UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srv-32	T13A10.12	0	chrIV 6,281,179	C. elegans SRV-32 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
2	nhr-55	T01G6.7	n/a	chrV 479,428	nhr-55 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
3	srh-20	C02E7.3	n/a	chrV 4,925,540	C. elegans SRH-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
4	T26F2.1	T26F2.1	n/a	chrV 13,975,534	contains similarity to Pfam domain PF00182 Chitinase class I contains similarity to Interpro domain IPR000726 (Glycoside hydrolase, family 19, catalytic)
5	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
6	nekl-2	ZC581.1	n/a	chrI 6,664,152	nekl-2 encodes a putative serine/threonine protein kinase orthologous to Aspergillus nidulans nimA and human NEK8 (OMIM:609799), and paralogous to C. elegans D1044.3, D1044.8, F19H6.1, and Y39G10AR.3; nekl-2 interacts with two or more components of the EGF/RAS signalling pathway, and is required for such signalling in vulval development.
7	F27D9.7	F27D9.7	n/a	chrX 7,667,592	contains similarity to Pfam domain PF01421 Reprolysin (M12B) family zinc metalloprotease contains similarity to Interpro domain IPR001590 (Peptidase M12B, ADAM/reprolysin)
8	ZC190.2	ZC190.2	n/a	chrV 8,682,033	contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
9	T10B11.5	T10B11.5	n/a	chrI 6,941,098	contains similarity to Pfam domain PF05705 Eukaryotic protein of unknown function (DUF829) contains similarity to Interpro domain IPR008547 (Protein of unknown function DUF829, eukaryotic)
10	F39B2.7	F39B2.7	n/a	chrI 14,772,840	contains similarity to Pfam domain PF01926 GTPase of unknown function contains similarity to Interpro domains IPR005289 (GTP-binding), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR002917 (GTP-binding protein, HSR1-related), IPR003593 (AAA+ ATPase, core), IPR006073 (GTP1/OBG), IPR004520 (tRNA modification GTPase TrmE)
11	Y51B9A.4	Y51B9A.4	n/a	chrII 9,408,334	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
12	C31H5.1	C31H5.1	n/a	chrI 9,028,536	contains similarity to Pfam domain PF06342 Alpha/beta hydrolase of unknown function (DUF1057) contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR010463 (Protein of unknown function DUF1057, lipase putative)
13	nhr-270	R13D11.8	n/a	chrV 803,647	C. elegans NHR-270 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
14	gcy-14	ZC412.2	n/a	chrV 14,865,514	gcy-14 encodes a predicted transmembrane guanylyl cyclase; the precise role of GCY-14 in C. elegans development and/or behavior is not yet known; however, by sequence similarity GCY-14 can be predicted to function in chemosensory signal transduction.
15	srw-107	R11G11.13	n/a	chrV 520,735	C. elegans SRW-107 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
16	F01G10.5	F01G10.5	n/a	chrIV 10,229,551	contains similarity to Interpro domain IPR011072 (HR1 rho-binding repeat)
17	T10B11.4	T10B11.4	n/a	chrI 6,938,560
18	C30E1.7	C30E1.7	n/a	chrX 16,915,205
19	T09F5.1	T09F5.1	n/a	chrV 15,149,875	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
20	F26D11.4	F26D11.4	n/a	chrV 7,947,903
21	pqn-29	F10F2.9	n/a	chrIII 4,645,137	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
22	ers-1	Y41E3.4	n/a	chrIV 15,010,805	ers-1 encodes a glutaminyl (Q) tRNA synthetase that affects growth and embryonic and larval viability in large-scale RNAi screens; it is predicted to be mitochondrial.
23	T06C12.11	T06C12.11	n/a	chrV 15,893,552	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	ceh-8	ZK265.4	n/a	chrI 8,248,368	ceh-8 encodes a paired-like homeodomain protein of the Q50 class orthologous to the Rx homeobox protein of humans (RAX; OMIM:601881) and Drosophila (CG10052-PA); CEH-8 and RX belong to one of at least 18 distinct families of paired-like homeodomain proteins, including 12 families in the Q50 class.
25	srsx-21	R07B5.5	n/a	chrV 9,838,755	C. elegans SRSX-21 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
26	C33F10.11	C33F10.11	n/a	chrII 4,834,476
27	F54H12.4	F54H12.4	n/a	chrIII 7,962,097
28	F35C8.8	F35C8.8	n/a	chrX 5,373,263
29	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
30	srbc-45	ZC455.11	n/a	chrV 12,804,041	C. elegans SRBC-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
31	C18B2.4	C18B2.4	n/a	chrX 3,605,110	contains similarity to Pfam domain PF02893 GRAM domain contains similarity to Interpro domains IPR001419 (HMW glutenin), IPR004182 (GRAM)
32	F36G9.13	F36G9.13	n/a	chrV 15,984,973	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003125 (Protein of unknown function WSN)
33	nhr-140	C33G8.9	n/a	chrV 6,988,762	C. elegans NHR-140 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
34	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
35	tag-182	C16A3.7	n/a	chrIII 6,377,219	C. elegans TAG-182 protein; contains similarity to Pfam domains PF01422 (NF-X1 type zinc finger) (9), PF01424 (R3H domain) contains similarity to Interpro domains IPR000967 (Zinc finger, NF-X1-type), IPR001841 (Zinc finger, RING-type), IPR001374 (Single-stranded nucleic acid binding R3H), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
36	pgp-11	DH11.3	n/a	chrII 7,999,300	pgp-11 encodes an ATP-binding protein that is a member of the P-glycoprotein subclass of the ATP-binding cassette (ABC) transporter superfamily; pgp-11 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of pgp-11 activity via large-scale RNAi screens does not result in any obvious defects, the precise role of pgp-11 in C. elegans development and/or behavior is not yet known; pgp-11 promoter-gfp fusion proteins are expressed in the excretory cell and in the intestine.
