UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T20H12.1	T20H12.1	7e-92	chrII 3,950,365
2	F59B2.11	F59B2.11	n/a	chrIII 9,014,893	contains similarity to Homo sapiens hypothetical protein; VG:OTTHUMP00000025312
3	C50H11.17	C50H11.17	n/a	chrV 3,097,908	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
4	C04C3.6	C04C3.6	n/a	chrIV 3,421,207	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
5	gcy-37	C54E4.3	n/a	chrIV 2,154,905	gcy-37 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-37 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-37 in C. elegans development and/or behavior is not yet known; GCY-37 expression in neurons connected to the pseudocoelom suggests, however, that GCY-37 may play a role in fluid homeostasis.
6	dmd-3	Y43F8C.10	n/a	chrV 19,652,807	C. elegans DMD-3 protein; contains similarity to Pfam domain PF00751 DM DNA binding domain contains similarity to Interpro domain IPR001275 (DM DNA-binding)
7	Y54E2A.2	Y54E2A.2	n/a	chrII 14,750,101	contains similarity to Interpro domain IPR003593 (AAA+ ATPase, core)
8	gcy-23	T26C12.4	n/a	chrIV 3,286,107	gcy-23 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-18, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-23 functions redundantly with gcy-8 and gcy-18, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, loss of gcy-23 activity via RNAi results in lifespan extension; GCY-23 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
9	srh-298	Y94A7B.5	n/a	chrV 17,819,902	C. elegans SRH-298 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	str-129	F58G4.5	n/a	chrV 8,091,709	C. elegans STR-129 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	rrf-3	F10B5.7	n/a	chrII 8,165,532	rrf-3 encodes an RNA-directed RNA polymerase (RdRP) homolog that inhibits somatic RNAi, and thus promotes activity of repeated genes (e.g., multicopy transgenic arrays); the effect of RRF-3 on RNAi is opposite to that of RRF-1 (which stimulates somatic RNAi), which might arise from competition by RRF-3 with RRF-1 or EGO-1 in RNAi formation; rrf-3(allele) or rrf-3(allele2) mutants are hypersensitive to somatic RNAi, and conversely suppress the activity of an integrated rol6 (su1006) transgene.
12	Y43F8C.13	Y43F8C.13	n/a	chrV 19,691,051	contains similarity to Pfam domain PF01156 Inosine-uridine preferring nucleoside hydrolase contains similarity to Interpro domain IPR001910 (Inosine/uridine-preferring nucleoside hydrolase)
13	Y75B8A.6	Y75B8A.6	n/a	chrIII 12,127,086	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
14	F32B5.2	F32B5.2	n/a	chrI 2,698,698
15	T24A6.16	T24A6.16	n/a	chrV 3,562,186	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
16	str-109	F10A3.5	n/a	chrV 16,161,427	C. elegans STR-109 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	math-5	C16C4.10	n/a	chrII 1,882,210	C. elegans MATH-5 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
18	ZK1055.5	ZK1055.5	n/a	chrV 6,582,618	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
19	clec-92	Y52B11A.5	n/a	chrI 11,016,484	C. elegans CLEC-92 protein; contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
20	K05G3.2	K05G3.2	n/a	chrX 16,497,319
21	C26B2.5	C26B2.5	n/a	chrIV 8,040,889
22	clec-195	Y116A8C.21	n/a	chrIV 17,044,558	C. elegans CLEC-195 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	F38C2.1	F38C2.1	n/a	chrIV 16,249,570	contains similarity to Carnobacterium piscicola ATP-dependent translocator.; TR:Q46317
24	T07D3.2	T07D3.2	n/a	chrII 902,779	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
25	Y48A6B.9	Y48A6B.9	n/a	chrIII 11,034,508	contains similarity to Pfam domain PF08240 Alcohol dehydrogenase GroES-like domain contains similarity to Interpro domains IPR011032 (GroES-like), IPR013154 (Alcohol dehydrogenase GroES-like), IPR002085 (Alcohol dehydrogenase superfamily, zinc-containing), IPR016040 (NAD(P)-binding)
