UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	cpr-3	T10H4.12	0	chrV 15,297,739	C. elegans CPR-3 protein; contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR000668 (Peptidase C1A, papain C-terminal)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	T11F8.1	T11F8.1	n/a	chrIV 5,480,072
5	srx-56	C03G6.2	n/a	chrV 7,374,979	C. elegans SRX-56 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
6	twk-2	T12C9.3	n/a	chrII 4,447,199	twk-2 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; the precise role of TWK-2 in C. elegans development and/or behavior is not yet known, but TWK-2 may function redundantly with other TWK channels; TWK-2 is expressed in a subset of neurons.
7	ZC443.1	ZC443.1	n/a	chrV 12,809,256	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
8	K12B6.8	K12B6.8	n/a	chrV 6,310,389	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
9	Y62H9A.2	Y62H9A.2	n/a	chrX 11,877,730	contains similarity to Homo sapiens Angiomotin; ENSEMBL:ENSP00000305557
10	F14H12.8	F14H12.8	n/a	chrX 4,363,765
11	sra-37	T21H8.2	n/a	chrX 13,892,086	C. elegans SRA-37 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
12	ric-3	T14A8.1	n/a	chrIV 7,819,689	The ric-3 gene encodes a novel, highly charged protein with two transmembrane domains and extensive coiled-coil domains; it is necessary for the function of at least four nicotinic acetylcholine receptors; specifically, it is needed for assembly or trafficking of the DEG-3 nicotinic acetylcholine receptor.
13	C03A7.12	C03A7.12	n/a	chrV 5,179,902	contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
14	F32D8.3	F32D8.3	n/a	chrV 10,887,380	F32D8.3 encodes a putative secreted TIL-domain protease inhibitor paralogous to SWM-1, ISL-1, and the products of 11 other C. elegans genes; F32D8.3 and its relatives are collectively similar to other TIL-domain protease inhibitors from nematodes, insects, and vertebrates; F32D8.3 has no obvious function in mass RNAi assays.
15	ulp-1	T10F2.3	n/a	chrIII 5,167,689	C. elegans ULP-1 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
16	T22C1.11	T22C1.11	n/a	chrI 7,967,828	contains similarity to Oryctolagus cuniculus Trichohyalin.; SW:P37709
17	F42A9.6	F42A9.6	n/a	chrIV 8,610,474
18	Y57G11B.1	Y57G11B.1	n/a	chrIV 14,550,857	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2EJ43
19	F57C7.4	F57C7.4	n/a	chrX 10,585,230	contains similarity to Interpro domain IPR008972 ()
20	T15D6.8	T15D6.8	n/a	chrI 12,390,358	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
21	ech-5	F56B3.5	n/a	chrIV 798,439	C. elegans ECH-5 protein; contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domain IPR001753 (Crotonase, core)
22	C06A5.6	C06A5.6	n/a	chrI 5,984,551
23	R06B9.1	R06B9.1	n/a	chrII 13,764,398	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR000698 (Arrestin), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
24	sago-1	K12B6.1	n/a	chrV 6,306,024	sago-1 encodes an Argonaute homolog that is partially required for the amplification phase of RNAi responses; a multiply mutant strain (MAGO), consisting of ppw-1(tm914), sago-1(tm1195), sago-2(tm894), F58G1.1(tm1019), C06A1.4(tm887), and M03D4.6(tm1144) alleles, is completely resistant to both germline and somatic RNAi; sago-1 is genetically redundant with ppw-1 and sago-2, with any one of these genes being able to transgenically partially restore the deficiency of MAGO worms; GFP-tagged SAGO-1 binds small secondary siRNAs produced by RNAi against GFP; MAGO is not transgenically rescued by rde-1; strains overexpressing GFP::SAGO-1 exhibited an enhanced level of RNAi overall, suggesting that SAGO-1 and its congeners are rate-limiting in vivo for RNAi.
25	ZC581.3	ZC581.3	n/a	chrI 6,653,325	contains similarity to Interpro domain IPR011046 (WD40 repeat-like)
26	srx-84	F35B12.1	n/a	chrV 11,599,872	C. elegans SRX-84 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
27	F35E8.13	F35E8.13	n/a	chrV 15,925,673	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
28	srd-26	T02B5.4	n/a	chrV 14,162,174	C. elegans SRD-26 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	acl-1	F59F4.4	n/a	chrX 15,850,758	acl-1 encodes a 1-acyl-sn-glycerol-3-phosphate acyltransferase; ACL-1 is predicted to be a membrane protein that plays a role in phospholipid biosynthesis, but as loss of acl-1 activity via large-scale RNAi experiments results in no obvious defects, the precise role of ACL-1 in C. elegans development and/or behavior is not yet known.
