UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T13A10.1	T13A10.1	4e-45	chrIV 6,276,666	contains similarity to Danio rerio Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-).; SW:Q8JFV8
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	spe-38	Y52B11A.1	n/a	chrI 10,965,401	C. elegans SPE-38 protein ;
4	fax-1	F56E3.4	n/a	chrX 3,198,294	fax-1 encodes a conserved nuclear receptor that contains two C4-type zinc fingers and is orthologous to the vertebrate photoreceptor-specific nuclear receptor PNR (OMIM:604485, mutated in enhanced S-cone syndrome and retinitis pigmentosa); fax-1 is required for normal locomotion and neuron fate specification, including specification of the AVA, AVE, and AVK interneurons and proper axon pathfinding of the AVK, HSNL, and PVQL axons; expression of reporter gene fusions in fax-1 mutants suggests that fax-1 functions by regulating expression of a number of downstream targets, including nmr-1 and nmr-2, opt-3, flp-1, and ncs-1; in some neurons, fax-1 regulates expression combinatorially with unc-42, which encodes a paired-like homeodomain protein that additionally, regulates fax-1 expression in AVK neurons; FAX-1 is expressed in the nuclei of 18 neurons, including the AVK, AVA, AVB, and AVE interneurons, beginning at mid-embryogenesis and continuing through larval and adult stages; FAX-1 is also seen in two non-neuronal cell types: the distal tip cells (DTCs), from L2 to L4 larval stages, and two pairs of vulval cells in L4 animals.
5	srw-7	R08F11.5	n/a	chrV 3,806,992	C. elegans SRW-7 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
6	W04C9.5	W04C9.5	n/a	chrI 464,897	contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
7	F02E11.3	F02E11.3	n/a	chrII 3,273,416	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
8	T13C2.2	T13C2.2	n/a	chrII 6,795,686
9	F53H4.4	F53H4.4	n/a	chrX 15,867,475	contains similarity to Salmonella typhi Hypothetical protein STY0658.; TR:Q8Z8J9
10	cof-2	C48E7.5	n/a	chrI 6,251,698	cof-2 encodes a homolog of human GLC1A, which when mutated leads to glaucome primary open angle (OMIM:137750)
11	C34E7.3	C34E7.3	n/a	chrX 12,931,101	contains similarity to Plasmodium falciparum Ribonuclease, putative.; TR:Q8ICL5
12	R09H10.1	R09H10.1	n/a	chrIV 10,601,257	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
13	srt-8	C50H11.2	n/a	chrV 3,087,272	C. elegans SRT-8 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
14	sri-47	F22E5.4	n/a	chrII 2,657,583	C. elegans SRI-47 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
16	F13A2.3	F13A2.3	n/a	chrV 4,394,967
17	qui-1	Y45F10B.10	n/a	chrIV 13,568,114	The qui-1 gene encodes a protein of unknown function that contains several WD-40 domains.
18	T27A8.5	T27A8.5	n/a	chrX 16,065,286	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
19	lgc-54	T15B7.16	n/a	chrV 6,841,721	C. elegans LGC-54 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
20	sph-1	F42G8.11	n/a	chrIV 8,132,914	sph-1 encodes a member of the synaptophysin/synaptoporin family that contains a MARVEL domain, a membrane-associating domain found in lipid-associating proteins, and contains a transmembrane domain.
21	C34E11.2	C34E11.2	n/a	chrX 11,808,336	contains similarity to Pfam domain PF03166 MH2 domain contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR000694 (Proline-rich region), IPR001132 (SMAD domain, Dwarfin-type), IPR017855 (SMAD domain-like)
22	clec-192	Y116A8A.1	n/a	chrIV 16,803,039	C. elegans CLEC-192 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	R07A4.3	R07A4.3	n/a	chrX 10,756,469	contains similarity to Interpro domain IPR000694 (Proline-rich region)
24	D1044.1	D1044.1	n/a	chrIII 5,545,251	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
25	R07B1.6	R07B1.6	n/a	chrX 9,867,228	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
26	ZK1225.2	ZK1225.2	n/a	chrI 13,209,439	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
27	R02F11.2	R02F11.2	n/a	chrV 4,795,145
28	fbxa-148	Y102A5C.9	n/a	chrV 16,939,509	C. elegans FBXA-148 protein; contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
29	sre-43	W07G1.6	n/a	chrII 13,967,710	C. elegans SRE-43 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
30	clec-229	H02K04.1	n/a	chrV 15,340,763	C. elegans CLEC-229 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR001202 (WW/Rsp5/WWP)
31	fbxa-130	F42A6.8	n/a	chrIV 3,340,450	C. elegans FBXA-130 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
32	C18D11.1	C18D11.1	n/a	chrIII 11,818,072	contains similarity to Sporobolus stapfianus Hypothetical protein.; TR:O04820
33	srxa-15	Y44A6B.2	n/a	chrV 20,638,710	C. elegans SRXA-15 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
34	nep-2	T05A8.4	n/a	chrII 2,721,578	T05A8.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while T05A8.4 is an ortholog of mammalian neutral endopeptidase (NEP), expressed on the brush-border membranes of kidney; more generally, T05A8.4 falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes).
