UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T21B10.3	T21B10.3	0	chrII 8,936,627	contains similarity to Homo sapiens Conserved hypothetical protein; VG:OTTHUMP00000076919
2	M01H9.2	M01H9.2	n/a	chrIV 4,461,106	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domains IPR002350 (Proteinase inhibitor I1, Kazal), IPR001368 (TNFR/CD27/30/40/95 cysteine-rich region), IPR003582 (Metridin-like ShK toxin)
3	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
4	ZK1053.3	ZK1053.3	n/a	chrI 13,248,255	contains similarity to Interpro domain IPR011008 (Dimeric alpha-beta barrel)
5	F56F11.5	F56F11.5	n/a	chrIII 2,853,197
6	C15H9.2	C15H9.2	n/a	chrX 6,119,566	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
7	F58D12.3	F58D12.3	n/a	chrV 14,062,015	contains similarity to Interpro domain IPR009091 (Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)
8	T24H10.4	T24H10.4	n/a	chrII 9,110,325	contains similarity to Pfam domain PF05705 Eukaryotic protein of unknown function (DUF829) contains similarity to Interpro domain IPR008547 (Protein of unknown function DUF829, eukaryotic)
9	C36B7.3	C36B7.3	n/a	chrX 7,101,897
10	col-52	D1007.2	n/a	chrI 4,572,052	C. elegans COL-52 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
11	T26C11.4	T26C11.4	n/a	chrX 1,843,047	contains similarity to Dictyostelium discoideum Similar to Homo sapiens (Human). Dentin sialophosphoprotein [Contains:sDentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentinssialoprotein (DSP)].; TR:Q869X8
12	str-131	C09H5.6	n/a	chrV 8,081,002	C. elegans STR-131 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	osm-1	T27B1.1	n/a	chrX 16,546,188	osm-1 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex B component IFT172; OSM-1 is a presumptive cargo molecule for kinesin-II, and OSM-1 is required, along with OSM-6, for the proper assembly of the middle segments of sensory cilia; osm-1 may act in a pathway with avr-14 to affect resistance to ivermectin-induced cessation of pumping, and mutants are defective in avoidance of solutions of high osmotic strength; an OSM-1::GFP fusion protein is expressed in amphid and phasmid chemosensory neurons where it undergoes both anterograde and retrograde intraflagellar transport.
14	cyld-1	F40F12.5	n/a	chrIII 9,904,526	F40F12.5 encodes an ortholog of human CYLD1 (OMIM:605018, mutated in cylindromatosis); CYLD1 binds several members of the NF-kappaB signalling pathway, and can deubiquitinate target proteins.
15	T24C2.3	T24C2.3	n/a	chrX 14,544,021	contains similarity to Arabidopsis thaliana F25I16.10 protein.; TR:Q9FZ78
16	srsx-17	F58D7.1	n/a	chrV 5,929,015	C. elegans SRSX-17 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
17	F54G2.2	F54G2.2	n/a	chrX 2,636,226	contains similarity to Pfam domain PF00098 Zinc knuckle contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001878 (Zinc finger, CCHC-type)
18	sir-2.3	F46G10.3	n/a	chrX 13,332,774	C. elegans SIR-2.3 protein; contains similarity to Pfam domain PF02146 Sir2 family contains similarity to Interpro domain IPR003000 (NAD-dependent histone deacetylase, silent information regulator Sir2)
19	gcy-36	C46E1.2	n/a	chrX 15,482,280	gcy-36 encodes a predicted soluble guanylate cyclase that genetically interacts with npr-1 with respect to feeding behavior; expressed in AQR, PQR, and URX3.
20	gcy-2	R134.2	n/a	chrII 9,509,771	gcy-2 encodes a predicted transmembrane guanylyl cyclase; as loss of gcy-2 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-2 in C. elegans development and/or behavior is not yet known; by sequence similarity, however, GCY-2 can be predicted to function in chemosensory signal transduction.
