UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	myo-2	T18D3.4	0	chrX 12,471,624	myo-2 encodes a muscle-type specific myosin heavy chain isoform; myo-2 is expressed in pharyngeal muscle.
2	cyp-33C8	R08F11.3	n/a	chrV 3,802,105	C. elegans CYP-33C8 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
3	let-75	R06C7.10	0	chrI 7,263,197	let-75 encodes a pharynx-specific type II myosin heavy chain (MHC D); LET-75 is required for pharyngeal muscle contraction and thus for normal feeding behavior and post-embryonic development; in vitro, the LET-75 tail domain interacts with ITR-1, an IP3 receptor, and this interaction has been proposed to mediate, in vivo, increased pharnygeal pumping in response to food; LET-75 is expressed exclusively in pharyngeal muscle.
4	C50F4.2	C50F4.2	n/a	chrV 9,533,151	C50F4.2 encodes a putative 6-phosphofructokinase, paralogous to Y71H10A.1; C50F4.2 is required for fertility, full body size, and normally rapid growth in mass RNAi assays; C50F4.2 transcripts are enriched during spermatogenesis.
5	D1005.3	D1005.3	n/a	chrX 1,453,357	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
6	Y38H6C.15	Y38H6C.15	n/a	chrV 20,530,900	contains similarity to Interpro domain IPR006017 (Caldesmon)
7	T21B6.3	T21B6.3	n/a	chrX 10,946,988	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
8	fbxa-90	Y102A5C.19	n/a	chrV 16,967,704	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
9	F27E5.3	F27E5.3	n/a	chrII 10,142,746	contains similarity to Homo sapiens Isoform 1 of Cell division cycle 2-related protein kinase 7; ENSEMBL:ENSP00000300647
10	Y39A1A.14	Y39A1A.14	n/a	chrIII 10,649,949	contains similarity to Pfam domain PF03587 Nep1 ribosome biogenesis protein contains similarity to Interpro domain IPR005304 (Suppressor Mra1)
11	C25E10.5	C25E10.5	n/a	chrV 9,031,538	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
12	F13C5.5	F13C5.5	n/a	chrX 606,710
13	R102.1	R102.1	n/a	chrIV 10,686,816	contains similarity to Oryza sativa Similar to Arabidopsis thaliana chromosome 4.; TR:Q9LWR6
14	Y113G7B.14	Y113G7B.14	n/a	chrV 20,223,220	contains similarity to Pfam domains PF04851 (Type III restriction enzyme, res subunit) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR006935 (Restriction endonuclease, type I, R subunit/Type III, Res subunit), IPR000330 (SNF2-related), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal)
15	B0303.14	B0303.14	n/a	chrIII 8,714,993	contains similarity to Homo sapiens 33 kDa protein; VG:OTTHUMP00000025234
16	B0207.7	B0207.7	n/a	chrI 5,946,551	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
17	F55H12.2	F55H12.2	n/a	chrI 8,868,112	contains similarity to Interpro domain IPR000242 (Tyrosine specific protein phosphatase)
18	Y48A6B.8	Y48A6B.8	n/a	chrIII 11,028,225	contains similarity to Interpro domains IPR003547 (Serine/threonine protein kinase, yersinia), IPR013022 (Xylose isomerase-like, TIM barrel)
19	F37H8.3	F37H8.3	n/a	chrII 11,182,323	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR011945 (Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal), IPR006402 (HAD-superfamily hydrolase, subfamily IA, variant 3), IPR005834 (Haloacid dehalogenase-like hydrolase)
20	F35E8.1	F35E8.1	n/a	chrV 15,904,615	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
21	lgc-25	R03E1.3	n/a	chrX 14,160,175	C. elegans LGC-25 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR003567 (Cytochrome c-type biogenesis protein), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
22	B0272.4	B0272.4	n/a	chrX 9,429,267	contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
23	ZC247.1	ZC247.1	n/a	chrI 10,271,766	contains similarity to Drosophila melanogaster Flybase gene name is CG32377-PA;; FLYBASE:CG32377
24	fbxb-36	F07E5.6	n/a	chrII 2,061,815	C. elegans FBXB-36 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
25	C09G1.4	C09G1.4	n/a	chrX 15,992,503	contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
26	tag-141	C30H6.2	n/a	chrIV 17,365,684	tag-141/C30H6.2 encodes a putative zinc transporter orthologous to human SLC39A4 (OMIM:607059, mutated in acrodermatitis enteropathica).
