UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T20F7.6	T20F7.6	0	chrX 16,867,473	contains similarity to Pfam domain PF00571 CBS domain pair contains similarity to Interpro domain IPR000644 (Cystathionine beta-synthase, core)
2	math-14	C16C4.4	n/a	chrII 1,870,071	C. elegans MATH-14 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR001712 (Type III secretion system FHIPEP)
3	C05G5.3	C05G5.3	n/a	chrX 14,751,355	contains similarity to Homo sapiens Isoform 1 of Matrix-remodeling-associated protein 7; ENSEMBL:ENSP00000348050
4	unc-122	F11C3.2	n/a	chrI 14,873,757	unc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known.
5	sor-3	C04E7.2	n/a	chrX 355,777	sor-3 encodes a novel protein that contains an MBT (malignant brain tumor) domain related to the MBT domains found in the Sex comb on midleg (SCM) and Sfmbt Polycomb group proteins; during development, SOR-3 activity is required to specify the correct number of dopaminergic and serotonergic neurons in males, as well as for proper ray neuron axon guidance, distal tip cell migration, and normal body size; SOR-3 activity is necessary for maintaining repression of Hox gene expression, notably that of egl-5 in many head neurons; in regulating neurotransmitter phenotype, sor-3 functions together with sop-2, which also encodes a Polycomb group protein, and members of the TGF-beta signaling pathway; sor-3 and sop-2 also function together to regulate progression through larval development; a SOR-3::GFP reporter fusion is expressed ubiquitously throughout the life cycle and localizes to both the cytoplasm and the nucleus.
6	col-56	T08B2.2	n/a	chrI 6,233,530	C. elegans COL-56 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
7	set-10	F33H2.7	n/a	chrI 15,029,120	set-10 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-10 is paralogous to SET-14, SET-18, and SET-30; SET-10 has no obvious function in individual RNAi assays of vulval development, or in mass RNAi assays.
8	hpl-1	K08H2.6	n/a	chrX 13,246,140	hpl-1 encodes one of two C. elegans heterochromatin protein 1 (HP1) homologs; loss of hpl-1 activity alone results in no obvious defects, but animals doubly mutant for hpl-1 and hpl-2 have defects in larval, somatic gonad and germline development; in addition, hpl-1 functions redundantly with hpl-2 and lin-13 in vulval development; rescuing HPL-1::GFP fusion proteins are expressed in nuclei throughout the life cycle, beginning at approximately the 50-cell stage of embryogenesis and continuing through larval and adult stages; expression is observed in most, but not all, cells and is particularly strong in head and tail hypodermal and neuronal nuclei; in nuclei, HPL-1::GFP is seen in foci that do not significantly overlap with those of HPL-2.
9	Y45F10B.12	Y45F10B.12	n/a	chrIV 13,587,824	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
10	C30G4.6	C30G4.6	n/a	chrX 17,077,020	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
11	C09B8.5	C09B8.5	n/a	chrX 6,021,639
12	W01C9.1	W01C9.1	n/a	chrII 8,533,713	contains similarity to Brugia pahangi Heat shock protein 90.; SW:HS90_BRUPA
13	F31A3.5	F31A3.5	n/a	chrX 17,558,148	contains similarity to Interpro domain IPR000694 (Proline-rich region)
14	R07B1.9	R07B1.9	n/a	chrX 9,879,387	contains similarity to Arabidopsis thaliana Hypothetical protein (At1g15170).; TR:Q8L731
15	cnd-1	C34E10.7	n/a	chrIII 5,241,308	cnd-1 encodes a basic helix-loop-helix protein that is most closely related to the vertebrate NeuroD transcription factors; during development, CND-1 is predicted to function as a transcriptional regulator whose activity is required for several aspects of motor neuron fate specification, including cell division patterns, proper spatiotemporal expression of fate-specific markers, and normal axonal morphology and pathfinding; CND-1::GFP expression begins in early embryogenesis (<20 cells) in four AB descendants and then continues in mitotically active AB-derived neuronal precursors, unidentified nuclei during gastrulation and enclosure, and postmitotic neurons in the head and ventral cord; at hatching CND-1::GFP expression is visible in ventral cord neurons, but this expression disappears completely by the end of the first larval stage; CND-1::GFP does not appear to be expressed in any non-neuronal ectodermal cells, as its expression does not overlap with that of LIN-26.
