UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	str-96	T10H4.2	0	chrV 15,293,203	C. elegans STR-96 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
2	K06A1.3	K06A1.3	n/a	chrII 6,442,625	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
3	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	dhc-1	T21E12.4	n/a	chrI 4,394,384	dhc-1 encodes a cytoplasmic dynein heavy chain homolog required in one-cell embryos for pronuclear migration, centrosome separation, centrosome proximity to the male pronucleus, and mitotic spindle orientation, suggesting that DHC-1 helps position the microtubule organizing center; DHC-1 genetically interacts with SPD-5, a coiled-coil centrosomal protein.
5	R06F6.6	R06F6.6	n/a	chrII 10,807,531	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR013847 (POU), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
6	C01H6.6	C01H6.6	n/a	chrI 7,223,298	C01H6.6 encodes a predicted transmembrane protein orthologous to human ACDP1-ACDP4 and S. cerevisiae MAM3, and paralogous to C33D12.2, C52D10.12, M02F4.3, R04E5.2, and R13G10.4; by orthology with MAM3, C01H6.6 may participate in metal homoeostasis; C01H6.6, MAM3, and ACDP1-ACDP4 belong to a family of proteins (sharing an ACD domain) from bacteria, yeast, plants, and metazoa; murine Acdp1 is a plasma membrane protein; bacterial proteins containing the ACD domain include CorC from Salmonella typhimurium, which is involved in magnesium and cobalt efflux; C01H6.6 has no obvious function in RNAi assays.
7	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
8	R07H5.10	R07H5.10	n/a	chrIV 11,214,469	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
9	grd-8	C37C3.4	n/a	chrV 7,843,402	grd-8 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; GRD-8 is expressed in larval intestine and neurons; the grd-8 gene is directly bound by DAF-12 and requires DAF-12 for full transcription; GRD-8's Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-8 is weakly required for normal molting; GRD-8 is also required for normal adult alae formation, growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
10	srd-31	F07C4.8	n/a	chrV 7,634,059	C. elegans SRD-31 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	ets-5	C42D8.4	n/a	chrX 5,080,670	C. elegans ETS-5 protein; contains similarity to Pfam domain PF00178 Ets-domain contains similarity to Interpro domains IPR000418 (Ets), IPR011991 (Winged helix repressor DNA-binding)
12	srh-105	T27A1.7	n/a	chrII 508,784	C. elegans SRH-105 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	tpi-1	Y17G7B.7	n/a	chrII 12,038,108	tpi-1 encodes a putative triosephosphate isomerase orthologous to human TPI1 (OMIM:190450, mutated in TPI deficiency) and Drosophila WASTED AWAY; despite the severity of TPI mutant phenotypes in humans and Drosophila, TPI-1 has no obvious function in mass RNAi assays.
14	D1007.3	D1007.3	n/a	chrI 4,576,495
15	F10D11.4	F10D11.4	n/a	chrI 8,441,960	contains similarity to Interpro domain IPR005819 (Histone H5)
16	srsx-38	T26E4.14	n/a	chrV 15,806,689	C. elegans SRSX-38 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
17	ZK892.4	ZK892.4	n/a	chrII 10,007,287	ZK892.4 is orthologous to the human gene ALPHA-METHYLACYL-CoA RACEMASE (AMACR; OMIM:604489), which when mutated leads to AMACR deficiency.
18	ZC132.5	ZC132.5	n/a	chrV 4,306,648	contains similarity to Pfam domain PF05380 Pao retrotransposon peptidase contains similarity to Interpro domains IPR008042 (Retrotransposon, Pao), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
19	F52C9.3	F52C9.3	n/a	chrIII 5,324,039	contains similarity to Pfam domain PF00781 Diacylglycerol kinase catalytic domain (presumed) contains similarity to Interpro domain IPR001206 (Diacylglycerol kinase, catalytic region)
20	sec-24.2	ZC518.2	n/a	chrIV 12,358,176	C. elegans SEC-24.2 protein; contains similarity to Pfam domains PF04811 (Sec23/Sec24 trunk domain) , PF04815 (Sec23/Sec24 helical domain) , PF04810 (Sec23/Sec24 zinc finger) , PF00626 (Gelsolin repeat) , PF08033 (Sec23/Sec24 beta-sandwich domain) contains similarity to Interpro domains IPR006900 (Sec23/Sec24 helical region), IPR012990 (Sec23/Sec24 beta-sandwich), IPR000694 (Proline-rich region), IPR006896 (Sec23/Sec24 trunk region), IPR006895 (Zinc finger, Sec23/Sec24-type), IPR007123 (Gelsolin region)
21	twk-25	M04B2.5	n/a	chrIV 11,507,989	C. elegans TWK-25 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
22	F02C9.2	F02C9.2	n/a	chrV 3,135,542	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domains IPR005049 (Protein of unknown function DUF288), IPR002972 (Prostaglandin D synthase)