30	C42C1.2	C42C1.2	n/a	chrIV 12,266,886	contains similarity to Pfam domain PF00481 Protein phosphatase 2C contains similarity to Interpro domains IPR001932 (Protein phosphatase 2C-related), IPR000222 (), IPR014045 (Protein phosphatase 2C, N-terminal), IPR015655 (Protein phosphatase 2C)
31	C08B6.5	C08B6.5	n/a	chrV 10,118,697	contains similarity to Danio rerio Glutamate receptor delta-2 subunit precursor (GluR delta-2).; SW:Q68Y21
32	thn-1	F28D1.3	n/a	chrIV 12,380,448	C. elegans THN-1 protein; contains similarity to Pfam domain PF00314 Thaumatin family contains similarity to Interpro domain IPR001938 (Thaumatin, pathogenesis-related)
33	F46G11.2	F46G11.2	n/a	chrX 5,789,196
34	spp-6	T08A9.10	n/a	chrX 7,317,449	spp-6 encodes a predicted transmembrane protein containing a saposin (B) domain that is a member of a saposin-like protein superfamily containing mammalian NK-lysin and granulysin and the protozoan amoebapores; SPP-6 is predicted to function as a lipid-binding protein that may possess pore-forming, cytotoxic activity; as loss of SPP-6 function via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of SPP-6 in C. elegans development and/or behavior is not yet known.
35	C18D4.4	C18D4.4	n/a	chrV 17,530,973	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
36	cyp-37B1	F28G4.1	n/a	chrV 16,279,374	C. elegans CYP-37B1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
37	K12D9.12	K12D9.12	n/a	chrV 3,021,212	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
38	C01G6.4	C01G6.4	n/a	chrII 9,272,092	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
39	srz-100	T25E12.11	n/a	chrV 16,732,494	C. elegans SRZ-100 protein ;
40	T25D10.4	T25D10.4	n/a	chrII 6,408,988
41	F23F1.6	F23F1.6	n/a	chrII 36,279	contains similarity to Pfam domain PF00324 Amino acid permease contains similarity to Interpro domains IPR004755 (Cationic amino acid transport permease), IPR004841 (Amino acid permease-associated region), IPR002293 (Amino acid/polyamine transporter I)
42	T16A9.3	T16A9.3	n/a	chrV 14,208,326	contains similarity to Pfam domain PF06887 Protein of unknown function (DUF1265) contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR009676 (Protein of unknown function DUF1265)
43	str-232	T10C6.1	n/a	chrV 16,015,103	C. elegans STR-232 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
44	C50B8.1	C50B8.1	n/a	chrV 13,566,397	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
45	cyb-2.1	Y43E12A.1	n/a	chrIV 10,986,675	C. elegans CYB-2.1 protein; contains similarity to Pfam domains PF00134 (Cyclin, N-terminal domain) , PF02984 (Cyclin, C-terminal domain) contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal), IPR004367 (Cyclin, C-terminal), IPR014400 (Cyclin, A/B/D/E)
46	T09F5.1	T09F5.1	n/a	chrV 15,149,875	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
47	ref-1	T01E8.2	n/a	chrII 10,219,169	ref-1 encodes a protein with two basic helix-loop-helix (bHLH) domains that is distantly related to the hairy/Enhancer of split subfamily of bHLH transcription factors; REF-1 is required in hermaphrodites during early larval development for regulating the pattern of posterior Pn.p hypodermal cell fusions, primarily through regulation of MAB-5 homeodomain protein activity; REF-1 is also required for head morphogenesis and specification of the V6 lateral seam cell fate; in males, ref-1 is a target of MAB-3 transcriptional repression which in turn, promotes expression of LIN-32, a proneural bHLH transcription factor.
48	T28C6.8	T28C6.8	n/a	chrIV 8,830,136	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
49	Y37D8A.4	Y37D8A.4	n/a	chrIII 12,837,949	contains similarity to Pfam domain PF00017 SH2 domain contains similarity to Interpro domain IPR000980 (SH2 motif)
50	asm-1	B0252.2	n/a	chrII 6,911,299	asm-1 encodes a protein similar to human acid sphingomyelinase (ASM) or sphingomyelin phosphodiesterase; the ASM-1 protein has a putative secretory signal peptide at the N-terminus, saposin-like and proline-rich domains and putative N-linked glycosylation sites; asm-1 shows phosphodiesterase activity when expressed in COS-7 cells; while mammalian ASM is detected as both intracellular and secreted forms, asm-1 was detected exclusively in the secreted form; northern blot analysis indicates that asm-1 is expressed at higher levels in the embryo compared with other stages.