal recognition particle, SRP54 subunit, helical bundle), IPR015404 (Vps5 C terminal like)
35	vrs-1	ZC513.4	n/a	chrV 8,033,348	vrs-1 encodes a predicted valyl-tRNA synthetase that affects embryonic viability, growth, and morphology
36	F30H5.3	F30H5.3	n/a	chrIII 508,704	contains similarity to Pfam domains PF01683 (EB module) (3), PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) (5)contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR008197 (Whey acidic protein, 4-disulphide core), IPR006150 (Cysteine-rich repeat), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR006149 (Nematode-specific EB region)
37	Y56A3A.19	Y56A3A.19	n/a	chrIII 11,915,313	contains similarity to Pfam domain PF00550 Phosphopantetheine attachment site contains similarity to Interpro domains IPR006163 (Phosphopantetheine-binding), IPR009081 (Acyl carrier protein-like), IPR003231 (Acyl carrier protein (ACP))
38	nhr-210	R11G11.12	n/a	chrV 518,366	C. elegans NHR-210 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
39	pqn-29	F10F2.9	n/a	chrIII 4,645,137	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
40	F08A8.3	F08A8.3	n/a	chrI 12,948,957	contains similarity to Pfam domains PF01756 (Acyl-CoA oxidase) , PF02770 (Acyl-CoA dehydrogenase, middle domain) contains similarity to Interpro domains IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR012258 (Acyl-CoA oxidase), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR002655 (Acyl-CoA oxidase, C-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal)
41	H43E16.1	H43E16.1	n/a	chrII 6,676,762	contains similarity to Interpro domain IPR000082 (SEA)
42	Y45G12C.1	Y45G12C.1	n/a	chrV 2,567,280	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
43	W02D3.2	W02D3.2	n/a	chrI 6,738,931	contains similarity to Pfam domain PF01180 Dihydroorotate dehydrogenase contains similarity to Interpro domains IPR001295 (Dihydroorotate dehydrogenase, core), IPR013785 (Aldolase-type TIM barrel), IPR005719 (Dihydroorotate dehydrogenase, class 2), IPR012135 (Dihydroorotate dehydrogenase, classes 1 and 2)
44	F23H12.5	F23H12.5	n/a	chrV 12,361,146	contains similarity to Interpro domains IPR008085 (Thrombospondin, subtype 1), IPR000884 (Thrombospondin, type I)
45	pas-2	D1054.2	n/a	chrV 10,770,774	pas-2 encodes a proteasome subunit with highest similarity to vertebrate proteasome alpha 2 subunits.
46	R07B1.7	R07B1.7	n/a	chrX 9,869,453	contains similarity to Candida albicans Chitinase 2 precursor (EC 3.2.1.14).; SW:CHI2_CANAL
47	tag-257	F46G11.3	n/a	chrX 5,784,865	C. elegans TAG-257 protein; contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
48	B0303.15	B0303.15	n/a	chrIII 8,717,978	contains similarity to Pfam domains PF00298 (Ribosomal protein L11, RNA binding domain) , PF03946 (Ribosomal protein L11, N-terminal domain) contains similarity to Interpro domain IPR000911 (Ribosomal protein L11)
49	F07H5.8	F07H5.8	n/a	chrII 8,802,913	contains similarity to Pfam domains PF06493 (Protein of unknown function (DUF1096)) , PF02363 (Cysteine rich repeat) (21)contains similarity to Interpro domains IPR003341 (Cysteine rich repeat, tripleX), IPR009475 (Protein of unknown function DUF1096), IPR013032 (EGF-like region, conserved site)
50	col-17	F11G11.10	n/a	chrII 4,866,996	col-17 encodes a collagen which is expressed in all developmental stages except eggs, like col-15, col-16, and col-20; collagen genes with this expression pattern may be used for synthesis of cuticles after the L1 stage (e.g., the L4 cuticle).