UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	epac-1	T20G5.5	0	chrIII 10,191,417	C. elegans EPAC-1 protein; contains similarity to Pfam domains PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin) , PF00027 (Cyclic nucleotide-binding domain) (2), PF00617 (RasGEF domain) , PF00618 (Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif) contains similarity to Interpro domains IPR008937 (Ras guanine nucleotide exchange factor), IPR011051 (Cupin, RmlC-type), IPR001895 (Guanine-nucleotide dissociation stimulator CDC25), IPR011991 (Winged helix repressor DNA-binding), IPR000595 (Cyclic nucleotide-binding), IPR002373 (cAMP/cGMP-dependent protein kinase), IPR014710 (RmlC-like jelly roll fold), IPR000651 (Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal), IPR000591 (Pleckstrin/ G-protein, interacting region)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F26D11.4	F26D11.4	n/a	chrV 7,947,903
4	srh-46	T03F7.3	n/a	chrV 11,302,223	C. elegans SRH-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	F35C8.8	F35C8.8	n/a	chrX 5,373,263
6	nhl-1	F54G8.4	n/a	chrIII 9,150,557	The nhl-1 gene encodes an RBCC protein, orthologous to the mammalian protein BERP; its C. elegans paralogs include ncl-1 and lin-41.
7	T07D10.2	T07D10.2	n/a	chrI 12,622,116	T07D10.2 is orthologous to the human gene VASOPRESSIN RECEPTOR TYPE 2 (AVPR2; OMIM:304800), which when mutated leads to nephrogenic diabetes insipidus.
8	K07E8.5	K07E8.5	n/a	chrII 652,962	K07E8.5 encodes a homolog of the functionally active Fmrf Receptor (FR; CG2114) of D. melanogaster; it is thus possible that K07E8.5 is a receptor for one of the FMRF-like neurotransmitters in C. elegans (e.g., FLP-1 through FLP-12).
9	tax-4	ZC84.2	n/a	chrIII 9,183,509	tax-4 is orthologous to the human gene ROD PHOTORECEPTOR CGMP-GATED CHANNEL (CNGA1; OMIM:123825), which when mutated leads to disease.
10	sre-55	C50E10.7	n/a	chrII 12,330,123	C. elegans SRE-55 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
11	H10E21.4	H10E21.4	n/a	chrIII 18,471	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR003299 (Flagellar calcium-binding protein (calflagin))
12	gly-16	T15D6.2	n/a	chrI 12,380,173	gly-16 encodes a protein similar to 2/I N-acetylglucosaminyltransferase; gly-16 is expressed in the seam cells during embryonic stages.
13	gcy-14	ZC412.2	n/a	chrV 14,865,514	gcy-14 encodes a predicted transmembrane guanylyl cyclase; the precise role of GCY-14 in C. elegans development and/or behavior is not yet known; however, by sequence similarity GCY-14 can be predicted to function in chemosensory signal transduction.
14	gtl-2	F54D1.5	n/a	chrIV 11,277,712	gtl-2 encodes a predicted receptor-activated calcium channel and represents a family of calcium channels, the other two family members being gtl-1 and gon-2.
15	twk-36	R12G8.2	n/a	chrV 17,745,322	C. elegans TWK-36 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
16	C04F12.1	C04F12.1	n/a	chrI 9,676,100	contains similarity to Pfam domain PF02171 Piwi domain contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
17	fbxa-111	Y102A5C.14	n/a	chrV 16,949,135	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
18	C31E10.8	C31E10.8	n/a	chrX 14,007,275	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domains IPR000195 (RabGAP/TBC), IPR011046 (WD40 repeat-like), IPR002011 (Receptor tyrosine kinase, class II, conserved site)
19	ZK1128.7	ZK1128.7	n/a	chrIII 10,137,921	contains similarity to Pfam domain PF00011 Hsp20/alpha crystallin family contains similarity to Interpro domains IPR002068 (Heat shock protein Hsp20), IPR008978 (HSP20-like chaperone), IPR001436 (Alpha crystallin/Heat shock protein)
20	egl-2	F16B3.1	n/a	chrV 1,294,353	egl-2 encodes a voltage-gated potassium channel that affects egg laying, muscle activation, defecation, mechanosensation, and chemosensation; expressed in the intestinal muscle, AFD, ALN, AQR, ASE, AWC, BAG, IL2, PLN, PQR, and URX neurons as well as a subset of sensory neurons in the male tail.
