UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T20D4.8	T20D4.8	0	chrV 3,406,799	T20D4.8 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T20D4.8 has no clear orthologs in other organisms.
2	F48A11.2	F48A11.2	n/a	chrII 198,605
3	clec-238	Y102A5C.17	n/a	chrV 16,952,706	C. elegans CLEC-238 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
4	R11G1.1	R11G1.1	n/a	chrX 3,663,173	contains similarity to Pfam domain PF00057 Low-density lipoprotein receptor domain class A contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
5	bli-5	F45G2.5	n/a	chrIII 13,428,598	bli-5 encodes a protease inhibitor that affects the integrity of the cuticle and the development of the bursa in the adult male.
6	C29F9.2	C29F9.2	n/a	chrIII 131,349	contains similarity to Homo sapiens Isoform 3 of MAP7 domain-containing protein 1; ENSEMBL:ENSP00000362241
7	tat-6	F02C9.3	n/a	chrV 3,131,186	C. elegans TAT-6 protein; contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006069 (ATPase, P-type cation exchange, alpha subunit), IPR006539 (Phospholipid-translocating P-type ATPase, flippase), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
8	H12D21.9	H12D21.9	n/a	chrV 14,908,258	contains similarity to Oceanobacillus iheyensis Hypothetical UPF0090 protein OB1594.; SW:YF94_OCEIH
9	btb-9	F45C12.4	n/a	chrII 1,729,278	C. elegans BTB-9 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
10	tag-294	C54H2.3	n/a	chrX 5,761,796	C. elegans TAG-294 protein; contains similarity to Pfam domain PF00641 Zn-finger in Ran binding protein and others contains similarity to Interpro domain IPR001876 (Zinc finger, RanBP2-type)
11	T11F1.6	T11F1.6	n/a	chrII 2,945,352	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
12	Y47H9C.12	Y47H9C.12	n/a	chrI 11,896,823	contains similarity to Escherichia coli O6 FMN reductase (EC 1.5.1.29).; TR:Q8FJ92
13	Y39A1A.20	Y39A1A.20	n/a	chrIII 10,699,807
14	AH10.4	AH10.4	n/a	chrV 14,137,472	contains similarity to Methanosarcina acetivorans Hypothetical protein MA1935.; TR:Q8TPH7
15	C41H7.1	C41H7.1	n/a	chrII 3,016,764
16	srw-12	C41G6.2	n/a	chrV 15,237,968	C. elegans SRW-12 protein ;
17	T23F6.2	T23F6.2	n/a	chrIV 12,722,330
18	K10C2.2	K10C2.2	n/a	chrX 6,433,006	contains similarity to Interpro domain IPR000832 (GPCR, family 2, secretin-like)
19	F53H1.1	F53H1.1	n/a	chrIV 1,303,451	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
20	Y32B12C.3	Y32B12C.3	n/a	chrV 16,613,751	contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
21	F21E9.2	F21E9.2	n/a	chrX 1,329,400
22	D1005.2	D1005.2	n/a	chrX 1,460,943	contains similarity to Pfam domain PF01704 UTP--glucose-1-phosphate uridylyltransferase contains similarity to Interpro domains IPR016267 (UTP--glucose-1-phosphate uridylyltransferase, subgroup), IPR002618 (UTP--glucose-1-phosphate uridylyltransferase)
23	F21A3.5	F21A3.5	n/a	chrV 15,540,560	contains similarity to Pfam domain PF01966 HD domain contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR006674 (Metal-dependent phosphohydrolase, HD region, subdomain)
24	C06A1.6	C06A1.6	n/a	chrII 10,564,347	contains similarity to Interpro domains IPR000006 (Metallothionein, vertebrate), IPR004035 (Endonuclease III, iron-sulphur binding, conserved site-1), IPR001396 (Echinodermata metallothionein, family 4), IPR001008 (Mollusc metallothionein, family 2)
25	srx-121	C04E12.8	n/a	chrV 3,371,855	C. elegans SRX-121 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
26	C45G9.7	C45G9.7	n/a	chrIII 5,046,619	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domains IPR017268 (Tax1-binding protein 3), IPR001478 (PDZ/DHR/GLGF)
27	D1046.3	D1046.3	n/a	chrIV 8,931,564	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier)
28	math-1	B0047.4	n/a	chrII 2,046,310	C. elegans MATH-1 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
29	rog-1	F54D12.6	n/a	chrII 1,374,343	rog-1 encodes a protein with an insulin receptor substrate-1 (IRS-type) phosphotyrosine-binding (PTB) domain that is required for the progression from pachytene to diakinesis in meiosis; rog-1 is primarily transcribed in germ cells, and this expression is required for oocyte development; ROG-1 is orthologous to human FRS2 (OMIM:607743) and FRS3 (OMIM:607744); rog-1(tm1031) mutant oocytes fail to progress from pachytene to diakinesis, a phenotype reminiscent of let-60 or mpk-1 mutant oocytes, and rog-1(tm1031) gonads lack phosphorylated MPK-1; rog-1(tm1031) and rog-1(RNAi) hermaphrodites show reduced brood sizes and increased embryonic lethality, with rog-1(tm1031) being more phenotypically severe than rog-1(RNAi); rog-1(tm1031) germ cell, brood size, and MPK-1 phosphorylation phenotypes are suppressed by the gain-of-function mutations let-60(n1046) or let-60(ga89ts); during meiosis, ROG-1 may function as an adaptor downstream of LET-23 and upstream of LET-60.
