UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	pqn-66	T16A1.7	0	chrII 2,088,014	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
2	kin-14	F22D6.1	n/a	chrI 7,077,700	kin-14 encodes a member of the tyrosine-specific subfamily of kinases that contains an SH2 domain, and has with similarity to the human proto-oncogene tyrosine-protein kinase FER.
3	W07E11.1	W07E11.1	n/a	chrX 10,093,967	contains similarity to Pfam domains PF04898 (Glutamate synthase central domain) , PF01645 (Conserved region in glutamate synthase) , PF01266 (FAD dependent oxidoreductase) , PF00310 (Glutamine amidotransferases class-II) , PF07992 (Pyridine nucleotide-disulphide oxidoreductase) , PF00070 (Pyridine nucleotide-disulphide oxidoreductase) , PF01493 (GXGXG motif) contains similarity to Interpro domains IPR013027 (FAD-dependent pyridine nucleotide-disulphide oxidoreductase), IPR000583 (Glutamine amidotransferase, class-II), IPR013785 (Aldolase-type TIM barrel), IPR006076 (FAD dependent oxidoreductase), IPR006005 (Glutamate synthase, NADH/NADPH, small subunit 1), IPR000759 (Adrenodoxin reductase), IPR006982 (Glutamate synthase, central-N), IPR002932 (Glutamate synthase, central-C), IPR000103 (Pyridine nucleotide-disulphide oxidoreductase, class-II), IPR002489 (Glutamate synthase, alpha subunit, C-terminal), IPR012285 (Fumarate reductase, C-terminal), IPR001327 (Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region), IPR016040 (NAD(P)-binding), IPR012220 (Glutamate synthase, eukaryotic), IPR001100 (Pyridine nucleotide-disulphide oxidoreductase, class I)
4	nhr-215	T07C5.4	n/a	chrX 12,699,419	C. elegans NHR-215 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
5	srh-195	R52.7	n/a	chrII 2,115,763	C. elegans SRH-195 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	C04G6.2	C04G6.2	n/a	chrII 5,093,709	contains similarity to Pfam domain PF03380 Caenorhabditis protein of unknown function, DUF282 contains similarity to Interpro domain IPR005044 (Protein of unknown function DUF282, Caenorhabditis species)
7	ctg-1	H06O01.3	n/a	chrI 7,007,341	C. elegans CTG-1 protein; contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001071 (Cellular retinaldehyde binding/alpha-tocopherol transport), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR009038 (GOLD), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
8	C09B8.3	C09B8.3	n/a	chrX 6,009,216
9	cyp-33E2	F42A9.5	n/a	chrIV 8,613,501	C. elegans CYP-33E2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
10	M04F3.2	M04F3.2	n/a	chrI 4,766,635	contains similarity to Bradyrhizobium japonicum 30S ribosomal protein S6.; SW:Q89MW3
11	B0496.4	B0496.4	n/a	chrIV 7,428,290	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
12	srh-216	T20B3.5	n/a	chrV 16,826,380	C. elegans SRH-216 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	ced-11	ZK512.3	n/a	chrIII 9,122,267	The ced-11 gene encodes a predicted transmembrane ion channel related to the long transient receptor potential channel (LTRPC) subfamily of TRP channels found in Drosophila and mammals; CED-11 functions as a downstream effector in the programmed cell death pathway and may play a role in affecting the morphological changes seen in the nucleus, cytoplasm, and plasma membrane of apoptotic cells.
14	T19C3.4	T19C3.4	n/a	chrIII 619,226	contains similarity to Pfam domain PF03134 TB2/DP1, HVA22 family contains similarity to Interpro domain IPR004345 (TB2/DP1 and HVA22 related protein)
15	C16D9.4	C16D9.4	n/a	chrV 8,241,945	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domains IPR008068 (Cytochrome P450, E-class, group I, CYP2B-like), IPR012444 (Protein of unknown function DUF1647)
16	srg-25	T09D3.5	n/a	chrV 5,343,042	C. elegans SRG-25 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
17	C44B9.1	C44B9.1	n/a	chrIII 10,871,842	contains similarity to Interpro domains IPR008162 (Inorganic pyrophosphatase), IPR001220 (Legume lectin, beta domain)
18	C15C8.7	C15C8.7	n/a	chrV 12,744,584	contains similarity to Rhizobium loti Hypothetical protein mll2265.; TR:Q98IT0
19	srbc-75	M01B2.3	n/a	chrV 15,254,293	C. elegans SRBC-75 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
20	srd-59	E04F6.1	n/a	chrII 7,206,230	C. elegans SRD-59 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	srh-27	W05H5.4	n/a	chrII 12,449,129	C. elegans SRH-27 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
22	C04F1.1	C04F1.1	n/a	chrI 5,727,848	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
23	F29B9.11	F29B9.11	n/a	chrIV 4,659,939
24	asf-1	F10G7.3	n/a	chrII 4,702,628	C. elegans ASF-1 protein; contains similarity to Pfam domain PF04729 Anti-silencing protein, ASF1-like contains similarity to Interpro domains IPR006818 (Anti-silencing protein, ASF1-like), IPR017282 (Histone deposition protein Asf1)
25	K06G5.3	K06G5.3	n/a	chrX 14,221,334	contains similarity to Saccharomyces cerevisiae Required for invasion and pseudohyphae formation in response to nitrogen starvation; SGD:YIR019C
26	tag-51	K02F3.1	n/a	chrIII 855,363	C. elegans TAG-51 protein ;
27	gcy-8	C49H3.1	n/a	chrIV 7,930,918	gcy-8 encodes a receptor-type guanylyl cyclase that, along with gcy-18 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-8 functions redundantly with gcy-18 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; GCY-8 is expressed exclusively in the AFD thermosensory neurons where it localizes to sensory endings; GCY-8 expression in the AFD neurons requires activity of the TAX-2/4 cyclic nucleotide gated channel and the CMK-1 Ca2+/calmodulin-dependent protein kinase I, while maintenance of GCY-8 expression requires the OTD/OTX homeodomain protein TTX-1.
