UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T15D6.11	T15D6.11	0	chrI 12,397,457	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F13H10.5	F13H10.5	n/a	chrIV 10,992,558	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017850 (Alkaline-phosphatase-like, core domain)
4	ptr-11	F56C11.2	n/a	chrI 163,495	ptr-11 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-11 is required for normal growth to full size, locomotion, and vulval morphogenesis.
5	srt-22	ZK1037.3	n/a	chrV 15,315,273	C. elegans SRT-22 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
6	gfi-3	M163.4	n/a	chrX 14,482,535	gfi-3 is also known as apc-5, encoding a distant homolog of the human anaphase promoting complex subunit APC5, but is most closely related to its C. elegans paralog Y66D12A.17; gfi-3(RNAi) animals are generally unable to progress through meiotic divisions; initially they produce reduced numbers of viable embryos mixed with inviable embryos, but then show severe germline maintenance defects and become sterile.
7	F22G12.4	F22G12.4	n/a	chrI 13,157,287	contains similarity to Pfam domains PF01363 (FYVE zinc finger) , PF00023 (Ankyrin repeat) (17)contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002110 (Ankyrin), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
8	sri-27	ZK697.4	n/a	chrV 1,726,643	C. elegans SRI-27 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	C06G1.5	C06G1.5	n/a	chrX 16,640,570	contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
10	T07G12.3	T07G12.3	n/a	chrIV 10,535,145	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
11	Y51B9A.5	Y51B9A.5	n/a	chrII 9,404,343	contains similarity to Mus musculus Laminin gamma-1 chain precursor (Laminin B2 chain).; SW:LMG1_MOUSE
12	C18B10.6	C18B10.6	n/a	chrV 7,480,150	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
13	C15H9.3	C15H9.3	n/a	chrX 6,116,887	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
14	srx-108	F40H7.2	n/a	chrII 3,706,336	C. elegans SRX-108 protein ;
15	T07C4.10	T07C4.10	n/a	chrIII 10,323,248	contains similarity to Interpro domains IPR002957 (Keratin, type I), IPR000533 (Tropomyosin), IPR009053 (Prefoldin)
16	F56F10.4	F56F10.4	n/a	chrX 867,910	contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR000664 (Lethal(2) giant larvae protein)
17	K09H11.1	K09H11.1	n/a	chrV 5,749,898	contains similarity to Pfam domains PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF01636 (Phosphotransferase enzyme family) , PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR011945 (Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal), IPR005833 (Haloacid dehydrogenase/epoxide hydrolase), IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR011009 (Protein kinase-like), IPR006402 (HAD-superfamily hydrolase, subfamily IA, variant 3), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR000169 (Peptidase, cysteine peptidase active site), IPR005834 (Haloacid dehalogenase-like hydrolase), IPR008266 (Tyrosine protein kinase, active site), IPR002575 (Aminoglycoside phosphotransferase)
18	gpdh-1	F47G4.3	n/a	chrI 14,077,014	gpdh-1 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-1 activity via large-scale RNAi screens results in no obvious defects, gpdh-1 mRNA expression is upregulated in response to hypertonicity, suggesting that GPDH-1 does play a role in osmotic stress adaptation in C. elegans.
19	F41A4.1	F41A4.1	n/a	chrIV 686,411	contains similarity to Pfam domain PF00024 PAN domain contains similarity to Interpro domains IPR000177 (Apple), IPR003609 (Apple-like), IPR003014 (N/apple PAN), IPR001507 (Endoglin/CD105 antigen)
20	K09F6.8	K09F6.8	n/a	chrII 2,295,399
21	K08D10.5	K08D10.5	n/a	chrIV 4,168,957	contains similarity to Rhodopirellula baltica DNA-binding protein SMUBP-2.; TR:Q7UWP1
22	his-43	F08G2.2	n/a	chrII 13,827,426	his-43 encodes an H2A histone.
23	C46H3.1	C46H3.1	n/a	chrX 1,210,043
24	nhr-267	H22D14.1	n/a	chrIV 9,285,626	C. elegans NHR-267 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
25	C35A5.5	C35A5.5	n/a	chrV 10,506,811	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
26	F55G1.13	F55G1.13	n/a	chrIV 7,496,503	F55G1.13 encodes a protein that contains EGF-like repeats that are most closely related to those of Notch family members.