30	trxr-2	ZK637.10	n/a	chrIII 8,915,015	C. elegans TRXR-2 protein; contains similarity to Pfam domains PF02852 (Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain) , PF07992 (Pyridine nucleotide-disulphide oxidoreductase) , PF00070 (Pyridine nucleotide-disulphide oxidoreductase) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000447 (FAD-dependent glycerol-3-phosphate dehydrogenase), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR012999 (Pyridine nucleotide-disulphide oxidoreductase, class I, active site), IPR004099 (Pyridine nucleotide-disulphide oxidoreductase, dimerisation), IPR006338 (Thioredoxin and glutathione reductase selenoprotein), IPR016156 (FAD/NAD-linked reductase, dimerisation), IPR001327 (Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region), IPR000815 (Mercuric reductase), IPR016040 (NAD(P)-binding), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
31	fbxa-113	Y113G7B.6	n/a	chrV 20,199,350	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
32	lin-25	F56H9.5	n/a	chrV 12,654,300	lin-25 encodes a novel transcription factor that is conserved in C. briggsae and C. remanei; during development, lin-25 functions downstream of let-60 ras to regulate fate specification and differentiation of a number of cell types such as the vulval precursor cells; targets of LIN-25 activity include the lin-39 Hox gene, whose transcriptional upregulation during vulval cell fate specification is dependent upon lin-25; LIN-25 is expressed in vulval precursor cells, hypodermal seam cells, and cells in the somatic gonad; LIN-25 is detected in nuclei, but also seen in the cytoplasm.
33	srsx-22	F38E1.8	n/a	chrV 8,352,357	C. elegans SRSX-22 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
34	ztf-8	ZC395.8	n/a	chrIII 5,271,035	C. elegans ZTF-8 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR004355 (Type IV secretion system CagA exotoxin), IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
35	nhr-230	Y17D7A.1	n/a	chrV 18,849,704	C. elegans NHR-230 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
36	sdz-15	F23F12.4	n/a	chrIII 6,499,273	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
37	F54E4.4	F54E4.4	n/a	chrX 14,643,359	contains similarity to Pfam domain PF03931 Skp1 family, tetramerisation domain contains similarity to Interpro domains IPR001232 (SKP1 component), IPR011333 (BTB/POZ fold), IPR016073 (SKP1 component, POZ)
38	nol-9	K09B11.2	n/a	chrIV 13,425,891	C. elegans NOL-9 protein; contains similarity to Pfam domain PF08160 NUC156 domain contains similarity to Interpro domains IPR012581 (NUC156), IPR003593 (AAA+ ATPase, core)
39	M01B2.8	M01B2.8	n/a	chrV 15,260,488	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
40	C14E2.1	C14E2.1	n/a	chrX 1,826,905
41	K02F3.8	K02F3.8	n/a	chrIII 838,968
42	gpa-4	T07A9.7	n/a	chrIV 403,531	gpa-4 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ASI.
43	hap-1	ZC395.7	n/a	chrIII 5,264,428	C. elegans HAP-1 protein; contains similarity to Pfam domain PF01725 Ham1 family contains similarity to Interpro domain IPR002637 (Ham1-like protein)
44	D1005.6	D1005.6	n/a	chrX 1,463,763
45	C07D8.2	C07D8.2	n/a	chrX 7,362,559	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
46	T02G5.1	T02G5.1	n/a	chrII 7,098,996
47	F49C12.2	F49C12.2	n/a	chrIV 9,298,599	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
48	W03H9.3	W03H9.3	n/a	chrII 14,143,131	contains similarity to Streptomyces avermitilis Putative oxidoreductase.; TR:Q82DU1
49	F02E9.1	F02E9.1	n/a	chrI 8,407,250	F02E9.1 encodes a divergent ortholog of S. cerevisiae VMA22; like VMA22, F02E9.1 may be required for vacuolar proton-translocating ATPase (V-ATPase) assembly in the endoplasmic reticulum.
50	rab-33	F43D9.2	n/a	chrIII 10,501,953	C. elegans RAB-33 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR000694 (Proline-rich region), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)