UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T11F8.1	T11F8.1	3e-144	chrIV 5,480,072
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	cpr-3	T10H4.12	n/a	chrV 15,297,739	C. elegans CPR-3 protein; contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR000668 (Peptidase C1A, papain C-terminal)
5	T22C1.11	T22C1.11	n/a	chrI 7,967,828	contains similarity to Oryctolagus cuniculus Trichohyalin.; SW:P37709
6	srx-56	C03G6.2	n/a	chrV 7,374,979	C. elegans SRX-56 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
7	K12B6.8	K12B6.8	n/a	chrV 6,310,389	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
8	srz-100	T25E12.11	n/a	chrV 16,732,494	C. elegans SRZ-100 protein ;
9	Y62H9A.2	Y62H9A.2	n/a	chrX 11,877,730	contains similarity to Homo sapiens Angiomotin; ENSEMBL:ENSP00000305557
10	twk-2	T12C9.3	n/a	chrII 4,447,199	twk-2 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-2 in C. elegans development and/or behavior is not yet known, but TWK-2 may function redundantly with other TWK channels; TWK-2 is expressed in a subset of neurons.
11	ceh-48	C17H12.9	n/a	chrIV 6,813,828	ceh-48 encodes a ONECUT class CUT homeobox protein with a single N-terminal cut domain; the cut domain may be a compact DNA-binding domain composed of alpha helices; CEH-48 is strongly affiliated with, and may be orthologous to, Drosophila ONECUT and mammalian HNF6 proteins; ceh-48 has no obvious function in mass RNAi assays.
12	F56H6.1	F56H6.1	n/a	chrI 12,281,908	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
13	F32D8.3	F32D8.3	n/a	chrV 10,887,380	F32D8.3 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; F32D8.3 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; F32D8.3 has no obvious function in mass RNAi assays.
14	fbxb-98	C16C4.6	n/a	chrII 1,863,210	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
15	W04A8.3	W04A8.3	n/a	chrI 13,845,353	contains similarity to Plasmodium falciparum Reticulocyte-binding protein, putative.; TR:Q8I4R2
16	F35E8.13	F35E8.13	n/a	chrV 15,925,673	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
17	R06B9.1	R06B9.1	n/a	chrII 13,764,398	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
18	ZC443.1	ZC443.1	n/a	chrV 12,809,256	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
19	ZC581.3	ZC581.3	n/a	chrI 6,653,325	contains similarity to Interpro domain IPR011046 (WD40 repeat-like)
20	ric-3	T14A8.1	n/a	chrIV 7,819,689	The ric-3 gene encodes a novel, highly charged protein with two transmembrane domains and extensive coiled-coil domains; it is necessary for the function of at least four nicotinic acetylcholine receptors; specifically, it is needed for assembly or trafficking of the DEG-3 nicotinic acetylcholine receptor.
21	Y57G11B.1	Y57G11B.1	n/a	chrIV 14,550,857	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
22	C06A5.6	C06A5.6	n/a	chrI 5,984,551
23	sri-53	ZC239.10	n/a	chrII 3,201,906	C. elegans SRI-53 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
24	ZK20.1	ZK20.1	n/a	chrII 11,647,844	contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
25	thn-1	F28D1.3	n/a	chrIV 12,380,448	C. elegans THN-1 protein; contains similarity to Pfam domain PF00314 Thaumatin family contains similarity to Interpro domain IPR001938 (Thaumatin, pathogenesis-related)
26	T15D6.8	T15D6.8	n/a	chrI 12,390,358	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
27	sra-37	T21H8.2	n/a	chrX 13,892,086	C. elegans SRA-37 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
28	cyb-2.1	Y43E12A.1	n/a	chrIV 10,986,675	C. elegans CYB-2.1 protein; contains similarity to Pfam domains PF00134 (Cyclin, N-terminal domain) , PF02984 (Cyclin, C-terminal domain) contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR004367 (Cyclin, C-terminal), IPR014400 (Cyclin, A/B/D/E)
29	Y106G6H.16	Y106G6H.16	n/a	chrI 10,475,167	contains similarity to Salmonella typhimurium Putative cytoplasmic protein (STMF1.42 protein).; TR:Q9L9K2
30	gmd-2	F56H6.5	n/a	chrI 12,293,092	gmd-2 encodes one of two C. elegans GDP-mannose dehydratases; in vitro, and when coexpressed with GER-1, GMD-2 catalyzes the formation of GDP-fucose from GDP-mannose; gmd-2 transcripts are generally present throughout larval and adult stages.