27	K09A9.1	K09A9.1	n/a	chrX 15,609,812	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
28	tba-7	T28D6.2	n/a	chrIII 11,369,983	C. elegans TBA-7 protein; contains similarity to Pfam domains PF00091 (Tubulin/FtsZ family, GTPase domain) , PF03953 (Tubulin/FtsZ family, C-terminal domain) contains similarity to Interpro domains IPR002454 (Gamma tubulin), IPR002452 (Alpha tubulin), IPR002453 (Beta tubulin), IPR000217 (Tubulin), IPR003008 (Tubulin/FtsZ, GTPase), IPR004057 (Epsilon tubulin), IPR002967 (Delta tubulin), IPR000158 (Cell division protein FtsZ, N-terminal), IPR008280 (Tubulin/FtsZ, C-terminal)
29	ins-26	ZC334.1	n/a	chrI 14,037,463	ins-26 encodes an insulin-like peptide.
30	ari-1	C27A12.8	n/a	chrI 6,059,904	C. elegans ARI-1 protein; contains similarity to Pfam domain PF01485 IBR domain contains similarity to Interpro domains IPR009060 (UBA-like), IPR002867 (Zinc finger, C6HC-type)
31	fbxa-150	Y38H6C.11	n/a	chrV 20,518,929	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
32	R08C7.5	R08C7.5	n/a	chrIV 4,431,281	contains similarity to Pfam domain PF03941 Inner centromere protein, ARK binding region contains similarity to Interpro domains IPR005819 (Histone H5), IPR005635 (Inner centromere protein, ARK binding region)
33	ctl-1	Y54G11A.6	n/a	chrII 14,304,828	ctl-1 encodes one of three C. elegans catalases; CTL-1 exhibits catalase activity in vitro, and thus likely functions in vivo as an antioxidant enzyme that protects cells from reactive oxygen species; ctl-1 activity contributes to the extended lifespan seen in daf-2 mutant animals; in addition, ctl-1 expression is negatively regulated by DAF-2-mediated insulin signaling; as CTL-1 does not possess a C-terminal peroxisomal targeting signal (PTS), it is predicted to be a cytosolic catalase.
34	R09H10.2	R09H10.2	n/a	chrIV 10,606,027	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
35	daf-5	W01G7.1	n/a	chrII 14,035,373	daf-5 encodes a proline-rich protein, conserved in C. briggsae but not observed in non-nematode genomes, that promotes dauer formation in the group II branch of the dauer pathway, may regulate chemosensation via AWC neurons, and may regulate egg laying; daf-5 mutations suppress the dauer phenotype of group II Daf-c mutants; daf-5(e1385) partially suppresses dauer formation by aex-6(sa699) mutants at 26.8 degrees C.
36	mec-12	C44B11.3	n/a	chrIII 3,135,388	mec-12 encodes a novel C. elegans alpha-tubulin that is unique amongst C. elegans alpha tubulins in that it may be subject to post-translational acetylation; MEC-12 is required for normal mechanosensory response to gentle touch, and specifically for formation of the 15-protofilament microtubule bundle present in the touch receptor neurons; mec-12 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis; MEC-12 is highly expressed in the touch neurons as well as in several other neurons that do not contains the microfilament bundle, such as the ventral cord motorneurons.