37	epac-1	T20G5.5	n/a	chrIII 10,191,417	C. elegans EPAC-1 protein; contains similarity to Pfam domains PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin) , PF00027 (Cyclic nucleotide-binding domain) (2), PF00617 (RasGEF domain) , PF00618 (Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif) contains similarity to Interpro domains IPR008937 (Ras guanine nucleotide exchange factor), IPR011051 (Cupin, RmlC-type), IPR001895 (Guanine-nucleotide dissociation stimulator CDC25), IPR011991 (Winged helix repressor DNA-binding), IPR000595 (Cyclic nucleotide-binding), IPR002373 (cAMP/cGMP-dependent protein kinase), IPR014710 (RmlC-like jelly roll fold), IPR000651 (Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal), IPR000591 (Pleckstrin/ G-protein, interacting region)
38	C30G12.2	C30G12.2	n/a	chrII 7,290,986	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
39	T01G9.3	T01G9.3	n/a	chrI 8,283,218	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) (9), PF01463 (Leucine rich repeat C-terminal domain) contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
40	gly-16	T15D6.2	n/a	chrI 12,380,173	gly-16 encodes a protein similar to 2/I N-acetylglucosaminyltransferase; gly-16 is expressed in the seam cells during embryonic stages.
41	egl-2	F16B3.1	n/a	chrV 1,294,353	egl-2 encodes a voltage-gated potassium channel that affects egg laying, muscle activation, defecation, mechanosensation, and chemosensation; expressed in the intestinal muscle, AFD, ALN, AQR, ASE, AWC, BAG, IL2, PLN, PQR, and URX neurons as well as a subset of sensory neurons in the male tail.
42	nhl-1	F54G8.4	n/a	chrIII 9,150,557	The nhl-1 gene encodes an RBCC protein, orthologous to the mammalian protein BERP; its C. elegans paralogs include ncl-1 and lin-41.
43	T04B2.5	T04B2.5	n/a	chrIV 10,057,860	contains similarity to Pfam domain PF01734 Patatin-like phospholipase contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR002641 (Patatin)
44	vps-26	T20D3.7	n/a	chrIV 9,340,583	C. elegans VPS-26 protein; contains similarity to Pfam domain PF03643 Vacuolar protein sorting-associated protein 26 contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR005377 (Vacuolar protein sorting-associated protein 26)
45	ZC412.4	ZC412.4	n/a	chrV 14,869,132	contains similarity to Brugia malayi Major allergen.; TR:Q9BJC9
46	ugt-32	F47C10.6	n/a	chrV 3,842,918	C. elegans UGT-32 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
47	T10H10.3	T10H10.3	n/a	chrX 2,285,608	contains similarity to Pfam domain PF00397 WW domain contains similarity to Interpro domains IPR011524 (SARAH), IPR001202 (WW/Rsp5/WWP)
48	C31E10.8	C31E10.8	n/a	chrX 14,007,275	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domains IPR000195 (RabGAP/TBC), IPR011046 (WD40 repeat-like), IPR002011 (Receptor tyrosine kinase, class II, conserved site)
49	F54F2.9	F54F2.9	n/a	chrIII 8,826,142	contains similarity to Pfam domains PF00249 (Myb-like DNA-binding domain) , PF00226 (DnaJ domain) contains similarity to Interpro domains IPR015609 (Molecular chaperone, heat shock protein, Hsp40, DnaJ), IPR001005 (SANT, DNA-binding), IPR003095 (Heat shock protein DnaJ), IPR001623 (Heat shock protein DnaJ, N-terminal), IPR014778 (Myb, DNA-binding), IPR009057 (Homeodomain-like)
50	mkk-4	F42G10.2	n/a	chrX 10,028,926	mkk-4 encodes a MAP (mitogen-activated protein) kinase kinase that is a member of the MKK4 family of MAPKK's; MKK-4 activity is required in presynaptic neurons, in a dose-dependent manner, for normal presynaptic development and morphology; in regulating presynaptic organization, MKK-4 acts upstream of PMK-3/MAPK and downstream of DLK-1/MAPKKK, whose levels are negatively regulated by the RPM-1 ubiquitin ligase; a functional MKK-4::GFP fusion protein is expressed in the cytoplasm of many neurons as well as in other cell types, including the pharyngeal muscles.