28	C28G1.2	C28G1.2	n/a	chrX 8,837,092	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
29	W03B1.2	W03B1.2	2e-98	chrIV 4,329,360	contains similarity to Interpro domains IPR002229 (Blood group Rhesus C/E and D polypeptide), IPR000769 (Regulatory protein Rop)
30	D1007.15	D1007.15	n/a	chrI 4,560,680	contains similarity to Mus musculus Uncharacterized protein KIAA0195.; SW:Q7TSH8
31	K03H4.1	K03H4.1	n/a	chrV 13,151,458	contains similarity to Helicobacter pylori Transposase OrfB.; TR:Q93C83
32	sre-12	T07H8.7	n/a	chrV 6,978,417	C. elegans SRE-12 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR001680 (WD40 repeat)
33	K05C4.10	K05C4.10	n/a	chrI 14,725,700	contains similarity to Enterococcus faecalis Hypothetical protein.; TR:Q836A3
34	spp-19	K04A8.9	n/a	chrV 6,559,648	C. elegans SPP-19 protein; contains similarity to Interpro domains IPR011001 (Saposin-like), IPR008139 (Saposin B)
35	srh-28	ZC404.5	n/a	chrV 6,774,975	C. elegans SRH-28 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	srg-61	C24B9.11	n/a	chrV 2,739,518	C. elegans SRG-61 protein; contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
37	cdr-3	C54D10.2	n/a	chrV 12,416,844	C. elegans CDR-3 protein; contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR010987 (Glutathione S-transferase, C-terminal-like)
38	F59F5.1	F59F5.1	n/a	chrX 10,530,779	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
39	bcc-1	M7.3	n/a	chrIV 11,089,293	bcc-1 encodes a homolog of Drosophila and vertebrate Bicaudal C (BICC) that contains KH RNA-binding domains, a serine-rich region, and a SAM (sterile alpha motif) domain; by homology, BCC-1 is predicted to function as a cytoplasmic RNA-binding protein that is required for translational regulation and/or mRNA stability during embryonic or germline development; however, as loss of bcc-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of BCC-1 in C. elegans development and/or behavior is not yet known.
40	lgc-23	C15A7.1	n/a	chrX 12,066,273	C. elegans LGC-23 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
41	Y38H6A.3	Y38H6A.3	n/a	chrV 20,342,053	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
42	C05C9.3	C05C9.3	n/a	chrX 11,148,023	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
43	lrx-1	T04H1.6	n/a	chrV 12,253,997	lrx-1 encodes a protein that contains four class A low-density lipoprotein receptor domains.
44	F36F12.7	F36F12.7	n/a	chrV 2,099,700
45	srw-58	H24D24.2	n/a	chrV 15,947,853	C. elegans SRW-58 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)
46	cyp-14A2	K09A11.3	n/a	chrX 13,268,561	C. elegans CYP-14A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
47	F20B4.3	F20B4.3	n/a	chrX 17,706,033
48	Y48B6A.1	Y48B6A.1	n/a	chrII 14,152,681	Y48B6A.1 encodes an ortholog of human BOP1 (OMIM:610596, overexpressed in colon cancer) and S. cerevisiae ERB1; Y48B6A.1 may suppress tumorous growth in the germline; like PRO-1, -2, and -3, Y48B6A.1 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline; however, BOP1 is also a phosphoprotein in mitotic spindles and required for normal chromosomal segregation, raising the possibility that Y48B6A.1 is multifunctional.
49	T07F10.6	T07F10.6	n/a	chrV 12,865,830	contains similarity to Pfam domain PF06879 Protein of unknown function (DUF1261) contains similarity to Interpro domain IPR009673 (Protein of unknown function DUF1261)
50	ZK185.2	ZK185.2	n/a	chrIV 4,539,155	ZK185.2 encodes an ortholog of human SLC41A1 (OMIM:610801) and bacterial MgtE; like its orthologs, ZK185.2 is predicted to transport Mg(2+) into cells; ZK185.2 is paralogous to K07H8.2 and ZK1053.6, and has no obvious function in mass RNAi assays.