16	T22C8.3	T22C8.3	n/a	chrII 8,621,191	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
17	fbxb-50	K05F6.2	n/a	chrII 1,559,901	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
18	F25D1.4	F25D1.4	n/a	chrV 10,543,032	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
19	F07H5.6	F07H5.6	n/a	chrII 8,792,268	contains similarity to Interpro domain IPR002952 (Eggshell protein)
20	lin-8	B0454.1	n/a	chrII 3,058,509	lin-8 is a class A synthetic multivulva (synMuv) gene that functions redundantly with class B synMuv genes to negatively regulate Ras-mediated signaling during vulval induction.
21	mec-6	W02D3.3	n/a	chrI 6,726,624	mec-6 is homologous to the human PARAOXONASE 1 gene (PON1, OMIM:168820), which in some allelic forms is associated with susceptibility to coronary artery disease; MEC-6 protein interacts physically with the MEC-4 degenerin ion channel, is colocalized with it in vivo, and is required for MEC-4 punctate expression along touch-receptor neural processes.
22	F55F8.3	F55F8.3	n/a	chrI 5,651,700	contains similarity to Pfam domains PF04047 (Periodic tryptophan protein 2 WD repeat associated presumed domain) , PF00400 (WD domain, G-beta repeat) (5)contains similarity to Interpro domains IPR000009 (Protein phosphatase 2A, regulatory subunit PR55), IPR017441 (Protein kinase ATP binding, conserved site), IPR011046 (WD40 repeat-like), IPR007190 (Periodic tryptophan protein-associated region), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
23	srt-13	ZC142.1	n/a	chrV 4,249,044	C. elegans SRT-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000539 (Frizzled protein)
24	osm-10	T20H4.1	n/a	chrIII 7,244,451	osm-10 encodes a novel protein conserved amongst several Caenorhabditis species; osm-10 activity is required for normal osmosensory signaling in the ASH sensory neuron; in regulating ASH-mediated osmosensation, osm-10 interacts genetically with eos-1 and eos-2; OSM-10 is expressed in the ASH, ASI, PHA, and PHB sensory neurons beginning just prior to hatching and continuing through larval and adult stages; OSM-10 localizes to cell bodies, sensory processes, and axons.
25	T07F12.2	T07F12.2	n/a	chrX 4,891,246	contains similarity to Pfam domain PF02225 PA domain contains similarity to Interpro domain IPR003137 (Protease-associated PA)
26	srj-21	F28H7.11	n/a	chrV 10,745,530	C. elegans SRJ-21 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	F52D2.6	F52D2.6	n/a	chrX 1,977,920
28	T22B2.3	T22B2.3	n/a	chrX 3,919,045
29	ugt-56	T04H1.8	n/a	chrV 12,260,070	C. elegans UGT-56 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
30	cdh-4	F25F2.2	n/a	chrIII 4,528,691	A homolog of a member of the cadherin superfamily that is involved in cell-cell adhesion.
31	cdh-8	F18F11.3	n/a	chrIV 351,612	cdh-8 encodes a cadherin that may be nematode specific; CDH-8 is predicted to function as a membrane protein that plays a role in cell adhesion and/or morphogenesis, but as loss of cdh-8 activity via mutation or large-scale RNAi experiments results in no obvious abnormalities, the precise role of cdh-8 in C. elegans development and/or behavior is not yet known.
