UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	T10E9.8	T10E9.8	1e-85	chrI 6,540,502
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	C53B7.6	C53B7.6	n/a	chrX 6,868,654
4	str-28	F25E5.12	n/a	chrV 7,472,264	C. elegans STR-28 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	mel-26	ZK858.4	n/a	chrI 9,134,137	mel-26 encodes a MATH and BTB/POZ domain-containing protein that functions as a novel substrate-specific adaptor of the CUL-3-containing E3 ubiquitin ligase; MEL-26 is required maternally for formation of mitotic spindles in the early embryo, and as a component of a ubiquitin ligase complex, for degradation of the microtubule-severing protein MEI-1 at the meiosis to mitosis transition; MEL-26 is also required maternally for embryonic morphogenesis; since MEL-26 contains a meprin-associated Traf homology (MATH) domain, it might be involved in apoptosis.
6	F48C1.4	F48C1.4	n/a	chrI 5,313,536
7	ZK470.4	ZK470.4	n/a	chrX 4,139,617
8	ing-3	Y51H1A.4	n/a	chrII 13,879,211	Y51H1A.4 is orthologous to the human gene P33ING1B (ING1; OMIM:601566), which when mutated leads to disease.
9	F55C5.1	F55C5.1	n/a	chrV 12,263,644	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
10	W06D12.1	W06D12.1	n/a	chrV 17,736,716	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
11	F56H6.12	F56H6.12	n/a	chrI 12,313,605	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
12	W05H5.1	W05H5.1	n/a	chrII 12,443,814	contains similarity to Ovis aries Lysophosphatidic acid receptor Edg-2 (LPA receptor 1) (LPA-1).; SW:EDG2_SHEEP
13	T06G6.5	T06G6.5	n/a	chrI 12,716,111	contains similarity to Interpro domain IPR007087 (Zn-finger, C2H2 type)
14	EEED8.6	EEED8.6	n/a	chrII 5,385,733	EEED8.6 encodes an ATP/ADP-activated metallocarboxypeptidase, orthologous to mammalian AGBL4 proteins, that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; recombinant EEED8.6 is active in vitro on several different C-terminal amino acids of synthetic peptide substrates (with carboxypeptidase A- and B-like, but not O-like specificity); unlike most carboxypeptidases, but like tubulin carboxypeptidase, EEED8.6 is inhibited by high salt or by Z-Glu-Tyr dipeptide; EEED8.6 and its mammalian AGBL4 orthologs, along with other proteins such as mammalian AGBL5, comprise a M14D2 peptidase subfamily; by homolog-based structural modelling, EEED8.6 is predicted to have an unusually open active site.
15	lips-1	F45E6.4	n/a	chrX 12,494,285	C. elegans LIPS-1 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
16	F09G8.5	F09G8.5	n/a	chrIII 8,256,200	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal), IPR010916 (TonB box, conserved site)
17	clec-242	Y68A4B.2	n/a	chrV 17,244,604	C. elegans CLEC-242 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
18	aat-4	T13A10.10	n/a	chrIV 6,274,136	aat-4 encodes a predicted amino acid transporter catalytic subunit; unlike catalytic subunits in other organisms, however, AAT-4 does not contain the highly conserved cysteine residue known to facilitate covalent interaction with a glycoprotein subunit, suggesting that AAT-4 does not require this residue for heterodimer formation or, alternatively, does not require the glycoprotein subunit for function.
