UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T10G3.1	T10G3.1	2e-165	chrV 13,471,322	contains similarity to Saccharomyces cerevisiae interacts with Sin1p; SGD:YER047C
2	T26G10.5	T26G10.5	n/a	chrIII 9,426,015	contains similarity to Streptococcus pyogenes Hypothetical protein SPy0952.; TR:Q9A032
3	K02A6.2	K02A6.2	n/a	chrX 8,224,536
4	T07D1.3	T07D1.3	n/a	chrX 2,443,181	contains similarity to Interpro domain IPR016160 (Aldehyde dehydrogenase, conserved site)
5	nlp-31	B0213.6	n/a	chrV 3,980,323	nlp-31 encodes five predicted neuropeptide-like proteins; in C. elegans, nlp-31 is part of the YGGWamide neuropeptide family that also contains nlp-24, nlp-25, and nlp-27-32; nlp-31 is expressed in the hypodermis, suggesting that the peptides it encodes may have a non-neuronal function; nlp-31 expression is also detected in precomma-stage embryos; as loss of nlp-31 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of the nlp-31-encoded peptides in development and/or behavior is not yet known.
6	flp-24	C24A1.1	n/a	chrIII 725,550	C. elegans FLP-24 protein ;
7	M60.7	M60.7	n/a	chrX 8,259,771	contains similarity to Pfam domains PF07525 (SOCS box) , PF00023 (Ankyrin repeat) (9)contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001496 (SOCS protein, C-terminal)
8	ttr-29	R90.4	n/a	chrV 12,906,429	C. elegans TTR-29 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
9	K01A2.10	K01A2.10	n/a	chrII 322,278	contains similarity to Homo sapiens Coiled-coil domain-containing protein 92; ENSEMBL:ENSP00000238156
10	C14A6.2	C14A6.2	n/a	chrV 18,151,568	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR001991 (Sodium:dicarboxylate symporter), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
11	far-3	F15B9.1	n/a	chrV 12,997,151	C. elegans FAR-3 protein; contains similarity to Pfam domain PF05823 Nematode fatty acid retinoid binding protein (Gp-FAR-1) contains similarity to Interpro domain IPR008632 (Nematode fatty acid retinoid binding)
12	fipr-23	C37A5.4	n/a	chrI 14,153,722	C. elegans FIPR-23 protein ; contains similarity to Homo sapiens Keratin-associated protein 20-2; ENSEMBL:ENSP00000330746
13	F11C1.4	F11C1.4	n/a	chrX 12,979,059	contains similarity to Drosophila melanogaster Flybase gene name is CG9186-PA;; FLYBASE:CG9186
14	pqn-98	ZK488.7	n/a	chrV 603,936	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
15	lact-6	C06A12.5	n/a	chrIV 17,430,817	lact-6 encodes a beta-lactamase domain-containing protein that contains a predicted signal sequence in its N terminus.
16	ZC443.2	ZC443.2	n/a	chrV 12,810,803	contains similarity to Listeria innocua Hypothetical protein lin2372.; TR:Q929A5
17	gbh-2	M05D6.7	n/a	chrII 8,486,654	gbh-2 encodes an ortholog of human gamma butyrobetaine hydroxilase 2 involved in carnitine biosynthesis; RNA interference of gbh-2 results in malformation of the gonad and accumulation of fat in the pseudocoelomic cavity and in intestinal cells; the GBH-2-GFP fusion protein is predominantly expressed in intestinal cells from early embryogenesis.
18	C08E8.4	C08E8.4	n/a	chrV 18,372,276	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domain IPR012816 (Conserved hypothetical protein CHP02464)
19	zig-5	Y48A6A.1	n/a	chrIII 10,952,247	zig-5 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-5::gfp reporter fusion is expressed in a number of neurons, including PVT, VD1-13, RID, AFD, ASK, RIV, RIB, PVQ, DVA, and RIS; zig-5::gfp is detected in the PVT neuron beginning at the three-fold stage of embryogenesis and continuing throughout larval development; loss of zig-5 activity in large-scale RNAi screens has been reported to result in low levels of embryonic lethality.
20	W09G12.7	W09G12.7	n/a	chrIV 1,230,204	contains similarity to Interpro domains IPR005819 (Histone H5), IPR002038 (Osteopontin)
21	ins-11	C17C3.4	n/a	chrII 5,556,897	ins-11 encodes an insulin-like peptide of the insulin superfamily of proteins (OMIM:176730, 147440); INS-11 is one of 38 insulin-like peptides in C. elegans and is expressed in the labial sensory neurons, the nerve ring, and other neurons; although the precise role of INS-11 in C. elegans development is not yet clear, loss of INS-11 function via RNA-mediated interference can result in animals that are smaller than wild type (Sma).
