UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T19H12.6	T19H12.6	0	chrV 4,877,093	contains similarity to Pfam domains PF04942 (CC domain) (2), PF01019 (Gamma-glutamyltranspeptidase) contains similarity to Interpro domains IPR007026 (Domian of unknown function, DUF-CC), IPR000101 (Gamma-glutamyltranspeptidase)
2	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
3	F55D12.2	F55D12.2	n/a	chrI 7,892,099	contains similarity to Interpro domains IPR002017 (Spectrin repeat), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal)
4	T01D1.4	T01D1.4	n/a	chrII 178,045	contains similarity to Pfam domain PF03079 ARD/ARD' family contains similarity to Interpro domains IPR011051 (Cupin, RmlC-type), IPR004313 (Acireductone dioxygenase, ARD), IPR014710 (RmlC-like jelly roll fold)
5	adr-2	T20H4.4	n/a	chrIII 7,231,956	adr-2 encodes an adenosine deaminase that acts on RNA (ADAR); ADARs are RNA-editing enzymes that deaminate adenosines to create inosines in double-stranded RNA (dsRNA); adr-2 is expressed ubiquitously in early embryos, as well as in the germline of early adults; ADR-2 is required for ADAR activity in vivo, and for normal chemotaxis.
6	crn-5	C14A4.5	n/a	chrII 10,593,065	C. elegans CRN-5 protein; contains similarity to Pfam domain PF01138 3' exoribonuclease family, domain 1 contains similarity to Interpro domain IPR001247 (Exoribonuclease, phosphorolytic domain 1)
7	ZK856.4	ZK856.4	n/a	chrV 10,183,835	contains similarity to Interpro domain IPR011001 (Saposin-like)
8	W02D7.6	W02D7.6	n/a	chrV 8,300,526	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
9	T22H2.4	T22H2.4	n/a	chrI 11,694,849	contains similarity to Pfam domain PF03860 Domain of Unknown Function (DUF326) contains similarity to Interpro domain IPR005560 (Protein of unknown function DUF326)
10	rap-1	C27B7.8	n/a	chrIV 8,917,869	rap-1 encodes a member of the Ras superfamily of small GTPases; the activated protein interacts with W05B10.4 and T14G10.2 in yeast two-hybrid assays and rap-1 is expressed in some neurons in the head and tail, the rectal epithelial cells, body muscle, hypodermis, and in the somatic cells of the gonad.
11	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
12	Y53C12A.3	Y53C12A.3	n/a	chrII 9,705,022	contains similarity to Pfam domains PF03942 (DTW domain) , PF04893 (Yip1 domain) contains similarity to Interpro domains IPR006977 (Yip1 domain), IPR005636 (DTW)
13	sdz-21	F54E7.5	n/a	chrIII 5,655,941	C. elegans SDZ-21 protein; contains similarity to Interpro domain IPR000480 (Glutelin)
14	C07B5.6	C07B5.6	n/a	chrX 9,520,189	contains similarity to Helicobacter pylori Hypothetical protein HP1327.; TR:O25885
15	ZK1098.3	ZK1098.3	n/a	chrIII 9,535,467	contains similarity to Pfam domain PF01612 3'-5' exonuclease contains similarity to Interpro domains IPR002562 (3'-5' exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
16	dhs-19	T11F9.11	n/a	chrV 11,489,664	dhs-19 encodes a short-chain dehydrogenase predicted to be mitochondrial.
17	F56D6.6	F56D6.6	n/a	chrIV 3,904,376
18	T05G5.4	T05G5.4	n/a	chrIII 9,749,322	contains similarity to Homo sapiens Trichohyalin; ENSEMBL:ENSP00000290632
19	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
20	srh-45	T03F7.2	n/a	chrV 11,304,292	C. elegans SRH-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002259 (Delayed-early response protein/equilibrative nucleoside transporter), IPR008075 (Lipocalin-1 receptor)
21	C29F7.6	C29F7.6	n/a	chrX 13,439,091	C29F7.6 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase; C29F7.6 contains a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); C29F7.6 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes; however, C29F7.6 has no obvious function in mass RNAi assays.
22	pfd-5	R151.9	n/a	chrIII 7,198,447	pfd-5 encodes a putative prefoldin 5 subunit, orthologous to human PFDN5 (OMIM:604899), that is required for normal microtubule growth, embryonic and larval viability, fertility, vulval development, and locomotion; PFD-5 is expressed in most, if not all, tissues; pfd-5(RNAi) animals show sterile progeny, larval arrest or lethality, uncoordination, and abnormal body shapes, and pfd-5(RNAi) embryos show a reduced microtubule growth rate.