27	let-711	F57B9.2	n/a	chrIII 6,952,757	let-711 encodes the C. elegans ortholog of NOT1, the conserved core component of the multisubunit CCR4/NOT complex that plays a role in regulation of gene expression via various processes including transcriptional control, mRNA deadenylation, and protein ubiquitination; in C. elegans, let-711 activity is essential for embryonic and larval development and in particular, for proper spindle positioning, microtubule length, and centrosome morphology in early embryos; in addition, let-711 is essential for normal germline development and levels of fertility; in embryos, let-711 mutations can suppress the short microtubule phenotype produced by mutations in zyg-9, which encodes the C. elegans XMAP125 homolog, and centrosomoal ZYG-9 levels are increased in let-711 mutants, suggesting that let-711 functions, in part, by negatively regulating ZYG-9 levels or localization; in situ hybridization studies indicate that let-711 mRNA is broadly expressed in the gonad and that its gonadal expression is negatively regulated by lin-35/Rb.
28	C49A9.3	C49A9.3	n/a	chrIV 6,223,512	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domains IPR000711 (ATPase, F1 complex, OSCP/delta subunit), IPR004987 (Protein of unknown function DUF272)
29	T20H9.6	T20H9.6	n/a	chrIII 2,247,987	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
30	K09F6.5	K09F6.5	n/a	chrII 2,272,724	contains similarity to Interpro domain IPR000358 (Ribonucleotide reductase)
31	C42D4.2	C42D4.2	n/a	chrIV 7,181,781	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
32	evl-14	H38K22.1	n/a	chrIII 4,308,081	evl-14 encodes a homolog of the yeast sister cohesion protein Pds5p that functions during both mitosis and meiosis and is implicated in the maintenance of sister chromatid cohesion in late prophase, and affects vulval morphology, meiotic germline development, embryonic and larval viability, fertility, and cell divisions in the germ line as well as in vulval and somatic gonad lineages; some of the defects, such as somatic gonad defects, are due at least partially to cell division defects.
33	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
34	K09F6.2	K09F6.2	n/a	chrII 2,268,709	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
35	K07E3.2	K07E3.2	n/a	chrX 8,105,875
36	M88.4	M88.4	n/a	chrIII 4,550,251	contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR006020 (Phosphotyrosine interaction region)
37	hil-8	T05E8.2	n/a	chrI 5,467,787	C. elegans HIL-8 protein; contains similarity to Interpro domain IPR005818 (Histone H1/H5)
38	apt-9	W04G3.4	n/a	chrX 11,070,152	apt-9 gene encodes an ortholog of GGA (Golgi-localizing, gamma-adaptin ear homology, ARF-binding protein), which contains a domain paralogous to the gamma-adaptin subunits of adaptor protein complexes; based on structural similarity, APT-9 may beinvolved in the formation of intracellular transport vesicles.
39	C33A12.1	C33A12.1	n/a	chrIV 9,524,313	C33A12.1 encodes the C. elegans ortholog of the NDUFA5/B13 subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I).
40	C49C3.5	C49C3.5	n/a	chrIV 17,329,906	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
41	nph-1	M28.7	n/a	chrII 10,650,519	nph-1 encodes a novel, SH3 domain-containing protein that is orthologous to mammalian nephrocystin-1.
42	C27H6.3	C27H6.3	n/a	chrV 9,981,996	contains similarity to Homo sapiens Acidic (Leucine-rich) nuclear phosphoprotein 32 family, member E; ENSEMBL:ENSP00000358111
43	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
44	pps-1	T14G10.1	n/a	chrIV 10,163,166	pps-1 is orthologous to human PAPSS1 (OMIM:603262) and human PAPSS2 (OMIM:603005, mutated in spondyloepimetaphyseal dysplasia).
45	F56A12.2	F56A12.2	n/a	chrV 14,377,560	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
46	ZC250.2	ZC250.2	n/a	chrV 5,793,898	contains similarity to Pfam domain PF00535 Glycosyl transferase family 2 contains similarity to Interpro domain IPR001173 (Glycosyl transferase, family 2)
47	R05H11.1	R05H11.1	n/a	chrIII 6,796,617	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
48	str-7	F22B8.5	n/a	chrV 16,098,738	C. elegans STR-7 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	sri-17	F15H9.3	n/a	chrI 12,145,482	C. elegans SRI-17 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	C31E10.7	C31E10.7	n/a	chrX 14,002,346	C31E10.7 is orthologous to the human gene UNKNOWN (PROTEIN FOR MGC:10230) (CYB5; OMIM:250790), which when mutated leads to disease.