21	srt-34	F54E2.6	n/a	chrV 2,817,549	C. elegans SRT-34 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
22	T19D2.3	T19D2.3	n/a	chrX 3,939,726
23	T11F9.1	T11F9.1	n/a	chrV 11,460,688	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
24	F13E9.8	F13E9.8	n/a	chrIV 10,893,972	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
25	srh-207	ZK262.1	n/a	chrV 18,409,607	C. elegans SRH-207 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	C09G1.2	C09G1.2	n/a	chrX 15,980,318	contains similarity to Saccharomyces cerevisiae Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1; SGD:YNL271C
27	ZK1055.4	ZK1055.4	n/a	chrV 6,586,468	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
28	C54E10.2	C54E10.2	n/a	chrV 18,829,031	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
29	F27E5.5	F27E5.5	n/a	chrII 10,129,961	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
30	srx-88	F43A11.1	n/a	chrV 11,584,291	C. elegans SRX-88 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR001991 (Sodium:dicarboxylate symporter)
31	T07G12.4	T07G12.4	n/a	chrIV 10,537,682	contains similarity to Pfam domain PF00860 Permease family contains similarity to Interpro domain IPR006043 (Xanthine/uracil/vitamin C permease)
32	ZC482.4	ZC482.4	n/a	chrIII 12,766,680	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
33	T22H6.1	T22H6.1	n/a	chrX 12,768,557	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
34	M02B7.5	M02B7.5	n/a	chrIV 3,813,489	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) , PF01369 (Sec7 domain) contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR000904 (SEC7-like)
35	ZK688.1	ZK688.1	n/a	chrIII 7,910,130
36	C25A1.12	C25A1.12	n/a	chrI 10,192,090	contains similarity to Pfam domain PF00561 alpha/beta hydrolase fold contains similarity to Interpro domains IPR000073 (Alpha/beta hydrolase fold-1), IPR003089 (Alpha/beta hydrolase), IPR002410 (Peptidase S33, prolyl aminopeptidase)
37	nhr-186	F47C10.3	n/a	chrV 3,853,607	C. elegans NHR-186 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
38	F27D9.7	F27D9.7	n/a	chrX 7,667,592	contains similarity to Pfam domain PF01421 Reprolysin (M12B) family zinc metalloprotease contains similarity to Interpro domain IPR001590 (Peptidase M12B, ADAM/reprolysin)
39	D1046.4	D1046.4	n/a	chrIV 8,935,680	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
40	C17B7.5	C17B7.5	n/a	chrV 3,336,321	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domains IPR002345 (Lipocalin), IPR006588 (Protein of unknown function PAW)
41	T28F2.7	T28F2.7	n/a	chrI 3,658,340	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR001873 (Na+ channel, amiloride-sensitive)
42	lgc-45	W10G11.16	n/a	chrII 3,566,681	C. elegans LGC-45 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
43	sre-7	K02E11.2	n/a	chrV 14,245,132	C. elegans SRE-7 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
44	nspb-5	F38A5.9	n/a	chrIV 6,599,329	C. elegans NSPB-5 protein; contains similarity to Pfam domain PF07312 Protein of unknown function (DUF1459) contains similarity to Interpro domain IPR009924 (Protein of unknown function DUF1459)
45	K03H1.8	K03H1.8	n/a	chrIII 9,945,970	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domain IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type)
46	pqn-29	F10F2.9	n/a	chrIII 4,645,137	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
47	srx-67	K07C6.10	n/a	chrV 3,917,627	C. elegans SRX-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
48	C49D10.4	C49D10.4	n/a	chrII 3,871,448	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
49	T07C12.10	T07C12.10	n/a	chrV 9,960,139	contains similarity to Rattus norvegicus Trans-Golgi network integral membrane protein TGN38 precursor.; SW:TGN3_RAT
50	grl-12	F28A12.2	n/a	chrV 8,636,381	grl-12 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.