22	F47B8.4	F47B8.4	n/a	chrV 14,324,002	contains similarity to Pfam domain PF00462 Glutaredoxin contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR012336 (Thioredoxin-like fold)
23	nlp-5	F35C11.1	n/a	chrII 8,243,059	C. elegans NLP-5 protein ;
24	grd-9	C04E6.6	n/a	chrV 5,896,978	grd-9 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-9 is weakly required for normal molting; GRD-9 is also required for normal growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
25	F53F4.7	F53F4.7	n/a	chrV 13,613,185	contains similarity to Pfam domain PF03407 Protein of unknown function (DUF271) contains similarity to Interpro domain IPR005069 (Protein of unknown function DUF271)
26	C32H11.3	C32H11.3	n/a	chrIV 12,919,384	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
27	tyr-3	F21C3.2	n/a	chrI 7,276,425	C. elegans TYR-3 protein; contains similarity to Pfam domains PF00264 (Common central domain of tyrosinase) , PF01549 (ShK domain-like) (4)contains similarity to Interpro domains IPR008922 (Di-copper centre-containing), IPR002227 (Tyrosinase), IPR003582 (Metridin-like ShK toxin)
28	F52E1.8	F52E1.8	n/a	chrV 8,393,368	contains similarity to Pfam domains PF00300 (Phosphoglycerate mutase family) , PF00328 (Histidine acid phosphatase) contains similarity to Interpro domains IPR000560 (Histidine acid phosphatase), IPR013078 (Phosphoglycerate mutase)
29	T24F1.5	T24F1.5	n/a	chrII 11,319,376	contains similarity to Bombyx mori Lebocin 1/2 precursor.; SW:LEB1_BOMMO
30	zig-3	C14F5.2	n/a	chrX 7,931,218	zig-3 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-3::gfp reporter fusion is expressed in the PVT, AIM, and ASI neurons, as well as in the vulva and weakly in the body wall muscle.
31	nlp-8	D2005.2	n/a	chrI 7,801,131	C. elegans NLP-8 protein ;
32	tag-243	T04A8.4	n/a	chrIII 4,686,618	C. elegans TAG-243 protein; contains similarity to Interpro domain IPR000637 (HMG-I and HMG-Y, DNA-binding)
33	ins-18	T28B8.2	n/a	chrI 8,148,533	ins-18 encodes one of 40 C. elegans insulin/IGF-like peptides; INS-18, along with INS-1, are the only two C. elegans insulins that contain a C peptide, characteristic of mammalian insulins, connecting the B and A chains; overexpression of ins-18 induces dauer arrest at 26 degrees C and enhances the dauer arrest seen in a daf-2 mutant at 20 degrees C, suggesting that INS-18 functions to antagonize DAF-2 receptor signaling; ins-18::gfp reporters are expressed in neurons and the intestine.
34	T27E4.1	T27E4.1	n/a	chrV 9,093,497	contains similarity to Interpro domain IPR008973 (C2 calcium/lipid-binding region, CaLB)
35	W10G11.1	W10G11.1	n/a	chrII 3,560,174	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
36	F47E1.2	F47E1.2	n/a	chrX 9,059,694	contains similarity to Pfam domain PF03137 Organic Anion Transporter Polypeptide (OATP) family contains similarity to Interpro domains IPR004156 (Organic anion transporter polypeptide OATP), IPR016196 (MFS general substrate transporter)
37	ttr-27	R90.2	n/a	chrV 12,903,803	C. elegans TTR-27 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
38	F19F10.1	F19F10.1	n/a	chrV 7,563,460	contains similarity to Pfam domain PF00178 Ets-domain contains similarity to Interpro domains IPR000418 (Ets), IPR011991 (Winged helix repressor DNA-binding)
39	F18G5.6	F18G5.6	n/a	chrX 9,263,128
40	F35E2.3	F35E2.3	n/a	chrI 11,735,172	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
41	C07A9.8	C07A9.8	n/a	chrIII 9,688,522	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
42	K01D12.10	K01D12.10	n/a	chrV 12,406,600	contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR003072 (Orphan nuclear receptor, NOR1 type), IPR003982 (Leukotriene B4 type 2 receptor)
43	fipr-22	C37A5.2	n/a	chrI 14,155,893	C. elegans FIPR-22 protein ; contains similarity to Homo sapiens Keratin-associated protein 20-2; ENSEMBL:ENSP00000330746
44	flp-21	C26F1.10	n/a	chrV 7,793,674	flp-21 encodes a single FMRFamide-related neuropeptide (FaRP) that serves as a ligand for NPR-1, a G protein-coupled receptor that regulates social versus solitary feeding behavior in several Caenorhabditis species; genetic analysis suggests that FLP-21 acts through NPR-1 to inhibit social feeding behavior; FLP-21 is expressed in the ADL, ASE and ASH sensory neurons, the URA motor neurons, the MC, M2 and M4 pharyngeal neurons, and the intestine; flp-21 encodes the only FMRFamide-related neuropeptide (FaRP) encoded by the C. elegans genome that activates both the social (215F) and the solitary (215V) forms of NPR-1 in both Xenopus oocytes and pharyngeal assays.
45	cnc-4	R09B5.9	n/a	chrV 1,447,465	cnc-4 encodes one of six C. elegans caenacin peptides; cnc-4 expression is strongly induced after infection by the fungus Drechmeria coniospora, suggesting that it functions as a secreted antimicrobial peptide in the innate immune response.
46	fbxa-24	F54D10.2	n/a	chrII 3,817,370	C. elegans FBXA-24 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
47	T21C12.3	T21C12.3	n/a	chrIII 10,538,504	contains similarity to Leptospira interrogans Hypothetical protein.; TR:Q8EZD2
48	nhr-260	C38C3.9	n/a	chrV 1,510,828	C. elegans NHR-260 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
49	F58B4.3	F58B4.3	n/a	chrV 10,930,269	contains similarity to Homo sapiens similar to bA88M19.1 (EGF-like-domain multiple 5 protein); ENSEMBL:ENSP00000223618
50	T28A11.5	T28A11.5	n/a	chrV 3,270,895	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR003559 (Cytolethal distending toxin C), IPR002542 (Protein of unknown function DUF19)