UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	pcbd-1	T10B11.1	1e-79	chrI 6,951,540	T10B11.1 is orthologous to the human gene PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE (PCBD or TCF1; OMIM:126090), which when mutated leads to hyperphenylalaninemia with primapterinuria.
2	clec-50	W04E12.8	n/a	chrV 19,749,271	C. elegans CLEC-50 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR000480 (Glutelin), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002353 (Type II antifreeze protein)
3	R144.6	R144.6	n/a	chrIII 5,003,956	contains similarity to Pfam domain PF07857 CEO family (DUF1632) contains similarity to Interpro domain IPR012435 (Protein of unknown function DUF1632)
4	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
5	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
6	B0281.4	B0281.4	n/a	chrII 2,298,366	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
7	C34D4.13	C34D4.13	n/a	chrIV 7,133,813
8	T22C1.5	T22C1.5	n/a	chrI 7,941,375	contains similarity to Saccharomyces cerevisiae Iswi One Complex; SGD:YMR044W
9	nhr-155	C14C6.4	n/a	chrV 540,344	C. elegans NHR-155 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
10	srx-1	F59E11.1	n/a	chrV 9,004,313	C. elegans SRX-1 protein; contains similarity to Interpro domains IPR000366 (Fungal pheromone mating factor STE2 GPCR), IPR000276 (GPCR, rhodopsin-like)
11	T21C9.4	T21C9.4	n/a	chrV 10,578,742	contains similarity to Pfam domain PF01133 Enhancer of rudimentary contains similarity to Interpro domain IPR000781 (Enhancer of rudimentary)
12	F48F5.3	F48F5.3	n/a	chrV 20,448,445	contains similarity to Zea mays Putative zinc finger protein.; TR:Q8LJR1
13	fkh-10	C25A1.2	n/a	chrI 10,164,375	fkh-10 encodes one of 15 forkhead transcriptional regulators encoded by the C. elegans genome; by homology, FKH-10 is predicted to function as a transcription factor that regulates gene expression during development; however, as loss of fkh-10 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of FKH-10 in C. elegans development and/or behavior is not yet known; nevertheless, reporter gene studies indicate that throughout larval and adult stages, fkh-10 expression is detected almost exclusively in six pairs of neuronal nuclei near the terminal bulb of the pharynx, suggesting that FKH-10 may have a specific function in neuronal differentiation.
14	sri-37	D2062.2	n/a	chrII 2,630,401	C. elegans SRI-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
15	F47B10.6	F47B10.6	n/a	chrX 10,888,627
16	F58E6.6	F58E6.6	n/a	chrV 9,752,440	contains similarity to Monosiga brevicollis MBCTL1 (Fragment).; TR:Q7YZI0
17	mls-1	H14A12.4	n/a	chrIII 7,461,052	mls-1 encodes a T-box transcription factor orthologous to members of the Tbx1 subfamily of T-box transcription factors (OMIM:602054, mutations in human TBX1 are associated with the developmental disorder DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS)); MLS-1 is required for fate specification of the eight nonstriated uterine muscle cells generated during postembryonic development, and ectopic expression of MLS-1 is sufficient for uterine muscle specification in other mesodermal lineages; mls-1 reporter gene expression is detected in uterine progenitors and differentiated uterine muscles, Type 2 vulval muscles, the left and right intestinal muscles, and the anal depressor muscle; mls-1 expression is positively regulated by the basic helix-loop-helix transcription factors HLH-8/Twist and HLH-2/Daughterless.
18	Y57G11C.25	Y57G11C.25	n/a	chrIV 14,919,983	Y57G11C.25 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to C. elegans POS-1, the product of Y57G11C.25 is predicted to function as an RNA-binding protein.