21	H25P06.4	H25P06.4	n/a	chrI 11,307,702	contains similarity to Pfam domain PF05699 hAT family dimerisation domain contains similarity to Interpro domains IPR001300 (Peptidase C2, calpain), IPR008906 (HAT dimerisation)
22	che-12	B0024.8	n/a	chrV 10,303,399	che-12 encodes a conserved protein that contains at least seven predicted HEAT repeats; CHE-12 activity is required continuously in sensory neurons for formation of distal ciliary segments and thus, for normal sensory cilium morphology and function and chemotaxis to a subset of attractants, including sodium chloride; a che-12::gfp promoter fusion is expressed in the two phasmid neurons and the subset of amphid neurons that contain relatively simple cilia; a CHE-12::GFP protein localizes to cilia in a manner suggesting that it requires intraflagellar transport for proper localization, but is unlikely to be a core IFT particle component; che-12 expression in ciliated neurons is dependent upon the presence of the DAF-19 RFX transcription factor.
23	Y75B8A.6	Y75B8A.6	n/a	chrIII 12,127,086	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
24	srx-23	F31F4.2	n/a	chrV 683,114	C. elegans SRX-23 protein ;
25	C07E3.8	C07E3.8	n/a	chrII 10,352,798	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
26	str-57	T06C12.2	n/a	chrV 15,871,734	C. elegans STR-57 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	hhat-2	Y57G11C.17	n/a	chrIV 14,827,743	C. elegans HHAT-2 protein; contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
28	C17C3.9	C17C3.9	n/a	chrII 5,531,799
29	C17H1.6	C17H1.6	n/a	chrI 13,131,624	contains similarity to Danio rerio Arginine and glutamate-rich protein 1-B.; SW:Q6P5L7
30	F45F2.6	F45F2.6	n/a	chrV 8,527,305	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
31	Y62H9A.3	Y62H9A.3	n/a	chrX 11,879,462	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000480 (Glutelin)
32	hlh-10	ZK682.4	n/a	chrV 9,281,043	C. elegans HLH-10 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
33	srh-7	K09D9.7	n/a	chrV 4,009,007	C. elegans SRH-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	C55B6.5	C55B6.5	n/a	chrX 7,205,013	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
35	fbxa-41	F52D2.1	n/a	chrX 1,949,939	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
36	hlh-27	C17C3.10	n/a	chrII 5,540,531	C. elegans HLH-27 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
37	D1065.3	D1065.3	n/a	chrV 4,060,947	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
38	F57C9.6	F57C9.6	n/a	chrI 4,823,394	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
39	jkk-1	F35C8.3	n/a	chrX 5,370,204	jkk-1 encodes a member of the MAP kinase kinase superfamily that affects synaptic vesicle localization and is required in type-D motor neurons for normal locomotion; can function in the Hog1 MAP kinase pathway I in yeast as an activator of JNK and is expressed in most neurons
40	clec-244	T27C5.7	n/a	chrV 17,414,115	C. elegans CLEC-244 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
41	F29A7.8	F29A7.8	n/a	chrII 2,757,825	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
42	Y62H9A.10	Y62H9A.10	n/a	chrX 11,901,221	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
43	sra-17	F28C12.1	n/a	chrI 12,689,638	C. elegans SRA-17 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
44	tsp-8	F33C8.3	n/a	chrX 14,727,975	tsp-8 is orthologous to the human gene KANGAI 1 (SUPPRESSION OF TUMORIGENICITY 6, PROSTATE; CD82 ANTIGEN (R2 LEUKOCYTE ANTIGEN, ANTIGEN DETECTED BY MONOCLONAL AND ANTIBODY IA4)) (KAI1; OMIM:600623), which when mutated leads to disease.
45	C31B8.2	C31B8.2	n/a	chrV 2,917,112	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
46	T05C1.1	T05C1.1	n/a	chrII 4,479,688
47	fbxa-153	B0391.5	n/a	chrV 15,608,029	fbxa-153 encodes a protein with an N-terminal F-box domain and a C-terminal FTH domain; FBXA-153 has no obvious non-nematode orthologs; FBXA-153 shares N-terminal UNC-13 binding, and thus may share at least some functions, with ERI-1, W04D2.6, and Y55F3AM.13; FBXA-153 has no obvious function in mass RNAi assays.
48	pqn-2	AC3.4	n/a	chrV 10,383,199	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
49	K04A8.3	K04A8.3	n/a	chrV 6,559,849
50	F59E10.3	F59E10.3	n/a	chrII 10,873,252	F59E10.3 encodes a zeta subunit of the coatomer (COPI) complex; in mass RNAi assays, F59E10.3 is required for embryonic, larval, and adult viability, for fertility, and for normal osmoregulation.