UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	his-2	T10C6.13	1.0000000000000001e-71	chrV 16,041,899	his-2 encodes an H3 histone; his-2 is contained within the histone gene cluster HIS1.
2	ZC204.2	ZC204.2	n/a	chrII 1,664,783	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
3	his-59	F55G1.2	1.0000000000000001e-71	chrIV 7,488,436	his-59 encodes an H3 histone; by homology, HIS-59 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-59 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
4	T28F2.2	T28F2.2	n/a	chrI 3,638,075	contains similarity to Homo sapiens Isoform 2 of COMM domain-containing protein 4; ENSEMBL:ENSP00000340867
5	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
6	fzr-1	ZK1307.6	n/a	chrII 9,642,652	fzr-1 encodes a WD repeat-containing protein homologous to Cdh1/Hct1/FZR (OMIM:603619), a regulatory subunit of the anaphase-promoting complex/cyclosome (APC/C) required for anaphase initiation and exit from mitosis; FZR-1 is required for fertility, and also functions redundantly with lin-35/Rb to for normal embryogensis and control of postembryonic cell proliferation; FZR-1 probably regulates the levels of G1 cyclins, degradation of which is critical for G1 arrest.
7	C31E10.6	C31E10.6	n/a	chrX 13,997,720	contains similarity to Saccharomyces cerevisiae Mlp proteins restrict telomere length by influencing the Rif1-Tel1 pathway of telomerase regulation; also involved in the translocation of macromolecules between the nucleoplasm and the NPC; SGD:YKR095W
8	pix-1	K11E4.4	n/a	chrX 13,730,745	C. elegans PIX-1 protein ;
9	hnd-1	C44C10.8	n/a	chrX 11,685,111	hnd-1 encodes a Hand bHLH transcription factor required for normal viability, gonadogenesis, and posterior body morphology; HND-1 is required for the formation of both somatic gonadal precursors and primordial germ cells, but not for later gonadogenesis; HND-1 is expressed embryogenesis in embryonic mesodermal precursor cells generating (mostly) body wall muscle, in somatic gonad precursor cells, and in some unidentified head cells; the primary defect in hnd-1 mutants may be, nonautonomously, in mesodermal precursor cells; somatic gonad precursor cells are normally generated in hnd-1 mutants, but not maintained.
10	sdz-30	T04D3.2	n/a	chrI 13,307,433	C. elegans SDZ-30 protein; contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
11	R11E3.2	R11E3.2	n/a	chrIV 4,773,617	contains similarity to Pfam domain PF00860 Permease family contains similarity to Interpro domain IPR006043 (Xanthine/uracil/vitamin C permease)
12	C03C10.5	C03C10.5	n/a	chrIII 4,090,398	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8IEF0
13	lnp-1	C05E11.1	n/a	chrX 4,589,579	lnp-1 encodes a highly conserved protein of unknown function, orthologous to human LUNAPARK/KIAA1715 (OMIM:610236), that is required for normally short body length, normal locomotion, fat content, acetylcholine neurotransmission, localization of RAB-3 and SNB-1, and sensitivity to aldicarb; LNP-1 is expressed in muscles, hypodermal cells, and neurons; within neurons, LNP-1 is localized to cell bodies, neuritic processes and commissures, and requiring UNC-104 for localization outside of cell bodies; LNP-1 is likely to act presynaptically; LNP-1 contains two N-terminal predicted transmembrane sequences, and an atypical zinc finger domain (C2HC2).
14	mab-7	ZC13.4	n/a	chrX 895,155	mab-7 encodes a protein with a hydrophobic type II transmembrane region at the N-terminus, an EGF-like motif, a ShKT motif and a long C-terminus; mab-7 is involved in morphogenesis of the male tail, specifically affecting the structural cells, neuronal processes and the hypodermal sheath of the sensory rays, as such, it affects mating in males; a mab-7 promoter-gfp construct is expressed in hypodermis, body seam, ray structural cells, and several neurons in the head and tail region.
15	his-38	K03A1.6	n/a	chrX 7,309,668	his-38 encodes an H4 histone; by homology, HIS-38 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-38 is a replication-dependent histone locus that does not reside in a cluster, but exists as a single histone locus on the X chromosome.
16	C24B5.4	C24B5.4	n/a	chrV 9,196,537	contains similarity to Pfam domain PF08925 Domain of Unknown Function (DUF1907) contains similarity to Interpro domain IPR015021 (Region of unknown function DUF1907)
17	C14C11.7	C14C11.7	n/a	chrV 5,665,729
18	F31C3.3	F31C3.3	n/a	chrI 15,045,790	contains similarity to Interpro domain IPR001000 (Glycoside hydrolase, family 10)
19	K08H2.2	K08H2.2	n/a	chrX 13,234,539	contains similarity to Homo sapiens Hypothetical protein KIAA0144; ENSEMBL:ENSP00000271877
20	nspb-12	F09F7.8	n/a	chrIII 5,568,450	C. elegans NSPB-12 protein ;
21	kin-29	F58H12.1	n/a	chrX 2,848,198	kin-29 encodes a serine/threonine kinase with significant homology in the kinase domain to the AMP-activated protein kinase (AMPK) and SNF1 kinases; the AMP-kinase cascade is activated by cellular stresses that deplete ATP; AMP-kinase is believed to protect the mammalian cell by 'switching off' ATP-consuming pathways like fatty acid synthesis, by phosphorylating key regulatory enzymes, and switching on alternative pathways for ATP generation; kin-29 is involved in regulating the expression of chemosensory receptors and entry into the daur pathway; kin-29 also affects body size via interaction with the Sma/Mab pathway and lifespan, with mutants exhibiting a smaller body size and increased life span; a functional KIN-29-GFP fusion protein is expressed in sensory neurons and many other cell types, and localizes to the cytoplasm; under conditions of cellular stress like heat shock and starvation, KIN-29-GFP translocates to the nucleus.