35	Y37H9A.3	Y37H9A.3	n/a	chrI 13,785,519	contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000694 (Proline-rich region), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR006608 (Protein of unknown function DM14), IPR000008 (C2 calcium-dependent membrane targeting)
36	F49C12.1	F49C12.1	n/a	chrIV 9,295,603	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
37	Y37D8A.22	Y37D8A.22	n/a	chrIII 12,937,773	contains similarity to Danio rerio Transmembrane protein 49.; SW:Q6NYY9
38	glb-11	C36E8.2	n/a	chrIII 3,990,752	glb-11 encodes a globin; glb-11 transcription is higher in L3 and dauers than in young adults; glb-11 has no obvious function in mass RNAi assays; glb-11 expression is induced by anoxia in a HIF-1 dependent manner, although it is also paradoxically upregulated in a hif-1 mutant background.
39	Y40H7A.2	Y40H7A.2	n/a	chrIV 15,156,851	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
40	D1081.4	D1081.4	n/a	chrI 8,475,188	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
41	lact-3	M28.6	n/a	chrII 10,654,998	lact-3 encodes a beta-lactamase domain-containing protein that contains a predicted signal sequence; loss of lact-3 activity via RNAi has been reported to result in reduced fat content.
42	lon-2	C39E6.1	n/a	chrX 4,743,993	lon-2 encodes a member of the glypican family of heparan sulfate proteoglycans; during development, lon-2 activity is required in the hypodermis for negative regulation of the DBL-1/BMP signaling pathway that regulates body length; genetic analyses indicate that lon-2 functions upstream of dbl-1, and in vitro studies show that LON-2 can bind mammalian BMP2, suggesting that LON-2 may directly interact with DBL-1 to negatively regulate DBL-1/BMP signaling; in addition to expression in hypodermis, LON-2 is expressed strongly in the intestine, particularly the anterior and posterior cells; LON-2 localizes to the cell surface.
43	elp-1	F38A6.2	n/a	chrV 20,762,946	elp-1 encodes a WD repeat-containing protein that is the sole C. elegans EMAP (echinoderm microtubule-associated protein) homolog; ELP-1 binds microtubules in vitro, but as loss of ELP-1 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of ELP-1 in C. elegans development and/or behavior is not yet known; ELP-1 is expressed in many tissues, including body wall muscle, male-specific sex muscles, the vulva, spermatheca, sensory neurons, and intestinal cells.
44	srh-275	C03G6.7	n/a	chrV 7,353,665	C. elegans SRH-275 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	srb-5	C27D6.6	n/a	chrII 5,162,671	C. elegans SRB-5 protein; contains similarity to Pfam domain PF02175 C.elegans integral membrane protein Srb contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
46	C31H2.4	C31H2.4	n/a	chrX 5,157,381	C31H2.4 encodes a possible 4-hydroxyphenylpyruvate dioxygenase, orthologous to human HPDL/GLOXD1, and paralogous to HPD-1 and human HPD (OMIM:609695, mutated in tyrosinemia type III); C31H2.4 has no obvious function in mass RNAi experiments.
47	snt-6	C08G5.4	n/a	chrII 747,906	C. elegans SNT-6 protein; contains similarity to Pfam domain PF00168 C2 domain contains similarity to Interpro domains IPR001565 (Synaptotagmin), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR000008 (C2 calcium-dependent membrane targeting)
48	C15C8.5	C15C8.5	n/a	chrV 12,749,106	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
49	C24A3.4	C24A3.4	n/a	chrX 8,993,472	contains similarity to Pfam domain PF02515 CoA-transferase family III contains similarity to Interpro domains IPR016160 (Aldehyde dehydrogenase, conserved site), IPR003673 (CoA-transferase family III)
50	W04G5.8	W04G5.8	n/a	chrI 11,650,893	contains similarity to Pfam domain PF05075 Protein of unknown function (DUF684) contains similarity to Interpro domain IPR007767 (Protein of unknown function DUF684)