37	srx-78	C01G10.3	n/a	chrV 15,096,226	C. elegans SRX-78 protein
38	myo-5	F58G4.1	0	chrV 8,113,539	C. elegans MYO-5 protein; contains similarity to Pfam domains PF01576 (Myosin tail) , PF00612 (IQ calmodulin-binding motif) , PF02736 (Myosin N-terminal SH3-like domain) , PF00063 (Myosin head (motor domain)) contains similarity to Interpro domains IPR010989 (t-SNARE), IPR002957 (Keratin, type I), IPR000533 (Tropomyosin), IPR009053 (Prefoldin), IPR004009 (Myosin, N-terminal, SH3-like), IPR002928 (Myosin tail), IPR001609 (Myosin head, motor region)
39	T15B12.2	T15B12.2	n/a	chrIII 5,300,917	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR000694 (Proline-rich region), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
40	wrt-3	F38E11.7	n/a	chrIV 9,476,571	wrt-3 encodes a hedgehog-like protein, with an N-terminal signal sequence, a Wart domain, and a region of low-complexity sequence; WRT-3 is expressed in the trinucleate pharyngeal gland cell g1 beginning at the three-fold stage of embryogenesis, in seam cells and hypodermis, and in single muscle cells and the distal tip cells of late stage larvae and adults; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-3 is required for normal growth to full size and locomotion; both of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
41	E02C12.11	E02C12.11	n/a	chrV 9,379,644	contains similarity to Pfam domain PF07914 Protein of unknown function (DUF1679) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species)
42	M117.4	M117.4	n/a	chrIV 11,832,142	contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003882 (Pistil-specific extensin-like protein)
43	ace-3	Y48B6A.8	n/a	chrII 14,207,809	ace-3 encodes one of four C. elegans acetylcholinesterases (AChE); ACE-3 represents ~5% of the total AChE activity in C. elegans and in vitro, hydrolyzes acetylthio-, butyrylthio-, and propionylthiocholine substrates with equal efficiency; although loss-of-function mutations in ace-3 result in no obvious defects, animals doubly mutant with ace-1 or ace-2 have slight defects in backward locomotion and animals triply mutant for ace-1, -2, and -3 arrest as unhatched, yet fully developed, embryos; ace-3 is the downstream gene in an operon with a fourth AChE-encoding gene, ace-4, and transcriptional reporter fusions with ace-4 upstream sequences direct expression in pharyngeal muscles pm3, 4, 5, and 7, the two CAN (canal associated neuron) cells, midbody dorsal body wall muscles in larvae, and several neurons in the head and anal ganglion
44	pgp-9	C47A10.1	n/a	chrV 17,760,286	pgp-9 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; PGP-9 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, and loss of pgp-9 activity via RNAi can result in embryonic lethality; pgp-9 promoter-gfp fusion proteins are expressed in the pharynx (first and second bulbs) and in the intestine.
45	ugt-43	F01D4.1	n/a	chrIV 10,466,113	C. elegans UGT-43 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
46	ZK180.2	ZK180.2	n/a	chrIV 4,504,345	contains similarity to Pfam domain PF01094 Receptor family ligand binding region contains similarity to Interpro domains IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR001828 (Extracellular ligand-binding receptor), IPR000923 (Blue (type 1) copper domain)
47	C36H8.1	C36H8.1	n/a	chrIV 12,743,886	contains similarity to Pfam domains PF03134 (TB2/DP1, HVA22 family) , PF00635 (MSP (Major sperm protein) domain) contains similarity to Interpro domains IPR008962 (PapD-like), IPR000694 (Proline-rich region), IPR000535 (Major sperm protein), IPR004345 (TB2/DP1 and HVA22 related protein)
48	C16D9.5	C16D9.5	n/a	chrV 8,244,484	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
49	Y54G11A.4	Y54G11A.4	n/a	chrII 14,294,300	contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR000023 (Phosphofructokinase)
50	C01B4.8	C01B4.8	n/a	chrV 2,491,606	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)