UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T20D4.13	T20D4.13	3.0000000000000003e-128	chrV 3,392,486
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	ver-4	F59F3.5	n/a	chrX 10,985,087	C. elegans VER-4 protein; contains similarity to Pfam domains PF07686 (Immunoglobulin V-set domain) , PF00047 (Immunoglobulin domain) (2), PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF07679 (Immunoglobulin I-set domain) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR013098 (Immunoglobulin I-set), IPR011009 (Protein kinase-like), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR000719 (Protein kinase, core), IPR013106 (Immunoglobulin V-set), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site), IPR013151 (Immunoglobulin)
4	tag-236	R11B5.1	n/a	chrX 2,528,819	C. elegans TAG-236 protein; contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
5	grl-6	K10C2.5	n/a	chrX 6,450,444	grl-6 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-6 is expressed in larval intestine, amphid socket cells, and neurons; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
6	ptr-13	K07C10.1	n/a	chrII 11,159,735	ptr-13 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-13 is weakly required for normal molting from L4 to adult stages; PTR-13 is also required for normal growth to full size and locomotion.
7	Y47H9C.9	Y47H9C.9	n/a	chrI 11,900,113	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
8	M153.3	M153.3	n/a	chrX 12,143,295	contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
9	apx-1	K08D9.3	n/a	chrV 3,216,670	apx-1 encodes one of ten C. elegans DSL (Delta, Serrate, LAG-2) proteins, integral transmembrane and secreted proteins that function as signaling ligands for the Notch family receptors GLP-1 and LIN-12; in the 4-cell embryo, maternally supplied APX-1 functions as a GLP-1 ligand for an inductive interaction that specifies the fate of the ABp blastomere; later in embryogenesis, APX-1 is required for formation of the LIN-12-dependent, invariant asymmetrical twist that occurs as part of normal gut morphogenesis; during larval development, APX-1 is required redundantly with DSL-1 and LAG-2 for the LIN-12-mediated lateral signal that spatially patterns the primary and secondary vulval cell lineages; in the early embryo, APX-1 is first detected at the anterior edge of the P1 blastomere, with later expression visible in P2 at sites of contact with ABp, and in the cytoplasm of the EMS and P3 blastomeres; expression in the vulval precursor cells (VPCs) is detected in the primary VPC, P6.p, and its descendants; embryonic APX-1 expression is dependent upon PIE-1 activity, while later vulval expression is mediated by the Ras signaling pathway and the SUR-2 transcriptional cofactor.
10	str-122	W03D2.10	n/a	chrIV 4,067,151	C. elegans STR-122 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	srh-266	F31F4.6	n/a	chrV 665,362	C. elegans SRH-266 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	prx-6	F39G3.7	n/a	chrV 4,717,742	C. elegans PRX-6 protein; contains similarity to Pfam domain PF00004 ATPase family associated with various cellular activities (AAA) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal)
13	C03F11.2	C03F11.2	n/a	chrX 5,395,712	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
14	str-85	F59E11.15	n/a	chrV 8,985,157	C. elegans STR-85 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	math-15	C16C4.5	n/a	chrII 1,867,089	C. elegans MATH-15 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
16	fbxa-166	C08E3.9	n/a	chrII 1,617,962	C. elegans FBXA-166 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
17	nhr-181	F38H12.3	n/a	chrV 4,097,665	nhr-181 encodes a putative nuclear hormone receptor (NHR), belonging to a large nematode-specific expanded family of NHRs, that inhibits CEP-1- and HUS-1-dependent germline apoptosis as do BMK-1, RAD-50, and RAD-51.
18	T26C12.2	T26C12.2	n/a	chrIV 3,264,607	contains similarity to Interpro domain IPR001991 (Sodium:dicarboxylate symporter)
19	nas-18	K03B8.3	n/a	chrV 11,396,823	nas-18 encodes an astacin-like metalloprotease; loss of nas-18 activity via RNAi results in a reduction of fat content suggesting an abnormality in lipid metabolism.
20	R53.2	R53.2	n/a	chrII 9,964,971	contains similarity to Pfam domain PF02223 Thymidylate kinase contains similarity to Interpro domain IPR000062 (Thymidylate kinase)
21	F02E9.1	F02E9.1	n/a	chrI 8,407,250	F02E9.1 encodes a divergent ortholog of S. cerevisiae VMA22; like VMA22, F02E9.1 may be required for vacuolar proton-translocating ATPase (V-ATPase) assembly in the endoplasmic reticulum.
