UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T12G3.6	T12G3.6	3e-96	chrIV 12,030,485	contains similarity to Helicobacter pylori Hypothetical protein HP1128.; TR:O25753
2	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
3	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
4	F08F3.6	F08F3.6	n/a	chrV 5,419,025	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
5	R04D3.4	R04D3.4	n/a	chrX 13,288,277	contains similarity to Rattus norvegicus Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkessdisease-associated protein homolog).; SW:AT7A_RAT
6	cdc-25.3	ZK637.11	n/a	chrIII 8,917,082	cdc-25.3 encodes a tyrosine phosphatase that is a member of the cell division cycle 25 (CDC25) family of cell cycle regulators that includes Schizosaccharomyces pombe CDC25 and Drosophila string; cdc-25.3 is one of four cdc-25 genes in C. elegans and while it is known to be expressed in hermaphrodites, the precise function of cdc-25.3 is not yet clear; cdc-25.3 may function redundantly with cdc-25.2 during embryonic development and redundantly with cdc-25.1, cdc-25.2, and emb-29 during meiosis.
7	F14D7.2	F14D7.2	n/a	chrV 14,292,817	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
8	C31G12.1	C31G12.1	n/a	chrV 18,180,590	contains similarity to Kaposi's sarcoma-associated herpesvirus K1 glycoprotein (Fragment).; TR:Q9WHA1
9	rgs-8.1	F52D2.2	n/a	chrX 1,953,014	C. elegans RGS-8.1 protein; contains similarity to Interpro domains IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)
10	Y6G8.3	Y6G8.3	n/a	chrV 17,602,355	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR001781 (Zinc finger, LIM-type), IPR007087 (Zinc finger, C2H2-type)
11	H04M03.3	H04M03.3	n/a	chrIV 5,892,434	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
12	T21C9.13	T21C9.13	n/a	chrV 10,597,963	contains similarity to Fusobacterium nucleatum Branched chain amino acid transport system II carrier protein.; TR:Q8REN9
13	R04D3.2	R04D3.2	n/a	chrX 13,285,808	contains similarity to Plasmodium falciparum Putative uncharacterized protein PFD0207c.; TR:Q8I1Y6
14	F43G6.10	F43G6.10	n/a	chrII 11,809,738	contains similarity to Interpro domain IPR000694 (Proline-rich region)
15	mom-2	F38E1.7	n/a	chrV 8,357,065	mom-2 encodes a member of the Wnt family of secreted signaling glycoproteins that is required for induction of endodermal (gut) tissue in the 4-cell stage embryo; MOM-2, required in the inducing blastomere (P2) at the 4-cell stage, may be the ligand for MOM-5, a Frizzled homolog, thought to act in the receiving blastomere (EMS); MOM-2 genetically interacts in the same pathway as KIN-19, but parallel to APR-1; MOM-2 also may be a ligand for LIN-18, a Ryk homolog.
16	C17E7.4	C17E7.4	n/a	chrV 3,893,699
17	F14H3.6	F14H3.6	n/a	chrV 16,058,082	contains similarity to Homo sapiens Similar to golgi SNAP receptor complex member 2; ENSEMBL:ENSP00000318814
18	F53F8.3	F53F8.3	n/a	chrV 20,684,555	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
19	kbp-1	R13F6.1	n/a	chrIII 6,869,906	C. elegans KBP-1 protein ;
20	sea-1	F19B10.9	n/a	chrII 3,672,747	sea-1 encodes a T-box transcription factor; during development, sea-1 functions, zygotically and in a dose-dependent manner, as an autosomal element of the X:A (X chromosome:autosome) ratio that determines C. elegans sex; in opposition to the X signal elements, SEA-1 positively regulates transcription of xol-1, the master sex-determination switch gene that is essential for male development and for setting the proper activity level of the dosage compensation complex; consistent with its role as a regulator of sex determination, SEA-1 is expressed in nuclei of early embryos from approximately the 20- to 100-cell stage of embryogenesis.
21	nos-2	ZK1127.1	n/a	chrII 7,066,218	nos-2 encodes one of three genes in C. elegans that contains a putative zinc-binding domain similar to the one found in Drosophila nanos; nos-2 affects incorporation of primordial germ cells into the somatic gonad, is required redundantly with nos-1 to prevent primordial germ cells from dividing in starved animals and to maintain germ cell viability during larval development in hermaphrodites and in males, and also functions together with nos-1 and nos-3 in the hermaphrodite switch from spermatogenesis to oogenesis; nos-2 is expressed in the primordial germ cells around the time of gastrulation from a maternal RNA associated with P granules, and it is expressed coordinately with nos-1in a dynamic fashion until the embryonic 200-cell stage.
22	skr-15	F54D10.1	n/a	chrII 3,824,456	The skr-15 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-15(RNAi) animals are at least superficially normal.