31	F14H12.8	F14H12.8	n/a	chrX 4,363,765
32	C03A7.12	C03A7.12	n/a	chrV 5,179,902	contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
33	C01G12.5	C01G12.5	n/a	chrII 14,586,920	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
34	B0454.8	B0454.8	n/a	chrII 3,042,189	contains similarity to Pfam domain PF02795 Domain of unknown function (DUF225) contains similarity to Interpro domain IPR004024 (Protein of unknown function DUF225)
35	F57C7.4	F57C7.4	n/a	chrX 10,585,230	contains similarity to Interpro domain IPR008972 ()
36	R12E2.14	R12E2.14	n/a	chrI 4,150,308	contains similarity to Interpro domain IPR004051 (Potassium channel, voltage dependent, Kv1.4)
37	his-42	F08G2.3	n/a	chrII 13,828,401	his-42 encodes an H3 histone.
38	Y106G6E.4	Y106G6E.4	n/a	chrI 10,222,213	contains similarity to Pfam domain PF01812 5-formyltetrahydrofolate cyclo-ligase family contains similarity to Interpro domain IPR002698 (5-formyltetrahydrofolate cyclo-ligase)
39	C09H10.5	C09H10.5	n/a	chrII 11,101,400	contains similarity to Mus musculus Similar to serine/threonine kinase 24 (Ste20, yeast homolog).; TR:Q99KH8
40	ugt-32	F47C10.6	n/a	chrV 3,842,918	C. elegans UGT-32 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
41	srx-84	F35B12.1	n/a	chrV 11,599,872	C. elegans SRX-84 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
42	srp-1	C05E4.3	n/a	chrV 754,193	srp-1 encodes an ovalbumin-like serpin (ov-serpin) member of the serine protease inhibitor superfamily; by homology, SRP-1 is predicted to function as a suicide substrate that inhibits the proteolytic activity of serine proteases; however, as loss of srp-1 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of SRP-1 in C. elegans development and/or behavior is not yet known.
43	C01G6.4	C01G6.4	n/a	chrII 9,272,092	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
44	C08B6.5	C08B6.5	n/a	chrV 10,118,697	contains similarity to Danio rerio Glutamate receptor delta-2 subunit precursor (GluR delta-2).; SW:Q68Y21
45	F23F1.6	F23F1.6	n/a	chrII 36,279	contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR004755 (Cationic amino acid transport permease), IPR004841 (Amino acid permease-associated region), IPR002293 (Amino acid/polyamine transporter I)
46	Y116A8B.4	Y116A8B.4	n/a	chrIV 17,224,339	contains similarity to Clostridium acetobutylicum Predicted membrane protein.; TR:Q97KC4
47	acl-1	F59F4.4	n/a	chrX 15,850,758	acl-1 encodes a 1-acyl-sn-glycerol-3-phosphate acyltransferase; ACL-1 is predicted to be a membrane protein that plays a role in phospholipid biosynthesis, but as loss of acl-1 activity via large-scale RNAi experiments results in no obvious defects, the precise role of ACL-1 in C. elegans development and/or behavior is not yet known.
48	T25D10.4	T25D10.4	n/a	chrII 6,408,988
49	spp-6	T08A9.10	n/a	chrX 7,317,449	spp-6 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-6 is predicted to function as a lipid-binding protein that may possess pore-forming, cytotoxic activity; as loss of SPP-6 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of SPP-6 in C. elegans development and/or behavior is not yet known.
50	asm-1	B0252.2	n/a	chrII 6,911,299	asm-1 encodes a protein similar to human acid sphingomyelinase (ASM) or sphingomyelin phosphodiesterase; the ASM-1 protein has a putative secretory signal peptide at the N-terminus, saposin-like and proline-rich domains and putative N-linked glycosylation sites; asm-1 shows phosphodiesterase activity when expressed in COS-7 cells; while mammalian ASM is detected as both intracellular and secreted forms, asm-1 was detected exclusively in the secreted form; northern blot analysis indicates that asm-1 is expressed at higher levels in the embryo compared with other stages.