23	T10D4.1	T10D4.1	n/a	chrII 3,151,352	contains similarity to Pfam domains PF01579 (Domain of unknown function DUF19) , PF02343 (Domain of unknown function DUF130) contains similarity to Interpro domains IPR003326 (Protein of unknown function DUF130), IPR002542 (Protein of unknown function DUF19)
24	C26D10.4	C26D10.4	n/a	chrII 8,331,544	contains similarity to Pfam domains PF08544 (GHMP kinases C terminal) , PF00288 (GHMP kinases N terminal domain) contains similarity to Interpro domains IPR006206 (Mevalonate and galactokinase), IPR001174 (Galactokinase/homoserine kinase), IPR006204 (GHMP kinase), IPR014721 (Ribosomal protein S5 domain 2-type fold), IPR013750 (GHMP kinase, C-terminal)
25	srh-212	T22F3.6	n/a	chrV 3,596,155	C. elegans SRH-212 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR001463 (Sodium:alanine symporter), IPR003002 (7TM chemoreceptor, subfamily 1)
26	ZK402.2	ZK402.2	n/a	chrX 1,403,926	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
27	sra-3	AH6.7	n/a	chrII 9,539,969	C. elegans SRA-3 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
28	F40G12.2	F40G12.2	n/a	chrV 14,260,215	contains similarity to Interpro domain IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site)
29	T08G3.7	T08G3.7	n/a	chrV 16,464,369	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00023 (Ankyrin repeat) , PF00533 (BRCA1 C Terminus (BRCT) domain) contains similarity to Interpro domains IPR002110 (Ankyrin), IPR003125 (Protein of unknown function WSN), IPR001357 (BRCT)
30	srt-67	B0238.5	n/a	chrV 5,256,766	C. elegans SRT-67 protein; contains similarity to Pfam domains PF01461 (7TM chemoreceptor) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002651 (Protein of unknown function DUF32)
31	cyp-34A10	B0213.16	n/a	chrV 3,971,866	C. elegans CYP-34A10 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
32	clec-156	F26A1.11	n/a	chrIII 4,842,010	C. elegans CLEC-156 protein; contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
33	F37C4.2	F37C4.2	n/a	chrIV 3,887,244	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
34	C50F7.9	C50F7.9	n/a	chrIV 7,731,347
35	F31E9.3	F31E9.3	n/a	chrV 17,323,648	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
36	fbxa-102	K03D7.7	n/a	chrV 17,492,710	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
37	F41C6.7	F41C6.7	n/a	chrX 6,883,839	contains similarity to Pfam domain PF01545 Cation efflux family contains similarity to Interpro domain IPR002524 (Cation efflux protein)
38	T07H6.5	T07H6.5	n/a	chrX 6,288,966	contains similarity to Pfam domain PF00084 Sushi domain (SCR repeat) contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
39	F39D8.3	F39D8.3	n/a	chrX 15,423,577	contains similarity to Homo sapiens Sperm-specific thioredoxin; ENSEMBL:ENSP00000304908
40	R07H5.9	R07H5.9	n/a	chrIV 11,208,377	contains similarity to Saccharomyces cerevisiae involved in septin organization; SGD:YCL024W
41	hmit-1.2	Y51A2D.5	n/a	chrV 18,526,923	hmit-1.2 encodes one of three C. elegans proton (H+)-dependent myo-inositol transporters; loss of hmit-1.2 activity via large-scale RNAi result in no obvious abnormalities but by homology, HMIT-1.2 is predicted to function as a plasma membrane protein required for the regulated uptake of myo-inositol and thus potentially for regulation of cell signaling and intracellular osmolarity.
42	R173.3	R173.3	n/a	chrX 7,033,107	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
43	C18F10.2	C18F10.2	n/a	chrIII 6,274,532	contains similarity to Schizosaccharomyces pombe Sporulation-specific protein 15.; SW:Q10411
44	K06H6.2	K06H6.2	n/a	chrV 586,550	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
45	K07H8.7	K07H8.7	n/a	chrIV 8,259,664	contains similarity to Interpro domain IPR000079 (High mobility group protein HMG14 and HMG17)
46	srx-35	T01C4.5	n/a	chrV 7,121,587	C. elegans SRX-35 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR000276 (GPCR, rhodopsin-like)
47	pat-10	F54C1.7	n/a	chrI 5,019,533	pat-10 encodes body wall muscle troponin C, the calcium-binding component of the troponin complex of actin thin filaments; PAT-10 is essential for muscle contraction and thus for completion of embryonic morphogenesis and elongation; by homology, PAT-10 likely functions to regulate body wall muscle contraction in response to changes in intracellular calcium; PAT-10 is expressed in body wall muscle but is also detected in vulval and anal muscles; expression in body wall muscle begins during early embryonic morphogenesis, concurrent with expression of other body wall muscle structural components.
48	K09F5.1	K09F5.1	n/a	chrX 7,740,721
49	M02D8.5	M02D8.5	n/a	chrX 8,757,529	contains similarity to Interpro domain IPR000859 (CUB)
50	fbxa-111	Y102A5C.14	n/a	chrV 16,949,135	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.