23	C16A3.2	C16A3.2	n/a	chrIII 6,390,183	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
24	C35D10.13	C35D10.13	n/a	chrIII 4,877,976
25	F32D1.7	F32D1.7	n/a	chrV 4,375,562	contains similarity to Interpro domain IPR005405 (Potassium channel, voltage dependent, Kv3.4)
26	F48C1.5	F48C1.5	n/a	chrI 5,317,876
27	rgs-9	ZC53.7	n/a	chrX 1,916,166	C. elegans RGS-9 protein; contains similarity to Interpro domains IPR015905 (Isoleucyl-tRNA synthetase, class Ia, N-terminal), IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)
28	ZK829.9	ZK829.9	n/a	chrIV 11,971,563	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
29	F54D10.5	F54D10.5	n/a	chrII 3,807,652
30	nhr-263	F10G2.9	n/a	chrV 7,341,043	C. elegans NHR-263 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
31	F40F11.3	F40F11.3	n/a	chrIV 11,592,569	contains similarity to Saccharomyces cerevisiae involved intracellular protein transport, coiled-coil protein necessary for protein transport from ER to Golgi; SGD:YDL058W
32	ZK643.2	ZK643.2	n/a	chrIII 8,957,012	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR016192 (APOBEC/CMP deaminase, zinc-binding), IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016473 (dCMP deaminase), IPR016193 (Cytidine deaminase-like), IPR015517 (Cytidine deaminase)
33	Y37D8A.19	Y37D8A.19	n/a	chrIII 12,930,534	contains similarity to Hordeum vulgare Nonspecific lipid-transfer protein 4.3 precursor (LTP 4.3).; SW:NL43_HORVU
34	clec-222	C03E10.6	n/a	chrV 11,271,884	C. elegans CLEC-222 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
35	B0304.4	B0304.4	n/a	chrII 4,522,834
36	meg-1	K02B9.1	n/a	chrX 13,928,257	meg-1 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-1 activity via mutation and RNAi indicates that MEG-1 is required for germline development and normal levels of fertility; specifically, MEG-1 is required maternally for normal germ cell proliferation and/or survival and for fully normal P granule segregation to the germ cell lineage; in regulating germline development, meg-1 likely functions redundantly with meg-2 and mes-1; meg-1 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; meg-1 mRNA is expressed in the proximal germline; MEG-1 localizes to P granules from the 4-to-8-cell through 100-cell stage of embryogenesis; MEG-1 localization to P granules partially requires MES-1 and, in turn, MES-1 localization to P granules is partly dependent on MEG-1.
37	C53B7.2	C53B7.2	n/a	chrX 6,846,844	C53B7.2 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; C53B7.2 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; C53B7.2 has no obvious function in mass RNAi assays.
38	F17E9.4	F17E9.4	n/a	chrIV 8,348,753
39	F27C8.6	F27C8.6	n/a	chrIV 9,587,998	F27C8.6 encodes a putative arylacetamide deacetylase and microsomal lipase; F27C8.6 is required for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; F27C8.6(RNAi) hermaphrodites are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them.
40	F41C6.3	F41C6.3	n/a	chrX 6,870,780
41	B0393.3	B0393.3	n/a	chrIII 4,758,450	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR006553 (Leucine-rich repeat, cysteine-containing subtype)
42	btb-6	F45C12.7	n/a	chrII 1,715,821	C. elegans BTB-6 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
43	K03H1.7	K03H1.7	n/a	chrIII 9,947,654	contains similarity to Saccharomyces cerevisiae major low affinity 55 kDa Centromere/microtubule binding protein; SGD:YLR175W
44	fbxa-170	C36C9.3	n/a	chrX 1,677,298	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
45	E02H4.6	E02H4.6	n/a	chrX 14,251,350	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
46	mex-6	AH6.5	n/a	chrII 9,525,192	mex-6 encodes a CCCH zinc-finger protein highly similar to MEX-5 that functions with MEX-5 to affect embryonic viability, establish soma germline asymmetry in embryos and establish PIE-1, MEX-1, and POS-1 asymmetry in embryos, and also affects formation of intestinal cells; MEX-6 and MEX-5 may act downstream of the PAR proteins.
47	F31B9.3	F31B9.3	n/a	chrX 15,924,034	contains similarity to Homo sapiens Similar to polymerase (RNA) III; ENSEMBL:ENSP00000334758
48	F19H6.4	F19H6.4	n/a	chrX 12,366,324	contains similarity to Pfam domain PF02544 3-oxo-5-alpha-steroid 4-dehydrogenase contains similarity to Interpro domains IPR013838 (Beta tubulin, autoregulation binding site), IPR001104 (3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal), IPR016636 (3-oxo-5-alpha-steroid 4-dehydrogenase)
49	F14D2.11	F14D2.11	n/a	chrII 3,341,568	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
50	D1086.7	D1086.7	n/a	chrV 14,084,866	contains similarity to Synechocystis sp Hypothetical protein slr1028.; TR:P73139