19	F16H6.8	F16H6.8	n/a	chrV 18,214,941	contains similarity to Mycoplasma capricolum CLPA/CLPB family (Fragment).; TR:Q49064
20	srw-98	K04F1.3	n/a	chrV 1,677,402	C. elegans SRW-98 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
21	F48G7.9	F48G7.9	n/a	chrV 628,338	contains similarity to Pfam domain PF00130 Phorbol esters/diacylglycerol binding domain (C1 domain) contains similarity to Interpro domains IPR015727 (Protein kinase C mu-related), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
22	clec-235	F36D3.10	n/a	chrV 16,531,589	C. elegans CLEC-235 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
23	H25K10.6	H25K10.6	n/a	chrIV 16,235,400	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
24	Y56A3A.31	Y56A3A.31	n/a	chrIII 11,986,100	contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
25	srh-45	T03F7.2	n/a	chrV 11,304,292	C. elegans SRH-45 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002259 (Delayed-early response protein/equilibrative nucleoside transporter), IPR008075 (Lipocalin-1 receptor)
26	JC8.4	JC8.4	n/a	chrIV 13,243,908	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR016192 (APOBEC/CMP deaminase, zinc-binding), IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016193 (Cytidine deaminase-like)
27	F36G9.3	F36G9.3	n/a	chrV 15,958,350	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF05978 (Eukaryotic protein of unknown function (DUF895)) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
28	R08H2.10	R08H2.10	n/a	chrV 15,373,870	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
29	F02D10.6	F02D10.6	n/a	chrX 13,450,586	contains similarity to Cryptophlebia leucotreta granulosis virus Hypothetical protein.; TR:Q7T5R9
30	srxa-9	ZK678.4	n/a	chrX 15,749,493	C. elegans SRXA-9 protein; contains similarity to Pfam domain PF03383 Caenorhabditis serpentine receptor-like protein, class xa contains similarity to Interpro domain IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
31	srg-7	C18F10.8	n/a	chrIII 6,267,278	C. elegans SRG-7 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
32	clec-223	C03E10.5	n/a	chrV 11,275,618	C. elegans CLEC-223 protein; contains similarity to Pfam domain PF01391 Collagen triple helix repeat (20 copies) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR008160 (Collagen triple helix repeat)
33	R09A8.2	R09A8.2	n/a	chrX 12,621,311	contains similarity to Staphylococcus aureus Serine-rich adhesin for platelets precursor (Staphylococcus aureusssurface protein A).; SW:Q8NUJ3
34	srx-22	F31F4.3	n/a	chrV 680,688	C. elegans SRX-22 protein ;
35	srt-73	T06C10.2	n/a	chrIV 7,880,158	C. elegans SRT-73 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
36	ZC53.1	ZC53.1	n/a	chrX 1,912,323
37	C56E6.2	C56E6.2	n/a	chrII 6,525,580	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras), IPR006036 (Potassium uptake protein TrkA), IPR002078 (RNA polymerase sigma factor 54, interaction)
38	twk-44	Y71H9A.1	n/a	chrX 11,625,639	C. elegans TWK-44 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR011001 (Saposin-like), IPR008139 (Saposin B), IPR013099 (Ion transport 2)
39	unc-39	F56A12.1	n/a	chrV 14,374,572	unc-39 encodes a homeodomain transcription factor that belongs to the Six4/5 family of homeodomain proteins that includes human Six5; UNC-39 is required for axonal pathfinding in anterior-derived neurons and for specification of most mesodermal cell types and may regulate a developmental decision between migration and differentiation; UNC-39 is expressed in the embryo in anterior neurons, posteriorly derived mesoderm (somatic gonad, M mesoblast, and possibly the coelomocytes and muIntR), the CAN neurons, and body wall muscle.
40	srh-55	T09F5.5	n/a	chrV 15,154,261	C. elegans SRH-55 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	R107.2	R107.2	n/a	chrIII 9,044,850	contains similarity to Pfam domain PF01256 Carbohydrate kinase contains similarity to Interpro domain IPR000631 (Carbohydrate kinase)
42	srx-111	T24E12.4	n/a	chrII 3,758,519	C. elegans SRX-111 protein ;
43	ZK1307.2	ZK1307.2	n/a	chrII 9,653,433	contains similarity to Dictyostelium discoideum Hypothetical protein.; TR:Q8T1G2
44	F53F8.5	F53F8.5	n/a	chrV 20,697,686	contains similarity to Pfam domain PF00536 SAM domain (Sterile alpha motif) contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR013761 (Sterile alpha motif-type), IPR001660 (Sterile alpha motif SAM)
45	fbxb-106	F29A7.1	n/a	chrII 2,763,216	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
46	T24E12.2	T24E12.2	n/a	chrII 3,783,547
47	C38D4.9	C38D4.9	n/a	chrIII 4,803,842	contains similarity to Pfam domains PF01170 (Putative RNA methylase family UPF0020) , PF05175 (Methyltransferase small domain) , PF08242 (Methyltransferase domain) contains similarity to Interpro domains IPR007848 (Methyltransferase small), IPR000241 (Putative RNA methylase), IPR002296 (N6 adenine-specific DNA methyltransferase, N12 class), IPR013217 (Methyltransferase type 12), IPR002052 (N-6 adenine-specific DNA methylase, conserved site), IPR002723 (Protein of unknown function DUF43)
48	sdz-36	ZK1251.7	n/a	chrIV 9,691,129	C. elegans SDZ-36 protein
49	C24H10.1	C24H10.1	n/a	chrX 5,073,103	C24H10.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; C24H10.1 is worm-specific, with obvious homologs only in C. elegans; C24H10.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
50	fbxa-56	T12B5.7	n/a	chrIII 937,668	C. elegans FBXA-56 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)