26	R12B2.2	R12B2.2	n/a	chrIII 5,808,424	contains similarity to Homo sapiens Isoform 1 of Golgin-45; ENSEMBL:ENSP00000327541
27	Y7A5A.7	Y7A5A.7	n/a	chrX 15,802,663	contains similarity to Murine herpesvirus 72 Membrane virion glycoprotein 150.; TR:Q9DYE3
28	srab-6	C36C5.10	n/a	chrV 3,151,224	C. elegans SRAB-6 protein ;
29	srt-2	Y45G12C.5	n/a	chrV 2,545,033	C. elegans SRT-2 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
30	T23G11.1	T23G11.1	n/a	chrI 7,701,721	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8I452
31	T15B7.8	T15B7.8	n/a	chrV 6,822,465	contains similarity to Ostreococcus tauri Predicted CDS, putative cytoplasmic protein family member, with ascoiled coil-4 domain, of ancient origin (ISS).; TR:Q010X5
32	srz-23	F58E2.9	n/a	chrIV 3,454,195	C. elegans SRZ-23 protein ;
33	D2045.7	D2045.7	n/a	chrIII 10,480,900	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
34	F36A2.2	F36A2.2	n/a	chrI 8,803,215	contains similarity to Pfam domain PF01207 Dihydrouridine synthase (Dus) contains similarity to Interpro domains IPR013785 (Aldolase-type TIM barrel), IPR001269 (Dihydrouridine synthase, DuS)
35	srx-23	F31F4.2	n/a	chrV 683,114	C. elegans SRX-23 protein ;
36	F43B10.1	F43B10.1	n/a	chrX 16,662,035
37	F41E6.8	F41E6.8	n/a	chrV 8,600,475	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
38	Y7A5A.2	Y7A5A.2	n/a	chrX 15,772,148	contains similarity to Aquifex aeolicus Hypothetical protein AQ_372.; SW:Y372_AQUAE
39	C40A11.5	C40A11.5	n/a	chrII 2,134,686	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
40	srx-118	T21B4.12	n/a	chrII 12,526,763	C. elegans SRX-118 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
41	F28C6.5	F28C6.5	n/a	chrII 8,599,990	contains similarity to Mus musculus Activity-dependent neuroprotector (Activity-dependent neuroprotectivesprotein).; SW:ADNP_MOUSE
42	str-14	T08G3.2	n/a	chrV 16,454,252	C. elegans STR-14 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	C54H2.4	C54H2.4	n/a	chrX 5,768,086
44	Y50F7A.2	Y50F7A.2	n/a	chrII 1,183,626
45	lgc-38	F11H8.2	n/a	chrIII 7,014,295	F11H8.2 encodes an UNC-49-like GABA receptor subunit.
46	T26C11.4	T26C11.4	n/a	chrX 1,843,047	contains similarity to Dictyostelium discoideum Similar to Homo sapiens (Human). Dentin sialophosphoprotein [Contains:sDentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentinssialoprotein (DSP)].; TR:Q869X8
47	str-38	T23D5.2	n/a	chrV 15,731,518	C. elegans STR-38 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	nph-4	R13H4.1	n/a	chrV 11,837,428	nph-4 encodes an ortholog of human NPHP4 (OMIM:607215, mutated in juvenile nephronophthisis and Senior-Loken syndrome-4) that is required for normal chemotaxis, lifespan, and male mating behavior; NPH-4 is expressed in diverse neurons (amphid and phasmid sensory, URX, labial, male lumbar and cloacal ganglia, and male-specific CEM, HOB and RnB); within neurons, NPH-4 is a ciliary protein, localized to the transistion zone at cilial bases rather than ciliary axonemes, and absent from somata, axons, or dendrites; NPH-4 colocalizes with NPH-1 and PKD-2 in male-specific sensory cilia, and is required for the normal ciliary localization of NPH-1; NPH-4 expression requires DAF-19, and mutating an X-box in nph-4's promoter abolishes nph-4 expression; NPH-4 is required for NPH-1's localization to transistion zones; morphologically, nph-4 mutant cilia are normal, indicating a function for NPH-4 in signal transduction.
49	sra-30	Y40H7A.6	n/a	chrIV 15,197,622	C. elegans SRA-30 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
50	zig-8	Y39E4B.8	n/a	chrIII 13,126,726	zig-8 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-8::gfp reporter fusion is expressed in the PVT neuron and in pharyngeal muscle.