23	Y62H9A.11	Y62H9A.11	n/a	chrX 11,906,196
24	F20B4.2	F20B4.2	n/a	chrX 17,704,274
25	C34D4.13	C34D4.13	n/a	chrIV 7,133,813
26	btb-13	ZC204.11	n/a	chrII 1,654,256	C. elegans BTB-13 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
27	mau-2	C09H6.3	n/a	chrI 8,127,936	mau-2 encodes an ortholog of budding yeast Scc4p, Drosophila CG4203, and human KIAA0892; MAU-2 is required (with PQN-85 and SCC-3) for normal mitotic chromosome segregation, and for cellular (e.g., neuronal) or axonal migration; MAU-2 is required for migration both embryonically and postembryonically, along both dorsoventral and longitudinal body axes; MAU-2 guides the axonal projection of AVM (and probably other neurons) by some cell-autonomous mechanism independent of SLT-1; MAU-2 is also required for normal larval development, locomotion, excretory canals and osmoregulation, phasmid morphology, and egg-laying; the primary sequences of MAU-2 and its Scc4-like orthologs are composed of tetratricopeptide repeats, and are highly divergent between yeast and metazoa; MAU-2 is expressed ubiquitously in embryos during late gastrulation, subsequently becoming restricted to neurons; mau-2 transcripts are abundant in oocytes, and maternal transcripts alone can support normal MAU-2 protein synthesis through the L3 larval stage (but not in L4 larvae or adults); MAU-2's N-terminal 371 residues of MAU-2 are its most conserved domain, and are sufficient to transgenically rescue mau-2 mutants; despite its behavioral phenotype, MAU-2 is thought to act early in development, since the uncoordinated phenotype of mau-2 mutants is maternal; while the uncoordinated phenotype of mau-2 mutants can be rescued either maternally or zygotically, the egg-laying phenotype of mau-2 mutants is purely zygotic; partially penetrant mau-2 dye-filling phenotypes occur on one side of the body, suggesting that MAU-2 acts on a whole side of an embryo at a time; while mau-2(RNAi) has no obvious early embryonic phenotype, joint mau-2/scc-3(RNAi) grossly deranges chromosomal segregation in early embryos, and mau-2(RNAi) enhances the lagging of anaphase chromosomes induced by pqn-85(RNAi).
28	F36D1.5	F36D1.5	n/a	chrI 11,266,244	contains similarity to Homo sapiens Melastatin 1; TR:O75560
29	ZK1225.1	ZK1225.1	n/a	chrI 13,206,699	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
30	T05C1.3	T05C1.3	n/a	chrII 4,488,577
31	str-161	T08B6.3	n/a	chrIV 4,903,231	C. elegans STR-161 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	D1005.2	D1005.2	n/a	chrX 1,460,943	contains similarity to Pfam domain PF01704 UTP--glucose-1-phosphate uridylyltransferase contains similarity to Interpro domains IPR016267 (UTP--glucose-1-phosphate uridylyltransferase, subgroup), IPR002618 (UTP--glucose-1-phosphate uridylyltransferase)
33	K10C2.2	K10C2.2	n/a	chrX 6,433,006	contains similarity to Interpro domain IPR000832 (GPCR, family 2, secretin-like)
34	C44C10.4	C44C10.4	n/a	chrX 11,694,526	contains similarity to Pfam domain PF02463 RecF/RecN/SMC N terminal domain contains similarity to Interpro domain IPR003395 (RecF/RecN/SMC protein, N-terminal)
35	srs-1	W03B1.4	n/a	chrIV 4,358,749	srs-1 encodes a predicted mitochondrial seryl-tRNA synthetase (SerRS), a class II aminoacyl-tRNA synthetase that catalyzes the attachment of serine to its cognate tRNA and is thus required for protein biosynthesis; in C. elegans, SRS-1 activity is required for normal postembryonic morphology and rates of growth.
36	atg-10	D2085.2	n/a	chrII 8,659,384	C. elegans ATG-10 protein; contains similarity to Pfam domain PF03987 Autophagocytosis associated protein, C-terminal domain contains similarity to Interpro domain IPR007135 (Autophagocytosis associated protein, C-terminal)
37	C44C10.5	C44C10.5	n/a	chrX 11,691,705	contains similarity to Homo sapiens Structural maintenance of chromosomes protein 1A; ENSEMBL:ENSP00000323421
38	bath-39	F25H9.4	n/a	chrV 13,460,604	C. elegans BATH-39 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
39	cal-3	M02B7.6	n/a	chrIV 3,832,350	cal-3 encodes a member of the calmodulin family.
40	fbxa-43	T20H9.2	n/a	chrIII 2,258,234	C. elegans FBXA-43 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
41	F54B11.10	F54B11.10	n/a	chrX 13,582,322	contains similarity to Conus arenatus Conotoxin scaffold VI/VII.; TR:Q9BP99
42	H37A05.2	H37A05.2	n/a	chrV 13,632,011	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
43	E02H9.6	E02H9.6	n/a	chrIII 2,439,204	contains similarity to Interpro domain IPR000694 (Proline-rich region)
44	F46F5.12	F46F5.12	n/a	chrII 807,746	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
45	C10A4.6	C10A4.6	n/a	chrX 7,391,386
46	srw-142	H05B21.3	n/a	chrV 2,957,658	C. elegans SRW-142 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
47	F42A6.6	F42A6.6	n/a	chrIV 3,336,420	contains similarity to Pfam domain PF05603 Protein of unknown function (DUF775) contains similarity to Interpro domain IPR008493 (Protein of unknown function DUF775)
48	end-3	F58E10.5	n/a	chrV 14,015,253	end-3 encodes a GATA zinc finger protein, paralogous to end-1, that helps specify mesoendodermal (as opposed to mesectodermal) lineages derived from the E blastomere.
49	rfc-2	F58F6.4	n/a	chrIV 1,350,136	rfc-2 encodes a member of the AAA family that are ATPases associated with DNA replication and has highest similarity to the mouse Replication factor C 40 kDa subunit, and affects embryonic viability, fertility, and locomotion in a large-scale RNAi screen.
50	T22G5.3	T22G5.3	n/a	chrV 13,882,397	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.