22	T06E6.10	T06E6.10	n/a	chrV 15,418,719	contains similarity to Pfam domain PF01826 Trypsin Inhibitor like cysteine rich domain contains similarity to Interpro domains IPR002919 (Protease inhibitor I8, cysteine-rich trypsin inhibitor-like), IPR013032 (EGF-like region, conserved site)
23	F59A2.2	F59A2.2	n/a	chrIII 3,408,380	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EN31
24	srx-16	T07H8.1	n/a	chrV 6,976,849	C. elegans SRX-16 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
25	srg-59	C24B9.7	n/a	chrV 2,724,113	C. elegans SRG-59 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
26	C04E12.5	C04E12.5	1e-18	chrV 3,359,866	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
27	C28G1.4	C28G1.4	n/a	chrX 8,851,319	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
28	C34B2.9	C34B2.9	n/a	chrI 10,701,670	contains similarity to Interpro domain IPR001904 (Paxillin)
29	sri-31	B0454.2	n/a	chrII 3,051,657	C. elegans SRI-31 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	nhr-165	C47F8.2	n/a	chrI 12,332,239	C. elegans NHR-165 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
31	ugt-10	T19H12.11	n/a	chrV 4,899,135	C. elegans UGT-10 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
32	K03D10.3	K03D10.3	n/a	chrI 14,122,952	The K03D10.3 gene encodes a MYST acetyltransferase orthologous to the Drosophila MALES-ABSENT-ON-THE-FIRST (MOF) and CG1894 proteins, the human MOF protein, and the S. cerevisiae SAS2 protein.
33	nas-1	F45G2.1	n/a	chrIII 13,407,525	nas-1 encodes an astacin-like metalloprotease.
34	F52C12.4	F52C12.4	n/a	chrIV 1,934,886	contains similarity to Pfam domains PF01535 (PPR repeat) , PF02141 (DENN (AEX-3) domain) , PF03456 (uDENN domain) , PF03455 (dDENN domain) contains similarity to Interpro domains IPR005112 (dDENN), IPR012336 (Thioredoxin-like fold), IPR005113 (uDENN), IPR002885 (Pentatricopeptide repeat), IPR001194 (DENN)
35	R12B2.3	R12B2.3	n/a	chrIII 5,806,220
36	immp-1	C24H11.6	n/a	chrIII 11,775,731	C. elegans IMMP-1 protein; contains similarity to Pfam domain PF00717 Peptidase S24-like contains similarity to Interpro domains IPR001733 (Peptidase S26B, eukaryotic signal peptidase), IPR015927 (Peptidase S24, S26A, S26B and S26C), IPR014037 (Peptidase S26A), IPR011056 (Peptidase S24, S26A and S26B, C-terminal), IPR000223 (Peptidase S26A, signal peptidase I)
37	T26C5.4	T26C5.4	n/a	chrII 9,249,704	contains similarity to Encephalitozoon cuniculi SER/THR protein phosphatase 2-A (EC 3.1.3.16) (Serine/threoninesprotein phosphatase).; TR:Q8SS50
38	W04G3.7	W04G3.7	n/a	chrX 11,084,822	contains similarity to Interpro domain IPR001211 (Phospholipase A2)
39	pbo-4	K09C8.1	n/a	chrX 10,956,107	pbo-4 encodes a sodium/proton exchanger (also known as nhx-7), with a potential Ca[2+]/calmodulin binding domain in its C-terminal cytosolic region that could mediate calcium signaling; PBO-4 is expressed in the basolateral membrane of posterior intestinal cells; PBO-4 is required for normal posterior body muscle contraction (pBoc) during the defecation cycle; PBO-4 is thought to prevent intracellular acidification by catalysing the electroneutral exchange of extracellular sodium for an intracellular proton; specifically, PBO-4 may enable intercellular signals from intestinal cells (by secreting protons which then might activate PBO-5 in adjacent muscle cells).
40	col-162	Y2H9A.3	n/a	chrV 13,442,665	C. elegans COL-162 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (3)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
41	srw-73	T03E6.6	n/a	chrV 16,587,756	C. elegans SRW-73 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
42	T23D5.3	T23D5.3	n/a	chrV 15,733,239	contains similarity to Pfam domain PF03436 Domain of unknown function (DUF281) contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR001859 (Ribosomal protein P2), IPR005098 (Protein of unknown function DUF281)
43	srt-3	F47D2.3	n/a	chrV 4,259,059	C. elegans SRT-3 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
44	F35F10.14	F35F10.14	n/a	chrV 3,319,580
45	W04C9.6	W04C9.6	n/a	chrI 485,237	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
46	srh-77	DC2.6	n/a	chrV 224,988	C. elegans SRH-77 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	K09H11.5	K09H11.5	n/a	chrV 5,728,063
48	srv-11	H25K10.3	n/a	chrIV 16,220,615	C. elegans SRV-11 protein; contains similarity to Pfam domains PF01461 (7TM chemoreceptor) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002651 (Protein of unknown function DUF32)
49	R07E5.11	R07E5.11	n/a	chrIII 4,415,004	contains similarity to Salmonella typhimurium Putative surface-exposed virulence protein bigA precursor.; SW:BIGA_SALTY
50	F40G9.1	F40G9.1	n/a	chrIII 196,177	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)