UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T11F9.12	T11F9.12	0	chrV 11,494,950	contains similarity to Interpro domain IPR011735 (Conserved hypothetical protein, HtrL)
2	W03C9.5	W03C9.5	n/a	chrII 11,967,205	contains similarity to Arabidopsis thaliana F25C20.11 protein.; TR:Q9SAA3
3	T16H12.2	T16H12.2	n/a	chrIII 10,086,574	contains similarity to Mus musculus 2310010I16Rik protein.; TR:Q9CWH8
4	T20B6.2	T20B6.2	n/a	chrIII 2,895,298	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR003125 (Protein of unknown function WSN)
5	mut-7	ZK1098.8	n/a	chrIII 9,540,593	mut-7 encodes a homolog of RnaseD that represses transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages; also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers; cellular fractionation experiments indicate that MUT-7 is expressed in adult worms, and resides in a complex in both the cytosol and nucleus; in the cytosolic complex, MUT-7 interacts with RDE-2, a novel protein also required for RNA interference.
6	nhr-51	K06B4.1	n/a	chrV 15,677,024	C. elegans NHR-51 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
7	JC8.7	JC8.7	n/a	chrIV 13,248,845	contains similarity to Homo sapiens Uncharacterized protein C4orf27; ENSEMBL:ENSP00000261511
8	F28F8.7	F28F8.7	n/a	chrV 15,579,943	contains similarity to Pfam domain PF01448 ELM2 domain contains similarity to Interpro domain IPR000949 (ELM2)
9	T12A2.1	T12A2.1	n/a	chrIII 6,261,458	contains similarity to Pfam domains PF01979 (Amidohydrolase family) , PF07969 (Amidohydrolase family) contains similarity to Interpro domains IPR011550 (Amidohydrolase-like), IPR013108 (Amidohydrolase 3), IPR006680 (Amidohydrolase 1), IPR005920 (Imidazolonepropionase)
10	srh-184	D1054.12	n/a	chrV 10,797,485	C. elegans SRH-184 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	T12F5.2	T12F5.2	n/a	chrI 3,732,139
12	dgk-3	F54G8.2	n/a	chrIII 9,165,462	dgk-3 encodes a diacylglycerol kinase that is the C. elegans ortholog of mammalian DGK-beta; dgk-3 activity is required for regulation of long-term thermotactic behavioral plasticity and for regulation of olfactory adaptation; large-scale expression studies have reported dgk-3 expression in head neurons, the intestine, and the pharyngeal lumen, while expression profiling indicates that dgk-3 is expressed in the AFD thermosensory neurons as well as a small number of additional sensory neurons.
13	srw-69	F18E3.5	n/a	chrV 7,428,134	C. elegans SRW-69 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
14	F13G3.10	F13G3.10	n/a	chrI 7,313,972	contains similarity to Interpro domain IPR010989 (t-SNARE)
15	mdf-1	C50F4.11	n/a	chrV 9,542,977	mdf-1 encodes a coiled-coil domain-containing protein that is orthologous to the Saccharomyces cerevisiae mitotic spindle checkpoint protein Mad1p; consistent with a role as a checkpoint protein, MDF-1 is required in C. elegans for mitotic genome stability and hence, long-term survival and fertility; in vitro, MDF-1 interacts with MDF-2, the C. elegans Mad2p ortholog.
16	C35C5.6	C35C5.6	n/a	chrX 11,566,764	contains similarity to Drosophila melanogaster Flybase gene name is CG2478-PA;; FLYBASE:CG2478
17	mys-1	VC5.4	n/a	chrV 7,083,085	mys-1 encodes a MYST family histone acetyltransferase orthologous to Drosophila EG0007.7, human TIP60, and S. cerevisiae Esa1p; during vulval development, mys-1 acts as Class C synMuv gene: mys-1 mutations enhance mutations in components of the C. elegans NuRD and Rb repressor complexes that negatively regulate expression of genes required for vulval induction; in addition, mys-1(RNAi) enhances mutations in pha-4, which encodes a FoxA transcription factor required for pharyngeal organogenesis; mys-1 mutations also cause a synthetic slow growth phenotype in combination with mutations in the MCD-1 zinc-finger protein; thus, mys-1 activity is essential for proper cell fate specification of different cell types at different times during C. elegans development.
18	str-114	F59B1.1	n/a	chrV 3,650,602	C. elegans STR-114 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
19	nhr-103	F44C8.4	n/a	chrV 2,226,236	nhr-103 encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain.
20	K03H6.4	K03H6.4	n/a	chrIV 1,519,644
21	F57B10.9	F57B10.9	n/a	chrI 6,551,594	F57B10.9 is orthologous to the human gene SPARTIN (TAHCCP1; OMIM:607111), which when mutated leads to disease.