19	nhr-271	T03E6.3	n/a	chrV 16,579,462	C. elegans NHR-271 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
20	srsx-8	F52F10.5	n/a	chrV 1,552,074	C. elegans SRSX-8 protein ;
21	Y39F10A.2	Y39F10A.2	n/a	chrII 780,543	contains similarity to Pfam domain PF06079 Apyrase contains similarity to Interpro domain IPR009283 (Apyrase)
22	srw-26	T05G11.3	n/a	chrV 15,931,865	C. elegans SRW-26 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
23	Y116A8C.22	Y116A8C.22	n/a	chrIV 17,047,371	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
24	F54E7.6	F54E7.6	n/a	chrIII 5,660,439
25	Y54E2A.6	Y54E2A.6	n/a	chrII 14,768,030	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) (2), PF00271 (Helicase conserved C-terminal domain) (2), PF02889 (Sec63 Brl domain) (2)contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR004179 (Sec63), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
26	str-166	T08B6.6	n/a	chrIV 4,885,569	C. elegans STR-166 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	btb-5	W05G11.5	n/a	chrIII 60,257	C. elegans BTB-5 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
28	srx-116	W05B10.5	n/a	chrV 12,671,795	C. elegans SRX-116 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
29	Y57G11A.3	Y57G11A.3	n/a	chrIV 14,502,754	contains similarity to Pfam domain PF00412 LIM domain contains similarity to Interpro domain IPR001781 (Zinc finger, LIM-type)
30	Y6B3B.4	Y6B3B.4	n/a	chrI 13,765,684	contains similarity to Interpro domain IPR000533 (Tropomyosin)
31	ZK1240.5	ZK1240.5	n/a	chrII 2,317,121	contains similarity to Interpro domain IPR000315 (Zinc finger, B-box)
32	F45G2.10	F45G2.10	n/a	chrIII 13,438,200	contains similarity to Pfam domain PF01883 Domain of unknown function DUF59 contains similarity to Interpro domain IPR002744 (Protein of unknown function DUF59)
33	F08C6.5	F08C6.5	n/a	chrX 7,560,915	contains similarity to Interpro domain IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site)
34	glr-8	F22A3.3	n/a	chrX 6,508,340	glr-8 encodes a highly divergent putative ionotropic glutamate receptor subunit, unclassifiable as NMDA or non-NMDA (though possibly of the Delta subfamily), and without any clear close homologs in metazoa or plants; glr-8 is expressed in the pharyngeal nervous system, the body wall mechanoreceptors ALM and PLM, and two other neurons (BDU and URB); glr-8 is expressed from embryogenesis to adulthood.
35	F11C3.1	F11C3.1	n/a	chrI 14,869,588	contains similarity to Xenopus laevis ATP-dependent DNA helicase PIF1 (EC 3.6.1.-).; SW:Q0R4F1
36	F34D6.2	F34D6.2	n/a	chrII 2,683,818	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000047 (Helix-turn-helix motif, lambda-like repressor), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
37	glb-10	C29F5.7	n/a	chrII 6,308,800	glb-10 encodes a globin; glb-10 is expressed in pharynx, intestine, vulval muscle, and many neurons, with at least some subcellular localization to synapses; however, glb-10 has no obvious function in mass RNAi assays.
38	srw-73	T03E6.6	n/a	chrV 16,587,756	C. elegans SRW-73 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
39	W09D6.5	W09D6.5	n/a	chrIII 11,089,923	contains similarity to Saccharomyces cerevisiae cell wall integrity and stress response component 1; SGD:YOR008C
40	Y49F6C.2	Y49F6C.2	n/a	chrII 3,379,231
41	H03G16.1	H03G16.1	n/a	chrX 15,054,187	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
42	K03D10.3	K03D10.3	n/a	chrI 14,122,952	The K03D10.3 gene encodes a MYST acetyltransferase orthologous to the Drosophila MALES-ABSENT-ON-THE-FIRST (MOF) and CG1894 proteins, the human MOF protein, and the S. cerevisiae SAS2 protein.
43	set-24	Y43F11A.5	n/a	chrII 12,122,894	set-24 encodes a protein with an N-terminal SET domain, followed by two SPK domains; SET-24's domain organization resembles that of SET-5, but SET-24 has no known non-nematode orthologs or C. elegans paralogs; neither set-24(n4909) nor set-24(RNAi) have any obvious phenotypes.
44	srd-40	F17A2.12	n/a	chrX 12,324,508	C. elegans SRD-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	bath-33	C08E3.3	n/a	chrII 1,605,408	C. elegans BATH-33 protein; contains similarity to Pfam domains PF00917 (MATH domain) , PF00651 (BTB/POZ domain) contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
46	Y43F8B.11	Y43F8B.11	n/a	chrV 19,471,547	contains similarity to Campylobacter coli CadF precursor (Outer membrane protein).; TR:O06895
47	scl-18	T12A7.3	n/a	chrIV 11,754,015	C. elegans SCL-18 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR002413 (Ves allergen), IPR001283 (Allergen V5/Tpx-1 related), IPR002052 (N-6 adenine-specific DNA methylase, conserved site)
48	F36H12.17	F36H12.17	n/a	chrIV 5,277,187
49	srv-11	H25K10.3	n/a	chrIV 16,220,615	C. elegans SRV-11 protein; contains similarity to Pfam domains PF01461 (7TM chemoreceptor) , PF01748 (Caenorhabditis serpentine receptor-like protein) contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002651 (Protein of unknown function DUF32)
50	C50C3.7	C50C3.7	n/a	chrIII 8,160,210	contains similarity to Pfam domain PF03372 Endonuclease/Exonuclease/phosphatase family contains similarity to Interpro domains IPR000300 (Inositol polyphosphate related phosphatase), IPR005135 (Endonuclease/exonuclease/phosphatase)