22	dpm-3	F28D1.11	n/a	chrIV 12,391,825	dpm-3 encodes a putative regulatory subunit of dolichol phosphate mannosyltransferase, orthologous to human DPM3 (OMIM:605951); in mass RNAi assays, DPM-3 is required for normal body size, fertility, and health.
23	F09E5.11	F09E5.11	n/a	chrII 5,357,780	F09E5.11 encodes a divergent ortholog of S. cerevisiae VPH2/VMA12; like VPH2, F09E5.11 may be required for vacuolar proton-translocating ATPase (V-ATPase) assembly in the endoplasmic reticulum.
24	C50H11.13	C50H11.13	n/a	chrV 3,070,772	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
25	C27B7.7	C27B7.7	n/a	chrIV 8,911,257	contains similarity to Pfam domains PF00047 (Immunoglobulin domain) , PF00041 (Fibronectin type III domain) (6)contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR013783 (Immunoglobulin-like fold), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR003962 (Fibronectin, type III subdomain), IPR013151 (Immunoglobulin)
26	Y65A5A.3	Y65A5A.3	n/a	chrIV 16,416,285	contains similarity to Human papillomavirus type 13 Probable E4 protein.; SW:VE4_HPV13
27	F39G3.2	F39G3.2	n/a	chrV 4,739,477	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
28	sdz-38	ZK892.7	n/a	chrII 9,981,301	C. elegans SDZ-38 protein; contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
29	F08D12.7	F08D12.7	n/a	chrII 2,768,193	F08D12.7 encodes a novel protein conserved amongst Caenorhaditis species; although loss of F08D12.7 activity via RNAi results in no obvious defects, F08D12.7 transcripts are enriched in L1-stage muscle and upregulated in L2 larvae in response to overexpression of hlh-2 and hlh-8; in addition, in analyses of the early embryonic transcriptome, F08D12.7 transcripts are classified as strictly maternal; an F08D12.7::gfp reporter fusion is expressed in the vm1 and vm2 vulval muscles, the intestinal and anal depressor muscles, the hypodermis, distal tip cell, ventral nerve cord, head and tail neurons, and body wall muscle.
30	his-56	F54E12.3	n/a	chrIV 11,338,648	his-56 encodes an H4 histone.
31	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
32	R06B9.4	R06B9.4	n/a	chrII 13,754,197	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
33	srg-3	C18F10.6	n/a	chrIII 6,269,673	C. elegans SRG-3 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
34	ttr-35	F22A3.2	n/a	chrX 6,512,558	C. elegans TTR-35 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
35	C53D6.4	C53D6.4	n/a	chrIV 9,020,038	contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR013766 (Thioredoxin domain)
36	K04F10.7	K04F10.7	n/a	chrI 6,367,224	contains similarity to Homo sapiens Isoform 1 of Protein FAM76B; ENSEMBL:ENSP00000351631
37	col-70	H17B01.2	n/a	chrII 1,471,156	C. elegans COL-70 protein; contains similarity to Interpro domain IPR000694 (Proline-rich region)
38	F26A1.9	F26A1.9	n/a	chrIII 4,825,812
39	T10B5.2	T10B5.2	n/a	chrV 1,849,449
40	str-255	C45H4.15	n/a	chrV 2,162,667	C. elegans STR-255 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000301 (CD9/CD37/CD63 antigen)
41	fbxb-14	W08F4.9	n/a	chrII 582,428	C. elegans FBXB-14 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
42	T24B8.2	T24B8.2	n/a	chrII 9,055,661	contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
43	dao-3	K07E3.3	n/a	chrX 8,085,329	dao-3 encodes a protein containing tetrahydrofolate dehydrogenase/cyclohydrolase catalytic and NAD(P)-binding domains; by similarity to mammalian enzymes, DAO-3 is predicted to function in one-carbon unit metabolism and thus, in amino acid and nucleotide biosynthesis; dao-3 expression appears to be regulated by daf-2-mediated insulin signaling: microarray experiments suggest that it is upregulated in daf-2 mutant adults, while differential display and Northern analyses suggest that it is down-regulated; a dao-3 promoter gfp fusion is expressed in larvae in the hypodermis and in the nervous system, including tail neurons and phasmids.
44	F38E11.9	F38E11.9	n/a	chrIV 9,443,446	contains similarity to Musca domestica Transposase.; TR:Q25442
45	cdh-3	ZK112.7	n/a	chrIII 7,747,815	cdh-3 encodes a member of the cadherin superfamily that affects morphogenesis of tail epithelia and excretory function; expressed predominantly in developing epithelial cells, and also expressed in the AC, excretory cell, various neurons, and vulval cells during different stages of development.
46	R03E9.2	R03E9.2	n/a	chrX 6,731,598	contains similarity to Interpro domain IPR001220 (Legume lectin, beta domain)
47	F11A5.6	F11A5.6	n/a	chrV 16,203,986	contains similarity to Bradyrhizobium japonicum Bll7368 protein.; TR:Q89DS1
48	srw-61	H25K10.7	n/a	chrIV 16,237,697	C. elegans SRW-61 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor)
49	ZK563.5	ZK563.5	n/a	chrX 3,378,206	contains similarity to Aedes aegypti Putative uncharacterized protein.; TR:Q17A46
50	R11.1	R11.1	n/a	chrX 16,192,348	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)