22	srx-93	F59B1.3	n/a	chrV 3,620,070	C. elegans SRX-93 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR001411 (Tetracycline resistance protein, TetB)
23	his-32	F17E9.10	n/a	chrIV 8,334,513	his-32 encodes an H3 histone; by homology, HIS-32 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-32 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
24	T23C6.3	T23C6.3	n/a	chrX 17,137,111
25	cee-1	F26F4.1	n/a	chrIII 4,913,131	C. elegans CEE-1 protein; contains similarity to Pfam domain PF04190 Protein of unknown function (DUF410) contains similarity to Interpro domain IPR007317 (Protein of unknown function DUF410)
26	fbxa-185	F47H4.4	n/a	chrV 17,333,561	C. elegans FBXA-185 protein; contains similarity to Pfam domains PF01485 (IBR domain) , PF00097 (Zinc finger, C3HC4 type (RING finger)) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002867 (Zinc finger, C6HC-type)
27	nud-2	R11A5.2	n/a	chrI 7,858,613	nud-2 encodes an ortholog of human NDE1 (OMIM:609449) and NDEL1 (OMIM:607538), effectors of LIS1 (OMIM:601545); NUD-2, along with other orthologs of LIS1-associated proteins (NUD-1, DHC-1, CDK-5, and CDKA-1), is required to prevent convulsions induced by exposure to the GABA antagonist pentylenetetrazole (PTZ); nud-2(RNAi), like RNAi of nud-1 et al., not only induces PTZ susceptibility but also causes GABA-containing synaptic vesicles in the ventral nerve cord to be distributed raggedly, and nud-2(RNAi) animals are abnormally susceptible to paralysis by the GABA agonist muscimol; nud-2(RNAi) phenotypes are dominantly enhanced by a heterozygous lis-1 allele, and nud-2(RNAi) delays the recovery from PTZ-induced paralysis of lis-1 heterozygotes.
28	F14F9.3	F14F9.3	n/a	chrV 5,139,826	contains similarity to Interpro domain IPR002867 (Zinc finger, C6HC-type)
29	lgc-17	T01H10.6	n/a	chrX 12,123,239	C. elegans LGC-17 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
30	F02C12.3	F02C12.3	n/a	chrX 13,397,291
31	C47E12.2	C47E12.2	n/a	chrIV 10,002,723	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR002030 (Mitochondrial brown fat uncoupling protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
32	T26A5.8	T26A5.8	n/a	chrIII 6,462,478	contains similarity to Pfam domain PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone contains similarity to Interpro domains IPR009072 (Histone-fold), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
33	R09E12.6	R09E12.6	n/a	chrV 767,566	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
34	F10D2.8	F10D2.8	n/a	chrV 7,150,438	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
35	clec-190	M199.4	n/a	chrIV 15,125,488	C. elegans CLEC-190 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
36	B0507.7	B0507.7	n/a	chrV 8,757,284	contains similarity to Pfam domains PF04960 (Glutaminase) , PF00023 (Ankyrin repeat) (2)contains similarity to Interpro domains IPR015868 (Glutaminase, core), IPR007043 (Glutaminase), IPR012338 (Beta-lactamase-type transpeptidase fold), IPR002110 (Ankyrin)
37	hum-1	F29D10.4	n/a	chrI 8,848,443	hum-1 encodes a class I unconventional myosin heavy chain that, within this class, is most closely related to the amoeboid myosin I subclass; loss of hum-1 activity via RNAi results in a low frequency of aldicarb resistance, suggesting that hum-1 may play a role in regulating synapse structure and/or function; when expressed in the DA cholinergic motor neurons, a HUM-1 reporter fusion protein localizes solely to punctate structures.
38	srj-21	F28H7.11	n/a	chrV 10,745,530	C. elegans SRJ-21 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	sulp-1	C55B7.6	n/a	chrI 6,484,156	sulp-1 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-1 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-1::GFP transcriptional fusion is expressed strongly in several neurons, weakly in hypodermal cells and the intestine, and very faintly in the excretory cell and body wall muscle.
40	prg-2	C01G5.2	n/a	chrIV 6,528,248	C. elegans PRG-2 protein; contains similarity to Pfam domains PF02171 (Piwi domain) , PF02170 (PAZ domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
41	C37A2.6	C37A2.6	n/a	chrI 6,788,535	contains similarity to Pfam domain PF06325 Ribosomal protein L11 methyltransferase (PrmA) contains similarity to Interpro domain IPR010456 (Ribosomal L11 methyltransferase)
42	age-1	B0334.8	n/a	chrII 11,523,196	age-1 encodes the C. elegans ortholog of the phosphoinositide 3-kinase (PI3K) p110 catalytic subunit; AGE-1, supplied maternally and embryonically, is a central component of the C. elegans insulin-like signaling pathway, lying downstream of the DAF-2/insulin receptor and upstream of both the PDK-1 and AKT-1/AKT-2 kinases and the DAF-16 forkhead type transcription factor, whose negative regulation is the key output of the insulin signaling pathway; in accordance with its role in insulin signaling, AGE-1 activity is required for regulation of metabolism, life span, dauer formation, stress resistance, salt chemotaxis learning, fertility, and embryonic development; although the age-1 expression pattern has not yet been reported, ectopic expression studies indicate that pan-neuronal age-1 expression is sufficient to rescue life-span defects, while neuronal, intestinal, or muscle expression can partially rescue dauer formation, and neuronal or muscle expression can rescue metabolic defects.
43	clec-102	F33E2.3	n/a	chrI 12,579,521	C. elegans CLEC-102 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
44	srg-22	Y25C1A.10	n/a	chrII 3,092,472	C. elegans SRG-22 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
45	T26E4.1	T26E4.1	n/a	chrV 15,780,361	contains similarity to Pfam domain PF01030 (Receptor L domain)
46	F54D12.4	F54D12.4	n/a	chrII 1,368,200
47	gpa-11	C16A11.1	n/a	chrII 4,254,160	gpa-11 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADL and ASH amphid neurons.
48	C15C6.3	C15C6.3	n/a	chrI 12,209,642	contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR000694 (Proline-rich region)
49	cdk-5	T27E9.3	n/a	chrIII 13,465,418	cdk-5 encodes a putative homolog of cyclin dependent kinase 5 that affects pronuclear migration and rotation in one-cell embryos and may affect neuronal development; expressed in neurons.
50	scl-21	Y43F8B.5	n/a	chrV 19,495,187	C. elegans SCL-21 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)