32	srab-13	F59A7.3	n/a	chrV 2,026,295	C. elegans SRAB-13 protein ;
33	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
34	cal-3	M02B7.6	n/a	chrIV 3,832,350	cal-3 encodes a member of the calmodulin family.
35	F55G1.1	F55G1.1	n/a	chrIV 7,492,779
36	C06E4.2	C06E4.2	n/a	chrIV 7,282,673
37	F21D5.9	F21D5.9	n/a	chrIV 8,724,343	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
38	F40G12.6	F40G12.6	n/a	chrV 14,272,120	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
39	C08G9.2	C08G9.2	n/a	chrIV 7,668,512	contains similarity to Pfam domains PF02822 (Antistasin family) (6), PF00014 (Kunitz/Bovine pancreatic trypsin inhibitor domain) , PF00095 (WAP-type (Whey Acidic Protein) 'four-disulfide core') (8), PF00086 (Thyroglobulin type-1 repeat) (6)contains similarity to Interpro domains IPR000716 (Thyroglobulin type-1), IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR008197 (Whey acidic protein, 4-disulphide core), IPR008198 (Proteinase inhibitor I17), IPR006150 (Cysteine-rich repeat), IPR013032 (EGF-like region, conserved site), IPR004094 (Proteinase inhibitor I15, antistasin), IPR015874 (4-disulphide core), IPR007087 (Zinc finger, C2H2-type), IPR003645 (Follistatin-like, N-terminal), IPR000737 (Proteinase inhibitor I7, squash)
40	K07C11.10	K07C11.10	n/a	chrV 8,226,436	contains similarity to Homo sapiens hypothetical protein isoform 1; ENSEMBL:ENSP00000381337
41	T08G5.7	T08G5.7	n/a	chrV 14,044,675	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
42	F35E2.2	F35E2.2	n/a	chrI 11,737,158	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
43	ceh-13	R13A5.5	n/a	chrIII 7,556,858	a homolog of Hox genes of labial/Hox1 type; affects viability, body shape and anterior patterning during embryogenesis, interacts genetically with hox genes; and is expressed in A, D, E and MS lineages in the early embryo, and in the anterior dorsal hypodermal cells, anterior body wall muscle cells, and in the cells of the prospective ventral nerve cord at the comma stage; and in the ventral nerve cord and and ventral and dorsal hypodermal cells in L1 larvae.
44	F52D10.6	F52D10.6	n/a	chrX 11,583,279	contains similarity to Pfam domain PF00169 PH domain contains similarity to Interpro domains IPR000219 (Dbl homology (DH) domain), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type)
45	F29F11.3	F29F11.3	n/a	chrV 10,658,900	contains similarity to Drosophila melanogaster Flybase gene name is CG10189-PA;; FLYBASE:CG10189
46	elks-1	F42A6.9	n/a	chrIV 3,346,268	elks-1 encodes the C. elegans homolog of the vertebrate ELKS (glutamine, leucine, lysine, and serine-rich) proteins; although loss of elks-1 activity results in no obvious developmental or behavioral abnormalities, the ELKS-1 C-terminus interacts with the PDZ domain of UNC-10/RIM in vitro, and in vivo each protein appears to play a nonessential role in localizing the other to the presynaptic active zone; in addition to the active zone, ELKS-1 also localizes to the pharyngeal basal lamina.
47	C49H3.9	C49H3.9	n/a	chrIV 7,908,266	contains similarity to Pfam domain PF07967 C3HC zinc finger-like contains similarity to Interpro domain IPR012935 (Zinc finger, C3HC-like)
48	D1065.1	D1065.1	n/a	chrV 4,075,636	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
49	sdz-21	F54E7.5	n/a	chrIII 5,655,941	C. elegans SDZ-21 protein; contains similarity to Interpro domain IPR000480 (Glutelin)
50	clec-11	C54C8.7	n/a	chrI 12,460,190	C. elegans CLEC-11 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF00059 (Lectin C-type domain) (2)contains similarity to Interpro domains IPR000859 (CUB), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)